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Source: BMJ Open

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Total 555 results found since Jan 2013.

Economic evaluation of endovascular treatment for acute ischaemic stroke in Thailand
Conclusions EVT represents good value for money in the Thai context, both when provided to patients eligible for intravenous alteplase, and when provided alone to those who are ineligible for intravenous alteplase.
Source: BMJ Open - September 27, 2022 Category: General Medicine Authors: Rattanavipapong, W., Worakijthamrongchai, T., Soboon, B., Luankongsomchit, V., Kongmuangpuk, M., Isaranuwatchai, W., Teerawattananon, Y., Nilanont, Y. Tags: Open access, Health economics Source Type: research

Coronary atherosclerotic burden assessed by SYNTAX scores and outcomes in surgical, percutaneous or medical strategies: a retrospective cohort study
Conclusions Coronary atherosclerotic burden alone was not associated with significantly increased risk of all-cause mortality. The SSII better discriminates the risk of death. Trial registration number ISRCTN66068876.
Source: BMJ Open - September 22, 2022 Category: General Medicine Authors: Scudeler, T. L., Farkouh, M. E., Hueb, W., Rezende, P. C., Campolina, A. G., Martins, E. B., Godoy, L. C., Soares, P. R., Ramires, J. A. F., Kalil Filho, R. Tags: Open access, Cardiovascular medicine Source Type: research

Myocardial infarction and stroke subsequent to urinary tract infection (MISSOURI): protocol for a self-controlled case series using linked electronic health records
Introduction There is increasing interest in the relationship between acute infections and acute cardiovascular events. Most previous research has focused on understanding whether the risk of acute cardiovascular events increases following a respiratory tract infection. The relationship between urinary tract infections (UTIs) and acute cardiovascular events is less well studied. Therefore, the aim of this study is to determine whether there is a causal relationship between UTI and acute myocardial infarction (MI) or stroke. Methods and analysis We will undertake a self-controlled case series study using linked anonymised ...
Source: BMJ Open - September 22, 2022 Category: General Medicine Authors: Reeve, N. F., Best, V., Gillespie, D., Hughes, K., Lugg-Widger, F. V., Cannings-John, R., Torabi, F., Wootton, M., Akbari, A., Ahmed, H. Tags: Open access, Infectious diseases Source Type: research

Effects of healthcare system transformations spurred by the COVID-19 pandemic on management of stroke and STEMI: a registry-based cohort study in France
Conclusions The pandemic did not markedly alter the functioning of the emergency network. Although stroke patient management deteriorated, the resilience of the STEMI pathway was linked to its stronger structuring. Transversal reorganisations, aiming at concentrating resources on emergency care, contributed to maintenance of the quality of care. Trial registration number NCT04979208.
Source: BMJ Open - September 21, 2022 Category: General Medicine Authors: Lesaine, E., Francis-Oliviero, F., Domecq, S., Bijon, M., Cetran, L., Coste, P., Lhuaire, Q., Miganeh-Hadi, S., Pradeau, C., Rouanet, F., Sevin, F., Sibon, I., Saillour-Glenisson, F., AVICOVID group, Faucheux, Leca Radu, Seignolles, Chazalon, Dan, Lucas, Tags: Open access, Public health, COVID-19 Source Type: research

Stand-Alone Left Atrial appendage occlusion for throMboembolism prevention in nonvalvular Atrial fibrillatioN DiseasE Registry (SALAMANDER): protocol for a prospective observational nationwide study
Introduction Atrial fibrillation (AF) is a prevalent disease considerably contributing to the worldwide cardiovascular burden. For patients at high thromboembolic risk (CHA2DS2-VASc ≥3) and not suitable for chronic oral anticoagulation, owing to history of major bleeding or other contraindications, left atrial appendage occlusion (LAAO) is indicated for stroke prevention, as it lowers patient’s ischaemic burden without augmentation in their anticoagulation profile. Methods and analysis Stand-Alone Left Atrial appendage occlusion for throMboembolism prevention in nonvalvular Atrial fibrillatioN DiseasE Registry (S...
Source: BMJ Open - September 21, 2022 Category: General Medicine Authors: Kowalewski, M., Wanha, W., Litwinowicz, R., Kołodziejczak, M., Pasierski, M., Januszek, R., Kuzma, Łukasz, Grygier, M., Lesiak, M., Kapłon-Cieslicka, A., Reczuch, K., Gil, R., Pawłowski, T., Bartus, K., Dobrzycki, S., Lorusso, Tags: Open access, Cardiovascular medicine Source Type: research

