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Source: Acta Neurologica Scandinavica

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Total 185 results found since Jan 2013.

Risk factor burden predicts long‐term mortality after cerebral infarction
ConclusionIncreasing number of traditional risk factors is associated with long‐term mortality in patients with cerebral infarction, irrespective of age. Careful long‐term follow‐up is important, especially among patients with several risk factors.
Source: Acta Neurologica Scandinavica - June 27, 2013 Category: Neurology Authors: G. Gjerde, H. Naess Tags: Original Article Source Type: research

Ultraearly assessed reperfusion status after middle cerebral artery recanalization predicting clinical outcome
ConclusionsUltraearly quantitative assessment of reperfusion status after successful MCA recanalization reveals post‐procedural cortical rTTP as possible independent prognostic value in predicting favorable clinical outcome, even determining a threshold value might be possible. In consequence, focusing stroke therapy on microcirculatory patency could be valuable to improve outcome.
Source: Acta Neurologica Scandinavica - February 9, 2018 Category: Neurology Authors: P. G ölitz, I. Muehlen, S. T. Gerner, F. Knossalla, A. Doerfler Tags: ORIGINAL ARTICLE Source Type: research

High‐frequency rTMS using a double cone coil for gait disturbance
ConclusionsHigh‐frequency rTMS of bilateral leg motor areas using a double cone coil can potentially improve walking function in post‐stroke hemiparetic patients.
Source: Acta Neurologica Scandinavica - February 7, 2013 Category: Neurology Authors: W. Kakuda, M. Abo, Y. Nakayama, A. Kiyama, H. Yoshida Tags: Original Article Source Type: research

Organizational changes aiming to reduce iv tPA door‐to‐needle time
ConclusionsStreamlining of iv tPA logistics can reduce median DNT to <30 min in a general local hospital. Moving treatment start from the ER to the CT laboratory contributed to reduce DNT. Our organizational model was resistant to influence on DNT by patient age, gender, stroke severity, and time to hospital arrival. The incidence of SICH remained low.
Source: Acta Neurologica Scandinavica - November 23, 2013 Category: Neurology Authors: E. T. Thortveit, M. G. Bøe, U. Ljøstad, Å. Mygland, A. Tveiten Tags: Original Article Source Type: research

Prediction of myocardial infarction in patients with transient ischaemic attack
ConclusionAccording to our results, discrimination was poor for all previous risk prediction models evaluated. Variables such as previous CHD, male sex, DWI and ECG abnormalities should be considered in new prediction models.
Source: Acta Neurologica Scandinavica - October 10, 2014 Category: Neurology Authors: M. B. Vilanova, G. Mauri‐Capdevila, J. Sanahuja, A. Quilez, G. Piñol‐Ripoll, R. Begué, M. I. Gil, M. C. Codina‐Barios, I. Benabdelhak, F. Purroy Tags: Original Article Source Type: research

Resveratrol improves delayed r‐tPA treatment outcome by reducing MMPs
ConclusionsResveratrol could be potentially administered as an adjuvant with r‐tPA treatment, which extends the clinical therapeutic window of r‐tPA, therefore improving the outcome of patients receiving late stroke treatment.
Source: Acta Neurologica Scandinavica - October 13, 2015 Category: Neurology Authors: J. Chen, Q. Bai, Z. Zhao, H. Sui, X. Xie Tags: Original Article Source Type: research

Leptomeningeal collateral status predicts outcome after middle cerebral artery occlusion
ConclusionsLeptomeningeal collateral status predicts functional outcome, mortality, and hemorrhagic transformation following middle cerebral artery occlusion.
Source: Acta Neurologica Scandinavica - September 14, 2017 Category: Neurology Authors: C. F. Madelung, C. Ovesen, C. Trampedach, A. Christensen, I. Havsteen, C. K. Hansen, H. Christensen Tags: ORIGINAL ARTICLE Source Type: research

High risk of early neurological worsening of lacunar infarction
ConclusionsLacunar infarctions with minor neurological deficits within 3  hours of stroke onset are at high risk of neurological worsening especially if concomitant low body temperature and leukoaraiosis.
Source: Acta Neurologica Scandinavica - October 5, 2018 Category: Neurology Authors: Halvor Naess, Lars Thomassen, Ulrike Waje ‐Andreassen, Solveig Glad, Christopher E. Kvistad Tags: ORIGINAL ARTICLE Source Type: research

