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Total 555 results found since Jan 2013.

Supportive care needs of patients who had a stroke: a scoping review protocol
Introduction Incidences of stroke are on the rise and approximately 80 million stroke survivors worldwide live with disabilities. Supportive care needs of stroke survivors are not adequately defined, and the assessment tools to help care service providers identify these needs are unclear. The overall aim of this scoping review will be to map the supportive care needs of stroke survivors against the Supportive Care Needs Framework. Methods and analysis This scoping review will be conducted following Arksey and O’Malley’s methodological framework and Joanna Briggs Institute (JBI) updated methodological guidance ...
Source: BMJ Open - August 24, 2023 Category: General Medicine Authors: Zhang, H., Xu, K., Ma, J. Y., Zhang, X. Y., Sun, Y. Y., Xiao, L. D., Yan, F., Luo, Y. Y., Tang, S. Tags: Open access, Health services research Source Type: research

Impact of areal socioeconomic status on prehospital delay of acute ischaemic stroke: retrospective cohort study from a prefecture-wide survey in Japan
Conclusions Living in socioeconomically disadvantaged municipalities was associated with prehospital delays of acute ischaemic stroke in non-capital areas in Kochi prefecture, Japan. Poorer outcomes of those patients may be caused by delayed treatment of intravenous rt-PA and endovascular reperfusion therapy. Further studies are necessary to determine social risk factors in the capital areas. Trial registration number This article is linked to a clinical trial to UMIN000050189, No.: R000057166 and relates to its Result stage.
Source: BMJ Open - August 24, 2023 Category: General Medicine Authors: Fukuda, H., Hyohdoh, Y., Ninomiya, H., Ueba, Y., Ohta, T., Kawanishi, Y., Kadota, T., Hamada, F., Fukui, N., Nonaka, M., Kawada, K., Fukuda, M., Nishimoto, Y., Matsushita, N., Nojima, Y., Kida, N., Hayashi, S., Izumidani, T., Nishimura, H., Moriki, A., Ue Tags: Open access, Neurology Source Type: research

Is a novel digital system for arm and hand rehabilitation suitable for stroke survivors? A qualitative process evaluation of OnTrack
Conclusions This process evaluation supported initial theoretical assumptions that OnTrack would enable activity practice through the use of remote monitoring. There was a strong emphasis on the coaching role as a mechanism of impact supporting the technological intervention. These findings will inform the next stages of delivery in a definitive trial. Trial registration number NCT03944486.
Source: BMJ Open - August 18, 2023 Category: General Medicine Authors: Taylor, E., Fusari, G., Darzi, A., Jones, F. Tags: Open access, Rehabilitation medicine Source Type: research

Screening over 100 000 patients in 39 general practices in the Netherlands for anticoagulation underprescription in atrial fibrillation: a descriptive, cross-sectional study
Conclusions In this large Dutch study among GPs, we observed 9.8% underprescription of OAC in AF patients. In 76% of the AF patients lacking a prescription for OAC, no documentation for deviating from the guidelines was found. Only in a minority of cases detection of OAC underprescription lead to OAC initiation.
Source: BMJ Open - August 18, 2023 Category: General Medicine Authors: Voorhout, L., Pisters, R., Geurts, C. H. P. H., Oostindjer, A., van Doorn, S., Rila, H., Fuijkschot, W. W., Verheugt, F., Hemels, M. E. W. Tags: Open access, Cardiovascular medicine Source Type: research

Effectiveness of acceptance and commitment therapy in patients who had a stroke: a systematic review protocol
This study aimed to systematically evaluate the intervention effect of ACT in patients who had a stroke, which may provide further clinical evidence. Methods and analysis A systematic search of databases, including CNKI, WanFang Data, VIP, CBM, PubMed, Embase, Cochrane Library, CINAHL and APA PsycArticles, will be conducted from their inception to 31 October 2022. All randomised controlled trials, quasi-experiments and case studies relevant to ACT will be included in English and Chinese. Two independent reviewers will conduct the review, with data extraction and quality evaluation. Review Manager V.5.4 will be used to ass...
Source: BMJ Open - August 17, 2023 Category: General Medicine Authors: Xu, K., Zhang, X. Y., Ma, J. Y., Guo, X., Zhu, S.-S., Zhang, H., Sun, Y. Y. Tags: Open access, Mental health Source Type: research

