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Source: International Journal of Stroke
Condition: Ischemic Stroke
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Total 291 results found since Jan 2013.
iPad Technology for Home Rehabilitation after Stroke (iHOME): A proof‐of‐concept randomized trial
ConclusionsiHOME is a randomized controlled trial assessing the feasibility, safety, and efficacy of tablet technology for home use in stroke rehabilitation. The results of this study will serve as the basis for a larger multicenter trial.
Source: International Journal of Stroke - July 7, 2014 Category: Neurology Authors: Gustavo Saposnik, Chi‐Ming Chow, David Gladstone, Donna Cheung, Edward Brawer, Kevin E. Thorpe, Avon Saldanha, Alice Dang, Mark Bayley, Tom A. Schweizer, Tags: Protocols Source Type: research
Baseline characteristics and treatment response of patients from the Philippines in the CHIMES study
ConclusionsThe treatment effects in the Philippine cohort were in favor of MLC601. This may be due to inclusion of more patients with predictors of poorer outcome.
Source: International Journal of Stroke - July 7, 2014 Category: Neurology Authors: Jose C. Navarro, Herminigildo H. Gan, Annabelle Y. Lao, Alejandro C. Baroque, John H. B. Hiyadan, Carlos L. Chua, Ma. Cristina San Jose, Joel M. Advincula, Chun Fan Lee, Marie‐Germaine Bousser, Christopher L. H. Chen, Tags: Short Report Source Type: research
Burden of stroke in Egypt: current status and opportunities
Middle East and North Africa (MENA) countries have a diversity of populations with similar life style, dietary habits, and vascular risk factors that may influence stroke risk, prevalence, types, and disease burden. Egypt is the most populated nation in the Middle East with an estimated 85.5 million people. In Egypt, according to recent estimates, the overall prevalence rate of stroke is high with a crude prevalence rate of 963/100 000 inhabitants. In spite of disease burden, yet there is a huge evidence practice gap. The recommended treatments for ischemic stroke that are guideline include systematic supportive care in ...
Source: International Journal of Stroke - July 7, 2014 Category: Neurology Authors: Foad Abd‐Allah, Ramez Reda Moustafa Tags: Panorama Source Type: research
Baseline characteristics of the 4011 patients recruited into the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial
ConclusionENOS is a large completed international trial of blood pressure management in acute stroke and includes patients representative of many stroke services worldwide.
Source: International Journal of Stroke - July 1, 2014 Category: Neurology Tags: Research Source Type: research
Prediction of recanalization in acute stroke patients receiving intravenous and endovascular revascularization therapy
ConclusionThe overall likelihood of recanalization was the highest in the endovascular group, and higher for intravenous thrombolysis compared with no revascularization therapy. However, our statistical models of recanalization for each individual patient indicate significant variability between treatment options, suggesting the need to include this prediction in the personalized treatment selection.
Source: International Journal of Stroke - June 30, 2014 Category: Neurology Authors: Guangming Zhu, Patrik Michel, Tudor Jovin, James T. Patrie, Wenjun Xin, Ashraf Eskandari, Weiwei Zhang, Max Wintermark Tags: Research Source Type: research
Impact of living and socioeconomic characteristics on cardiovascular risk in ischemic stroke patients
ConclusionVascular risk in stroke patients in low‐ and middle‐income countries varies not only with the number of arterial beds involved but also with socioeconomic variables.
Source: International Journal of Stroke - June 13, 2014 Category: Neurology Authors: Pierre Amarenco, Halim Abboud, Julien Labreuche, Antonio Arauz, Alan Bryer, Pablo M. Lavados, Ayrton Massaro, Mario Munoz Collazos, Philippe Gabriel Steg, Bassem I. Yamout, Eric Vicaut, Tags: Research Source Type: research
Trimming the fat in acute ischemic stroke: an assessment of 24‐h CT scans in tPA patients
ConclusionsOur results demonstrate that routine 24‐h computed tomography scan in patients without 24‐h National Institute of Health Stroke Scale worsening (especially those with baseline National Institute of Health Stroke Scale ≤10) is less likely to yield information that results in a deviation from standard acute stroke care. No patient without worsening and baseline National Institute of Health Stroke Scale ≤10 had parenchymal hematoma on 24‐h computed tomography. Application of the National Institute of Health Stroke Scale to distinguish patients who should have 24‐h follow‐up imaging from those who will...
Source: International Journal of Stroke - June 3, 2014 Category: Neurology Authors: Alexander J. George, Amelia K. Boehme, Casey R. Dunn, T. Beasley, James E. Siegler, Karen C. Albright, Ramy El Khoury, Sheryl Martin‐Schild Tags: Research Source Type: research
Management of acute stroke in patients taking novel oral anticoagulants
Each year, 1·0–2·0% of individuals with atrial fibrillation and 0·1–0·2% of those with venous thromboembolism who are receiving one of the novel oral anticoagulants (dabigatran, rivaroxaban, or apixaban) can be expected to experience an acute ischemic stroke. Additionally, 0·2–0·5% of individuals with atrial fibrillation who are receiving one of the novel oral anticoagulants can be expected to experience an intracranial hemorrhage. This opinion piece addresses the current literature and offers practical approaches to the management of patients receiving novel oral anticoagulants who present with an ischemic or ...