Health economic evaluation of the 'Flying Intervention Team as a novel stroke care concept for rural areas: study protocol of the TEMPiS-GÖA study
The objective of the present paper is to describe the methods for the economic evaluation (TEMPiS-Gesundheitsökonomische Analyse (TEMPiS-GÖA)) alongside the TEMPiS-FIT study to determine whether the new form of care is cost-effective compared with standard care. Methods and analysis The within-trial cost-effectiveness analysis (CEA) and cost–utility analysis (CUA) will be performed from a statutory health insurance perspective as well as from a societal perspective over the time horizon of 12 months after the patients’ hospital discharge. Direct costs from outpatient and inpatient care are coll...
Source: BMJ Open - September 20, 2022 Category: General Medicine Authors: Coors, M., Flemming, R., Schüttig, W., Hubert, G. J., Hubert, N. D., Sundmacher, L. Tags: Open access, Health economics Source Type: research

Age-dependent and sex-dependent differences in mortality from influenza-associated cardiovascular diseases among older adults in Shanghai, China: a population-based study
Conclusions Excess mortality rates for CVDs associated with influenza increased with age in older adults. The risk for influenza-associated IHD mortality was significantly higher in older women than men. Our findings will help implement targeted health strategies, including the promotion of influenza vaccination and early therapeutic intervention for the older population with CVD, to curb the influenza burden effectively.
Source: BMJ Open - September 19, 2022 Category: General Medicine Authors: Jin, S., Jiang, C., Xia, T., Gu, Z., Yu, H., Li, J., Zheng, Y., Pan, H., Qiao, J., Cai, R., Wu, H., Wang, C. Tags: Open access, Epidemiology Source Type: research

Experiences of patients who had a stroke and rehabilitation professionals with upper limb rehabilitation robots: a qualitative systematic review protocol
Introduction Emerging evidence suggests that robotic devices for upper limb rehabilitation after a stroke may improve upper limb function. For robotic upper limb rehabilitation in stroke to be successful, patients’ experiences and those of the rehabilitation professionals must be considered. Therefore, this review aims to synthesise the available evidence on experiences of patients after a stroke with rehabilitation robots for upper limb rehabilitation and the experiences of rehabilitation professionals with rehabilitation robots for upper limb stroke rehabilitation. Methods and analysis Database search will include...
Source: BMJ Open - September 19, 2022 Category: General Medicine Authors: Chockalingam, M., Vasanthan, L. T., Balasubramanian, S., Sriram, V. Tags: Open access, Qualitative research Source Type: research

Feasibility and acceptability of a mobile model of environmental enrichment for patients with mixed medical conditions receiving inpatient rehabilitation: a mixed methods study
Conclusions As interest grows in human EE models, it will be important to tailor EE interventions to the unique demands of hospital rehabilitation services. A mobile EE model delivered in a small, mixed rehabilitation ward appears feasible and acceptable to study in a larger controlled feasibility trial.
Source: BMJ Open - September 17, 2022 Category: General Medicine Authors: Fulton, S., Janssen, H., Salih, S., James, A., Elphinston, R. A. Tags: Open access, Rehabilitation medicine Source Type: research

Conditions associated with the initiation of domiciliary care following a hospital admission: a cohort study in East London, England
Conclusion Hospitals are a major referral route into domiciliary care. While patients admitted due to new and acute illnesses account for many domiciliary care packages, exacerbations of long-term conditions and age-related and frailty-related conditions are also important drivers.
Source: BMJ Open - September 15, 2022 Category: General Medicine Authors: Grimm, F., Lewer, D., Craig, J., Rogans-Watson, R., Shand, J. Tags: Open access, Health services research Source Type: research