Exoskeletal wearable robot on ambulatory function in patients with stroke: a protocol for an international, multicentre, randomised controlled study
This study is an international, multicentre, randomised controlled study at five institutions with a total of 150 patients with subacute stroke. Participants will be randomised into two groups (75 patients in the robot-assisted gait training (RAGT) group and 75 patients in the control group). The gait training will be performed with a total of 20 sessions (60 min/session); 5 sessions a week for 4 weeks. The RAGT group will receive 30 min of gait training using an exoskeleton (ANGEL LEGS M20, Angel Robotics) and 30 min of conventional gait training, while the control group will receive 60 min conventional gait training. In ...
Source: BMJ Open - August 11, 2023 Category: General Medicine Authors: Chang, W. H., Kim, T.-W., Kim, H. S., Hanapiah, F. A., Kim, D. H., Kim, D. Y. Tags: Open access, Rehabilitation medicine Source Type: research

Cardiovascular effects of rivaroxaban in heart failure patients with sinus rhythm and coronary disease with and without diabetes: a retrospective international cohort study from COMMANDER-HF
Conclusions In COMMANDER-HF a diagnosis of diabetes conferred higher rates of cardiovascular events that, with exception of ischaemic stroke, was not substantially reduced by rivaroxaban. Rivaroxaban was associated with reduced risk of ischaemic stroke for patients with and without diabetes. Trial registration number NCT01877915; Post-results.
Source: BMJ Open - August 11, 2023 Category: General Medicine Authors: Sharma, A., Caldeira, D., Razaghizad, A., Pinto, F. J., van Veldhuisen, D. J., Mehra, M. R., Lam, C. S. P., Cleland, J., Anker, S. D., Greenberg, B., Ferreira, J. P., Zannad, F. Tags: Open access, Cardiovascular medicine Source Type: research

Integrative-interpersonal dynamic therapy for poststroke depression (INID): study protocol of a randomised controlled pilot trial
Introduction Depression is the most frequent psychiatric disorder following stroke, affecting about one-third of stroke survivors. Patients experience poorer recovery, lower quality of life and higher mortality compared with stroke survivors without depression. Despite these well-known malign consequences, poststroke depression (PSD) is regarded underdiagnosed and undertreated. Evidence of beneficial effects of psychotherapy to treat PSD remains scarce and inconclusive and is limited by heterogeneity in design, content and timing of the intervention. This pilot study aims to assess the feasibility of a newly developed inte...
Source: BMJ Open - August 8, 2023 Category: General Medicine Authors: Volz, M., Mundiyanapurath, S., Schauenburg, H., Meuth, S. G., Wild, B., Werheid, K., Barber, J. P., Schäfer, R., Beerbaum, L., Dinger, U. Tags: Open access, Rehabilitation medicine Source Type: research

Perspectives of cardiac rehabilitation in patients who had a stroke: a protocol for a qualitative study review
Introduction Stroke has a high incidence and disability rate, and its recurrence and readmission rates are rising, making it the second-leading cause of mortality in the globe. Cardiac rehabilitation is a well-known, evidence-based strategy that might serve as an additional preventative programme. Prior quantitative research has proven the positive results and high practicability of cardiac rehabilitation for patients who had a stroke, however, cardiac rehabilitation is not yet a routine component of stroke rehabilitation worldwide. It might be useful to conduct meta-integration of previous qualitative studies to understan...
Source: BMJ Open - August 3, 2023 Category: General Medicine Authors: Jiang, H., Mei, Y., Lin, B., Wang, W., Wang, X., Zhao, Z., Zhang, Z.-x. Tags: Open access, Neurology Source Type: research

Multicohort cross-sectional study of cognitive and behavioural digital biomarkers in neurodegeneration: the Living Lab Study protocol
Introduction and aims Digital biomarkers can provide a cost-effective, objective and robust measure for neurological disease progression, changes in care needs and the effect of interventions. Motor function, physiology and behaviour can provide informative measures of neurological conditions and neurodegenerative decline. New digital technologies present an opportunity to provide remote, high-frequency monitoring of patients from within their homes. The purpose of the living lab study is to develop novel digital biomarkers of functional impairment in those living with neurodegenerative disease (NDD) and neurological condi...
Source: BMJ Open - August 3, 2023 Category: General Medicine Authors: Crook-Rumsey, M., Daniels, S. J. C., Abulikemu, S., Lai, H., Rapeaux, A., Hadjipanayi, C., Soreq, E., Li, L. M., Bashford, J., Jeyasingh-Jacob, J., Gruia, D. C., Lambert, D., Weil, R., Hampshire, A., Sharp, D. J., Haar, S. Tags: Open access, Neurology Source Type: research

