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Total 64 results found since Jan 2013.

World Stroke Organization Global Stroke Services Guidelines and Action Plan
Every two seconds, someone across the globe suffers a symptomatic stroke. ‘Silent’ cerebrovascular disease insidiously contributes to worldwide disability by causing cognitive impairment in the elderly. The risk of cerebrovascular disease is disproportionately higher in low to middle income countries where there may be barriers to stroke care. The last two decades have seen a major transformation in the stroke field with the emergence of evidence‐based approaches to stroke prevention, acute stroke management, and stroke recovery. The current challenge lies in implementing these interventions, particularly in regions ...
Source: International Journal of Stroke - September 23, 2014 Category: Neurology Authors: Patrice Lindsay, Karen L. Furie, Stephen M. Davis, Geoffrey A. Donnan, Bo Norrving Tags: Guidelines Source Type: research

A multi-modal approach to quality improvement: reducing 'door-to-ct' time in potenitally thombolysable stroke patients
Conclusion Early thrombolysis has been shown to improve outcomes in patients with ischaemic stroke.2 Reducing ‘Door-to-CT' scan time in the ED is an important step in enabling a reduction in the overall DTN time. This can be achieved by stream-lining key processes in the patient journey through the ED. A multi-modal approach ensured this change was introduced safely and effectively whilst re-enforcing a core change to standard working practice. Further work on process mapping and the delivery of thrombolysis is the next obvious step in further reduction in DTN time. Figure 1Quality Improvement Run Chart 'Door-t...
Source: Emergency Medicine Journal - November 17, 2016 Category: Emergency Medicine Authors: Waterson, F., Braithwaite, I., Tuck, I., Alcock, R. Tags: Stroke, Radiology, Clinical diagnostic tests, Radiology (diagnostics) RCEM Lightning presentations Source Type: research

Multidisciplinar Team Ability to Decrease Door-To-Needle Time in Acute Ischemic Stroke - A Single Center Saudi Experience (P6.053)
Conclusions: Implementation of modified stroke code process utilizing quality improvement paradigm of PDSA cycles have resulted in significant decrease in door-to-needle time for IV thrombolysis. Although, the target DTN of 60 minutes was not reached, the trend is favorable with improved outcomes. Disclosure: Partly presented at 5th Annual KAIMRC Forum, September, 2014, Jeddah, Saudi ArabiaDisclosure: Dr. Khatri has nothing to disclose. Dr. Khathaami has nothing to disclose. Dr. Alhamouieh has nothing to disclose. Dr. Abulaban has nothing to disclose. Dr. Scriven has nothing to disclose. Dr. Tarawneh has nothing to disclos...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khatri, I., Khathaami, A., Alhamouieh, O., Abulaban, A., Scriven, S., Tarawneh, M., Alrasheed, D., AlSomali, S., Catangui, E., Manalili, C., Ghadalla, A., Alanizi, A., Kojan, S. Tags: Prehospital Stroke Care and Uses of NIHSS Source Type: research

Quality Improvement Project: Improving the Time To Treatment in Inpatient Acute Ischemic Stroke (P7.130)
Conclusion/Proposal: In the inpatient setting there was a significant delay in the time to CT-scan and to t-PA; the main source of delay was time to CT-scan. There are many possible reasons for the delay: location of the CT-scanner, unfamiliarity with strokes by non-neurology staff, ready availability of t-PA. We proposed to target house staff education and t-PA availability. We developed a "stroke-code" checklist to be distributed to house staff from different services after a small explanatory lecture. We also developed an order form to create a zero wait time for t-PA, allowing the RN/PCA to be the first one served in t...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Liang, J., Garcia Santibanez, R., Walker, A., Boniece, I. Tags: Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course
Conclusions: Frequency of hemorrhagic transformation in Routine follow-up brain imaging and consecutive changes in therapeutic management were different depending on clinical course measured by NHISS score. Introduction Brain imaging 24–36 h after systemic thrombolysis for acute ischemic stroke is recommended in American Stroke Association and European Stroke Organization guidelines (1, 2). Brain imaging is performed to detect secondary bleeding or hemorrhagic transformation in order to adapt medical stroke prevention if necessary. Guideline recommendations are based on the results of the first study on rt-PA...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Age and gender differences in acute stroke hospital patients.
In conclusion, considerable differences were established between age and gender stroke patient groups, confirming the need of permanent national stroke registry and subsequent targeted action in secondary care, and prevention with education on risk factors, preferably personally tailored. PMID: 27333721 [PubMed - in process]
Source: Acta Clinica Croatica - June 24, 2016 Category: Journals (General) Tags: Acta Clin Croat Source Type: research