Association between neurological disorders, functioning, and mortality in the elderly
ConclusionsWe found that not only specific neurological disorders, but also earlier symptoms are related to impaired functioning and predict mortality in the elderly. These findings have potential clinical relevance for screening and early detection of individuals at risk.
Source: Acta Neurologica Scandinavica - February 3, 2014 Category: Neurology Authors: M. E. Czira, B. T. Baune, A. Roesler, K. Pfadenhauer, C. Trenkwalder, K. Berger Tags: Original Article Source Type: research

Burden and cost of neurological diseases: a European North–South comparison
ConclusionsHealth expenditure, YLDs, costs and prevalence of neurological conditions were generally not correlated across the eight countries. A clear North–South gradient was found for health expenditures, and partially for YLDs, costs and diseases' prevalence. We hypothesized that this is a consequence of the expansion of morbidity of neurological conditions connected to ageing, that health and welfare systems of selected countries were not prepared to face.
Source: Acta Neurologica Scandinavica - October 23, 2014 Category: Neurology Authors: A. Raggi, M. Leonardi Tags: Original Article Source Type: research

Depression, anxiety, and cognitive functioning after intracerebral hemorrhage
ConclusionsOne of four survivors of ICH at young age suffers long‐term PSD. Higher degree of disability predicted occurrence of PSD. Treatment of depression appears as an unmet need in young ICH survivors.
Source: Acta Neurologica Scandinavica - January 30, 2015 Category: Neurology Authors: R.‐J. Koivunen, H. Harno, T. Tatlisumak, J. Putaala Tags: Original Article Source Type: research

APOE and AGT in the Finnish p.Arg133Cys CADASIL population
ConclusionsThe APOE, AGT and NOTCH3 polymorphism did not modify the onset of strokes or migraine in our CADASIL sample, which is one of the largest mutationally homogenous CADASIL populations published to date. International collaboration, pooled analyses and genomewide approaches are warranted to identify the genetic factors that modify the highly variable CADASIL phenotype.
Source: Acta Neurologica Scandinavica - March 26, 2015 Category: Neurology Authors: M. Siitonen, K. Mykkänen, F. Pescini, S. Rovio, H. Kääriäinen, M. Baumann, M. Pöyhönen, M. Viitanen Tags: Clinical Commentary Source Type: research

Predicting risk of symptomatic intracerebral hemorrhage and mortality after treatment with recombinant tissue‐plasminogen activator using SEDAN score
ConclusionsHigher SEDAN score was associated with an increased risk of sICH and early mortality in this monocenter study.
Source: Acta Neurologica Scandinavica - May 29, 2015 Category: Neurology Authors: M. Al‐Khaled, B. Langner, T. Brüning Tags: Original Article Source Type: research

Apolipoprotein E polymorphism in aneurysmal subarachnoid haemorrhage in West Sweden
ConclusionsThe APOEε4 polymorphism has no major influence on risk of aSAH, the occurrence of CVS or long‐term neurological outcome after aSAH.
Source: Acta Neurologica Scandinavica - September 16, 2015 Category: Neurology Authors: L. Z. Csajbok, K. Nylén, M. Öst, K. Blennow, H. Zetterberg, P. Nellgård, B. Nellgård Tags: Original Article Source Type: research

The determination of copeptin levels helps management decisions among transient ischaemic attack patients
ConclusionsSerum copeptin could be an important prognostic biomarker to guide management decisions among TIA patients. Therefore, TIA patients with copeptin levels below 13.8 pmol/l and without LAA have an insignificant risk of 7‐day SR and could be managed on an outpatient basis.
Source: Acta Neurologica Scandinavica - October 17, 2015 Category: Neurology Authors: F. Purroy, I. Suárez‐Luis, S. Cambray, J. Farré, I. Benabdelhak, G. Mauri‐Capdevila, J. Sanahuja, A. Quílez, R. Begué, M. I. Gil, J. Molina‐Seguin, N. Torreguitart Tags: Original Article Source Type: research