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Condition: Stroke
Drug: Aspirin
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Total 3663 results found since Jan 2013.
Immature platelets and cardiovascular events in patients with stable coronary artery disease
Platelets. 2023 Dec;34(1):2217960. doi: 10.1080/09537104.2023.2217960.ABSTRACTMany patients with coronary artery disease (CAD) have reduced the effect of aspirin, which may partly be explained by immature platelets. We aimed to investigate whether immature platelet markers can predict cardiovascular events in a large cohort of stable CAD patients. A total of 900 stable CAD patients were included and followed for a median of 3 years. We measured markers of immature platelets (platelet count, immature platelet count, immature platelet fraction, mean platelet volume, platelet distribution width, platelet mass, and thrombopoie...
Source: Platelets - May 29, 2023 Category: Hematology Authors: Oliver Buchhave Pedersen Sanne B øjet Larsen Steen Dalby Kristensen Anne-Mette Hvas Erik Lerkevang Grove Source Type: research
A Rare Cause of Life-Threatening Upper Gastrointestinal Bleeding
Question: A 66-year-old woman presented to the hospital with large-volume hematemesis and melena. Her past medical history was significant for an episode of native valve infective endocarditis secondary to a skin infection 4 years earlier, with an associated embolic stroke of the left middle cerebral artery. Her daily medications included aspirin and atorvastatin. She denied any intake of other non-steroidal anti-inflammatory drugs. She had no history of peptic ulcer disease or liver disease. On arrival to the hospital, the patient ’s blood pressure was 90/60 mm Hg, with a heart rate of 140 beats/min.
Source: Gastroenterology - May 26, 2023 Category: Gastroenterology Authors: Howard Guo, Jesse Stach, Paul J. Belletrutti Tags: Electronic Curbside Consult Source Type: research
Acute carotid stenting plus aspirin during thrombectomy of tandem occlusions: A matched case-control study
CONCLUSIONS: Acute CAS plus Aspirin during thrombectomy for tandem occlusion stroke appears safe. Randomized trials are warranted to confirm these findings.PMID:37229632 | DOI:10.1177/15910199231175375
Source: Interventional Neuroradiology - May 25, 2023 Category: Radiology Authors: Mohamed-Isma ël Yahia Gaultier Marnat Stephanos Finitsis Igor Sibon Jean-Marc Olivot Raoul Pop Mohammad Anadani S ébastien Richard Benjamin Gory Source Type: research
Tirofiban combined with Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY): protocol for a multicentre, randomised controlled trial
DISCUSSION: The STRATEGY trial will assess whether tirofiban combined with aspirin is effective and safe in preventing recurrence and END in patients with PAI.TRIAL REGISTRATION NUMBER: NCT05310968.PMID:37220998 | DOI:10.1136/svn-2022-002284
Source: Atherosclerosis - May 23, 2023 Category: Cardiology Authors: Xiaoling Liao Shuo Feng Yicong Wang Yuesong Pan Weiqi Chen Hui Qu Xingquan Zhao Liping Liu Yongjun Wang Yilong Wang Source Type: research
Effects of long-term regular oral aspirin combined with atorvastatin to prevent ischemic stroke on human gut microbiota
CONCLUSIONS: Our findings indicated that long-term regular oral aspirin and atorvastatin modulate the human gut microbiota. Taking these drugs may affect the preventive effect of ischemic stroke by changing the abundance of specific gut microbiota.PMID:37201625 | DOI:10.1016/j.ejphar.2023.175800
Source: European Journal of Pharmacology - May 18, 2023 Category: Drugs & Pharmacology Authors: Guangtang Chen Zili Wang Wenxue Song Yidong Liao Xudong Wang Chen Chen Jiang Ming Junshuan Cui Kaya Xu Source Type: research
Prevention of Venous Thromboembolism in Medical Patients with Thrombocytopenia or with Platelet Dysfunction: The Last 10 Years
Semin Thromb Hemost DOI: 10.1055/s-0043-1769013Current guideline recommendations for primary prophylaxis of venous thromboembolism (VTE) are based on randomized clinical trials that usually exclude subjects at a potentially high risk of bleeding complications. For this reason, no specific guideline is available for thromboprophylaxis in hospitalized patients with thrombocytopenia and/or platelet dysfunction. However, except in patients with absolute contraindications to anticoagulant drugs, antithrombotic prophylaxis should always be considered, for example, in hospitalized cancer patients with thrombocytopenia, especially...
Source: Seminars in Thrombosis and Hemostasis - May 18, 2023 Category: Hematology Authors: Tufano, Antonella Brenner, Benjamin Tags: Review Article Source Type: research
Dual Antiplatelet Therapy Duration After Multivessel Optimal Intravascular Ultrasound-Guided Percutaneous Coronary Intervention
CONCLUSIONS: The adoption of short DAPT duration was still low in this trial conducted after the release of the STOPDAPT-2 trial results. The 1-year incidence of cardiovascular events was not different between the shorter and longer DAPT groups, suggesting no apparent benefit of prolonged DAPT in reducing cardiovascular events even in patients who undergo multivessel PCI.PMID:37197941 | DOI:10.1253/circj.CJ-23-0141
Source: Circulation Journal - May 17, 2023 Category: Cardiology Authors: Ko Yamamoto Hiroki Shiomi Takeshi Morimoto Akiyoshi Miyazawa Hiroki Watanabe Sunao Nakamura Satoru Suwa Takenori Domei Koh Ono Hiroki Sakamoto Masataka Shigetoshi Ryoji Taniguchi Hideki Okayama Takafumi Yokomatsu Masahiro Muto Ren Kawaguchi Koichi Kishi M Source Type: research
Capsular warning syndrome and its clinical awareness and therapeutic approach: two case reports and a systematic review of the literature
ConclusionOur cases fit with the description of patients with partial recovery and risk factors (hypertension, diabetes, and smoking) in male patients. There is a lack of evidence regarding the best treatment option; dual antiplatelet therapy and anticoagulation therapy are strong contenders for a favorable result.
Source: Frontiers in Neurology - May 16, 2023 Category: Neurology Source Type: research
Can aspirin reduce heart attack and stroke risk in patients with pneumonia?
A pneumonia trial – the largest ever – will investigate whether aspirin can reduce the risk of a heart attack or stroke in patients who are admitted to hospital with pneumonia.
Source: University of Bristol news - May 9, 2023 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Translational Health Sciences; Press Release Source Type: news
Tirofiban in the treatment of cancer-associated ischemic stroke
CONCLUSIONS: Early administration of tirofiban in the treatment of mild to moderate ischemic stroke is safe, which can reduce 24-hour and 7-day NIHSS scores and has potential value.PMID:37140310 | DOI:10.26355/eurrev_202304_32142
Source: Pharmacological Reviews - May 4, 2023 Category: Drugs & Pharmacology Authors: Z-M Zhang Z-H Lin G-L Zhu Source Type: research
