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Management: National Institute for Health Research (NIHR)

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Total 9 results found since Jan 2013.

Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy
CONCLUSION. Our findings uncover a major cause of sporadic VMs of different clinical types and thereby offer the potential of personalized medical treatment by repurposing existing licensed cancer therapies. FUNDING. This work was funded or supported by grants from the AVM Butterfly Charity, the Wellcome Trust (UK), the Medical Research Council (UK), the UK National Institute for Health Research, the L’Oreal-Melanoma Research Alliance, the European Research Council, and the National Human Genome Research Institute (US).
Source: Journal of Clinical Investigation - March 12, 2018 Category: Biomedical Science Authors: Lara Al-Olabi, Satyamaanasa Polubothu, Katherine Dowsett, Katrina A. Andrews, Paulina Stadnik, Agnel P. Joseph, Rachel Knox, Alan Pittman, Graeme Clark, William Baird, Neil Bulstrode, Mary Glover, Kristiana Gordon, Darren Hargrave, Susan M. Huson, Thomas Source Type: research

Heat-Related Mortality in Japan after the 2011 Fukushima Disaster: An Analysis of Potential Influence of Reduced Electricity Consumption
Conclusions: In the prefectures with the greatest reductions in electricity consumption, heat-related mortality decreased rather than increased following the Great East Japan Earthquake. Additional research is needed to determine whether this finding holds for other populations and regions, and to clarify its implications for policies to reduce the consequences of climate change on health. https://doi.org/10.1289/EHP493 Received: 11 May 2016 Revised: 07 March 2017 Accepted: 13 March 2017 Published: 06 July 2017 Address correspondence to M. Hashizume, Dept. of Pediatric Infectious Diseases, Institute of Tropical Medic...
Source: EHP Research - July 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Microglial activation in recent ischemic stroke: comparison of two TSPO tracers
Conclusion: The apparent intensity of microglial activation in ischemic stroke is closely comparable between 18F-GE180 and 11C-(R)-PK11195 PET. Research Support: The study is funded by a grant from NIHR and supported by GEHC and INMIND (EC FP7).
Source: Journal of Nuclear Medicine - May 24, 2017 Category: Nuclear Medicine Authors: Herholz, K., Hinz, R., Visi, E., Trigg, W., McDonald, K., Punter, M., Majid, A., Gerhard, A. Tags: Neurology Posters Source Type: research

The Stroke Prevention Programme: a programme of research to inform optimal stroke prevention in primary care, Programme Grants for Applied Research, Vol:4, Iss:3
Authors: Fletcher K, Mant J, McManus R, Hobbs R.
Source: NIHR Journals Library - April 1, 2016 Category: Global & Universal Source Type: research

Identifying Continence OptioNs after Stroke (ICONS): an evidence synthesis, case study and exploratory cluster randomised controlled trial of the introduction of a systematic voiding programme for patients with urinary incontinence after stroke in secondary care, Programme Grants for Applied Research, Vol:3, Iss:1
Authors: Thomas LH, French B, Sutton CJ, Forshaw D, Leathley MJ, Burton CR, Roe B, Cheater FM, Booth J, McColl E, Carter B, Walker A, Brittain K, Whiteley G, Rodgers H, Barrett J, Watkins CL on behalf of the ICONS project team and the ICONS patient, public and carer involvement groups
Source: NIHR Journals Library - March 18, 2015 Category: Global & Universal Source Type: research

Development and evaluation of tools and an intervention to improve patient- and carer-centred outcomes in Longer-Term Stroke care and exploration of adjustment post stroke: the LoTS care research programme, Programme Grants for Applied Research, Vol:2, Iss:6
Authors: Forster A, Mellish K, Farrin A, Bhakta B, House A, Hewison J, Murray J, Patel A, Knapp M, Breen R, Chapman K, Holloway I, Hawkins R, Shannon R, Nixon
Source: NIHR Journals Library - December 25, 2014 Category: Global & Universal Source Type: research

New hope for stroke survivors with NHS robot research
A major new NIHR-funded study using robot assisted training to help NHS stroke patients regain movement in their affected arm, has been officially launched today.Led by stroke specialists at Northumbria Healthcare NHS Foundation Trust, with researchers at Newcastle University and other UK institutions, the research grant from the NIHR HTA Programme will see NHS...
Source: NIHR Evaluation, Trials and Studies News - July 2, 2014 Category: American Health Source Type: news

Statins side effects are minimal, study argues
ConclusionThis meta-analysis pooled results from 29 studies and has shown a very small increased risk of newly diagnosed diabetes mellitus. This is the same as the decreased risk of any cause of death in people taking statins, compared to placebo, to prevent a heart attack or stroke.The researchers point out some limitations to the meta-analysis: Each study did not report on all of the side effects, meaning that for each category of side effect, the number of participants differed. The side effect categories were only included if at least 500 people had reported suffering from it. This means there may be numerous other si...
Source: NHS News Feed - March 13, 2014 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news