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Infectious Disease: Lyme Disease
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Total 75 results found since Jan 2013.
Stroke-like Phenomena Revealing Multifocal Cerebral Vasculitis in Pediatric Lyme Neuroborreliosis
We report a previously healthy 12-year-old boy who presented with acute left hemiparesis and meningeal signs. Neuroimaging failed to reveal any cerebral infarction but demonstrated a multifocal cerebral vasculitis involving small, medium and large-sized vessels affecting both the anterior and posterior circulation. Concentric contrast enhancement of the basilar artery was also observed. Further investigations and laboratory findings were consistent with Lyme neuroborreliosis. A rapidly favorable clinical outcome was obtained with appropriate antibiotic treatment along with antiaggregants and steroids. Lyme neuroborreliosis...
Source: Journal of Child Neurology - July 16, 2015 Category: Neurology Authors: Kurian, M., Pereira, V. M., Vargas, M. I., Fluss, J. Tags: Brief Communication Source Type: research
Cerebrovascular Events in Lyme Neuroborreliosis
Cerebrovascular events in neuroborreliosis are a rare condition described only in isolated or small case series. No specific clinical or radiological features have been identified, and diagnosis is based on very different criteria.
Source: Journal of Stroke and Cerebrovascular Diseases - May 19, 2015 Category: Neurology Authors: Basile Wittwer, Sébastien Pelletier, Xavier Ducrocq, Louis Maillard, Gioia Mione, Sébastien Richard Source Type: research
Correspondence Infectious causes of stroke
We read with great interest the excellent Review by Jennifer Fugate and colleagues1 about the infectious causes of stroke. Their Review is useful for daily practice, since physicians often focus excessively on autoimmune causes of central nervous system vasculitis causing stroke, while forgetting about infectious causes. However, we think that apart from neurosyphilis, which is mentioned in great detail, an additional comment on stroke caused by another spirochetal disease, Lyme neuroborreliosis, is needed.
Source: The Lancet Infectious Diseases - May 18, 2015 Category: Infectious Diseases Authors: Adam Garkowski, Joanna Zajkowska, Anna Moniuszko, Piotr Czupryna, Sławomir Pancewicz Tags: Correspondence Source Type: research
Amyotrophic Lateral Sclerosis (ALS) with Laboratory Abnormalities of Unknown Significance (LAUS) --Where Does It Begin and Where Does It End? (P4.144)
CONCLUSIONS: Further detailed analysis of progression rate by site of onset, sex, age, treatment will require assimilation of clinic-based datasets of properly analyzed ALS-LAUS patients from multiple clinic sites. The appropriate role of IVIg in ALS-LAUS patients requires further study following explication of the natural history of these patients compared with non-ALS-LAUS patients. The determination as to whether auto-antibodies to additional antigens may play a role in the progression rate of ALS-LAUS compared with sporadic ALS needs to be systematically studied. Study Supported by: Carolinas ALS Research FundDisclosur...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Brooks, B., Bravver, E., Langford, V., Alwan, M., Smith, N., Lucas, N., Nichols, M., Belcher, S., Lary, C., Nemeth, J., Russo, P., Wright, K., Ward, A., Holsten, S., Fischer, M., Bockenek, W., Desai, U., Lindblom, S. C., Pacicco, T., Sanjak, M. Tags: Neuroepidemiology: ALS Source Type: research
Lyme CNS Infection Mimics Stroke in TeenagerLyme CNS Infection Mimics Stroke in Teenager
Lyme neuroborreliosis can mimic stroke or epilepsy and should be ruled out in some cases of sudden-onset meningoencephalitis with neuropsychiatric symptoms, researchers reported. Medscape Medical News
Source: Medscape Medical News Headlines - March 6, 2015 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news
Teenager with stroke symptoms actually had Lyme disease
(American College of Emergency Physicians) A Swiss teenager, recently returned home from a discotheque, came to the emergency department with classic sudden symptoms of stroke, only to be diagnosed with Lyme disease. The highly unusual case presentation was published online last Thursday in Annals of Emergency Medicine.
Source: EurekAlert! - Infectious and Emerging Diseases - March 2, 2015 Category: Infectious Diseases Source Type: news
Acute Lyme Neuroborreliosis With Transient Hemiparesis and Aphasia
We report a case of a female teenager presenting with sudden-onset aphasia and transient right-sided faciobrachial hemiplegia, along with headache and agitation. Ischemia, vasculitis, or another structural lesion was excluded by brain imaging. Toxicologic evaluation results were negative. Cerebral perfusion computed tomography and electroencephalography showed left parietotemporal brain dysfunction. Lumbar puncture result, although atypical, suggested bacterial infection and intravenous ceftriaxone was initiated. Finally, microbiological cerebrospinal fluid analysis revealed Lyme neuroborreliosis, showing specific intrathe...
