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Total 326 results found since Jan 2013.

Burden of Atrial Fibrillation in M āori and Pacific People in New Zealand: A Cohort Study
ConclusionAF screening and stroke thromboprophylaxis in Māori and Pacific people could start below the age of 65 years in NZ.
Source: Internal Medicine Journal - October 16, 2017 Category: Internal Medicine Authors: Yulong Gu, Robert N Doughty, Ben Freedman, John Kennelly, Jim Warren, Matire Harwood, Richard Hulme, Chris Paltridge, Ruth Teh, Anna Rolleston, Natalie Walker Tags: Original Article Source Type: research

A reverse J-shaped association between serum 25-hydroxyvitamin D and cardiovascular disease mortality - the CopD-study.
CONCLUSIONS: In this large observational study low and high levels of 25-hydroxyvitamin D were associated with cardiovascular disease, stroke and acute myocardial mortality in a non-linear, reverse J-shaped manner, with highest risk at lower levels. Whether this was a causal or associational finding cannot be determined from our data. There is a need for randomized clinical trials which include information on the effects of 25-hydroxyvitamin D levels above 100 nmol/L. PMID: 25710567 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - February 24, 2015 Category: Endocrinology Authors: Durup D, Jørgensen HL, Christensen J, Tjønneland A, Olsen A, Halkjær J, Lind B, Heegaard AM, Schwarz P Tags: J Clin Endocrinol Metab Source Type: research

Ten-Year Trends in the Use of Oral Anticoagulants in Australian General Practice Patients With Atrial Fibrillation
Conclusions: Over the 10 years, OAC prescribing in high stroke risk patients with AF increased by one-third. There was considerable variation in OAC prescribing between general practices.
Source: Frontiers in Pharmacology - March 23, 2021 Category: Drugs & Pharmacology Source Type: research

RApid Primary care Initiation of Drug treatment for Transient Ischaemic Attack (RAPID-TIA): study protocol for a pilot randomised controlled trial
DiscussionThis pilot study will be used to estimate key parameters that are needed to design the main study and to estimate the accuracy of primary care diagnosis of TIA. The planned follow-on trial will have important implications for the initial management of people with suspected TIA.Trial registration: ISRCTN62019087
Source: Trials - July 2, 2013 Category: Journals (General) Authors: Duncan EdwardsKate FletcherRachel DellerRichard McManusDaniel LassersonMatthew GilesDon SimsJohn NorrieGraham McGuireSimon CohnFiona WhittleVicky HobbsChristopher WeirJonathan Mant Source Type: research

Patients' responses to transient ischaemic attack symptoms: a cross-sectional questionnaire study in Australian general practices.
CONCLUSION: Most general practice attendees expressed intentions to seek health care urgently for most symptoms suggestive of TIA, with highest levels of urgency observed in high stroke-risk scenarios. Intentions were not associated with a number of major risk factors for TIA and might be improved by further educational interventions, either targeted or at population level. PMID: 25548313 [PubMed - in process]
Source: The British Journal of General Practice - January 1, 2015 Category: Primary Care Authors: Magin P, Dunbabin J, Goode S, Valderas JM, Levi C, D'Souza M, Marshall M, Barker D, Lasserson D Tags: Br J Gen Pract Source Type: research

Screening of older patients for atrial fibrillation in general practice: Current evidence and its implications for future practice.
CONCLUSIONS: It was determined that improved detection and diagnosis of AF, combined with appropriate anticoagulation strategies, will be crucial for improving stroke prevention and reducing its associated social and economic costs. PMID: 29034749 [PubMed - in process]
Source: European Journal of General Practice - October 18, 2017 Category: Primary Care Tags: Eur J Gen Pract Source Type: research

Atrial fibrillation and oral anticoagulation in older people with frailty: a nationwide primary care electronic health records cohort study
ConclusionAmong older people in England, AF and stroke risk increased with increasing degree of frailty; however, OAC prescription approximated 50%. Given competing demands of mortality, morbidity and stroke prevention, greater attention to stratified stroke prevention is needed for this group of the population.
Source: Age and Ageing - December 16, 2020 Category: Geriatrics Source Type: research

Two-year outcomes of UK patients newly diagnosed with atrial fibrillation: findings from the prospective observational cohort study GARFIELD-AF
CONCLUSION: The data support a benefit of anticoagulation in reducing stroke and death, without an increased risk of a major bleed in patients with new-onset AF. Anticoagulation treatment in patients at high risk of stroke who are not receiving anticoagulation may further improve outcomes.PMID:35577587 | DOI:10.3399/BJGP.2021.0548
Source: The British Journal of General Practice - May 16, 2022 Category: Primary Care Authors: Patricia N Apenteng Saverio Virdone Fd Richard Hobbs A John Camm Keith Aa Fox Karen S Pieper Gloria Kayani David Fitzmaurice GARFIELD UK investigators* Source Type: research

Using primary care data to assess comparative effectiveness and safety of apixaban and rivaroxaban in patients with nonvalvular atrial fibrillation in the UK: an observational cohort study
Conclusions Among patients with nonvalvular AFib, apixaban was as effective as rivaroxaban in reducing rate of stroke and safer in terms of major bleeding episodes. This head-to-head comparison supports conclusions drawn from indirect comparisons of DOAC trials against warfarin and demonstrates the potential for real-world evidence to fill evidence gaps and reduce uncertainty in both health technology assessment decision-making and clinical guideline development.
Source: BMJ Open - October 17, 2022 Category: General Medicine Authors: Jaksa, A., Gibbs, L., Kent, S., Rowark, S., Duffield, S., Sharma, M., Kincaid, L., Ali, A. K., Patrick, A. R., Govil, P., Jonsson, P., Gatto, N. Tags: Open access, Cardiovascular medicine Source Type: research

'More adults should be taking statins,' says NICE
Conclusion Despite somewhat hysterical media coverage to the contrary ("millions more to be given statins," according to the Daily Express), nobody will be forced to take statins. If your GP does recommend statins, you should ask them to explain the benefits and risks for you personally of starting statin treatment. You may want to find out more about statins before making up your mind – the NHS Choices Health A-Z information on statins is a good place to start. If you do experience troublesome side effects while taking statins, contact your GP or the doctor in charge of your care. It could be the case that a...
Source: NHS News Feed - July 18, 2014 Category: Consumer Health News Tags: Heart/lungs Medication QA articles Source Type: news