Statins side effects are minimal, study argues

ConclusionThis meta-analysis pooled results from 29 studies and has shown a very small increased risk of newly diagnosed diabetes mellitus. This is the same as the decreased risk of any cause of death in people taking statins, compared to placebo, to prevent a heart attack or stroke.The researchers point out some limitations to the meta-analysis: Each study did not report on all of the side effects, meaning that for each category of side effect, the number of participants differed. The side effect categories were only included if at least 500 people had reported suffering from it. This means there may be numerous other side effects that were not covered by this research. New onset diabetes was only documented in 3 of the 29 trials, though the numbers were still reasonably large. Many trials do not state clearly how and how often adverse events were assessed. This is particularly important, as it is not clear from this type of analysis how often the side effects were experienced or the severity. Side effects not covered by this review include memory problems, blurred vision, ringing in the ears and skin problems.Anecdotally, muscle aches or weakness is one of the main reasons people stop taking statins. In this review, the category for muscle weakness was only looked at if the person also had a 10-fold increase in creatinine kinase level (indicating muscle damage). Muscle aches were separately recorded, as this is more common and not always experienced alongside muscle we...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

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Publication date: 1 March 2019Source: Personality and Individual Differences, Volume 139Author(s): Kostas A. Papageorgiou, Foteini-Maria Gianniou, Paul Wilson, Giovanni B. Moneta, Delfina Bilello, Peter J. CloughAbstractPrevious research reported that Subclinical Narcissism (SN) may increase Mental Toughness (MT) resulting in positive outcomes such as lower psychopathy, higher school grades and lower symptoms of depression. We conducted three studies (N = 364, 240 and 144 for studies 1, 2 and 3, respectively) to test a mediation model, which suggests that SN may increase MT predicting lower Perceived Stress (PS). The p...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
Conclusions: Although IAHA for the treatment of OA provided short-term efficiency, it had no effects on anxiety and increased depression of geriatric people. Health education should be provided with caution before viscosupplementation treatment to manage expectations of the efficacy of treatment for geriatric OA patients.ResumenAntecedentes/objetivo: La artrosis de rodilla (AR) en personas mayores puede causar ansiedad y depresión. Se investiga el efecto de la inyección intra-articular de ácido hialurónico (IAAH) en pacientes mayores con AR. Método: Ciento dos pacientes mayores tratados c...
Source: International Journal of Clinical and Health Psychology - Category: Psychiatry & Psychology Source Type: research
Abstract Pain is a significant problem in stable chronic obstructive pulmonary disease (COPD) and is associated with other symptoms, worse health status and lower functional status. Not much is known about pain in unstable disease. The primary aim of the present study is to investigate prevalence, characteristics and relationships of pain in patients with COPD hospitalized for an acute exacerbation (AECOPD) and indicated for post-acute pulmonary rehabilitation (PR). This cross-sectional observational study included 149 patients (mean age 70.8 (±7.9) years, 49% male, mean forced expiratory volume in one seco...
Source: Chronic Respiratory Disease - Category: Respiratory Medicine Authors: Tags: Chron Respir Dis Source Type: research
This study investigated the relationship of American Indian boarding school attendance and chronic physical health. We hypothesized boarding school attendance would be associated with an increased number of chronic physical health problems. We also examined the relationship between boarding school attendance and the 15 chronic health problems that formed the count of the chronic health conditions. American Indian attendees had a greater count of chronic physical health problems compared with nonattendees. Father's attendance was independently associated with chronic physical health problems. Attendees were more likely to h...
Source: Family and Community Health - Category: Primary Care Tags: Health Equity Source Type: research
CONCLUSIONS: We believe that computer-assisted 3D corrective osteotomy using prefabricated bone graft substitute achieved good results because it worked as a guide to the accurate angle. PMID: 30428808 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
CONCLUSIONS: Active patients, under 65 years of age with Eaton-Littler stage III osteoarthritis of the thumb CMC joint who are treated with anatomic pyrolytic carbon resurfacing hemiarthroplasty and stabilisation may achieve sustained improvement in pain and hand function for up to 6.5 years. PMID: 30428807 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
Abstract Corrective osteotomy with callus filling at fracture site for malunion after distal radius fracture is a rare technique, but it achieved a favorable postoperative outcome. The patient, 66-year-old female, visited our hospital 4 months after distal radius fracture. Corrective osteotomy of the distal radius was planned aiming at improving the wrist joint function, and was performed using a volar locking plate, then the bone defect was filled with callus as autogenous bone grafting. At 12 months after surgery, left wrist joint pain and the range of motion have improved, and the Mayo wrist score was excellent...
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
We report two rare cases of existing or worsening symptoms due to Kienböck's disease after distal radius fracture (DRF). During examination, radiographs show changes in the lunate bone; there was persistent wrist pain after treatment for DRF. In each case, surgeries were performed: A combined therapy (bone marrow transfusion, bone peg graft, external fixation, and low intensity pulsed ultrasound) for one, as well as carpal coalition for another. The etiology of these case presentations suggest that a compression fracture of the lunate due to a DRF resulted in softening and sclerosis. PMID: 30428800 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
CONCLUSIONS: Splinting provides symptomatic improvement in mild-to-moderate CTS and this study suggests that the wrist anthropometric measurements may influence treatment outcomes. PMID: 30428797 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
CONCLUSIONS: The BBTI technique is a surgical option that incorporates an interference screw, offering good functional results for managing osteoarthritis of the thumb carpometacarpal joint, with a similar complication rate to that of the original technique. PMID: 30428794 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
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