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Total 979 results found since Jan 2013.

Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke
CONCLUSIONS: In selected patients with acute ischaemic wake-up stroke, both intravenous thrombolytic treatment and endovascular thrombectomy of large vessel occlusion improved functional outcome without increasing the risk of death. However, a possible increased risk of symptomatic intracranial haemorrhage associated with thrombolytic treatment cannot be ruled out. The criteria used for selecting patients to treatment differed between the trials. All studies were relatively small, and six of the seven studies were terminated early. More studies are warranted in order to determine the optimal criteria for selecting patients...
Source: Cochrane Database of Systematic Reviews - December 1, 2021 Category: General Medicine Authors: Melinda B Roaldsen Haakon Lindekleiv Ellisiv B Mathiesen Source Type: research

Information provision for stroke survivors and their carers
CONCLUSIONS: Active information provision may improve stroke-survivor knowledge and quality of life, and may reduce anxiety and depression. However, the reductions in anxiety and depression scores were small and may not be important. In contrast, providing information passively may slightly worsen stroke-survivor anxiety and depression scores, although again the importance of this is unclear. Evidence relating to carers and to other outcomes of passive information provision is generally very uncertain. Although the best way to provide information is still unclear, the evidence is better for strategies that actively involve...
Source: Cochrane Database of Systematic Reviews - November 23, 2021 Category: General Medicine Authors: Thomas F Crocker Lesley Brown Natalie Lam Faye Wray Peter Knapp Anne Forster Source Type: research

Renal denervation for resistant hypertension
CONCLUSIONS: In patients with resistant hypertension, there is low-certainty evidence that renal denervation does not improve major cardiovascular outomes and renal function. Conversely, moderate-certainty evidence exists that it may improve 24h ABPM and diastolic office-measured BP. Future trials measuring patient-centred instead of surrogate outcomes, with longer follow-up periods, larger sample size and more standardised procedural methods are necessary to clarify the utility of this procedure in this population.PMID:34806762 | DOI:10.1002/14651858.CD011499.pub3
Source: Cochrane Database of Systematic Reviews - November 22, 2021 Category: General Medicine Authors: Anna Pisano Luigi Francesco Iannone Antonio Leo Emilio Russo Giuseppe Coppolino Davide Bolignano Source Type: research

Effect of programmed nursing combined with cognitive behavioral intervention on clinical nursing effect and neurological function of patients with intracerebral hemorrhage
CONCLUSION: Programmed nursing combined with cognitive behavioral intervention can improve the clinical efficacy of patients with ICH, improve limb motor ability, and reduce neurological deficits, with high safety.PMID:34786100 | PMC:PMC8581945
Source: American Journal of Translational Research - November 17, 2021 Category: Research Authors: Xiuqin Wang Xiaoyan Wang Hui Bai Yingxue Zhang Junzeng Si Source Type: research