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Specialty: Neurology
Infectious Disease: Herpes

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Total 75 results found since Jan 2013.

Disseminated cutaneous herpes zoster and multiple cerebral infarcts in an adult with diabetes mellitus
We present the case of a patient with a medical history of type 2 diabetes mellitus (DM) who experienced disseminated cutaneous VZV infection followed by multiple cerebral infarcts associated with VZV vasculopathy. Brain magnetic resonance imaging revealed multiple hyperintense lesions over the bilateral deep white matter and basal ganglia. A skin biopsy revealed small-vessel leukocytoclastic vasculitis with neutrophilic, lymphocytic, and eosinophilic infiltration. This case report describes the rare finding of cutaneous leukocytoclastic vasculitis in VZV infection and highlights that VZV infection is an uncommon but criti...
Source: Journal of NeuroVirology - January 14, 2020 Category: Neurology Source Type: research

Adult onset MELAS Syndrome Presenting as A Mimic of Herpes Simplex Encephalitis.
CONCLUSION: The clinical presentation and imaging studies of MELAS in adults are variable and may mimic those of HSE. Antiviral therapy should be administered until the diagnosis of MELAS is definitive. Infection and metformin may have also precipitated MELAS manifestation in this patient. Clinicians should avoid potential mitochondrial-toxic drugs in these patients. PMID: 31867706 [PubMed - in process]
Source: Acta Neurologica Taiwanica - December 25, 2019 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Bihemisphere Ischemia Due to a Unilateral Lesion: A Case Report
We present the case of a 70-year-old man with multiple acute/subacute bilateral infarcts. The patient was found to have stenosis of the left internal carotid artery secondary to herpes zoster ophthalmicus vasculopathy, with involvement of the left proximal middle and anterior cerebral arteries. Angiographic studies also revealed A1 segment aplasia of the right anterior cerebral artery (ACA), thus indicating dependence on the left-sided circulation for perfusion of the bilateral ACA vascular territory.
Source: Journal of Stroke and Cerebrovascular Diseases - December 24, 2019 Category: Neurology Authors: Lara C. Wadi, Stephen Nnodim, Jeremiah Pack, Mark J. Fisher Tags: Case Report Source Type: research

Cerebrovascular events after herpes zoster infection: a risk that should be not underestimated
AbstractThe occurrence of a cerebrovascular event after a herpes zoster (HZ) infection represents a nightmare in clinical practice, especially in those patients with concomitant cardiovascular comorbidities/risk factors and disease related per se to a higher risk of zoster infection. Moreover, the absence of a consensus opinion regarding a specific and adequate prevention of cerebrovascular events in these patients further complicates the treatment. Accumulating evidences demonstrated that HZ and HZ ophtalmicus (HZO) increase the risk of cerebrovascular events in the short-and long-term periods. Moreover, patient ’s ages...
Source: Journal of NeuroVirology - May 7, 2019 Category: Neurology Source Type: research

Late-onset Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes Presenting With Auditory Agnosia
Conclusions: MELAS is a disorder with clinical variability. Neuroimaging studies during stroke-like episodes in MELAS can provide significant clues to the underlying disorder. Although patients typically present in childhood, the first stroke-like episode can occur later in life in some patients, potentially related to a lower heteroplasmy level.
Source: The Neurologist - May 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research

Cerebrovascular manifestations of herpes simplex virus infection of the central nervous system: a systematic review
Intracerebral hemorrhage and ischemic stroke are increasingly recognized complications of central nervous system (CNS) infection by herpes simplex virus (HSV).
Source: Journal of Neuroinflammation - January 29, 2019 Category: Neurology Authors: Larissa Hauer, Slaven Pikija, Eva C. Schulte, Laszlo K. Sztriha, Raffaele Nardone and Johann Sellner Tags: Research Source Type: research

Clinical presentation, management, and pathophysiology of neuropathic itch
Publication date: August 2018Source: The Lancet Neurology, Volume 17, Issue 8Author(s): Martin Steinhoff, Martin Schmelz, Imre Lőrinc Szabó, Anne Louise OaklanderSummaryUnlike conventional itch, neuropathic itch develops in normal skin from excess peripheral firing or dampened central inhibition of itch pathway neurons. Neuropathic itch is a symptom of the same central and peripheral nervous system disorders that cause neuropathic pain, such as sensory polyneuropathy, radiculopathy, herpes zoster, stroke, or multiple sclerosis, and lesion location affects symptoms more than aetiology. The causes of neuropathic itch are h...
Source: The Lancet Neurology - July 18, 2018 Category: Neurology Source Type: research

