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Source: International Journal of Stroke
Condition: Ischemic Stroke
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Total 291 results found since Jan 2013.
A simple 8‐point score strongly predicts early outcomes in acute stroke
ConclusionsA simple 8‐point clinical score is highly predictive of acute stroke mortality and length of hospital stay. It could be used as prognostic tool in service planning and also to risk‐stratify patients to use these outcomes as markers of stroke care quality across institutions.
Source: International Journal of Stroke - July 9, 2013 Category: Neurology Authors: Phyo Kyaw Myint, Allan B. Clark, Chun Shing Kwok, John Davis, Ramesh Durairaj, Anand K. Dixit, Anil K. Sharma, Gary A. Ford, John F. Potter Tags: Research Source Type: research
Outcomes for people with atrial fibrillation in an Australian national audit of stroke care
ConclusionsHospital processes of care can influence outcomes in stroke patients with atrial fibrillation. The greater in‐hospital mortality experienced by stroke patients with atrial fibrillation may be attenuated by admission to a stroke unit, and for ischemic stroke, early administration of aspirin.
Source: International Journal of Stroke - July 9, 2013 Category: Neurology Authors: Nadine Andrew, Monique Kilkenny, Dawn Harris, Chris Price, Dominique A. Cadilhac Tags: Research Source Type: research
Comparison between angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers on the risk of stroke recurrence and longitudinal progression of white matter lesions and silent brain infarcts on MRI (CEREBRAL study): rationale, design, and methodology
ConclusionsOur study will clarify whether angiotensin‐converting enzyme inhibitors or angiotensin II receptor blockers are more effective for preventing primary and recurrence of ischemic stroke, including the progression of asymptomatic cerebral lesions on magnetic resonance imaging, in elderly hypertensive patients.
Source: International Journal of Stroke - July 9, 2013 Category: Neurology Authors: Shigeru Yamano, Manabu Horii, Takeshi Takami, Mio Sakuma, Takeshi Morimoto, Sadanori Okada, Toshiaki Taoka, Kimihiko Kichikawa, Hiroyuki Sasamura, Hiroshi Itoh, Yoshiko Furuya, Satoshi Ueno, Tomoaki Imamura, Seigo Sugiyama, Hisao Ogawa, Yoshihiko Saito Tags: Protocols Source Type: research
Combining magnetic resonance imaging within six‐hours of symptom onset with clinical follow‐up at 24 h improves prediction of ‘malignant’ middle cerebral artery infarction
ConclusionClinical follow‐up examination after 24 h helps identify patients at risk of ‘malignant’ middle cerebral artery infarction that are missed by predictive algorithms based on early diffusion‐weighted imaging lesion volume alone.
Source: International Journal of Stroke - July 9, 2013 Category: Neurology Authors: Anna Kruetzelmann, Frank Hartmann, Christoph Beck, Eric Juettler, Oliver C. Singer, Martin Köhrmann, Jan F. Kersten, Jan Sobesky, Christian Gerloff, Arno Villringer, Jens Fiehler, Tobias Neumann‐Haefelin, Peter D. Schellinger, Joachim Röther, Götz Th Tags: Research Source Type: research
The SOAR (Stroke subtype, Oxford Community Stroke Project classification, Age, prestroke modified Rankin) score strongly predicts early outcomes in acute stroke
ConclusionsA simple 8‐point clinical score is highly predictive of acute stroke mortality and length of hospital stay. It could be used as prognostic tool in service planning and also to risk‐stratify patients to use these outcomes as markers of stroke care quality across institutions.
Source: International Journal of Stroke - July 9, 2013 Category: Neurology Authors: Phyo Kyaw Myint, Allan B. Clark, Chun Shing Kwok, John Davis, Ramesh Durairaj, Anand K. Dixit, Anil K. Sharma, Gary A. Ford, John F. Potter Tags: Research Source Type: research
Aortic stiffness measurement improves the prediction of asymptomatic coronary artery disease in stroke/transient ischemic attack patients
ConclusionsIn stroke/transient ischemic attack patients, aortic pulse wave velocity improves the prediction of ≥50% asymptomatic coronary artery disease beyond classical risk factors.
Source: International Journal of Stroke - July 1, 2013 Category: Neurology Authors: David Calvet, Emmanuel Touzé, Stéphane Laurent, Olivier Varenne, Jean‐Louis Sablayrolles, Pierre Boutouyrie, Jean‐Louis Mas Tags: Research Source Type: research
Strategies to improve recovery in acute ischemic stroke patients: Iberoamerican Stroke Group Consensus
Stroke is not only a leading cause of death worldwide but also a main cause of disability. In developing countries, its burden is increasing as a consequence of a higher life expectancy. Whereas stroke mortality has decreased in developed countries, in Latin America, stroke mortality rates continue to rise as well as its socioeconomic dramatic consequences. Therefore, it is necessary to implement stroke care and surveillance programs to better describe the epidemiology of stroke in these countries in order to improve therapeutic strategies. Advances in the understanding of the pathogenic processes of brain ischemia have re...
