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Infectious Disease: COVID-19

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Reductions in Hospital Admissions and Delays in Acute Stroke Care During the Pandemic of COVID-19
Conclusions: Profound reductions in stroke hospital admissions and significant delays in emergency care for acute ischemic stroke occurred during the pandemic of COVID-19. Engagement and effective communication with all stakeholders including patients, health care providers, governmental policymakers, and other implementation partners are required for future success in similar crises.
Source: Frontiers in Neurology - November 5, 2020 Category: Neurology Source Type: research

Modification of Acute Stroke Pathway in Korea After the Coronavirus Disease 2019 Outbreak
Conclusion: This study demonstrated that the COVID-19 outbreak immediately affected the management process. However, it did not have a significant overall impact on the trends of stroke treatment processes and outcomes. The stroke management process should be modified according to changing situations for optimal acute management.
Source: Frontiers in Neurology - November 19, 2020 Category: Neurology Source Type: research

Stroke Admissions, Stroke Severity, and Treatment Rates in Urban and Rural Areas During the COVID-19 Pandemic
Conclusions: During the early pandemic, deviations of stroke-related admissions from historical averages were observed in both urban and rural regions of Northeastern Germany and appear to have been mainly driven by avoidance of admissions of mildly affected stroke patients.
Source: Frontiers in Neurology - January 6, 2021 Category: Neurology Source Type: research

A case-control analysis of stroke in Covid-19 patients: Results of Unusual Manifestations of Covid-19-Study 11
CONCLUSIONS: The incidence of stroke in COVID-19 patients presenting to EDs was lower than in the non-COVID-19 reference sample. COVID-19 patients with stroke had greater need for hospitalization and ICU admission than those without stroke, and longer hospitalization and greater in-hospital mortality than non-COVID-19 patients with stroke.PMID:34490961 | DOI:10.1111/acem.14389
Source: Accident and Emergency Nursing - September 7, 2021 Category: Emergency Medicine Authors: Eric Jorge Garc ía-Lamberechts Òscar Miró Marcos Fragiel Pere Llorens S ònia Jiménez Pascual Pi ñera Guillermo Burillo Alfonso Mart ín Francisco Javier Mart ín-Sánchez Javier Jacob Aitor Alqu ézar-Arbé Laura Ejarque Mart ínez Bel én Rodrígue Source Type: research

Stroke as an Antecedent Risk Factor for Depression among Post-Menopausal Women
ConclusionsA significant association between previous stroke and current depression was found in this population, independent of vascular disease risk measures among post-menopausal women. These findings highlight the possible importance of screening for and treating depression among stroke survivors. Longitudinal studies need to be conducted assessing the mental health impact of stroke.Key messagesOccurrence of stroke may lead to an increased likelihood of depression, especially among post-menopausal women.Due to the global COVID-19 pandemic, surveillance efforts should include mental health complication including those related to stroke.
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research

E-129 Trends in demographic and geographic disparities of stroke-related mortality in older adults in the United States from 1999 to 2020
Stroke is a leading cause of mortality and morbidity in the United States. Many risk factors are controversial, and their relative importance is not fully understood. Elucidating the association between demographic and geographic disparities and stroke-related mortality in older adults will guide policy to alleviate stroke burden. This retrospective cohort study characterizes stroke-related mortality among individuals aged 55 and older in the United States from January 1999 to December 2020 using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database. Segmented regressio...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: McCandless, M., Powers, A., Baker, K., Strickland, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Implementation of the Stroke Action Plan for Europe 2018--2030 during coronavirus disease-2019
Purpose of review To describe the background, principles and implementation of the Stroke Action Plan for Europe 2018--2030 (SAP-E) in the perspective of the current COVID-19 pandemic. Recent findings SAP-E sets targets for the implementation of evidence-based preventive actions and stroke services to 2030. A recent mapping of stroke care in Europe has documented massive inequalities and even in high-income European countries access to reperfusion therapy and mortality after ischaemic stroke varies significantly. Organized stroke care providing stroke unit care and access to reperfusion therapies reduces mortali...
Source: Current Opinion in Neurology - January 21, 2021 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Valeria Caso Source Type: research

Stroke increases the expression of ACE2, the SARS-CoV-2 binding receptor, in murine lungs
CONCLUSIONS: We demonstrate specific augmented alveolar ACE2 levels and inflammation in murine lungs after experimental stroke. These pre-clinical findings suggest that patients with brain injuries may have increased binding affinity to SARS-CoV-2 in their lungs which might explain why stroke is a risk factor for higher susceptibility to develop COVID-19.PMID:33621620 | DOI:10.1016/j.bbi.2021.01.039
Source: Brain, Behavior, and Immunity - February 23, 2021 Category: Neurology Authors: Vikramjeet Singh Alexander Beer Andreas Kraus Felix Mang Xiaoni Zhang Jinhua Xue Nina Hagemann Dirk M Hermann Matthias Gunzer Source Type: research

Higher Mortality of Ischaemic Stroke Patients Hospitalized with COVID-19 Compared to Historical Controls
Conclusions: Ischaemic stroke patients with COVID-19 had significantly higher 60-day all-cause mortality compared to propensity score-matched historical controls (ischaemic stroke patients without COVID-19).Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 26, 2021 Category: Neurology Source Type: research