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Total 50 results found since Jan 2013.

Clinical trial participant ’s autopsy and brain exam stoke Alzheimer’s drug fears
A full autopsy and detailed examination of the brain of a 79-year-old Florida woman who died after receiving lecanemab, an experimental Alzheimer’s therapy, in a pivotal clinical trial has deepened some researchers’ concerns that it poses serious risks for patients who share the woman’s hard-to-diagnose, preexisting condition. The patient’s history and autopsy “strongly suggests that lecanemab infusions were a catalyst leading to the events resulting in her death,” says Vanderbilt University pathologist Hannah Harmsen, co-author of a recently completed case report, which Science has obtained. The aut...
Source: Science of Aging Knowledge Environment - April 13, 2023 Category: Geriatrics Source Type: research

The 5 Best Ways to Control High Cholesterol, According to People With the Condition
There are a variety of factors that influence cardiovascular risk—but cholesterol is one of the first things that doctors pay attention to. Having high levels of low-density lipoprotein (LDL) cholesterol is “definitely a variable we try to manage, because it’s been shown to be problematic for heart health,” says Dr. Adriana Quinones-Camacho, a cardiologist at NYU Langone Health. Though it’s often called the “bad” kind of cholesterol, LDL cholesterol makes up most of your body’s cholesterol stores. That means it’s not a villain on its own, but when levels start creeping ...
Source: TIME: Health - January 18, 2023 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized healthscienceclimate heart health Source Type: news

Scientists tie third clinical trial death to experimental Alzheimer ’s drug
As enthusiasm mounts for a new experimental antibody that appears to slow cognitive decline in some Alzheimer’s patients, a third death linked to the drug during its clinical testing may amplify concerns about its safety. Science has obtained medical records showing a 79-year-old Florida woman participating in an ongoing trial of the antibody died in mid-September after experiencing extensive brain swelling and bleeding, as well as seizures. Multiple neuroscientists who reviewed the records at Science ’s request believe her death was likely caused by the antibody, lecanemab. “The brain swelling and t...
Source: ScienceNOW - December 21, 2022 Category: Science Source Type: news

Second death linked to potential antibody treatment for Alzheimer ’s disease
A 65-year-old woman who was receiving a promising experimental treatment to slow the cognitive decline caused by her early Alzheimer’s disease recently died from a massive brain hemorrhage that some researchers link to the drug. The clinical trial death, described in an unpublished case report Science has obtained, is the second thought to be associated with the antibody called lecanemab. The newly disclosed fatality intensifies questions about its safety and how widely lecanemab should be prescribed if ultimately approved by regulators. The woman, who received infusions of the antibody as part of the trial, s...
Source: ScienceNOW - November 28, 2022 Category: Science Source Type: news

Clinical perspectives and strategies for confronting disparities in social determinants of health for Hispanic bilinguals with aphasia
J Commun Disord. 2022 Jun 3;98:106231. doi: 10.1016/j.jcomdis.2022.106231. Online ahead of print.ABSTRACTDisparities in social determinants of health (SDOH) such as socioeconomic status and access to quality healthcare present serious barriers to enrollment in clinical rehabilitation programs for individuals who have experienced a stroke, especially for those who identify with a racial-ethnic minority group. Hispanic bilinguals with aphasia (HBWA) are one marginalized group who face even greater enrollment challenges since post-stroke language impairment and limited English proficiency make it difficult to advocate for one...
Source: Journal of Communication Disorders - June 10, 2022 Category: Speech-Language Pathology Authors: Michael Scimeca Fatemeh Abdollahi Claudia Pe ñaloza Swathi Kiran Source Type: research

What It ’s Like Living With Aphasia—and How to Support a Loved One With the Condition
Bruce Willis, the 67-year-old actor and star of classic action movies like Die Hard, is halting his acting career after being diagnosed with the language disorder aphasia. On March 30, his daughter Rumer, ex-wife Demi Moore, and other family members announced the diagnosis on Instagram. “Our beloved Bruce has been experiencing some health issues and has recently been diagnosed with aphasia, which is impacting his cognitive abilities,” the family wrote. “As a result of this and with much consideration Bruce is stepping away from the career that has meant so much to him.” [time-brightcove not-tgx=R...
Source: TIME: Health - March 31, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized healthscienceclimate medicine Source Type: news

