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Source: International Journal of Stroke
Condition: Ischemic Stroke
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Total 291 results found since Jan 2013.
Validation of a TIA recognition tool in primary and secondary care: implications for generalizability
ConclusionThe Dawson transient ischemic attack recognition score is less accurate in primary care than in its derivation setting of specialist care. Improving the recognition of transient ischemic attack by providers of first contact health care requires derivation of rules in the clinical setting in which they are to be used.
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Daniel S. Lasserson, David Mant, F. D. Richard Hobbs, Peter M. Rothwell Tags: Research Source Type: research
Differential effects of paracrine factors on the survival of cells of the neurovascular unit during oxygen glucose deprivation
ConclusionMicroglia‐derived signaling molecules, but not angiogenic factors, were protective for neurovascular unit cells during oxygen glucose deprivation. This finding could identify a potential therapeutic target for ischemic stroke.
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Zoran B. Redzic, Tamer Rabie, Brad A. Sutherland, Alastair M. Buchan Tags: Research Source Type: research
The burden of stroke in México
Regrettably, stroke has been scarcely studied in México, and the available data suffer from great variability in diagnostic testing, risk factor definitions, and poor generalizability. The current cumulative incidence of stroke in Mexico is 232·2 per 100 000, whereas prevalence among people aged 60 years or older is 18·2 per 1000.
Hypertension and diabetes are the main risk factors. Ischemic stroke is the most frequent sub‐type. Stroke mortality has been increasing during last years, and 30‐day case fatality rate doubles at one‐year follow‐up. A remarkable finding of a hospital‐based registry was that most o...
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Juan M Marquez‐Romero, Antonio Arauz, Fernando Góngora‐Rivera, Fernando Barinagarrementeria, Carlos Cantú Tags: Panorama Source Type: research
Prevention of poststroke cognitive decline: ASPIS – a multicenter, randomized, observer‐blind, parallel group clinical trial to evaluate multiple lifestyle interventions – study design and baseline characteristics
ConclusionThe recruitment was successful and the groups are balanced regarding potential confounding variables. The study will provide essential data about the feasibility and efficacy of lifestyle intervention after stroke in order to develop a new approach to prevent cognitive decline in patients with mild ischemic stroke.
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Michael Brainin, Karl Matz, Matthias Nemec, Yvonne Teuschl, Alexandra Dachenhausen, Susanne Asenbaum‐Nan, Christian Bancher, Berthold Kepplinger, Stefan Oberndorfer, Michaela Pinter, Peter Schnider, Jaakko Tuomilehto, Tags: Protocols Source Type: research
Potential gains and costs from increasing access to thrombolysis for acute ischemic stroke patients in New Zealand hospitals
ConclusionWhile thrombolysis is a cost‐effective treatment in New Zealand, resources should be devoted to campaigns, both within hospitals and in the community, to increase coverage.
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Braden Te Ao, Paul Brown, John Fink, Mark Vivian, Valery Feigin Tags: Research Source Type: research
Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol
Therapeutic hypothermia improves neurological outcome after out‐of‐hospital cardiac arrest or neonatal hypoxic–ischemic injury. Although supported by preclinical evidence, therapeutic hypothermia for acute stroke remains under study. In the Intravascular Cooling in the Treatment of Stroke (ICTuS) trial, awake stroke patients were successfully cooled using an endovascular cooling catheter and a novel antishivering regimen. In the ICTuS‐L study, the combination of endovascular hypothermia and thrombolysis proved feasible; while hypothermia was associated with no increased risk of bleeding complications, there was an ...
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Patrick D. Lyden, Thomas M. Hemmen, James Grotta, Karen Rapp, Rema Raman Tags: Protocols Source Type: research
Methodology of a population‐based stroke and TIA incidence and outcomes study: The Auckland Regional Community Stroke Study (ARCOS IV) 2011–2012
ConclusionsThe methodology described may be used as a guide in order to design similar population‐based stroke incidence and outcome studies in other countries and populations, thus facilitating the collection of most consistent and accurate stroke epidemiological data.
