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Total 326 results found since Jan 2013.

A cluster-randomized controlled trial of a computerized antithrombotic risk assessment tool to optimize stroke prevention in general practice: a study protocol
This study (a prospective, cluster-randomized controlled clinical trial) will be conducted across selected regions in the state of New South Wales, Australia. Fifty GPs will be randomized to either the 'intervention' or 'control' arm, with each GP recruiting 10 patients (aged>=65 with AF); target sample size is 500 patients. GPs in the intervention arm will use CARAT during routine patient consultations to: assess risk factors for stroke, bleeding and medication misadventure; quantify the risk/benefit ratio of antithrombotic treatment, identify the recommended therapy, and decide on the treatment course, for an individual ...
Source: BMC Health Services Research - February 7, 2014 Category: Journals (General) Authors: Beata BajorekParker MaginSarah HilmerInes Krass Source Type: research

Antiepileptic drugs and the risk of ischaemic stroke and myocardial infarction: a population-based cohort study
Conclusions The use of enzyme-inducing AEDs was not associated with an increased risk of ischaemic stroke; a small increase of MI with prolonged use was observed. In contrast, use of inhibiting AEDs was associated with a decreased risk of MI.
Source: BMJ Open - August 12, 2015 Category: Journals (General) Authors: Renoux, C., Dell'Aniello, S., Saarela, O., Filion, K. B., Boivin, J.-F. Tags: Open access, Cardiovascular medicine, Epidemiology, Neurology, Public health Research Source Type: research

Morning and Evening Home Blood Pressure and Risks of Incident Stroke and Coronary Artery Disease in the Japanese General Practice Population: The Japan Morning Surge-Home Blood Pressure Study Epidemiology/Population
Our aim is to determine the optimal time schedule for home blood pressure (BP) monitoring that best predicts stroke and coronary artery disease in general practice. The Japan Morning Surge-Home Blood Pressure (J-HOP) study is a nationwide practice-based study that included 4310 Japanese with a history of or risk factors for cardiovascular disease, or both (mean age, 65 years; 79% used antihypertensive medication). Home BP measures were taken twice daily (morning and evening) over 14 days at baseline. During a mean follow-up of 4 years (16 929 person-years), 74 stroke and 77 coronary artery disease events occurred. Morning ...
Source: Hypertension - June 7, 2016 Category: Cardiology Authors: Hoshide, S., Yano, Y., Haimoto, H., Yamagiwa, K., Uchiba, K., Nagasaka, S., Matsui, Y., Nakamura, A., Fukutomi, M., Eguchi, K., Ishikawa, J., Kario, K., on behalf of the J-HOP Study Group Tags: Hypertension Epidemiology/Population Source Type: research

Utilization of antithrombotic therapy for stroke prevention in atrial fibrillation: a cross‐sectional baseline analysis in general practice
Conclusion: We found an encouraging improvement compared to previous studies in the utilisation of antithrombotic therapy for stroke prevention in AF within general practice. Warfarin is now utilised as the mainstay therapy, followed by aspirin, although the novel oral anticoagulants are entering the spectrum of therapies used. Consideration needs to be given to the potential impact of the newer agents and their scope of use. There has been an encouraging temporal improvement in the utilization of antithrombotic therapy for stroke prevention in AF within general practice. Anticoagulants (mostly warfarin) are now utilized ...
Source: Journal of Clinical Pharmacy and Therapeutics - June 23, 2016 Category: Drugs & Pharmacology Authors: B. Bajorek, P. J. Magin, S. Hilmer, I. Krass Tags: Original Article Source Type: research

Utilization of antithrombotic therapy for stroke prevention in atrial fibrillation: a cross ‐sectional baseline analysis in general practice
Conclusion: We found an encouraging improvement compared to previous studies in the utilisation of antithrombotic therapy for stroke prevention in AF within general practice. Warfarin is now utilised as the mainstay therapy, followed by aspirin, although the novel oral anticoagulants are entering the spectrum of therapies used. Consideration needs to be given to the potential impact of the newer agents and their scope of use. There has been an encouraging temporal improvement in the utilization of antithrombotic therapy for stroke prevention in AF within general practice. Anticoagulants (mostly warfarin) are now utilized ...
Source: Journal of Clinical Pharmacy and Therapeutics - June 23, 2016 Category: Drugs & Pharmacology Authors: B. Bajorek, P. J. Magin, S. Hilmer, I. Krass Tags: Original Article Source Type: research

Potential impact of new oral anticoagulants on the management of atrial fibrillation‐related stroke in primary care
ConclusionThe clinical and economic benefits of the new oral anticoagulants, along with appropriate risk stratification, may enable a higher number of patients with AF to receive effective and convenient prophylaxis for stroke prevention.
Source: International Journal of Clinical Practice - April 28, 2013 Category: Internal Medicine Authors: K. Harris, J. Mant Tags: Review Article Source Type: research

