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Condition: Heart Attack
Management: Hospitals

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Total 884 results found since Jan 2013.

General Versus Regional Anesthesia for Carotid Endarterectomy
THE FIRST CAROTID ENDARTERECTOMY (CEA) was performed at St Mary Hospital, London, England, in 1954. This is a surgical procedure performed to reduce the incidences of embolic and thrombotic stroke. The incidence of perioperative stroke during CEA is approximately 2.3%. The incidence of perioperative myocardial infarction (MI), which is defined by Q-wave criteria on an electrocardiogram, in patients undergoing CEA is
Source: Journal of Cardiothoracic and Vascular Anesthesia - January 2, 2013 Category: Anesthesiology Authors: Dragana Unic-Stojanovic, Srdjan Babic, Vojislava Neskovic Tags: Review Articles Source Type: research

Clinical applications of targeted temperature management.
Abstract Targeted temperature management (TTM) has been investigated experimentally and used clinically for over 100 years. The initial rationale for the clinical application of TTM, historically referred to as therapeutic hypothermia, was to decrease the metabolic rate, allowing the injured brain time to heal. Subsequent research demonstrated the temperature dependence of diverse cellular mechanisms including endothelial dysfunction, production of reactive oxygen species, and apoptosis. Consequently, modern use of TTM centers on neuroprotection following focal or global neurologic injury. Despite a solid basic sc...
Source: Chest - February 1, 2014 Category: Respiratory Medicine Authors: Perman SM, Goyal M, Neumar RW, Topjian AA, Gaieski DF Tags: Chest Source Type: research

30-Year Trends in Patient Characteristics, Treatment Practices, and Long-Term Outcomes of Adults Aged 35 to 54 Years Hospitalized With Acute Myocardial Infarction
The objectives of our population-based study were to describe>3-decade-long trends in the clinical features, treatment practices, and long-term outcomes of young adults aged 35 to 54 years discharged from the hospital after AMI. The study population consisted of 2,142 residents of the Worcester (Massachusetts) metropolitan area who were hospitalized with AMI at all central Massachusetts medical centers during 16 annual periods from 1975 to 2007. Our primarily male study population had an average age of 47 years. Patients hospitalized during the most recent decade (1997 to 2007) under study were more likely to have a hist...
Source: The American Journal of Cardiology - January 15, 2014 Category: Cardiology Authors: Mayra Tisminetzky, David D. McManus, Joel M. Gore, Jorge Yarzebski, Andrew Coles, Darleen Lessard, Robert J. Goldberg Tags: Coronary Artery Disease Source Type: research

Dabigatran Use in the Real World: A Multihospital System Experience
Dabigatran etexilate, an oral direct thrombin inhibitor, was approved by the Food and Drug Administration to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation based on the outcomes of the Randomized Evaluation of Long-term anticoagulant therapY (RE-LY) study. Although this study provides robust data on the efficacy and safety of dabigatran, there may be differences in the drug use and outcomes in routine clinical practice following drug approval. In this retrospective chart review study, we describe the use of dabigatran in 160 patients in 4 adult hospitals (1 academic and 3 c...
Source: Journal of Pharmacy Practice - August 4, 2014 Category: Drugs & Pharmacology Authors: Kimmons, L. A., Kabra, R., Davis, M., Segars, B. V., Oliphant, C. S. Tags: Research Articles Source Type: research

The value of CHADS score in predicting new-onset atrial fibrillation in Chinese patients with acute myocardial infarction
Previous studies have shown that new-onset atrial fibrillation (AF) in the setting of acute myocardial infarction (AMI) was associated with increased in-hospital and long term mortality [1,2]. Therefore, it was crucial to recognize the patients with AMI who were on the increased risk for developing new-onset AF. CHADS2 score (congestive heart failure, hypertension, age≥75years, diabetes and previous stroke or transient ischemic attack) was a very useful and convenient scoring system, which was widely used for the stroke risk stratification in the patients with non-valvular AF [3].
Source: International Journal of Cardiology - August 5, 2014 Category: Cardiology Authors: Xiaowei Zhang, Guangping Li, Zhiqiang Zhao, Yanmin Xu, Tong Liu Source Type: research

The impact of global budgeting on treatment intensity and outcomes
Abstract This paper investigates the effects of global budgets on the amount of resources devoted to cardio-cerebrovascular disease patients by hospitals of different ownership types and these patients’ outcomes. Theoretical models predict that hospitals have financial incentives to increase the quantity of treatments applied to patients. This is especially true for for-profit hospitals. If that’s the case, it is important to examine whether the increase in treatment quantity is translated into better treatment outcomes. Our analyses take advantage of the National Health Insurance of Taiwan’s implementation...
Source: International Journal of Health Care Finance and Economics - September 30, 2014 Category: Health Management Source Type: research

The previous use of digoxin does not worsen early outcome of acute coronary syndromes: an analysis of the ARIAM Registry
Abstract The aim of the study was to determine the influence of the previous use of digoxin on the hospital mortality and complications of patients admitted because of acute coronary syndrome (ACS). We analyzed the data of patients included in the ARIAM-Andalucia Registry, which involves 49 hospitals in Andalucia, Spain, from 2007 to 2012. Patients on digoxin treatment prior to their admission because of ACS constituted the digoxin group (DG), and were compared with the group of patients not on digoxin. Logistic regression and propensity score matching were used to analyze the differences. We included 20,331 ...
Source: Internal and Emergency Medicine - October 1, 2014 Category: Emergency Medicine Source Type: research

