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Low cholesterol may increase risk for hemorrhagic stroke
LDL cholesterol levels below 70 mg/dL linked to higher risk of haemorrhagic stroke Related items fromOnMedica NICE issues guidelines on neurological conditions Stroke patients still not getting care they need Vitamin D supplements do not confer cardiovascular protection Physical activity might offset harms of time spent sitting Recurrent stroke more likely at very low BP
Source: OnMedica Latest News - July 2, 2019 Category: UK Health Source Type: news

Low cholesterol may increase risk for haemorrhagic stroke
LDL cholesterol levels below 70 mg/dL linked to higher risk of haemorrhagic stroke Related items fromOnMedica NICE issues guidelines on neurological conditions Stroke patients still not getting care they need Vitamin D supplements do not confer cardiovascular protection Physical activity might offset harms of time spent sitting Recurrent stroke more likely at very low BP
Source: OnMedica Latest News - July 2, 2019 Category: UK Health Source Type: news

Losing And Finding My Mother After Her Stroke
The air outside a hospital feels especially cool and fresh. The natural light, even if it's gray January light is a blessed relief after the fluorescent tunnels I've been guiding my mother along. We had a funny moment of intimacy in the bathroom, trying to get her urine sample in a cup. It isn't easy: crouching, aiming, approximating where in the space below you the stream will collect. Add a daughter trying to micromanage her mother's urine flow and a line of weak-bladdered patients queuing outside, rolling their eyes and tugging at their waistbands and you have all the ingredients of a Mike and Elaine sketch. Sometimes...
Source: Healthy Living - The Huffington Post - March 19, 2015 Category: Consumer Health News Source Type: news

The role of interventional neuroradiology in treatment of hemorrhagic stroke.
Abstract Treatment of hemorrhagic strokes necessitates hospitalization in an accommodated hospital offering the possibility of a multidisciplinary approach. In this setting, over recent years interventional radiology has become increasingly important from the diagnostic as well as the therapeutic standpoint. In the context of subarachnoid hemorrhage by intracranial aneurysm rupture, the NICE (National Institute for Health and Clinical Excellence) and ASA (American Stroke Academy) recommendations suggest that endovascular coiling should be considered as an alternative to surgical clipping (class I, level of evidenc...
Source: Presse Medicale - May 29, 2019 Category: General Medicine Authors: Michelozzi C, Cognard C Tags: Presse Med Source Type: research

What is the Price of the Potential for a Meaningful Recovery following Intracerebral Hemorrhage?
In this issue of the Journal of Stroke and Cerebrovascular Diseases, Vardanyan and colleagues report on the cost-utility of minimally invasive surgery (MIS) with thrombolysis for spontaneous intracerebral hemorrhage (ICH) from the perspective of the United Kingdom (UK) National Health Service (NHS)1 using data from the Minimally Invasive Surgery Plus Alteplase in Intracerebral Hemorrhage Evacuation (MISTIE III) trial2 and the UK Sentinel Stroke National Audit Programme (SSNAP).3 The economic evaluation revealed that the incremental cost-effectiveness ratio for MIS with thrombolysis fell significantly above the UK's Nationa...
Source: Journal of Stroke and Cerebrovascular Diseases - July 27, 2021 Category: Neurology Authors: Lourdes R. Carhuapoma, Avni Kapadia, Henry A. Glick, Daniel F. Hanley Source Type: research

Rivaroxaban for Preventing Atherothrombotic Events in People with Acute Coronary Syndrome and Elevated Cardiac Biomarkers: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
Abstract As part of its Single Technology Appraisal process, the National Institute for Health and Care Excellence (NICE) invited the company that manufactures rivaroxaban (Xarelto, Bayer) to submit evidence of the clinical and cost effectiveness of rivaroxaban for the prevention of adverse outcomes in patients after the acute management of acute coronary syndrome (ACS). The School of Health and Related Research Technology Appraisal Group at the University of Sheffield was commissioned to act as the independent Evidence Review Group (ERG). The ERG produced a critical review of the evidence for the clinical and cos...
Source: PharmacoEconomics - December 21, 2015 Category: Health Management Source Type: research

