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Cognition and education benefits of increased hemoglobin and blood oxygenation in children with sickle cell disease
by Joanna P. MacEwan, Allison A. King, Andy Nguyen, Anuj Mubayi, Irene Agodoa, Kim Smith-Whitley BackgroundAmong individuals with sickle cell disease (SCD), decreased hemoglobin is associated with lower oxygen saturation (SpO2) and increased risk of stroke, both of which are associated with lower intelligence quotient (IQ) scores. Thus, increasing hemoglobin and SpO2 in individuals with SCD may increase IQ and educational attainment. MethodsA cohort simulation model was built to determine academic performance and educational attainment based on cognitive function (measured by IQ) of a pediatric SCD cohort randomly assigned...
Source: PLoS One - August 8, 2023 Category: Biomedical Science Authors: Joanna P. MacEwan Source Type: research

Where You Live Can Shape How Alzheimer ’ s Affects You
The FDA in mid-July for the first time ever approved an Alzheimer’s drug, Leqembi. The annual price-tag will run patients $26,500. The same week, the Alzheimer’s Association for the first time ever released county-level data to identify which communities are most struggling with the disease. 6.7 million Americans live with Alzheimer’s disease and 134,000 of them will die because of it each year. We’ve known these aggregate numbers for a while now, but with new data and new drugs, healthcare specialists can now better target attention and resources. [time-brightcove not-tgx=”true”] ...
Source: TIME: Health - August 7, 2023 Category: Consumer Health News Authors: Jeremy Ney Tags: Uncategorized freelance Source Type: news

Extreme Heat Is Endangering America ’ s Workers —And Its Economy
This project was supported by the Pulitzer Center 7 A.M.: COPELAND FARMS—ROCHELLE, GA Just after dawn on a recent July day in Rochelle, Ga., Silvia Moreno Ayala steps into a pair of sturdy work pants, slips on a long-sleeved shirt, and slathers her face and hands with sunscreen. She drapes a flowered scarf over her wide-brimmed hat to protect her neck and back from the punishing rays of the sun. There isn’t much she can do about the humidity, however. Morning is supposed to be the coolest part of the day, but sweat is already pooling in her rubber boots. [time-brightcove not-tgx=”true”] ...
Source: TIME: Health - August 3, 2023 Category: Consumer Health News Authors: Aryn Baker / Georgia Tags: Uncategorized climate change Climate Is Everything feature healthscienceclimate Source Type: news

Association between depression and chronic diseases among middle-aged and older Chinese adults
CONCLUSION: Depressive symptoms were significantly associated with chronic diseases (including diabetes, hypertension, heart disease, and stroke), which suggests that psychological factors, such as depressive symptoms should be taken into consideration in the prevention and control of chronic diseases.PMID:37534639
Source: Cancer Control - August 3, 2023 Category: Cancer & Oncology Authors: C S Zhu Z W Lian Y M Cui Source Type: research

Machine learning in the prediction of post-stroke cognitive impairment: a systematic review and meta-analysis
ConclusionML is a potential tool for predicting PSCI and may be used to develop simple clinical scoring scales for subsequent clinical use.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=383476.
Source: Frontiers in Neurology - August 3, 2023 Category: Neurology Source Type: research

Will unpredictable side effects dim the promise of new Alzheimer ’s drugs?
A sea change is underway in the treatment of Alzheimer’s disease, where for the first time a drug that targets the disease’s pathology and clearly slows cognitive decline has hit the U.S. market. A related therapy will likely be approved in the coming months. As many neurologists, patients, and brain scientists celebrate, they’re also nervously eyeing complications from treatment: brain swelling and bleeding, which in clinical trials affected up to about one-third of patients and ranged from asymptomatic to fatal. The side effect—amyloid-related imaging abnormalities, or ARIA—remains mysterious. “We don’...
Source: Science of Aging Knowledge Environment - August 2, 2023 Category: Geriatrics Source Type: research

Awareness of stroke among patients with chronic kidney disease on hemodialysis: a cross-sectional study
CONCLUSIONS: Patients on hemodialysis, especially women and older people, have little knowledge about stroke.PMID:37531492 | PMC:PMC10393371 | DOI:10.1590/1516-3180.2022.0644.R1.24042023
Source: Sao Paulo Medical Journal - August 2, 2023 Category: General Medicine Authors: Orlando Vieira Gomes Manoel Pereira Guimar ães B árbara Maria Batista Barbosa Christielle Lidianne Alencar Marinho Jandir Mendon ça Nicacio Matheus Pereira Barreira Mateus de Sousa Rodrigues Leonardo Fernandes E Santana Ubirac é Fernando Elihimas Jún Source Type: research

Health Care Disparities in Stroke Rehabilitation
This article conducted a literature review of original research articles published between 2008 and 2022. The article also expands on research that highlights stroke disparities in risk factors, rehabilitative stroke care, language barriers, outcomes for stroke survivors, and interventions focused on rehabilitative stroke disparities.
Source: Physical Medicine and Rehabilitation Clinics of North America - August 2, 2023 Category: Rehabilitation Authors: Audrie A. Chavez, Kent P. Simmonds, Aardhra M. Venkatachalam, Nneka L. Ifejika Source Type: research

Is Improving Educational Attainment Key to Reducing the Burden Because of Cardiovascular Diseases?
Cardiovascular diseases (CVDs) impose a substantial global public health burden, accounting for significant mortality and disability worldwide, particularly because of conditions like coronary heart disease and stroke. The economic consequences of CVDs, including healthcare expenses, decreased productivity, and diminished quality of life, further contribute to this burden. Lifestyle factors such as unhealthy diets, physical inactivity, tobacco use, and excessive alcohol consumption are closely associated with CVDs.
Source: The American Journal of Cardiology - August 1, 2023 Category: Cardiology Authors: Jari Antero Laukkanen, Setor Kwadzo Kunutsor Tags: Editorial Source Type: research

Thematic Analysis of Psychosocial Stressors and Adaptive Coping Strategies Among Informal Caregivers of Patients Surviving ICU Admission for Coma
ConclusionsIn response to substantial stressors, family caregivers of patients with SABI attempted to enact various psychological and behavioral coping strategies. They described avoidance and distraction as less helpful than other coping strategies but had difficulty engaging in alternative strategies because of their emotional distress. These findings can directly inform the development of additional resources to mitigate the long-term impact of acute psychological distress among this caregiver population.
Source: Neurocritical Care - July 31, 2023 Category: Neurology Source Type: research