Herpes Zoster Is Associated with an Elevated Risk for Stroke and Myocardial Infarction
No abstract available
Source: Neurology Today - August 3, 2017 Category: Neurology Tags: Features Source Type: research

Burden of herpes simplex virus encephalitis in the United States
AbstractHerpes simplex virus encephalitis (HSVE) is a disease of public health concern, but its burden on the healthcare of United States has not been adequately assessed recently. We aimed to define the incidence, complications and outcomes of HSVE in the recent decade by analyzing data from a nationally representative database. Healthcare Cost and Utilization Project databases were utilized to identify patients with primary discharge diagnosis of HSVE. Annual hospitalization rate was estimated and several preselected inpatient complications were identified. Regression analyses were used to identify mortality predictors. ...
Source: Journal of Neurology - May 17, 2017 Category: Neurology Source Type: research

Risk of Stroke/Transient Ischemic Attack or Myocardial Infarction with Herpes Zoster: A Systematic Review and Meta-Analysis
Accumulating evidence indicates that herpes zoster (HZ) may increase the risk of stroke/transient ischemic attack (TIA) or myocardial infarction (MI), but the results are inconsistent. We aim to explore the relationship between HZ and risk of stroke/TIA or MI and between herpes zoster ophthalmicus (HZO) and stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2017 Category: Neurology Authors: Yanting Zhang, Ganfeng Luo, Yuanwei Huang, Qiuyan Yu, Li Wang, Ke Li Source Type: research

Misdiagnosis of CADASIL: A single Medical Center experience (P1.251)
Conclusions:CADASIL is the most prevalent monogenic cerebral small-vessel arteriopathy. Despite wide availability of genetic testing, misdiagnosis and delay diagnosis are common. We encourage for enhanced awareness of CADASIL among patients with migraines with aura, recurrent TIAs or subcortical ischemic strokes, and mood disorder, in order to provide appropriate multidisciplinary treatment, psychological support and genetic counselingStudy Supported by: n/aDisclosure: Dr. Ortiz-Garcia has nothing to disclose. Dr. Orjuela has nothing to disclose. Dr. Sweis has nothing to disclose. Dr. Biller has received personal compensat...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ortiz-Garcia, J., Orjuela, K., Sweis, R., Biller, J. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Stroke Associated With Varicella Zoster Vasculopathy: A Clinicoradiological Profile of 3 Patients
Conclusions: VZ associated vasculopathy may have diverse clinical profile and neuroimaging features. It should be considered as an important and treatable cause of stroke in appropriate clinical settings.
Source: The Neurologist - March 1, 2017 Category: Neurology Tags: Case Report/Case Series Source Type: research

Risk of Stroke in Patients with Herpes Zoster: A Systematic Review and Meta-Analysis
Several observational studies suggest that herpes zoster (HZ) may increase the risk of stroke, but the results are inconsistent. Our study was designed to assess the association between HZ and the risk of stroke through a meta-analysis of cohort studies.
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2016 Category: Neurology Authors: Sheng-Ye Yang, Hong-Xing Li, Xin-Hao Yi, Guang-Liang Han, Qiang Zong, Ming-Xing Wang, Xiao-Xiao Peng Source Type: research

Oculomotor Nerve Palsy after Herpes Zoster Opthalmicus: A Case Report and Review of Literature (P1.297)
Conclusions: HZO is manifestation of re-activation of herpes zoster with involvement of ophthalmic division of trigeminal nerve. CNIII palsy after HZO is rare, especially with associated pupillary defect. The long term prognosis is felt to be excellent with use of antiviral agents and steroids.Disclosure: Dr. Shaker has nothing to disclose. Dr. Rai has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Shaker, H., Rai, V. Tags: Herpes Virus Infections Source Type: research

Ice Pick Headache
Abstract Ice pick headache, also called idiopathic or primary stabbing headache, is a unique headache type associated with ultra-brief stabs of pain, most commonly in the frontal or temporal area. It occurs predominantly in women and is estimated to affect 2–35 % of the population. Unlike other headache types of short duration, such as short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT), ice pick headache is not associated with any cranial autonomic symptoms but has been known to occur with nausea, vomiting, photophobia, and dizziness. It exists in two forms: primary ...
Source: Current Pain and Headache Reports - April 1, 2016 Category: Neurology Source Type: research