Reply: Septic cerebral emboli as a risk factor for thrombolysis-related haemorrhagic transformation
We appreciate the opportunity to respond to Dr. Jolobe ’s letter titled ‘Septic cerebral emboli as a risk factor for thrombolysis-related hemorrhagic transformation’. Dr. Jolobe made a nice comment on our article titled ‘Risk factors of hemorrhagic transformation after intravenous thrombolysis with rt-PA in acute cerebral infarction’.1 We agree that septic cerebral emboli was a risk factor for thrombolysis-related hemorrhagic transformation as demonstrated in an early study.2 In fact, it was based on this early study and the following studies that intravenous thrombolysis is not recommended for patients with acut...
Source: QJM - January 25, 2019 Category: Internal Medicine Source Type: research

Mr. M
Dr. Migliore I step off the subway, up the elevator, and up several flights of stairs. There’s a homeless man there who always uses the last stair of the lower staircase as a tray for his food. And by tray, I mean he sets his half-eaten rice burrito directly onto the step and picks around at it while I imagine the guacamole is mixing with Hep B and C. diff and MRSA. He looks up at me, I promise myself for the 100th time I’m going to start carrying cash or Kind bars or something; I give him my best sheepish face, and emerge at street level. I walk toward my hospital and pass a gentleman who sits on a ledge next to the ...
Source: The Hospitalist - December 1, 2022 Category: Hospital Management Authors: Lisa Casinger Tags: Essay Source Type: research

Alteplase for the Treatment of Acute Ischaemic Stroke: A NICE Single Technology Appraisal; an Evidence Review Group Perspective
Abstract The National Institute for Health and Care Excellence (NICE) invited Boehringer Ingelheim GmbH, the manufacturer of alteplase, to submit evidence for the clinical and cost-effectiveness of alteplase for the prevention of strokes within a 0–4.5 h window. The comparator was standard medical and supportive management that does not include alteplase. This paper provides a description of the company submission, the Evidence Review Group (ERG) review and NICE's subsequent decisions. Clinical effectiveness evidence for alteplase was derived from 5 trials. For the 3–4.5 h treatment window, alteplase did not...
Source: PharmacoEconomics - November 26, 2014 Category: Health Management Source Type: research

French Intensive Care Society, International congress - Réanimation 2016.
C, Sauneuf B, Verrier P, Pottier V, Orabona M, Samba D, Viquesnel G, Lermuzeaux M, Hazera P, Hanouz JL, Parienti JJ, Du Cheyron D, Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guérin C, Dellamonica J, Jaber S, Similowski T, Quenot JP, Binquet C, Vinsonneau C, Barbar SD, Vinault S, Deckert V, Lemaire S, Hssain AA, Bruyère R, Souweine B, Lagrost L, Adrie C, Jung B, Daurat A, De Jong A, Chanques G, Mahul M, Monnin M, Molinari N, Lheureux O, Trepo E, Hites M, Cotton F, Wolff F, Surin R, Créteur J, Vincent JL, Gustot T, Jacobs F, Taccone FS, Neuville M, Timsit JF, El-Hel...
Source: Australian Family Physician - May 31, 2016 Category: Primary Care Authors: Jaillette E, Girault C, Brunin G, Zerimech F, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Robriquet L, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S, Valette X, Desmeulles I, Savary B, Masson R, Seguin A, Daubi Tags: Ann Intensive Care Source Type: research

Neurosurgical Intensive Care
Neurocritical care as a subspecialty has grown rapidly over the last two decades, including fast-growing new techniques in neuromonitoring, neuroimaging, and various therapeutic tools.Neurosurgical Intensive Care by Javed Siddiqi is a focused, concise handbook that provides a quick review mainly for residents and fellows receiving training in neurocritical care, but also provides a useful refresher for other healthcare professionals providing care to critically ill neurosurgical patients. The book has 31 chapters with some changes in the table of contents and the addition of two chapters compared with the first edition. Ne...
Source: Anesthesiology - January 17, 2018 Category: Anesthesiology Source Type: research

A journey through clinic and research
I started to study Medicine at the University of Genoa, Italy more than 20 years ago and I now realize that I was quite far from understanding what ‘Medicine’ really means. After weeks and weeks spent on books during the first year, I understood that becoming a MD not only requires the willingness to help people with health problems, but also strong motivation and dedication to learn a huge amount of notions. In Italy, as it is the case for several other countries, the University courses last 6 years, during which the MD student is fully engaged by individual study, lessons and seminars, exercises, and internships. Wit...
Source: European Heart Journal - March 29, 2021 Category: Cardiology Source Type: research