Ditching cigarettes for smokeless tobacco can help cut cardiovascular risks, study finds
Regular smokers are at heightened risk of developing cardiovascular disease, but crushing the butts in favor of a “smokeless” alternative like chewing tobacco, snuff or tobacco lozenges may go a long way toward bringing the danger down to a more normal level, a new UCLA-led study shows.The findings also indicate that the primary culprit in smokers ’ increased risk is not nicotine but other chemicals found in tobacco smoke. Both cigarettes and smokeless tobacco products contain large quantities of nicotine.The study,published today in the journal Nicotine and Tobacco Research, involved a team of researchers from UCLA...
Source: UCLA Newsroom: Health Sciences - January 6, 2022 Category: Universities & Medical Training Source Type: news

Computer simulations of the brain can predict language recovery in stroke survivors
(Boston University) Speech rehabilitation experts can predict how well a patient will recover from aphasia, a disorder caused by damage to the part of the brain responsible for producing language.
Source: EurekAlert! - Medicine and Health - June 4, 2021 Category: International Medicine & Public Health Source Type: news

Opportunities to better detect, manage and treat patients with undiagnosed atrial fibrillation
(Boston University School of Medicine) Atrial fibrillation (AF) is associated with a higher risk of complications including ischemic stroke, cognitive decline, heart failure, myocardial infarction and death. AF frequently is undetected until complications such as stroke or heart failure occur. A new report led by Boston University School of Medicine (BUSM) researcher Emelia J. Benjamin, MD, ScM, builds upon a recently conducted National Heart, Lung, and Blood Institute's virtual workshop that focused on identifying key research priorities related to AF screening.
Source: EurekAlert! - Medicine and Health - January 25, 2021 Category: International Medicine & Public Health Source Type: news

Early Postoperative Functional Assessment Predicts Non-home Discharge following Pulmonary Lobectomy.
CONCLUSIONS: Early postoperative functional impairment assessment using AM-PAC may be useful to predict of non-hospital discharge following pulmonary lobectomy. Attention to these factors may be used to aid early disposition planning, and adjust preventative strategies. PMID: 32891652 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 2, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Power AD, Merritt RE, Patterson K, Abdel-Rasoul M, D'Souza D, Fitzgerald M, Moffatt-Bruce SD, Kneuertz PJ Tags: Ann Thorac Surg Source Type: research

Soft robotic exosuit makes stroke survivors walk faster and farther
(Wyss Institute for Biologically Inspired Engineering at Harvard) Using an untethered version of their soft exosuit that carries its own battery and motor, Harvard and Boston University researchers showed in a cohort of six post-stroke survivors with hemiparesis that their device could significantly increase individuals' walking speed by an average 0.14 meters per second. These same individuals, when asked to walk as far as they can in 6 minutes, were able to go 32 meters farther, on average.
Source: EurekAlert! - Medicine and Health - May 11, 2020 Category: International Medicine & Public Health Source Type: news

Greater Long-Term Decline in Stroke Seen Among Older Adults
MONDAY, June 24, 2019 -- The decline in midlife ischemic strokes over time is less pronounced than the decline among older adults, according to a study published in the June issue of Stroke. Hugo J. Aparicio, M.D., from Boston University, and...
Source: Drugs.com - Pharma News - June 24, 2019 Category: Pharmaceuticals Source Type: news

Heart failure, stroke greater among occupants in motor vehicle accidents
(Boston University School of Medicine) New research has shown that in older adults (65 and older), being an occupant in an automobile during a motor vehicle accident may lead to heart failure or stroke, as compared to pedestrians who are involved in motor vehicle accidents.
Source: EurekAlert! - Medicine and Health - May 23, 2019 Category: International Medicine & Public Health Source Type: news

Long-term decline in stroke greater in older adults
(Boston University School of Medicine) Although the occurrence of first-ever ischemic stroke (strokes due to a blood clot that blocks a blood vessel in the brain) at middle age has been decreasing over time, researchers have found that the decline is not as steep as seen in older adults.
Source: EurekAlert! - Medicine and Health - May 16, 2019 Category: International Medicine & Public Health Source Type: news

Balloon-guided catheters provide better blood flow following stroke interventions
(Boston University School of Medicine) Patients who have experienced a stroke as a result of blockages of the arteries in the brain have better outcomes with the use of balloon-guided catheter surgery as compared to having a conventional guided catheter procedure.
Source: EurekAlert! - Medicine and Health - February 4, 2019 Category: International Medicine & Public Health Source Type: news