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Source: Cochrane Database of Systematic Reviews

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Total 466 results found since Jan 2013.

Cognitive rehabilitation for memory deficits after stroke.
CONCLUSIONS: Participants who received cognitive rehabilitation for memory problems following a stroke reported benefits from the intervention on subjective measures of memory in the short term (i.e. the first assessment point after the intervention, which was a minimum of four weeks). This effect was not, however, observed in the longer term (i.e. the second assessment point after the intervention, which was a minimum of three months). There was, therefore, limited evidence to support or refute the effectiveness of memory rehabilitation. The evidence was limited due to the poor quality of reporting in many studies, lack o...
Source: Cochrane Database of Systematic Reviews - August 31, 2016 Category: Journals (General) Authors: das Nair R, Cogger H, Worthington E, Lincoln NB Tags: Cochrane Database Syst Rev Source Type: research

Electromechanical-assisted training for walking after stroke.
CONCLUSIONS: People who receive electromechanical-assisted gait training in combination with physiotherapy after stroke are more likely to achieve independent walking than people who receive gait training without these devices. We concluded that seven patients need to be treated to prevent one dependency in walking. Specifically, people in the first three months after stroke and those who are not able to walk seem to benefit most from this type of intervention. The role of the type of device is still not clear. Further research should consist of large definitive pragmatic phase III trials undertaken to address specific que...
Source: Cochrane Database of Systematic Reviews - May 10, 2017 Category: General Medicine Authors: Mehrholz J, Thomas S, Werner C, Kugler J, Pohl M, Elsner B Tags: Cochrane Database Syst Rev Source Type: research

Repetitive peripheral magnetic stimulation for activities of daily living and functional ability in people after stroke.
CONCLUSIONS: Available trials provided inadequate evidence to permit any conclusions about routine use of rPMS for people after stroke. Additional trials with large sample sizes are needed to determine an appropriate rPMS protocol as well as long-term effects. We identified three ongoing trials and will include these trials in the next review update. PMID: 28644548 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - June 23, 2017 Category: General Medicine Authors: Momosaki R, Yamada N, Ota E, Abo M Tags: Cochrane Database Syst Rev Source Type: research

Interventions for treating urinary incontinence after stroke in adults.
CONCLUSIONS: There is insufficient evidence to guide continence care of adults in the rehabilitative phase after stroke. As few trials tested the same intervention, conclusions are drawn from few, usually small, trials. CIs were wide, making it difficult to ascertain if there were clinically important differences. Only four trials had adequate allocation concealment and many were limited by poor reporting, making it impossible to judge the extent to which they were prone to bias. More appropriately powered, multicentre trials of interventions are required to provide robust evidence for interventions to improve urinary inco...
Source: Cochrane Database of Systematic Reviews - February 1, 2019 Category: General Medicine Authors: Thomas LH, Coupe J, Cross LD, Tan AL, Watkins CL Tags: Cochrane Database Syst Rev Source Type: research

Pharmaceutical interventions for emotionalism after stroke.
CONCLUSIONS: Antidepressants may reduce the frequency and severity of crying or laughing episodes based on very low quality evidence. Our conclusions must be qualified by several methodological deficiencies in the studies and interpreted with caution despite the effect being very large. The effect does not seem specific to one drug or class of drugs. More reliable data are required before appropriate conclusions can be made about the treatment of post-stroke emotionalism. Future trialists investigating the effect of antidepressants in people with emotionalism after stroke should consider developing and using a standardised...
Source: Cochrane Database of Systematic Reviews - March 18, 2019 Category: General Medicine Authors: Allida S, Patel K, House A, Hackett ML Tags: Cochrane Database Syst Rev Source Type: research

Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke.
CONCLUSIONS: Currently there is no evidence of the effectiveness of tDCS (anodal tDCS, cathodal tDCS and Dual-tDCS) versus control (sham tDCS) for improving functional communication in people with aphasia after stroke (low quality of evidence). However, there is limited evidence that tDCS may improve naming performance in naming nouns (moderate quality of evidence), but not verbs (very low quality of evidence) at the end of the intervention period and possibly also at follow-up. Further methodologically rigorous RCTs with adequate sample size calculation are needed in this area to determine the effectiveness of this interv...
Source: Cochrane Database of Systematic Reviews - May 20, 2019 Category: General Medicine Authors: Elsner B, Kugler J, Pohl M, Mehrholz J Tags: Cochrane Database Syst Rev Source Type: research

Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke
CONCLUSIONS: In selected patients with acute ischaemic wake-up stroke, both intravenous thrombolytic treatment and endovascular thrombectomy of large vessel occlusion improved functional outcome without increasing the risk of death. However, a possible increased risk of symptomatic intracranial haemorrhage associated with thrombolytic treatment cannot be ruled out. The criteria used for selecting patients to treatment differed between the trials. All studies were relatively small, and six of the seven studies were terminated early. More studies are warranted in order to determine the optimal criteria for selecting patients...
Source: Cochrane Database of Systematic Reviews - December 1, 2021 Category: General Medicine Authors: Melinda B Roaldsen Haakon Lindekleiv Ellisiv B Mathiesen Source Type: research

Repetitive peripheral magnetic stimulation for impairment and disability in people after stroke
CONCLUSIONS: There is insufficient evidence to permit the drawing of any conclusions about routine use of rPMS for people after stroke. Additional trials with large sample sizes are needed to provide robust evidence for rPMS after stroke.PMID:36169558 | DOI:10.1002/14651858.CD011968.pub4
Source: Cochrane Database of Systematic Reviews - September 28, 2022 Category: General Medicine Authors: Tomohiko Kamo Yoshitaka Wada Masatsugu Okamura Kotomi Sakai Ryo Momosaki Shunsuke Taito Source Type: research

Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke.
CONCLUSIONS: There are significant safety concerns regarding EPO therapy for stroke. It is too early to know whether other CSFs improve functional outcome. PMID: 23797623 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - June 24, 2013 Category: Journals (General) Authors: Bath PM, Sprigg N, England T Tags: Cochrane Database Syst Rev Source Type: research

Transcranial direct current stimulation (tDCS) for improving aphasia in patients after stroke.
CONCLUSIONS: Currently there is no evidence of the effectiveness of tDCS (anodal tDCS, cathodal tDCS) versus control (sham tDCS). However, it appears that cathodal tDCS over the non-lesioned hemisphere might be the most promising approach. PMID: 23799617 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - June 25, 2013 Category: Journals (General) Authors: Elsner B, Kugler J, Pohl M, Mehrholz J Tags: Cochrane Database Syst Rev Source Type: research

Cognitive rehabilitation for spatial neglect following stroke.
CONCLUSIONS: The effectiveness of cognitive rehabilitation interventions for reducing the disabling effects of neglect and increasing independence remains unproven. As a consequence, no rehabilitation approach can be supported or refuted based on current evidence from RCTs. However, there is some very limited evidence that cognitive rehabilitation may have an immediate beneficial effect on tests of neglect. This emerging evidence justifies further clinical trials of cognitive rehabilitation for neglect. However, future studies need to have appropriate high quality methodological design and reporting, to examine persisting ...
Source: Cochrane Database of Systematic Reviews - July 1, 2013 Category: Journals (General) Authors: Bowen A, Hazelton C, Pollock A, Lincoln NB Tags: Cochrane Database Syst Rev Source Type: research