Cluster randomised controlled trial of screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the pilot study for the SAFER trial
Introduction Atrial fibrillation (AF) is a common arrhythmia associated with 30% of strokes, as well as other cardiovascular disease, dementia and death. AF meets many criteria for screening, but there is limited evidence that AF screening reduces stroke. Consequently, no countries recommend national screening programmes for AF. The Screening for Atrial Fibrillation with ECG to Reduce stroke (SAFER) trial aims to determine whether screening for AF is effective at reducing risk of stroke. The aim of the pilot study is to assess feasibility of the main trial and inform implementation of screening and trial procedures. Metho...
Source: BMJ Open - September 9, 2022 Category: General Medicine Authors: Williams, K., Modi, R. N., Dymond, A., Hoare, S., Powell, A., Burt, J., Edwards, D., Lund, J., Johnson, R., Lobban, T., Lown, M., Sweeting, M. J., Thom, H., Kaptoge, S., Fusco, F., Morris, S., Lip, G., Armstrong, N., Cowie, M. R., Fitzmaurice, D. A., Free Tags: Open access, Public health Source Type: research

Burden of neurological diseases in Asia from 1990 to 2019: a systematic analysis using the Global Burden of Disease Study data
Conclusions This study demonstrated the burden of neurological diseases in Asia. To reduce the burden of neurological diseases, strategies suitable for each country’s real healthcare needs and challenges are needed; this study can serve as the cornerstone of these strategies.
Source: BMJ Open - September 7, 2022 Category: General Medicine Authors: Kang, S., Eum, S., Chang, Y., Koyanagi, A., Jacob, L., Smith, L., Shin, J. I., Song, T.-J. Tags: Open access, Epidemiology Source Type: research

Comparative efficacy of eight therapeutic methods in the treatment of left main coronary artery disease: a Bayesian network meta-analysis protocol
Introduction As for coronary artery bypass grafting, although there are many direct comparative studies on different minimally invasive methods and traditional thoracotomy (off-pump/on-pump), there is still a lack of further ranking and summary of the efficacy of all surgical methods for left main coronary artery (LMCA) lesions. Combined with the current controversial views, this study aims to introduce a planned network meta-analysis (NMA) in detail, with a view to comparing the long-term efficacy and safety of multiple therapeutic methods in the treatment of patients with LMCA disease, and finally providing some referenc...
Source: BMJ Open - September 6, 2022 Category: General Medicine Authors: Hou, B., Chen, M., Li, Q., Huang, W., Wang, L. Tags: Open access, Cardiovascular medicine Source Type: research

Accounts of preventative coping: an interview study of stroke survivors on general practice registers
Conclusions We highlight that coping was characterised by survivors as something enacted by the individual self, and consider how constructions of self may impact preventative coping efforts.
Source: BMJ Open - September 5, 2022 Category: General Medicine Authors: Scott Reid, P., Neville, E., Cater, F., Mullis, R., Mant, J., Duschinsky, R. Tags: Open access, Cardiovascular medicine Source Type: research

Economic impact of the first pass effect in mechanical thrombectomy for acute ischaemic stroke treatment in Spain: a cost-effectiveness analysis from the national health system perspective
Conclusion Achieving FPE after MT can lead to better health outcomes per AIS patient and important cost savings for the Spanish NHS.
Source: BMJ Open - September 1, 2022 Category: General Medicine Authors: Gonzalez Diaz, E., Rodriguez-Paz, C., Fernandez-Prieto, A., Martinez-Galdamez, M., Martinez-Moreno, R., Ortega Quintanilla, J., Tomasello, A., Zamarro, J., Liebeskind, D., Zaidat, O. O., Mueller-Kronast, N. H. Tags: Open access, Health economics Source Type: research