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Association of serum biomarkers with early neurologic improvement after intravenous thrombolysis in ischemic stroke
ConclusionsWe found that serum levels of CCL-23, CXCL-12, IGFBP-6, IL-5, LYVE-1, PAI-1, PDGF-AA, ST-2, and TNF- α at admission were associated with post-thrombolytic ENI in stroke. The role of biomarkers warrants further investigation. Trial registrationClinical Trial Registration: https://www.clinicaltrials.gov; identifier: NCT02854592.
Source: PLoS One - October 31, 2022 Category: Biomedical Science Authors: Yu Cui Source Type: research

The effects of omega-3 fatty acids in type 2 diabetes: A systematic review and meta-analysis
The number of patients with type 2 diabetes continues to increase worldwide, the disease currently affects more than 463 million people worldwide and accounts for 10% of health care spending according to data by the World Health Organization[1]. Type 2 diabetes is a multifactorial disease that is caused by pancreatic beta-cell dysfunction and insulin resistance in peripheral tissues[2], and both morbidity and mortality are high particularly due to its associated macrovascular diseases complications (Coronary artery disease (CAD), peripheral artery disease (PAD) and stroke), as well as microvascular disease complications (d...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - June 3, 2022 Category: Biomedical Science Authors: Yanan Xiao, Qifang Zhang, Xueling Liao, Ulf Elbelt, Karsten H. Weylandt Tags: Original research article Source Type: research

Determining the role of SGLT2 inhibition with Empagliflozin in the development of diabetic retinopathy
Biosci Rep. 2022 Mar 31;42(3):BSR20212209. doi: 10.1042/BSR20212209.ABSTRACTDiabetes mellitus is a chronic metabolic disease that occurs when the pancreas is not producing enough insulin or when the insulin that it does produce is not able to be used effectively in the body. This results in hyperglycemia and if the blood sugars are not controlled, then it can lead to serious damage of various body systems, especially the nerves and the blood vessels. Uncontrolled diabetes is a major cause of kidney failure, heart attacks, stroke and amputation. One of the most devastating complications for patients is diabetic retinopathy ...
Source: Bioscience Reports - March 2, 2022 Category: Biomedical Science Authors: Jennifer Matthews Lakshini Herat Jennifer Rooney Elizabeth Rakoczy Markus Schlaich Vance B Matthews Source Type: research

Association between Coronary Artery Spasm and the risk of incident Diabetes: A Nationwide population-based Cohort Study
Conclusion: CAS is a risk factor for incident diabetes regardless of sex. However, females aged <50 years have a more apparent risk for CAS-related diabetes than old females, which is not observed in males. The median time of 2.9 years to incident diabetes warrants close follow-up.PMID:34104095 | PMC:PMC8176166 | DOI:10.7150/ijms.57987
Source: International Journal of Medical Sciences - June 9, 2021 Category: Biomedical Science Authors: Ming-Jui Hung Nen-Chung Chang Patrick Hu Tien-Hsing Chen Chun-Tai Mao Chi-Tai Yeh Ming-Yow Hung Source Type: research

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