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Anticoagulation strategies in COVID-19 infected patients receiving ECMO support
CONCLUSION: In hospitalized patients with COVID-19-associated acute respiratory distress syndrome (ARDS) on VV ECMO support, the use of bivalirudin showed to be a viable anticoagulation alternative in terms of efficacy compared to UFH and resulted in a favorable safety profile with lower rates of bleeding and thrombotic events.PMID:37682210 | DOI:10.1051/ject/2023027
Source: Journal of Extra-Corporeal Technology - September 8, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Dayne Diaz Jenny Martinez Grant Bushman William R Wolowich Source Type: research

Introduction
This online supplement is the first of three featuring previously accepted manuscripts focusing on ischemic stroke. The last decade has witnessed a revolution in the endovascular management of acute ischemic stroke. Device improvement, better-constructed prospective trials, and refinements in endovascular techniques have sparked this revolution. However, critical issues still need to be addressed. Specifically, the importance of pre-thrombectomy imaging, medium-sized vessel thromboses, patient access to capable treatment centers, management of intracranial atherosclerosis, and posterior circulation disease are subjects of ...
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Albuquerque, F. C. Tags: Editorial Source Type: research

Consensus statement for the management of incidentally found brain white matter hyperintensities in general medical practice
Med J Aust. 2023 Aug 21. doi: 10.5694/mja2.52079. Online ahead of print.ABSTRACTINTRODUCTION: There is a paradigm shift in our understanding of white matter hyperintensities (WMH) found on brain imaging. They were once thought to be a normal phenomenon of ageing and, therefore, warranted no further investigation. However, evidence now suggests these lesions are markers of poor brain and cardiovascular health, portending an increased risk of stroke, cognitive decline, depression and death. Nevertheless, no specific guidelines exist for the management of incidentally found WMH for general medical practitioners and other clin...
Source: Med J Aust - August 21, 2023 Category: General Medicine Authors: Thomas P Ottavi Elizabeth Pepper Grant Bateman Mark Fiorentino Amy Brodtmann Source Type: research

O07/69 Procedural, clinical and safety outcomes in acute ischemic stroke stratified by operator techniques and clot location - insights from the assist registry
ConclusionASSIST provides insights into the effectiveness and safety of different MT techniques as stratified by clot location to improve reperfusion rates, functional outcomes and quality of life for AIS patients worldwide.ClinicalTrialsgov ID: NCT03845491Disclosure of InterestDFV reports consultancy for Medtronic, paid lectures for Cerenovus, and a research grant by MicroVention (unrelated to this work). DSL is a consultant as imaging core lab for Cerenovus, Genentech, Medtronic, Rapid Medical, Stryker, Vesalio. LLP is a Principal Biostatistician employed by Stryker Neurovascular. All other authors report no disclosures.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Moehlenbruch, M. A., Vollherbst, D., Miralbes, S., Naravetla, B., Spiotta, A., Loehr, C., Galdamez, M. M., Mctaggart, R., Defreyne, L., Vega, P., Zaidat, O., Price, L. L., Liebeskind, D., Gupta, R. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

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