Source: International Journal of Stroke - October 27, 2013 Category: Neurology Authors: Rita Krishnamurthi, Amy Jones, P Alan Barber, Suzanne Barker‐Collo, Kathryn McPherson, Derrick Bennett, Elaine Rush, Flora Suh, Nicola Starkey, Alice Theadom, Varsha Parag, Yogini Rathnasabapathy, Valery L. Feigin, Tags: Protocol (Invited) Source Type: research
Body mass index and acute ischemic stroke outcomes
ConclusionsBeing overweight or obese is associated with a better functional outcome and reduced mortality in patients of acute ischemic stroke. However, the definition of an ‘optimal’ body mass index, in relation to stroke outcomes, may be affected by age, gender, and use of thrombolytic therapy.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: M. Saini, M. Saqqur, A. Shuaib, Tags: Research Source Type: research
A comparative analysis of risk factors and stroke risk for Asian and non‐Asian men: The Asia Pacific Cohort Studies Collaboration
ConclusionsMen from the Asia‐Pacific region share common risk factors for stroke. Strategies aimed at lowering population levels of systolic blood pressure, total cholesterol, body mass index, smoking, and diabetes are likely to be beneficial in reducing stroke risk, particularly for ischemic stroke, across the region.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Karice K. Hyun, Rachel R. Huxley, Hisatomi Arima, Jean Woo, Tai Hing Lam, Hirotsugu Ueshima, Xianghua Fang, Sanne A. E. Peters, Sun Ha Jee, Graham G. Giles, Federica Barzi, Mark Woodward Tags: Research Source Type: research
Edaravone improves functional and structural outcomes in animal models of focal cerebral ischemia: A systematic review
Edaravone has been used in patients with acute ischemic stroke in Japan for over 10 years but does not have marketing authorization in Europe or America. Either patients in Europe and America are not receiving an effective treatment, or those in Asia are being given a treatment which is not effective. Finding out which of these is true will require further clinical trials, and a better understanding of its efficacy in animal models may help inform the design of those trials so that it might be tested under conditions where there is the greatest prospect of success. We systematically reviewed the efficacy of edaravone in an...
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Simiao Wu, Emily Sena, Kieren Egan, Malcolm Macleod, Gillian Mead Tags: Systematic Review Source Type: research
Influence of racial differences on outcomes after thrombolytic therapy in acute ischemic stroke
ConclusionsThese results do not suggest a differential response to tissue plasminogen activator based on race ethnicity. Among Asians, data were particularly sparse, and results should be interpreted with caution.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Nishant K. Mishra, Pitchaiah Mandava, Christopher Chen, James Grotta, Kennedy R. Lees, Thomas A. Kent, Tags: Research Source Type: research
Carotid intima‐media thickness – a potential predictor for rupture risk of intracranial aneurysms
ConclusionThere is an association between IMT and intracranial aneurysm rupture status at the time of aneurysm treatment. Carotid IMT can be a potential predictor of aneurysm rupture. IMT may thus be a possible adjunct in the risk assessment of aneurysm rupture, and a helpful tool in patient risk stratification and counseling.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Marianne Lundervik, Annette Fromm, Øystein Ariansen Haaland, Ulrike Waje‐Andreassen, Frode Svendsen, Lars Thomassen, Christian A. Helland Tags: Research Source Type: research
Novel oral anticoagulants: A focused review for stroke physicians
Novel oral anticoagulants provide an effective and convenient alternative to warfarin for stroke prevention in patients with atrial fibrillation. However, novel anticoagulants also present new challenges for stroke physicians, such as measurement of anticoagulant effect in emergency situations, use of thrombolysis in acute ischemic stroke, optimal timing of introduction of novel anticoagulants following acute ischemic stroke, and management of intracerebral hemorrhage. In this review, we propose pragmatic approaches to dealing with challenging management issues that will face stroke physicians who care for patients with ac...
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Emer R. McGrath, John W. Eikelboom, Moira K. Kapral, Martin J. O'Donnell Tags: Review Source Type: research
Incidence and outcome of cerebrovascular events related to cervical artery dissection: the Dijon Stroke Registry
ConclusionThe incidence of cerebrovascular events related to vertebral artery dissection is greater than previously reported, which may indicate a better identification of patients due to improvements in diagnostic procedures.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Yannick Béjot, Benoit Daubail, Stéphanie Debette, Jérôme Durier, Maurice Giroud Tags: Research Source Type: research
Types of stroke recurrence in patients with ischemic stroke: A substudy from the PRoFESS trial
ConclusionsRisk predictors for stroke recurrence and for brain hemorrhage differ by index ischemic stroke subtype, information that is important when initiating secondary prevention therapy.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Danilo Toni, Emanuele Di Angelantonio, Maria Teresa Di Mascio, Richard Vinisko, Philip MW Bath, Tags: Research Source Type: research
