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Total 326 results found since Jan 2013.

Guideline Adherence of Antithrombotic Treatment Initiated by General Practitioners in Patients With Nonvalvular Atrial Fibrillation: A Danish Survey
ConclusionsAntithrombotic treatment of AF patients is in general well performed in primary care in Denmark. Further improvements may be achieved by thorough stroke risk stratification on the basis of current evidence‐based guidelines.
Source: Clinical Cardiology - May 13, 2013 Category: Cardiology Authors: Axel Brandes, Mikkel Overgaard, Liane Plauborg, Christian Dehlendorff, Frede Lyck, Jørgen Peulicke, Søren Vinther Poulsen, Steen Husted Tags: Clinical Investigation Source Type: research

The inter-contact interval: a new measure to define frequent attenders in primary care
Background: Frequent attenders receive much attention in primary care research. Defining frequent attendance is crucial for an adequate view on this group of demanding patients. We aimed to develop a purely contact-based definition of "frequent attendance" and to apply it to real patients. Methods: From electronic records of 123 general practices in Germany, patients' inter-contact intervals (ICI) between two consecutive doctor-patient-contacts were calculated in this retrospective observational study. ICI less than 7 days were labelled "frequent attendance", patients with 60% or more of such intervals "frequent attenders ...
Source: BMC Family Practice - October 23, 2013 Category: Primary Care Authors: Johannes HauswaldtWolfgang HimmelEva Hummers-Pradier Source Type: research

Adjusting for measurement error in baseline prognostic biomarkers included in a time-to-event analysis: a joint modelling approach
Conclusion: The joint modelling of longitudinal and survival data is a valid approach to account for measurement error in the analysis of a repeatedly measured biomarker and a time-to-event. User friendly Stata software is provided.
Source: BMC Medical Research Methodology - Latest articles - December 1, 2013 Category: Research Authors: Michael CrowtherPaul LambertKeith Abrams Source Type: research

Cardiovascular, Bleeding, and Mortality Risks in Elderly Medicare Patients Treated with Dabigatran or Warfarin for Non-Valvular Atrial Fibrillation.
CONCLUSIONS: -In general practice settings, dabigatran was associated with reduced risk of ischemic stroke, intracranial hemorrhage, and death, and increased risk of major gastrointestinal hemorrhage compared with warfarin in elderly patients with non-valvular AF. These associations were most pronounced in patients treated with dabigatran 150 mg twice daily, whereas the association of 75 mg twice daily with study outcomes was indistinguishable from warfarin except for a lower risk of intracranial hemorrhage with dabigatran. PMID: 25359164 [PubMed - as supplied by publisher]
Source: Circulation - October 30, 2014 Category: Cardiology Authors: Graham DJ, Reichman ME, Wernecke M, Zhang R, Southworth MR, Levenson M, Sheu TC, Mott K, Goulding MR, Houstoun M, MaCurdy TE, Worrall C, Kelman JA Tags: Circulation Source Type: research

Association of self-rated health with multimorbidity, chronic disease and psychosocial factors in a large middle-aged and older cohort from general practice: a cross-sectional study
Conclusions: Self-rated health provides a simple, integrative patient-centred assessment for evaluation of illness in the context of multiple chronic disease diagnoses. Those registering in general practice in particular men with three or more diseases or those with cardiovascular comorbidities and with poorer self-rated health may warrant further assessment and intervention to improve their physical and subjective health.
Source: BMC Family Practice - November 25, 2014 Category: Primary Care Authors: Nahal MavaddatJose ValderasRianne van der LindeKay KhawAnn Kinmonth Source Type: research

The impact of patients' involvement in cooking on their mortality and morbidity: A 19-year follow-up of patients diagnosed with type 2 diabetes mellitus.
Conclusions. In patients newly diagnosed with T2DM and with a regular intake of warm main meals, infrequent involvement in cooking was associated with an increased risk of diabetes-related death and stroke for women, but not for men. General practitioners should pay special attention to managing diabetes treatment in female patients newly diagnosed with T2DM who report infrequent involvement in cooking. PMID: 25592166 [PubMed - as supplied by publisher]
Source: Primary Care - January 16, 2015 Category: Primary Care Authors: Jandorf S, Siersma V, Køster-Rasmussen R, Olivarius NF, Waldorff FB Tags: Scand J Prim Health Care Source Type: research

A retrospective cohort study to investigate fatigue, psychological or cognitive impairment after TIA: protocol paper
Introduction Transient ischaemic attack (TIA) is defined by short-lasting, stroke-like symptoms, and is recognised as a medical emergency. Symptoms are assumed to completely resolve, and treatment is focused on secondary stroke/TIA prevention. However, evidence suggests that patients with TIA may experience ongoing residual impairments, which they do not receive therapy for as standard practice. TIA-induced sequelae could impact on patients’ quality of life and ability to return to work or social activities. We aim to investigate whether TIA is associated with subsequent consultation for fatigue, psychological or cog...
Source: BMJ Open - May 3, 2015 Category: Journals (General) Authors: Moran, G. M., Calvert, M., Feltham, M. G., Ryan, R., Marshall, T. Tags: Open access, Cardiovascular medicine, Epidemiology, General practice / Family practice Protocol Source Type: research

