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Drug: Clopidogrel
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Total 1913 results found since Jan 2013.
Recombinant tissue-type plasminogen activator (rt-PA) effectively restores neurological function and improves prognosis in acute ischemic stroke
CONCLUSION: Compared with conventional pharmacological regimens, additional rt-PA intravenous thrombolytic therapy improves the clinical outcome of patients with acute ischemic stroke, promotes neurological recovery, and enhances patient prognosis without increasing the risk of patient-related adverse events.PMID:37303683 | PMC:PMC10251022
Source: American Journal of Translational Research - June 12, 2023 Category: Research Authors: Shouyun Zhang Dezhen Wang Lin Li Source Type: research
Human Serum Albumin-enriched Clopidogrel Bisulfate Nanoparticle Alleviates Cerebral Ischemia –Reperfusion Injury in Rats
ConclusionsCLP-ANPs represent a promising and translatable platform system for the management of cerebral I/R injury during ischemic stroke.
Source: Pharmaceutical Research - June 8, 2023 Category: Drugs & Pharmacology Source Type: research
Association between post-stroke smoking and stroke recurrence in first-ever ischemic stroke survivors: based on a 10-year prospective cohort
ConclusionsSmoking could elevate the risk of IS recurrence, and IS survivor should be advised to quit or smoke less. Add-on effect of clopidogrel may not exist in smoking strokers taking clopidogrel.
Source: Neurological Sciences - June 8, 2023 Category: Neurology Source Type: research
An elderly case with late carotid stent thrombosis: possible role of antiphospholipid antibodies
The case study speculates that the antiphospholipid antibodies acquired during the follow-up period of carotid artery stenting may cause late stent thrombosis that is resistant to direct oral anticoagulants. A 73-year-old man was hospitalized with complaints of weakness in the right lower extremity. The patient had undergone carotid artery stenting for symptomatic stenosis of the left internal carotid artery 6 years prior and had received antiplatelet therapy with clopidogrel 75 mg/day. As the patient had developed atrial fibrillation without stent stenosis at the age of 70 years, anticoagulation therapy with rivaroxaban...
Source: Journal of Stroke and Cerebrovascular Diseases - May 26, 2023 Category: Neurology Authors: Shinji Kitsuki, Kenji Fukuda, Tomonaga Matsushita, Yoshihisa Fukushima, Tetsuro Ago, Takanari Kitazono Tags: Case Report Source Type: research
Capsular warning syndrome and its clinical awareness and therapeutic approach: two case reports and a systematic review of the literature
ConclusionOur cases fit with the description of patients with partial recovery and risk factors (hypertension, diabetes, and smoking) in male patients. There is a lack of evidence regarding the best treatment option; dual antiplatelet therapy and anticoagulation therapy are strong contenders for a favorable result.
Source: Frontiers in Neurology - May 16, 2023 Category: Neurology Source Type: research