Barriers and facilitators in providing home-based rehabilitation for stroke survivors with severe disability in the UK: an online focus group study with multidisciplinary rehabilitation teams
Conclusions Collaboration and partnership working is important in the delivery of rehabilitation for stroke survivors with severe disability. Commissioners need to be aware that cross-agency multidisciplinary expertise is required, if rehabilitation opportunities are to be realised and existing health inequalities addressed.
Source: BMJ Open - August 2, 2023 Category: General Medicine Authors: Fisher, R. J., Russell, L., Riley-Bennett, F., Cameron, T., Walker, M., Sackley, C. Tags: Open access, Rehabilitation medicine Source Type: research

Bedtime versus morning use of antihypertensives in frail continuing care residents (BedMed-Frail): protocol for a prospective, randomised, open-label, blinded end-point pragmatic trial
Introduction BedMed-Frail explores risks and benefits of switching antihypertensives from morning to bedtime in a frail population at greater risk of hypotensive adverse effects. Methods and analysis Design: Prospective parallel randomised, open-label, blinded end-point trial. Participants: Hypertensive continuing care residents, in either long-term care or supportive living, who are free from glaucoma, and using ≥1 once daily antihypertensive. Setting: 16 volunteer continuing care facilities in Alberta, Canada, with eligible residents identified using electronic health claims data. Intervention: All non-opted out elig...
Source: BMJ Open - August 1, 2023 Category: General Medicine Authors: Garrison, S. R., Youngson, E., Perry, D. A., Campbell, F. N., Kolber, M. R., Korownyk, C., Allan, G. M., Green, L., Bakal, J. Tags: Open access, Cardiovascular medicine Source Type: research

Trends of frequency, mortality and risk factors among patients admitted with stroke from 2017 to 2019 to the medical ward at Kilimanjaro Christian Medical Centre hospital: a retrospective observational study
Conclusion The burden of stroke on individuals and health services is increasing over time, which reflects a lack of awareness on the cause of stroke and effective preventive measures. Prioritising interventions directed towards the reduction of non-communicable diseases and associated complications, such as stroke, is urgently needed.
Source: BMJ Open - July 31, 2023 Category: General Medicine Authors: Moshi, B., Yongolo, N., Biswaro, S. M., Maro, H., Linus, S., Siebert, S., Nkenguye, W., McIntosh, E., Shirima, F., Njau, R. E., Andongolile, A. A., Mwanswila, M. J., Halliday, J. E. B., Krauth, S., Kilonzo, K., Walker, R. W., Temu, G. A., Mmbaga, B. T. Tags: Open access, Cardiovascular medicine Source Type: research

Distinct cardiovascular and cancer burdens associated with social position, work environment and unemployment: a cross-sectional and retrospective study in a large population-based French cohort
Conclusions Social position, work environment and unemployment are associated with distinct cardiovascular and cancerous diseases that could add up during lifetime, they should therefore be considered all together in any preventive strategy.
Source: BMJ Open - July 31, 2023 Category: General Medicine Authors: Sanchez Rico, M., Plessz, M., Airagnes, G., Ribet, C., Hoertel, N., Goldberg, M., Zins, M., Meneton, P. Tags: Open access, Epidemiology Source Type: research

Optokinetic stimulation effects in the management of unilateral spatial neglect in patients with chronic stroke: study protocol for a randomised controlled trial
This study has been approved by the Ethics Committee University of Salamanca on February 2020 (registration number: 584). All patients in the study will be informed about the objective of the study and will give their written informed consent to participate in the study. The anonymised database will be available from the publication of the results for 10 years in the repository of the University of Salamanca GREDOS (https://gredos.usal.es/). The trial results will be shared with the scientific community at international conferences and by publication in a peer-reviewed journal. Trial registration number NCT04663646.
Source: BMJ Open - July 30, 2023 Category: General Medicine Authors: Perez-Robledo, F., Sanchez Gonzalez, J. L., Bermejo-Gil, B. M., Llamas-Ramos, R., Martin-Nogueras, A. M. Tags: Open access, Neurology Source Type: research