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Total 992 results found since Jan 2013.

Cost of treatment failure: Medicare spending on stroke for atrial fibrillation patients not receiving anticoagulation
It is well known that atrial fibrillation (AF) patients not receiving anticoagulants are at higher risk of Ischemic Stroke (IS).
Source: Journal of the Neurological Sciences - September 19, 2023 Category: Neurology Authors: Steven D. Culler, W. Frank Peacock, April W. Simon Source Type: research

Retrospective cohort study investigating synergism of air pollution and corticosteroid exposure in promoting cardiovascular and thromboembolic events in older adults
Conclusion PM2.5 and systemic corticosteroid use were independently associated with increases in CTE hospitalisations. We also found evidence of significant additive interactions between the two exposures for HF and MI/ACSs suggesting synergy between these two exposures.
Source: BMJ Open - September 13, 2023 Category: General Medicine Authors: Josey, K., Nethery, R., Visaria, A., Bates, B., Gandhi, P., Parthasarathi, A., Rua, M., Robinson, D., Setoguchi, S. Tags: Open access, Epidemiology Source Type: research

Here Are the First 10 Drugs Biden Will Target for Price Negotiations
WASHINGTON (AP) — The popular diabetes treatment Jardiance and the blood thinner Eliquis are among the first drugs that will be targeted for price negotiations in effort to cut Medicare costs. President Joe Biden’s administration on Tuesday released a list of 10 drugs for which the federal government will take a first-ever step: negotiating drug prices directly with the manufacturer. [time-brightcove not-tgx=”true”] The move is expected to cut costs for some patients but faces litigation from the drugmakers and heavy criticism from Republican lawmakers. It’s also a centerpiece of t...
Source: TIME: Health - August 29, 2023 Category: Consumer Health News Authors: TOM MURPHY, AMANDA SEITZ and CHRIS MEGERIAN / AP Tags: Uncategorized wire Source Type: news

Signal detection of adverse events associated with gabapentinoid use for chronic pain
CONCLUSIONS: Our study identified expected and unexpected ADE signals in GABA users. Neurological signals likely related to indications for GABA use. Signals for immunity, mental/behavior, and skin disorders were found in the FDA adverse event reporting system database. Unexpected signals of stroke and cancer require further confirmatory analyses to verify.PMID:37640024 | DOI:10.1002/pds.5685
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Yong-Fang Kuo Efstathia Polychronopoulou Mukaila A Raji Source Type: research

Long-term outcomes of carotid endarterectomy vs transfemoral carotid stenting in a Medicare-matched database
Carotid endarterectomy (CEA) is associated with lower risk of perioperative stroke compared with transfemoral carotid artery stenting (TFCAS) in the treatment of carotid artery stenosis. However, there is discrepancy in data regarding long-term outcomes. We aimed to compare long-term outcomes of CEA vs TFCAS using the Medicare-matched Vascular Quality Initiative Vascular Implant Surveillance and Interventional Outcomes Network database.
Source: Journal of Vascular Surgery - August 25, 2023 Category: Surgery Authors: Kevin S. Yei, Claire Janssen, Nadin Elsayed, Isaac Naazie, Art Sedrakyan, Mahmoud B. Malas Source Type: research

Long-Term Outcomes of Carotid Endarterectomy vs. Transfemoral Carotid Stenting in a Medicare-Matched Database
Carotid endarterectomy is associated with lower risk of perioperative stroke compared to transfemoral carotid artery stenting in the treatment of carotid artery stenosis. However, there is discrepancy in data regarding long-term outcomes. We aimed to compare long-term outcomes of carotid endarterectomy vs transfemoral carotid artery stenting using the Medicare-matched Vascular Quality Initiative Vascular Implant Surveillance and Interventional Outcomes Network database.
Source: Journal of Vascular Surgery - August 25, 2023 Category: Surgery Authors: Kevin S. Yei, Claire Janssen, Nadin Elsayed, Isaac Naazie, Art Sedrakyan, Mahmoud B. Malas Source Type: research

Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers are Associated With Improved Amputation Free Survival in Chronic Limb-threatening Ischemia
In the Heart Outcomes Prevention Evaluation (HOPE) study, investigators found that ramipril was associated with improved survival as well as decreased myocardial infarction (MI) and stroke rates in patients with peripheral arterial disease. Nonetheless, their effect on chronic limb-threatening ischemia (CLTI)-specific outcomes is unclear. We aim to assess the effect of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (ACEIs/ARBs) on amputation-free survival in patients with CLTI undergoing peripheral vascular intervention (PVI) in a Medicare-linked database.
Source: Journal of Vascular Surgery - August 18, 2023 Category: Surgery Authors: Nadin Elsayed, Darrin Clouse, Raghu L. Motaganahalli, Mahmoud Malas Source Type: research

Current Evidence on the Impact of Medicare Payment Policy on Stroke Rehabilitation in Skilled Nursing Facilities
AbstractPurpose of ReviewPatients recovering from stroke benefit from frequent, multi-disciplinary therapies in skilled nursing facilities (SNFs). As a major driver of spending, rehabilitation in SNFs is vulnerable to scrutiny from payers including Medicare. This review explored impacts of current payment programs (Patient Driven Payment Model, Bundled Payments for Care Improvement Advanced, Accountable Care Organizations, and Medicare Advantage) on access and outcomes of rehabilitation in SNFs after stroke.Recent FindingsThere is minimal SNF payment research specific to stroke. For the general Medicare population, payment...
Source: Current Physical Medicine and Rehabilitation Reports - August 18, 2023 Category: Rehabilitation Source Type: research

Unintended Consequences of Increased Out-of-Pocket Costs During Medicare Coverage Gap on Anticoagulant Discontinuation and Stroke
CONCLUSION: Increased OOP costs during Medicare coverage gap were associated with higher risk of DOAC discontinuation, which in turn was associated with higher risk of stroke and SE among beneficiaries with NVAF.PMID:37568060 | DOI:10.1007/s12325-023-02620-z
Source: Adv Data - August 11, 2023 Category: Epidemiology Authors: Tabassum Salam Urvi Desai Patrick Lefebvre E Jian-Yu Alexandra Greatsinger Nina Zacharia Fran çois Laliberté Brahim Bookhart Akshay Kharat Source Type: research

Where You Live Can Shape How Alzheimer ’ s Affects You
The FDA in mid-July for the first time ever approved an Alzheimer’s drug, Leqembi. The annual price-tag will run patients $26,500. The same week, the Alzheimer’s Association for the first time ever released county-level data to identify which communities are most struggling with the disease. 6.7 million Americans live with Alzheimer’s disease and 134,000 of them will die because of it each year. We’ve known these aggregate numbers for a while now, but with new data and new drugs, healthcare specialists can now better target attention and resources. [time-brightcove not-tgx=”true”] ...
Source: TIME: Health - August 7, 2023 Category: Consumer Health News Authors: Jeremy Ney Tags: Uncategorized freelance Source Type: news

Hierarchical Development of Physical Frailty and Cognitive Impairment and Their Association With Incident Cardiovascular Disease
CONCLUSIONS: The simultaneous development of frailty and CI is associated with an increased risk of adverse cardiovascular outcomes including death compared with the development of each syndrome alone. Diagnostics to detect frailty and CI are critical in assessment of cardiovascular risk in the older population.PMID:37538136 | PMC:PMC10399211 | DOI:10.1016/j.jacadv.2023.100318
Source: Adv Data - August 4, 2023 Category: Epidemiology Authors: Abdulla A Damluji Naila Ijaz Shang-En Chung Qian-Li Xue Rani K Hasan Wayne B Batchelor Ariela R Orkaby Ajar Kochar Michael G Nanna David L Roth Jeremy D Walston Jon R Resar Gary Gerstenblith Source Type: research

Association of Plasma A β 42/40 Ratio and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study
DISCUSSION: A reduction in plasma Aβ42/Aβ40 is associated with an increased risk of subsequent epilepsy. Our observations provide a further validation of the link between Aβ, hyperexcitable states, and LOE.PMID:37541842 | DOI:10.1212/WNL.0000000000207635
Source: Atherosclerosis - August 4, 2023 Category: Cardiology Authors: Emily L Johnson Kevin J Sullivan Andrea Lauren Christman Schneider Jeannette Simino Tom H Mosley Anna Kucharska-Newton David S Knopman Rebecca F Gottesman Source Type: research