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Source: Clinical Neurophysiology
Condition: Stroke
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Total 341 results found since Jan 2013.
Flexion Synergy Overshadows Flexor Spasticity During Reaching in Chronic Moderate to Severe Hemiparetic Stroke
Clinicians will be required to quantitatively measure and directly target the contributing underlying motor impairments in individuals with hemiparetic stroke to realize advances beyond conventional care in restoring upper extremity function (Krakauer et al., 2012). In the context of reaching function, impairment in joint individuation is the best predictor of recovery outcome over other common impairments observed in chronic stroke such as weakness and spasticity (Zackowski et al., 2004). The term “spasticity” is defined traditionally as a velocity-dependent hyperactive stretch reflex (Lance, 1980; Thilmann et al., 19...
Source: Clinical Neurophysiology - May 12, 2017 Category: Neuroscience Authors: Michael D. Ellis, Ingrid Schut, Julius P.A. Dewald Source Type: research
Need for updating safety recommendations on repetitive transcranial magnetic stimulation in stroke patients
A paper entitled “Inhibition versus facilitation of contralesional motor cortices in stroke: Deriving a model to tailor brain stimulation” was published by Sankarasubramanian et al. in Clinical Neurophysiology in March 2017 (Sankarasubramanian et al., 2017). That article reported the results of a study that aime d at investigating whether facilitation of contralesional dorsal premotor cortex by repetitive transcranial magnetic stimulation (rTMS) permitted to improve upper-limb function in severely affected post-stroke patients.
Source: Clinical Neurophysiology - June 2, 2017 Category: Neuroscience Authors: Bertrand Glize, Dominique Guehl, M élanie Cogné Tags: Letter to the Editor Source Type: research
O204 Simultaneous bi-hemispheric repetitive transcranial magnetic stimulation for upper limb motor recovery in chronic stroke: A double blind placebo controlled study
repetitive transcranial magnetic stimulation (rTMS) is a promising intervention for the treatment of post-stroke motor deficits. Since the crucial role of non-primary motor cortices and contralesional brain areas is emerging for motor recovery in chronic stroke; we assessed safety and efficacy of bilateral rTMS over the motor areas associated to physical training (PT) on upper extremity (UE) motor function.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Raffaella Chieffo, Giuseppe Scopelliti, Mario Fichera, Giovanni Di Maggio, Roberto Santangelo, Simone Guerrieri, Elise Houdayer, Abraham Zangen, Giancarlo Comi, Letizia Leocani Source Type: research
S186 Effect of reciprocal pedaling exercise on cortical reorganization and gait in stroke patients
Functional impairment of the lower limb is a major complication in stroke patients. The involvement of the cortex in pedaling has critical clinical implications to control of cyclical motor functions in patients with damaged cortical structures or cortical pathways.The study aimed at determining the effect of reciprocal pedaling exercise (RPE) on the gait and cortical reorganization in the stroke patients.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Mahmoud Rezk, Moshera Darweesh, Mohamed ElTamawy, Mye Basheer Source Type: research
S185 The effect of bilateral arm training on motor areas excitability in chronic stroke patients
Physical therapy exercises that do not enhance motor areas neuroplasticity lead to motor impairment especially at the upper extremity (UE) in the chronic stroke patients. The aim of this study was to assess the effect of using bilateral arm training on motor areas excitability (neuroplasticity) in the chronic stroke patients.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Walaa Ragab, Moshera Darwish, Mohamed El Tamawy, Ann Abdel Kader Source Type: research
O174 Preliminary results of testing the recoveriX system on stroke patients
Motor imagery based brain-computer interfaces (BCI) extract the movement intentions of subjects in real-time and can be used to control a cursor or medical devices. In the last years, the control of functional electrical stimulation (FES) devices drew researchers ’ attention for the post-stroke rehabilitation field. In here, a patient can use the movement imagery to artificially induce movements of the paretic arms through FES in real-time.Five patients who had a stroke that affected the motor system participated in the current study, and were trained acro ss 10 to 24 sessions lasting about 40min each with the recoveriX® system.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Danut Irimia, Rupert Ortner, Francisco Fernandes, Christoph Guger, Alexander Heilinger, Martin Walchshofer, Johannes Gruenwald Source Type: research
S31 Structurally informed analyses of functional connectivity in stroke
Stroke is the leading cause of disability in industrialized countries, has a big impact on quality of life, and is of high socioeconomic relevance. Despite great advances of acute therapy – like thrombolysis and mechanical thrombectomy – approximately 50% of stroke survivors suffer from permanent neurological deficits, mostly because of structural and functional neural network failure.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Christian Gerloff Source Type: research
O-2-6-15. Immediate effects of anodal tDCS combined with patterned electrical stimulation on gait performance in patients with stroke
This study aimed to examine the immediate effects of anodal tDCS combined with PES on gait performance in patients with stroke. Twelve patients with subacute stroke participated in this double-masked, sham-controlled cross-over study. They randomly participated in the following sessions on separate days: (1) anodal tDCS+PES; (2) anodal tDCS+sham PES; (3) sham tDCS+PES.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Tomofumi Yamaguchi, Toshiyuki Fujiwara, Kazuhei Maeda, Tsuyoshi Tatemoto, Shigeo Tanabe, Yoko Takahashi, Katsuhiro Mizuno, Yoshihisa Masakado, Meigen Liu Source Type: research
P 167 The functional role of contralesional motor areas in the first days after stroke – an fMRI-guided online TMS-study
Neuroimaging studies in stroke patients with hemiparesis have shown altered brain activation in the contralesional hemisphere including the primary motor cortex (M1), dorsal premotor cortex (dPMC) and anterior intraparietal sulcus (aIPS) already in the first week after stroke (Rehme et al., 2011). The role of these regions for motor recovery is still under debate, with some studies suggesting a supportive influence (Lotze et al., 2006) while other point to a maladaptive role (Nowak et al., 2008).