Source: International Journal of Stroke - June 1, 2014 Category: Neurology Authors: Graeme J. Hankey, Bo Norrving, Werner Hacke, Thorsten Steiner Tags: Review Source Type: research
Acute imaging does not improve ASTRAL score's accuracy despite having a prognostic value
ConclusionsThe addition of information derived from multimodal imaging does not increase ASTRAL score's accuracy to predict functional outcome despite having an independent prognostic value. More selected radiological parameters applied in specific subgroups of stroke patients may add prognostic value of multimodal imaging.
Source: International Journal of Stroke - June 1, 2014 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Mohamed Faouzi, Peter Vanacker, Max Wintermark, Patrik Michel Tags: Research Source Type: research
The THRIVE score strongly predicts outcomes in patients treated with the Solitaire device in the SWIFT and STAR trials
ConclusionsThe THRIVE score strongly predicts clinical outcome and mortality in patients treated with the Solitaire device in the SWIFT and STAR trials. The lack of interaction between THRIVE and procedure‐specific elements such as vessel recanalization or device choice makes the THRIVE score a reasonable candidate for use as a patient selection criterion in stroke clinical trials.
Source: International Journal of Stroke - May 22, 2014 Category: Neurology Authors: Alexander C. Flint, Sean P. Cullen, Vivek A. Rao, Bonnie S. Faigeles, Vitor M. Pereira, Elad I. Levy, Tudor G. Jovin, David S. Liebeskind, Raul G. Nogueira, Reza Jahan, Jeffrey L. Saver, Tags: Research Source Type: research
The real stroke burden in the Philippines
Stroke is the Philippines' second leading cause of death. It has a prevalence of 0·9%; ischemic stroke comprises 70% while hemorrhagic stroke comprises 30%. Age‐adjusted hypertension prevalence is 20·6%, diabetes 6·0%, dyslipidemia 72·0%, smoking 31%, and obesity 4·9%. The neurologist‐to‐patient ratio is 1:330·000, with 67% of neurologists practicing in urban centers. Health care is largely private and the cost is borne out‐of‐pocket by patients and their families. Challenges include delivering adequate support to the rural communities and to the underprivileged sectors.
Source: International Journal of Stroke - May 20, 2014 Category: Neurology Authors: Jose C. Navarro, Alejandro C. Baroque, Johnny K. Lokin, Narayanaswamy Venketasubramanian Tags: Panorama Source Type: research
Prescription frequency and predictors for the use of novel direct oral anticoagulants for secondary stroke prevention in the first year after their marketing in Europe – a multicentric evaluation
ConclusionsShortly after their marketing, DOAC are used as frequently as VKA for secondary stroke prevention in patients with atrial fibrillation. The decision between VKA and DOAC is mainly determined by the patient's renal function and the absence or presence of prior oral anticoagulant therapy.
Source: International Journal of Stroke - May 15, 2014 Category: Neurology Authors: Sebastian Luger, Carina Hohmann, Peter Kraft, Ramona Halmer, Ignaz Gunreben, Tobias Neumann‐Haefelin, Christoph Kleinschnitz, Silke Walter, Veronika Haripyan, Helmuth Steinmetz, Christian Foerch, Waltraud Pfeilschifter Tags: Research Source Type: research
EuroHYP‐1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke
DiscussionWith 750 patients per intervention group, this trial has 90% power to detect 7% absolute improvement at the 5% significance level. The full trial protocol is available at http://www.eurohyp1.eu. ClinicalTrials.gov Identifier: NCT01833312.
Source: International Journal of Stroke - May 15, 2014 Category: Neurology Authors: H. Bart Worp, Malcolm R. Macleod, Philip M. W. Bath, Jacques Demotes, Isabelle Durand‐Zaleski, Bernd Gebhardt, Christian Gluud, Rainer Kollmar, Derk W. Krieger, Kennedy R. Lees, Carlos Molina, Joan Montaner, Risto O. Roine, Jesper Petersson, Dimitre Sta Tags: Protocols Source Type: research
A questionnaire survey of general practitioners in Japan in relation to management of transient ischemic attack
Source: International Journal of Stroke - May 5, 2014 Category: Neurology Authors: Rieko Suzuki, Toshiyuki Uehara, Tomoyuki Ohara, Kazuya Kawabata, Keizo Yasui, Yasuhiro Hasegawa, Kazuo Minematsu Tags: Letter to the editor Source Type: research
Hemicraniectomy for malignant middle cerebral artery infarction: Current status and future directions
Malignant middle cerebral artery infarction is a life‐threatening sub‐type of ischemic stroke that may only be survived at the expense of permanent disability. Decompressive hemicraniectomy is an effective surgical therapy to reduce mortality and improve functional outcome without promoting most severe disability. Evidence derives from three European randomized controlled trials in patients up to 60 years. The recently finished DEcompressive Surgery for the Treatment of malignant INfarction of the middle cerebral arterY – II trial gives now high‐level evidence for the effectiveness of decompressive hemicraniectomy ...
Source: International Journal of Stroke - April 11, 2014 Category: Neurology Authors: Hermann Neugebauer, Eric Jüttler Tags: Review Source Type: research
