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Total 992 results found since Jan 2013.

The Impact of Longitudinal Data-Completeness of Electronic Health Record Data on the Prediction Performance of Clinical Risk Scores
Clin Pharmacol Ther. 2023 Apr 7. doi: 10.1002/cpt.2901. Online ahead of print.ABSTRACTThe impact of electronic health record (EHR) discontinuity, i.e., receiving care outside of a given EHR system, on EHR-based risk prediction is unknown. We aimed to assess the impact of EHR-continuity on performance of clinical risk scores. The study cohort consisted of patients aged ≥65 years with ≥1 EHR encounter in the two networks in Massachusetts (MA, 2007/1/1-2017/12/31, internal training and validation dataset), and one network in North Carolina (NC, 2007/1/1-2016/12/31, external validation dataset) that were linked with Medica...
Source: Clinical Pharmacology and Therapeutics - April 7, 2023 Category: Drugs & Pharmacology Authors: Yinzhu Jin Janick G Weberpals Shirley V Wang Rishi J Desai David Merola Kueiyu Joshua Lin Source Type: research

America Has No Way to Take Care of Mentally Ill People
With evermore unhoused people on the streets of our biggest cities, and publicized subway crimes in New York, mental health treatment is again in the news. Politicians speak about “caring” for the mentally ill in a new way, which turns out to be the old way—putting them away. The mention of involuntary confinement, predictably, sparks anxiety and controversy, giving rise to the question of whom this policy is meant to help: the people taken away or the rest of population, those shopping, jogging, carrying groceries home, who, presumably, will no longer be bothered by the inconvenient reality of a person s...
Source: TIME: Health - March 31, 2023 Category: Consumer Health News Authors: Mona Simpson Tags: Uncategorized freelance Psychology Source Type: news

Transcatheter vs Surgical Aortic Valve Replacement in Pure Native Aortic Regurgitation
CONCLUSIONS: In Medicare patients with pure native AR, TAVR with the current commercially available transcatheter valves has comparable short-term outcomes. Although long-term outcomes were inferior to SAVR, the possibility of residual confounding, biasing long-term outcomes, given older and frailer TAVR patients, cannot be excluded.PMID:36967709 | DOI:10.1016/j.athoracsur.2022.09.016
Source: The Annals of Thoracic Surgery - March 27, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Amgad Mentias Marwan Saad Venu Menon Grant W Reed Zoran Popovic Douglas Johnston Leonardo Rodriguez Marc Gillinov Brian Griffin Hani Jneid Sidakpal Panaich Samir Kapadia Lars G Svensson Milind Y Desai Source Type: research

2023 Alzheimer's disease facts and figures
This article describes the public health impact of Alzheimer's disease, including prevalence and incidence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society. The Special Report examines the patient journey from awareness of cognitive changes to potential treatment with drugs that change the underlying biology of Alzheimer's. An estimated 6.7 million Americans age 65 and older are living with Alzheimer's dementia today. This number could grow to 13.8 million by 2060 barring the development of medical breakthroughs to prevent, slow or cure AD. Off...
Source: The Journal of Alzheimers Association - March 15, 2023 Category: Psychiatry Source Type: research

Recent trends in high-volume Medicare stroke thrombectomy provider characteristics
Conclusions High-volume providers of MT services for Medicare beneficiaries represent a dynamic and rapidly expanding subset of physicians with diverse specialty backgrounds.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Jayaraman, K., Santavicca, S., Hughes, D. R., Hirsch, J. A., Duszak,, R., Chatterjee, A. R. Tags: Socioeconomics Source Type: research

Inequities in Telemedicine Use Among Patients With Stroke and Cerebrovascular Diseases: A Tricenter Cross-sectional Study
Discussion In our diverse cohort across 3 centers, we found differences in TM visit type by race and insurance early during the COVID-19 pandemic. These findings suggest disparities in VTM access across different stroke populations. As VTM remains an integral part of outpatient neurology practice, steps to ensure equitable access are essential.
Source: Neurology Clinical Practice - March 14, 2023 Category: Neurology Authors: Naqvi, I. A., Cohen, A. S., Kim, Y., Harris, J., Denny, M. C., Strobino, K., Bicher, N., Leite, R. A., Sadowsky, D., Adegboye, C., Okpala, N., Okpala, M., Savitz, S. I., Marshall, R. S., Sharrief, A. Tags: All Health Services Research, All Cerebrovascular disease/Stroke, Underserved populations, Health disparities Research Article Source Type: research

Comparison of Unibody and Non-Unibody Endografts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries: The SAFE-AAA Study
CONCLUSIONS: In the SAFE-AAA Study, unibody endografts failed to meet noninferiority compared with non-unibody endografts with respect to aortic reintervention, rupture, and mortality. These data support the urgency of instituting a prospective longitudinal surveillance program for monitoring safety events related to aortic stent grafts.PMID:36866664 | DOI:10.1161/CIRCULATIONAHA.122.062123
Source: Circulation - March 3, 2023 Category: Cardiology Authors: Eric A Secemsky Yang Song Tianyu Sun Carmen Gacchina Johnson Megan Gatski Li Wang Andrew Farb Robert E Lee Aurko Shaw Jiaman Xu Robert W Yeh Source Type: research

Forecasting prevalence and mortality of Alzheimer's disease using the partitioning models
This study uses 5 %-Medicare data (1991-2017) to identify, partition, and forecast age-adjusted prevalence and incidence-based mortality of AD as well as their causal components.METHODS: The core underlying methodology is the partitioning analysis that calculates the relative impact each component has on the overall trend as well as intertemporal changes in the strength and direction of these impacts. B-spline functions estimated for all parameters of partitioning models represent the basis for projections of these parameters in future.RESULTS: Prevalence of AD is predicted to be stable between 2017 and 2028 primarily due ...
Source: Experimental Gerontology - February 26, 2023 Category: Geriatrics Authors: I Akushevich A Yashkin M Kovtun J Kravchenko K Arbeev A I Yashin Source Type: research

Incidence of Statin-Associated Adverse Events in Kidney Transplant Recipients
CONCLUSIONS: Statins appear to be generally well-tolerated in kidney transplant recipients. However, statin use might be associated with slightly higher risk of post-transplant diabetes mellitus, cataract, and rhabdomyolysis.PMID:36800538 | DOI:10.2215/CJN.0000000000000124
Source: Clinical Journal of the American Society of Nephrology : CJASN - February 17, 2023 Category: Urology & Nephrology Authors: Sunjae Bae JiYoon B Ahn Kmd Corey Joseph Ryan Whisler Mark A Schnitzler Krista L Lentine Bernard S Kadosh Dorry L Segev Mara A McAdams-DeMarco Source Type: research