Influence of gender on the risk of death and adverse events in patients with acute myocardial infarction undergoing pharmacoinvasive strategy
Abstract Pharmacoinvasive treatment is an acceptable alternative for patients with ST-segment elevation myocardial infarction (STEMI) in developing countries. The present study evaluated the influence of gender on the risks of death and major adverse cardiovascular events (MACE) in this population. Seven municipal emergency rooms and the Emergency Mobile Healthcare Service in São Paulo treated STEMI patients with tenecteplase. The patients were subsequently transferred to a tertiary teaching hospital for early (<24 h) coronary angiography. A total of 469 patients were evaluated [329 men (70.1 %)]. Compared ...
Source: Journal of Thrombosis and Thrombolysis - October 2, 2014 Category: Hematology Source Type: research

Clinical characteristics, hospital care, and prognosis of patients with ST elevation myocardial infarction: Hungarian Myocardial Infarction Registry
The authors analyse clinical data, hospital care, and short- and long-term prognosis of 4981 ST segment elevation myocardial infarction (STEMI) patients enrolled in the web-based Hungarian Myocardial Infarction Registry. It has been found that the mean age of STEMI patients was lower by 5.3 years than that of patients treated for non-STEMI (NSTEMI). In the group of NSTEMI patients (n = 3601), the occurrence of diabetes, hypertension, peripheral vascular disease, and previous history of myocardial infarction and stroke were significantly more frequent. The proportion of smokers among STEMI patients was remarkably higher. Pr...
Source: European Journal of Heart Failure Supplements - January 10, 2014 Category: Cardiology Authors: Janosi, A., Ofner, P., Forster, T., Edes, I., Toth, K., Merkely, B. Tags: Articles Source Type: research

Why Are So Many Women Ignoring Heart Attack Symptoms?
Heart disease is a leading cause of death for women, and yet women are more likely than men to dismiss pain or symptoms of heart problems, and to delay seeking medical help -- a "dangerous game" that experts say may have serious health implications. Though heart symptoms are similar for both men and women, the way that people perceive their symptoms and the point at which they are moved to seek medical help can vary widely. Women may be more likely than men to exhibit an 'optimism bias' -- a cognitive bias that causes them to believe they are less at risk for negative outcomes than they actually are -- than men, which ...
Source: Science - The Huffington Post - October 30, 2014 Category: Science Source Type: news

The Efficacy of Fimasartan for Cardiovascular Events and Metabolic Syndrome (K-MetS Study): Rationale, Design and Participant Characteristics
Fimasartan, the eighth angiotensin receptor blocker, was launched in March 2011 and was found to have an excellent efficacy and safety profile in a large cross-sectional population study [Safety and Efficacy of Fimasartan in Patients with Arterial Hypertension (Safe-KanArb); Park et al.: Am J Cardiovasc Drugs 2013;13:47-56]. However, there is no long-term study to evaluate its efficacy for major adverse cardiovascular events (MACE) and other effects. The purpose of this study (K-MetS study) was to evaluate whether the early reduction of blood pressure (BP) and/or correction of metabolic derangements with fimasartan will af...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Risk of venous and arterial thrombotic events in patients diagnosed with superficial vein thrombosis: a nationwide cohort study
We examined this in a nationwide population-based setting during a period when SVT was not treated routinely with anticoagulants. The Danish National Registry of Patients, covering all Danish hospitals, was used to identify 10 973 patients with a first-time diagnosis of SVT between 1980 and 2012. A comparison cohort of 515 067 subjects, matched by age, gender, and calendar year, was selected from the general Danish population. Outcomes were venous thromboembolism, acute myocardial infarction, ischemic stroke, and death. During median follow-up of 7 years, the incidence rate of venous thromboembolism was 18.0/1000 person-ye...
Source: Blood - January 8, 2015 Category: Hematology Authors: Cannegieter, S. C., Horvath-Puho, E., Schmidt, M., Dekkers, O. M., Pedersen, L., Vandenbroucke, J. P., Sorensen, H. T. Tags: Free Research Articles, Thrombosis and Hemostasis, Clinical Trials and Observations Source Type: research

Carotid Stenting—Why Treating an Artery May Not Treat the Patient
In this issue of JAMA Neurology, Jalbert and colleagues present the results of a detailed analysis of Centers for Medicare & Medicaid Services (CMS) administrative data on patients with carotid artery stenosis treated with carotid artery stenting. Their well-written manuscript and timely study included more than 22 000 patients treated and followed up between 2000 and 2009. They analyzed periprocedural complications (defined as stroke, transient ischemic attack [TIA], myocardial infarction [MI], and death within 30 days), as well as long-term stroke and mortality. Important variables that were analyzed included the degre...
Source: JAMA Neurology - January 12, 2015 Category: Neurology Source Type: research

Millions of adults skip medications due to their high cost
Medications can do wonderful things, from fighting infection to preventing stroke and warding off depression. But medications don’t work if they aren’t taken. Some people don’t take their medications as prescribed because they forget, or are bothered by side effects. A new report from the National Center for Health Statistics shines the light on another reason: some people can’t pay for their medications. The survey, by NCHS researchers Robin A. Cohen and Maria A. Villarroel, found that about 8% of adult Americans don’t take their medicines as prescribed because they can’t afford them. I...
Source: New Harvard Health Information - January 30, 2015 Category: Consumer Health News Authors: Howard LeWine, M.D. Tags: Drugs and Supplements medication costs Source Type: news