Source: Annals of Emergency Medicine - March 2, 2015 Category: Emergency Medicine Source Type: research
Posterior spinal cord infarctions due to neurosyphilis
An 86-year-old patient with multiple vascular risk factors including 3 previous strokes woke up with a sensation of wet lower limbs, with bilateral loss of proprioception in legs on examination. Cervical MRI showed 2 acute medullary ischemic lesions in the posterior columns at level C3 and C4 (figure 1, A–D). Biological screening including HIV serology, Treponema pallidum hemagglutination assay (TPHA), Venereal Disease Research Laboratory test (VDRL), and Lyme disease serology showed an increased TPHA titer of 1:320, with a negative VDRL.
Source: Nature Clinical Practice - December 8, 2014 Category: Neurology Authors: Bill, O., Du Pasquier, R. A., Michel, P. Tags: CT, Parasitic infections, Clinical neurology examination, All Cerebrovascular disease/Stroke, Spinal cord infarction Cases Source Type: research
Clinical Reasoning: A 28-year-old man with progressive gait disturbance and encephalopathy
A 28-year-old man with sickle cell disease presented with 7 months of difficulty walking. Initial examination 3 months prior to admission to our hospital was thought to be consistent with a polyneuropathy. He was areflexic, was unable to stand on toes or heels with decreased sensation on the left foot to light touch and vibration, had difficulty with heel to shin, and was unable to perform tandem gait. Laboratory tests revealed anemia (hemoglobin 7.2 g/dL) and elevated creatinine (1.49 g/dL). HIV, antinuclear antibodies, antineutrophil cytoplasmic antibodies, hepatitis serologies, rapid plasma reagin, thyroid-stimulating h...
Source: Neurology - December 8, 2014 Category: Neurology Authors: Massaro, A. M., Pruitt, A. Tags: Stroke in young adults, MRI, Gait disorders/ataxia, All Oncology RESIDENT AND FELLOW SECTION Source Type: research
Neurological Complications of Lyme Disease
information page compiled by the National Institue of Neurological Disorders and Stroke (NINDS).
Source: NINDS Disorders: National Institute of Neurological Disorders and Stroke - October 26, 2014 Category: Neurology Source Type: research
Vasculitis and stroke due to Lyme neuroborreliosis – a review
Scandinavian Journal of Infectious Diseases, Ahead of Print.
Source: Scandinavian Journal of Infectious Diseases - October 24, 2014 Category: Infectious Diseases Tags: article Source Type: research
A study on the association between infectious burden and Alzheimer's disease
ConclusionsIB consisting of CMV, HSV‐1, B. burgdorferi, C. pneumoniae and H. pylori is associated with AD. This study supports the role of infection/inflammation in the etiopathogenesis of AD.
Source: European Journal of Neurology - June 9, 2014 Category: Neurology Authors: X.‐L. Bu, X.‐Q. Yao, S.‐S. Jiao, F. Zeng, Y.‐H. Liu, Y. Xiang, C.‐R. Liang, Q.‐H. Wang, X. Wang, H.‐Y. Cao, X. Yi, B. Deng, C.‐H. Liu, J. Xu, L.‐L. Zhang, C.‐Y. Gao, Z.‐Q. Xu, M. Zhang, L. Wang, X.‐L. Tan, X. Xu, H.‐D. Zhou, Y. Tags: Original Article Source Type: research
A Better Way To Test Blood Pressure
BOSTON (CBS) – Have you ever had your blood pressure checked in both arms at your doctor’s office? Researchers at Mass General Hospital say you probably should.
A small difference between the two arms is normal. But a larger one could mean you’re at risk for heart disease.
Dr. Ido Weinberg, a vascular medicine specialist, and colleagues at MGH, looked at data on nearly 3,400 local residents over the age of 40 enrolled in the Framingham heart study. “Patients who have that difference between arms could end up developing heart and blood vessel disease,” Dr. Weinberg said.
Researchers found that ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 31, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen blood pressure Dr. Ido Weinberg Dr. Mallika Marshall Mass General Hospital Source Type: news
Potential Misdiagnoses of Bell's Palsy in the Emergency Department
Conclusion: Emergency providers have a very low rate of misdiagnosing Bell's palsy. The association between imaging use and misdiagnosis is likely confounded by patient acuity. Increasing age and diabetes are modest risk factors for misdiagnosis.
Source: Annals of Emergency Medicine - July 29, 2013 Category: Emergency Medicine Authors: Jahan Fahimi, Babak B. Navi, Hooman Kamel Tags: Neurology Source Type: research
Ixodes scapularis Tissue Factor Pathway Inhibitor
Ixodes scapularis is a blood-sucking tick and the principal vector of Lyme disease, a spirochetal illness caused by Borrelia burgdorferi and now the most common vector-borne infection in the United States; more than 50,000 cases have been reported during the last ten years. The salivary gland of I. scapularis has a number of pharmacologically active molecules that help the tick to successfully feed on blood, such as inhibitors of complement system, in addition to coagulation and platelet aggregation inhibitors. This invention describes Ixolaris, a protein that inhibits the initiation of blood coagulation by inhibition of c...
Source: NIH OTT Licensing Opportunities - December 1, 2000 Category: Research Authors: admin Source Type: research
