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Outcome after acute ischemic stroke treatment during Covid-19 outbreak in South-East Tuscany
CONCLUSION: During the lockdown period due to Covid-19 pandemic, patients with acute ischemic stroke had a worse prognosis. These findings suggest the need to improve the health system organization to guarantee an appropriate treatment during the pandemic, including the patients that are not affected by Covid-19.PMID:34579640 | DOI:10.2174/1871529X21666210927094058
Source: Cardiovascular and Hematological Disorders Drug Targets - September 28, 2021 Category: Drugs & Pharmacology Authors: Maurizio Acampa Valentina Peresso Pietro Enea Lazzerini Carlo Domenichelli Francesca Guideri Rossana Tassi Stefano Dami Roberto Marconi Giovanni Iannelli Giovanni Linoli Giulia Peppoloni Simone Nocentini Simone Gallerini Alessandra Cartocci Sandra Bracco Source Type: research

Patent Foramen Ovale related cryptogenic stroke during COVID-19 disease in three patients: a case series
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), termed COVID-19, first detected in Whuan, was officially declared a pandemic by the World Health Organization on March 11, 2020. The epidemic of COVID-19 has rapidly spread worldwide. Italy was the first European country to be affected and, currently, Italy has reported 4,343,397 COVID-19-positive cases (1).
Source: Journal of Stroke and Cerebrovascular Diseases - September 13, 2021 Category: Neurology Authors: Daniela Palleri, Marta Guidarini, Elisabetta Mariucci, Anna Balducci, Gabriele Egidy Assenza, Susanna Esposito, Andrea Donti Source Type: research

Global research trends in COVID-19 with MRI and PET/CT: a scoping review with bibliometric and network analyses
ConclusionCOVID-19 pandemic is still spreading worldwide, and the knowledge about its different facets continues advancing. MRI and PET/CT are being used in more than 50% of the selected studies; research trends span seven categories, no only the diagnostic but others like socio-economic impact and pathogenesis Developed countries had an advantage by having hospitals with more resources, including MRI and PET/CT facilities in the same institution to supplement basic assessment in patients with COVID-19.
Source: Clinical and Translational Imaging - August 14, 2021 Category: Radiology Source Type: research

Implications of atrial fibrillation on the clinical course and outcomes of hospitalized COVID-19 patients: results of the Cardio-COVID-Italy multicentre study
ConclusionAmong hospitalized patients with COVID-19, a history of AF contributes to worse clinical course with a higher mortality and in-hospital events including new-onset AF, acute HF, and multiorgan failure. The mortality risk remains significant after adjustment for variables associated with COVID-19 severity and comorbidities.
Source: Europace - July 23, 2021 Category: Cardiology Source Type: research

Comorbidity status of deceased COVID-19 in-patients in Italy
CONCLUSION: In those deceased in-hospital due to COVID-19 in Italy, disease combinations defined by multiple cardio-respiratory, metabolic, and neuropsychiatric diseases occur more frequently than expected. This finding indicates a need to investigate the possible role of these clinical profiles in the chain of events that lead to death in individuals who have contracted SARS-CoV-2.PMID:34169447 | DOI:10.1007/s40520-021-01914-y
Source: Aging Clinical and Experimental Research - June 25, 2021 Category: Geriatrics Authors: Davide Liborio Vetrano Clare Tazzeo Luigi Palmieri Alessandra Marengoni Alberto Zucchelli Cinzia Lo Noce Graziano Onder Italian National Institute of Health Covid-Mortality Group Source Type: research

Stroke care in Italy at the time of the COVID-19 pandemic: a lesson to learn
AbstractFrom March to May 2020, the Italian health care system, as many others, was almost entirely devoted to the fight against the COVID-19 pandemic. In this context, a number of questions arose, from the increased stroke risk due to COVID-19 infection to the quality of stroke patient care. The overwhelming need of COVID-19 patient management made mandatory a complete re-organization of the stroke pathways: many health professionals were reallocated and a number of stroke units was turned into COVID-19 wards. As a result, acute stroke care suffered from a shortage of services and delays in time-dependent treatments and d...
Source: Journal of Neurology - June 21, 2021 Category: Neurology Source Type: research

Emergently planned exclusive hub-and-spoke system in the epicenter of the first wave of COVID-19 pandemic in Italy: the experience of the largest COVID-19-free ICU hub for time-dependent diseases
CONCLUSIONS: We described the effects of a regional emergently planned hub-and-spoke system for time-dependent diseases settled in the epicenter of COVID-19 pandemic in Italy.PMID:34102806 | DOI:10.23736/S0375-9393.21.15455-0
Source: Minerva Anestesiologica - June 9, 2021 Category: Anesthesiology Authors: Arturo Chieregato Giacomo Veronese Francesco Curto Matteo Zaniboni Francesca Fossi Fabrizio Zumbo Carla Scattolini Christian Compagnone Beatrice M Alberti Camelia Baciu Lavinia Bergesio Stefano M Carenini Cristiana Cipolla Alessandra C Formentano Alessand Source Type: research

Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature
ConclusionsOur research highlights the large range of neurological manifestations and their presumed pathogenic pathways associated with SARS-CoV-2 infection in children. Nervous system involvement could be isolated, developing during COVID-19 or after its recovery, or arise in the context of a MIS-C. The most reported neurological manifestations are cerebrovascular accidents, reversible splenial lesions, GBS, benign intracranial hypertension, meningoencephalitis; ADEM is also a possible complication, as we observed in our patient. Further studies are required to investigate all the neurological complications of SARS-CoV-2...
Source: Italian Journal of Pediatrics - June 2, 2021 Category: Pediatrics Source Type: research

SARS-CoV-2 infection and acute ischemic stroke in Lombardy, Italy
ConclusionsIschemic strokes in COVID-19 patients have distinctive risk factor profile and etiology, increased clinical severity and higher in-hospital mortality rate compared to non-COVID-19 patients. A simple model based on clinical and routine laboratory parameters may be useful in identifying ischemic stroke patients with SARS-CoV-2 infection who are unlikely to survive the acute phase.
Source: Journal of Neurology - May 24, 2021 Category: Neurology Source Type: research

Effect of anticoagulant therapy in COVID-19 patients
CONCLUSION: Analysis of the literature showed that there was insufficient evidence to answer our objective on the effect of anticoagulation on outcome in COVID-19 patients, especially due to the low scientific quality of the described studies. Randomised controlled studies are needed to answer this question.PMID:33861430 | DOI:10.1007/s12471-021-01574-7
Source: Netherlands Heart Journal - April 16, 2021 Category: Cardiology Authors: R G Tieleman F A Klok E Belfroid J Hoogervorst-Schilp I Schalkers C W Jansen H J Siebelink Source Type: research

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