Source: International Journal of Stroke - June 29, 2013 Category: Neurology Authors: M Alonso de Leciñana, M Gutiérrez‐Fernández, M Romano, C Cantú‐Brito, A Arauz, LE Olmos, SF Ameriso, E Díez‐Tejedor, Tags: Review Source Type: research
Apparent diffusion coefficient threshold for delineation of ischemic core
ConclusionsOur data suggest that the ischemic core can be identified with an absolute apparent diffusion coefficient threshold. This threshold can be implemented in image analysis software for fully automated segmentation of the ischemic core.
Source: International Journal of Stroke - June 27, 2013 Category: Neurology Authors: Archana Purushotham, Bruce C. V. Campbell, Matus Straka, Michael Mlynash, Jean‐Marc Olivot, Roland Bammer, Stephanie M. Kemp, Gregory W. Albers, Maarten G. Lansberg Tags: Research Source Type: research
How much diffusion lesion reversal occurs after treatment within three‐hours of stroke onset?
In this issue of the journal, Sakamoto et al. present an analysis of diffusion lesion evolution in acute ischemic stroke patients first imaged less than three‐hours from stroke onset. Although temporary lesion volume reduction was observed following reperfusion, the affected regions were generally abnormal on follow‐up fluid attenuated inversion recovery imaging, indicating lack of tissue salvage. Taken in conjunction with other recent articles, it seems that temporary postreperfusion ‘reversal’ of diffusion lesions is quite common but usually does not translate to permanent tissue salvage. A minority of patients...
Source: International Journal of Stroke - June 20, 2013 Category: Neurology Authors: Bruce C. V. Campbell, Stephen M. Davis, Geoffrey A. Donnan Tags: Leading opinion Source Type: research
Vitamin D deficiency and its relation to underlying stroke etiology in ethnic Asian ischemic stroke patients
Source: International Journal of Stroke - June 20, 2013 Category: Neurology Authors: Deidre Anne De Silva, Loreto P. Talabucon, Ebonne Yulin Ng, Elaine Shu Ling Ang, Eng King Tan, Wei Ling Lee Tags: Letter to the editor Source Type: research
A double‐blind placebo‐controlled clinical evaluation of MultiStem for the treatment of ischemic stroke
Conclusions and future directionIf MultiStem is safe and there is a signal of efficacy, a late stage phase IIb‐III trial is planned.
Source: International Journal of Stroke - May 24, 2013 Category: Neurology Authors: David C. Hess, Cathy A. Sila, Anthony J. Furlan, Larry R. Wechsler, Jeffrey A. Switzer, Robert W. Mays Tags: Protocols Source Type: research
Thrombolysis for acute ischemic stroke in South Africa
ConclusionsOur findings indicate that the use of thrombolysis in routine clinical practice in a South African setting has similar safety and early efficacy outcomes to developed and other developing countries.
Source: International Journal of Stroke - May 22, 2013 Category: Neurology Authors: Alan Bryer, Sean Wasserman Tags: Short Report Source Type: research
Enlarged perivascular spaces and cerebral small vessel disease
ConclusionsEnlarged perivascular spaces are associated with age, lacunar stroke subtype and white matter lesions and should be considered as another magnetic resonance imaging marker of cerebral small vessel disease. Further evaluation of enlarged perivascular spaces in studies of ageing, stroke, and dementia is needed to determine their pathophysiological importance.
Source: International Journal of Stroke - May 22, 2013 Category: Neurology Authors: Gillian M. Potter, Fergus N. Doubal, Caroline A. Jackson, Francesca M. Chappell, Cathie L. Sudlow, Martin S. Dennis, Joanna M. Wardlaw Tags: Research Source Type: research
Paracetamol (Acetaminophen) in stroke 2 (PAIS 2): Protocol for a randomized, placebo‐controlled, double‐blind clinical trial to assess the effect of high‐dose paracetamol on functional outcome in patients with acute stroke and a body temperature of 36·5°C or above
DiscussionIf high‐dose paracetamol will be proven effective, a simple, safe, and extremely cheap therapy will be available for many patients with acute stroke worldwide.
Source: International Journal of Stroke - May 22, 2013 Category: Neurology Authors: Inger R. Ridder, Frank Jan Jong, Heleen M. Hertog, Hester F. Lingsma, H. Maarten A. Gemert, A. H. C. M. L. (Tobien) Schreuder, Annemieke Ruitenberg, E. (Lisette) Maasland, Ritu Saxena, Peter Oomes, Jordie Tuijl, Peter J. Koudstaal, L. Jaap Kappelle, Ale A Tags: Protocols Source Type: research
Effect of addition of clopidogrel to aspirin on stroke incidence: Meta‐analysis of randomized trials
ConclusionsThis meta‐analysis demonstrates a substantial relative risk reduction in stroke by clopidogrel plus aspirin vs. aspirin alone that is consistent across different trial cohorts. Major haemorrhage is increased by dual antiplatelet therapy.
Source: International Journal of Stroke - May 22, 2013 Category: Neurology Authors: Santiago Palacio, Robert G. Hart, Lesly A. Pearce, David C. Anderson, Mukul Sharma, Lee A. Birnbaum, Oscar R. Benavente Tags: Research Source Type: research