Stroke Triage: EMS needs a diagnostic tool that goes beyond a simple history & physical exam
As a young EMT and paramedic, I had relatively little education about acute myocardial infarctions. In the age of the 3-lead ECG, education was largely focused on arrhythmia detection and how to differentiate heart blocks, tachycardia and bradycardia. Detection of heart attack was largely based upon history and physical exam findings. Three decades later, the thought of relying on a physical exam to diagnose a ST- elevation myocardial infarction (STEMI) is hard to imagine. Although we’ve made remarkable progress in the prehospital detection of STEMI, we’ve made significantly less progress in the diagnosis of acute stro...
Source: JEMS Patient Care - May 2, 2018 Category: Emergency Medicine Authors: Mark E.A. Escott, MD, MPH, FACEP, NRP Tags: Patient Care Columns Source Type: news

A Prospective Stroke Register in Sierra Leone: Demographics, Stroke Type, Stroke Care and Hospital Outcomes
This study reports the demographics, stroke types, stroke care and hospital outcomes for stroke in Freetown, Sierra Leone.Methods: A prospective observational register recorded all patients 18 years and over with stroke between May 2019 and April 2020. Stroke was defined according to the WHO criteria. Pearson's chi-squared test was used to examine associations between categorical variables and unpaired t-tests for continuous variables. Multivariable logistic regression, to explain in-hospital death, was reported as odds ratios (ORs) and 95% confidence intervals.Results: Three hundred eighty-five strokes were registered, an...
Source: Frontiers in Neurology - September 7, 2021 Category: Neurology Source Type: research

Calcium supplements linked to post-stroke dementia in women
Conclusion The media paint this as a troubling study for older women who take calcium to strengthen their bones. However the small size of the study (only 98 women took calcium supplements, and only 14 of those got dementia) and its observational nature mean that we cannot rely on the results. As the researchers mention, it is possible that those taking supplements were less healthy than those that didn't in some unmeasured way. Further research may improve our confidence in these results. Broken bones are not a trivial matter for older people – a broken hip can be the difference between being able to live independentl...
Source: NHS News Feed - August 18, 2016 Category: Consumer Health News Tags: Neurology Medication Older people Source Type: news

Diagnosis of Acute Stroke.
Abstract Stroke can be categorized as ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage. Awakening with or experiencing the abrupt onset of focal neurologic deficits is the hallmark of the diagnosis of ischemic stroke. The most common presenting symptoms of ischemic stroke are speech disturbance and weakness on one-half of the body. The most common conditions that can mimic a stroke are seizure, conversion disorder, migraine headache, and hypoglycemia. Taking a patient history and performing diagnostic studies will usually exclude stroke mimics. Neuroimaging is required to differentiate ischemi...
Source: American Family Physician - April 15, 2015 Category: Primary Care Authors: Yew KS, Cheng EM Tags: Am Fam Physician Source Type: research

Abstract 219: Interdisciplinary Education and Relationship Building Improve Communication and Coordination in Stroke Care Session Title: Poster Session II
Conclusion: Through providing education to EMS providers and building relationships between EMS and hospitals, there has been a significant increase in pre-notification by EMS therefore improving timeliness of CT scans in acute stroke patients.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Thorson, S., Sather, J., Alexander, J., Cook, M. Tags: Session Title: Poster Session II Source Type: research

Lesion-aphasia discordance in acute stroke among Bengali-speaking patients: Frequency, pattern, and effect on aphasia recovery
ConclusionLesion-aphasia discordance following acute stroke is not uncommon among Bengali-speaking subjects. In the discordant group, preponderance towards non-fluent aphasia was observed. Discordance occurred more frequently after hemorrhagic stroke. Subjects with lesion-discordant aphasia presented better recovery during early post-stroke phase.
Source: Journal of Neurolinguistics - July 29, 2019 Category: Speech-Language Pathology Source Type: research