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: L. Hensel, C. Tscherpel, J. Freytag, S. Ritter, M. Vollmer, L. Volz, G.R. Fink, C. Grefkes Tags: Poster Source Type: research
P 163 Combining TMS and EEG – a new tool to assess motor system integrity after stroke
Despite the wealth of neuroimaging studies regarding stroke pathophysiology and recovery after stroke, there is still a lack of clinically relevant biomarkers that allow to predict the potential of functional recovery and treatment response at individuals ’ level. Anovel approach is to test motor system integrity by means of combining transcranial magnetic stimulation (TMS) and electroencephalography (EEG). By recording TMS-evoked potentials (TEP), the cortical response to TMS, both local and network responses can be recorded and analyzed in indivi dual subjects (Rogasch and Fitzgerald, 2012; Ferreri, 2011).
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: C. Tscherpel, S. Dern, S. Bender, F. M üller-Dahlhaus, U. Ziemann, G.R. Fink, C. Grefkes Tags: Poster Source Type: research
P 67 Electrophysiological correlates of language improvements after intensive language therapy in patients with chronic post-stroke aphasia
Aphasia affects approximately one third of all stroke patients and may lead to chronic disability. Effective neurorehabilitation programs focusing on improving speech and language in patients with post-stroke aphasia are essential. A better understanding of the neurobiological processes accompanying language deficits and rehabilitation may bear fruit in the advancement of neurorehabilitation programs.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: G. Lucchese, F. Pulverm üller, B. Stahl, F. Dreyer, B. Mohr Tags: Poster Source Type: research
P 66 Transcranial DC stimulation enhances recovery of swallowing function after stroke – a randomized clinical and MEG trial
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation tool that has shown some potential to aid motor rehabilitation following stroke. In the present clinical and neuroimaging study we evaluated whether tDCS is able to speed up the recovery of swallowing function in acute dysphagic stroke patients. Besides relating clinical effects with neuroplastic changes in cortical swallowing processing we aimed to identify factors influencing treatment success.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: S. Suntrup-Kr üger, C. Ringmaier, P. Muhle, R. Dziewas Tags: Poster Source Type: research
Revisiting interhemispheric imbalance in chronic stroke: a tDCS study
The immense burden of stroke-related disability has led to the development of noninvasive brain stimulation (NIBS) as a possible approach to augment neurorehabilitation of the paretic upper limb (Ackerley et al., 2010). Transcranial direct current stimulation (tDCS) is a polarity-dependent neuromodulatory technique that has demonstrated some benefit to motor function at the chronic stage (>6 months) post stroke, but effect sizes have varied (Jacobson et al., 2012; Kang et al., 2015).
Source: Clinical Neurophysiology - October 28, 2017 Category: Neuroscience Authors: Alana B McCambridge, James W Stinear, Winston D Byblow Source Type: research
35. Association of robot-assisted rehabilitation and non-invasive brain stimulation to improve upper limb function in chronic stroke patients
Previous studies suggested that both robotic rehabilitation and non-invasive brain stimulation could produce improvement in chronic stroke patients. It is still unknown whether their combination can produce synergistic effects. We designed a proof-of-principle, double-blinded, semi-randomized, sham-controlled trial to assess the safety and efficacy of this combination.Twenty severe upper limb-impaired chronic stroke patients were randomized to robot-assisted therapy associated with real or sham cTBS, delivered for 10 working days.
Source: Clinical Neurophysiology - November 11, 2017 Category: Neuroscience Authors: F. Capone, G. Di Pino, G. Pellegrino, L. Florio, L. Zollo, D. Simonetti, F. Ranieri, N. Brunelli, M. Corbetto, S. Miccinilli, M. Bravi, S. Milighetti, E. Guglielmelli, S. Sterzi, V. Di Lazzaro Source Type: research
26. A randomized controlled cross-over double blind study protocol on THC/CBD oromucosal spray as an add-on therapy for post-stroke spasticity
Understand if cannabinoids (THC:CBD) are useful in reducing post-stroke spasticity using a neurophysiological quantitative measure as primary endpoint.We will recruit 50 patients with spasticity following stroke to take THC:CBD in a double blind placebo-controlled crossover study. Spasticity will be assessed with a numeric rating scale for spasticity, the modified Ashworth scale and with the electromyographic recording of the stretch reflex. The cardiovascular risk will be assessed prior to inclusion.
Source: Clinical Neurophysiology - November 11, 2017 Category: Neuroscience Authors: L. Marinelli, M. Balestrino, L. Mori, L. Puce, G. Rosa, L. Giorello, A. Curr à, F. Fattapposta, C. Serrati, C. Gandolfo, G. Abbruzzese, C. Trompetto Source Type: research