Mortality and cardiovascular disease outcomes among 740 patients with new‐onset Type 2 diabetes detected by screening or clinically diagnosed in general practice
ConclusionsNo reduction in total mortality or CVD outcomes was found in patients with Type 2 diabetes that was detected by screening compared with those diagnosed clinically.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - October 30, 2015 Category: Endocrinology Authors: S. P. O. Jansson, D. K. G. Andersson, K. Svärdsudd Tags: Research Article Source Type: research

New oral anticoagulants for nonvalvular atrial fibrillation in the elderly: Limited applicability in primary care.
CONCLUSION: There is uncertainty about effectiveness and safety of NOACs in unselected elderly patients with AF in primary care. Therefore, the balance between benefit and harm is still unclear. For this reason, routine use of NOACs is not recommended in elderly patients in primary care. PMID: 25495417 [PubMed - in process]
Source: European Journal of General Practice - December 4, 2015 Category: Primary Care Tags: Eur J Gen Pract Source Type: research

Prevalence of chronic diseases among older patients in German general practices.
CONCLUSIONS: Our study showed that the prevalence of CDs is high in the German elderly population. Hypertension was the most frequent chronic condition and around 25% of patients displayed at least four CDs. PMID: 26977142 [PubMed - in process]
Source: GMS German Medical Science - March 17, 2016 Category: Journals (General) Tags: Ger Med Sci Source Type: research

Renal function and attributable risk of death and cardiovascular hospitalization in patients with cardiovascular risk factors from a registry-based cohort: the Estudio Cardiovascular Valencia-risk study
Conclusion: In a large general practice cohort of patients with cardiovascular disease risk factors, decreasing eGFR levels were associated with additional attributed risk of mortality and cardiovascular disease. Our findings underscore that intensified efforts are needed to reduce the cardiovascular disease burden associated to chronic kidney disease.
Source: Journal of Hypertension - September 30, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research

The involvement of pharmacies in the screening of undiagnosed atrial fibrillation
AbstractEarly identification of atrial fibrillation (AF) is now a priority in cardiovascular prevention because AF is common although often asymptomatic, and is associated with poor outcomes that are highly preventable with appropriate medical treatment. In Italy, AF prevalence among subjects aged ≥65 years ranges from 5 to 6% in observational studies based on the diagnosis recorded by general practitioners to 10–11% in studies where ECG screening is routinely offered. It is thus evident that a large number of subjects are not detected by conventional approach, and new strategies are req uired to increase early detect...
Source: Internal and Emergency Medicine - September 19, 2017 Category: Emergency Medicine Source Type: research

Burden of cardiovascular disease across 29 countries and GPs' decision to treat hypertension in oldest-old.
CONCLUSIONS: GPs' choice to treat/not treat hypertension in oldest-old was explained by differences in country-specific health characteristics. GPs in countries with high CVD burden and low life expectancy at age 60 were most likely to treat hypertension in oldest-old. Key Points  • General practitioners (GPs) are in a clinical dilemma when deciding whether (or not) to treat hypertension in the oldest-old (>80 years of age).  • In this study including 1947 GPs from 29 countries, we found that a high country-specific cardiovascular disease (CVD) burden (i.e. myocardial infarction and/or stroke) was associated...
Source: Primary Care - January 25, 2018 Category: Primary Care Authors: Streit S, Gussekloo J, Burman RA, Collins C, Kitanovska BG, Gintere S, Gómez Bravo R, Hoffmann K, Iftode C, Johansen KL, Kerse N, Koskela TH, Peštić SK, Kurpas D, Mallen CD, Maisonneuve H, Merlo C, Mueller Y, Muth C, Ornelas RH, Šter MP, Petrazzuoli F Tags: Scand J Prim Health Care Source Type: research

Opportunistic pulse checks in primary care to improve recognition of atrial fibrillation: a retrospective analysis of electronic patient records.
CONCLUSION: Organisational alignment, standardised data entry, peer-performance dashboards, and financial incentives rapidly and generally increased opportunistic screening with pulse regularity checks. This was associated with a significant increase in detection and prevalence of AF and is of public health importance. PMID: 29784865 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - May 21, 2018 Category: Primary Care Authors: Cole J, Torabi P, Dostal I, Homer K, Robson J Tags: Br J Gen Pract Source Type: research

GPs' management of polypharmacy and therapeutic dilemma in patients with multimorbidity: a cross-sectional survey of GPs in France.
CONCLUSION: In therapeutic dilemmas, some GPs choose to prioritise patients' requests over iatrogenic risks. GPs need pragmatic implementation tools for handling therapeutic dilemmas, and to improve their skills in medication management and patient engagement in such situations. PMID: 30803978 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - February 25, 2019 Category: Primary Care Authors: Carrier H, Zaytseva A, Bocquier A, Villani P, Verdoux H, Fortin M, Verger P Tags: Br J Gen Pract Source Type: research