AUtomated Risk Assessment for Stroke in Atrial Fibrillation (AURAS-AF) - an automated software system to promote anticoagulation and reduce stroke risk: study protocol for a cluster randomised controlled trial
DiscussionAURAS-AF will investigate whether a simple intervention, using electronic primary care records, can improve OAC uptake in a high risk group for stroke. Given previous concerns about safety, especially surrounding inappropriate prescribing, we will also examine whether electronic reminders safely impact care in this clinical area.Trial registration: ISRCTN 55722437
Source: Trials - November 13, 2013 Category: Journals (General) Authors: Tim HoltDavid FitzmauriceTom MarshallMatthew FayNadeem QureshiAndrew DaltonF HobbsDaniel LassersonKaren KearleyJenny HislopJing Jin Source Type: research

Stroke.
Abstract In 2012, about 50 000 Australians had a stroke (cerebrovascular accident (CVA)). The risk of stroke is associated with increased age, previous stroke or transient ischaemic attack, hypertension, smoking, diabetes mellitus (DM), hypercholesterolaemia and atrial fibrillation/flutter (AF). Australian general practice data from the national BEACH program between April 2000 and March 2013 inclusive (1 276 200 GP-patient encounters) were analysed to determine the patient characteristics, associated conditions and management options at those encounters where a CVA was recorded, and detect changes in the annual m...
Source: Australian Family Physician - March 1, 2014 Category: Primary Care Authors: Pollack A, Harrison C, Henderson J, Miller G Tags: Aust Fam Physician Source Type: research

'BeAWARE': supporting non-clinical staff within general practice to promptly identify patients presenting with warning signs of heart attack or stroke.
DISCUSSION: BeAWARE fulfils a practice gap in patient safety by improving non-clinical staff's knowledge, confidence and intended action in response to patients presenting with heart attack or stroke warning signs. PMID: 24897991 [PubMed - in process]
Source: Australian Family Physician - June 1, 2014 Category: Primary Care Authors: Poulter C, Stewart M, Fitzpatrick C, Keech W, Stavreski B, Grenfell R Tags: Aust Fam Physician Source Type: research

Effectiveness of a shared team approach between nurses and doctors for improved risk factor management in survivors of stroke: a cluster randomized controlled trial
ConclusionsThe effectiveness of an organized secondary prevention programme for stroke may be limited in patients from high‐performing hospitals with regular post‐discharge follow‐up and communication with general practices.
Source: European Journal of Neurology - May 1, 2017 Category: Neurology Authors: M. T. Olaiya, J. Kim, M. R. Nelson, V. K. Srikanth, C. F. Bladin, R. P. Gerraty, S. M. Fitzgerald, T. Phan, J. Frayne, D. A. Cadilhac, A. G. Thrift, Tags: Original Article Source Type: research

Barriers to a software reminder system for risk assessment of stroke in atrial fibrillation: a process evaluation of a cluster randomised trial in general practice.
CONCLUSION: Automated risk assessment for stroke in atrial fibrillation and prompting during consultations are feasible and generally acceptable, but did not overcome concerns about frailty and risk of haemorrhage as barriers to anticoagulant uptake. PMID: 30397015 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - November 5, 2018 Category: Primary Care Authors: Holt TA, Dalton AR, Kirkpatrick S, Hislop J, Marshall T, Fay M, Qureshi N, Lasserson DS, Kearley K, Mollison J, Yu LM, Fitzmaurice D, Hobbs FR Tags: Br J Gen Pract Source Type: research

The Characteristics of Patients With Possible Transient Ischemic Attack and Minor Stroke in the Hunter and Manning Valley Regions, Australia (the INSIST Study)
Conclusion: This study provides the first contemporary data on TIAMS or TIAMS-mimics in Australia. Community and health provider education is required to address the under-use of anticoagulation therapy in patients with known AF, possibly inappropriate use of antiplatelet therapy and possibly inappropriate discontinuation of antiplatelet or anticoagulation therapy.
Source: Frontiers in Neurology - May 14, 2020 Category: Neurology Source Type: research

Prescription of oral anticoagulants and antiplatelets for stroke prophylaxis in atrial fibrillation: nationwide time series ecological analysis
ConclusionBetween 2009 and 2018, in England, the use of OAC for stroke prophylaxis in AF increased, with DOAC accounting for over half of OAC uptake in 2018. Despite a reduction in the OAC-prescription gap, a new paradox exists relating to DOAC prescription for the elderly and those at higher risk of stroke.
Source: Europace - August 10, 2020 Category: Cardiology Source Type: research

Predicting the risk of stroke in patients with late-onset epilepsy: A machine learning approach
CONCLUSION: The stroke risk in patients with epilepsy was relatively high and could be predicted based on comorbidities such as diabetes mellitus, hypertension, heart failure, and alcohol dependence. Knowing and addressing these factors may help reduce the risk of stroke in patients with epilepsy.PMID:34325155 | DOI:10.1016/j.yebeh.2021.108211
Source: Epilepsy and Behaviour - July 29, 2021 Category: Neurology Authors: Karel Kostev Tong Wu Yue Wang Kal Chaudhuri Christian Tanislav Source Type: research