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Total 78 results found since Jan 2013.

COVID-19 independently predicts poor outcomes in Acute Ischemic Stroke- Insights from a multicenter study from Pakistan and United Arab Emirates
Ischemic stroke associated with coronavirus 2019 (COVID-19) has been well recognized by now. Few studies have compared COVID related versus unrelated strokes. We intend to report on a large group of Asian patients from two countries and compare COVID with non-COVID strokes admitted during the same time period.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2022 Category: Neurology Authors: Maria Khan, Sajid Hameed, Bashir A Soomro, Samar Iltaf, Abdul Malik, Saba Farooq, Suhail Al Rukn, Mohammad Wasay Source Type: research

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration
Conclusion The developed and validated method to quantify neurounina-1 in beagle dog plasma using LC-MS/MS presented sensitivity and selectivity, thus allowing the rapid and precise determination of the pharmacokinetics of this neuroprotective compound working in the low nanomolar range. Ethics Statement This study was carried out in accordance with the recommendations of the general ethical guidelines established by the Brazilian Society for Laboratory Animal Science (SBCAL). The protocol was approved by the Committee for Ethics in Animal Use – State University of Campinas (CEUA/UNICAMP, protocol n° 3340-...
Source: Frontiers in Pharmacology - April 24, 2019 Category: Drugs & Pharmacology Source Type: research

Clinical Features and Management of Ischemic Stroke in Pakistan (P02.031)
CONCLUSIONS: Risk factors for stroke in Pakistan are similar to patients in North America. However the majority of patients are either unaware or have poor management of stroke risk factors. Efforts at risk factor management are important to reduce the burden of stroke in this population.Disclosure: Dr. Khan has nothing to disclose. Dr. Shuaib has nothing to disclose. Dr. Khatri has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Farooq has nothing to disclose. Dr. Mehboob has nothing to disclose. Dr. Khattak has nothing to disclose. Dr. Nazir has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Khan, H., Shuaib, U., Khatri, I., Malik, S., Farooq, U., Mehboob, N., Khattak, J., Nazir, R. Tags: P02 Cerebrovascular Disease II Source Type: research

Urdu translation and cross-cultural validation of the Fugl-Meyer assessment in people with stroke
CONCLUSION: The Urdu FMA is reliable and valid for the assessment of sensorimotor function in people with chronic stroke and can therefore be recommended for use in clinical and research applications.IMPLICATIONS FOR REHABILITATIONThe Urdu FMA is now available for use in Pakistan.The Urdu FMA is reliable and valid for the assessment of sensorimotor function in people with chronic stroke.The use of Urdu FMA is recommended to clinicians to estimate stroke severity and motor recovery.PMID:34807783 | DOI:10.1080/09638288.2021.2003449
Source: Disability and Rehabilitation - November 22, 2021 Category: Rehabilitation Authors: Mehwish Ikram Syed Shakil Ur Rehman Katharina S Sunnerhagen Margit Alt Murphy Source Type: research

The frequency and pattern of deranged lipid profile in patients with ischemic stroke: a retrospective study
Conclusions: Dyslipidemia is an important risk factor for ischemic stroke, and elevated LDL-C is usually the lipid fraction implicated in the pathologic mechanism of stroke.PMID:35775784 | DOI:10.23750/abm.v93i3.11576
Source: Acta Bio-Medica : Atenei Parmensis - July 1, 2022 Category: General Medicine Authors: Naresh Kumar Seetlani Geeta Kumari Farah Yasmin Choudhary Ahmed Hasan Maheen Hussaini Sana Awan Khalid Imran Mubeen Rakshinda Jabeen Sadia Ansari Sarush Siddiqui Momin Aziz Umer Farooque Source Type: research

Stroke Care in Pakistan
Increasing incidence of stroke and lack of infrastructure in both urban and rural areas needs immediate attention in Pakistan. There is a high proportion of young stroke with poor stroke outcomes. Acute stroke care is scarce in Pakistan due to the small number of neurologists (1 neurologist per 1 million population), few stroke units, and limited availability of alteplase (recombinant tissue plasminogen activator) in the country.Cerebrovasc Dis Extra 2021;11:118 –121
Source: Cerebrovascular Diseases Extra - October 25, 2021 Category: Neurology Source Type: research

Clinical, lifestyle, socioeconomic determinants and rate of asymptomatic intracranial atherosclerosis in stroke free Pakistanis
Conclusion: ICAD was found on MRI in one in three asymptomatic Pakistanis and was associated with modifiable risks. Initiatives targeting primary prevention may be able to decrease the burden of disease caused by stroke due to ICAD.Study Registration NumberNCT02072876 2/25/2014
Source: BMC Neurology - August 15, 2014 Category: Neurology Authors: Ayeesha KamalFarzin MajeedOmrana PashaHasan RehmanMuhammad IslamIqbal AzamMuhammad IlyasMunawar HussainKamran MasoodBilal AhmedSumaira NazirZafar SajjadScott Kasner Source Type: research

Translation and validation of the stroke impact scale 3.0 into urdu for Pakistan
CONCLUSIONS: The USIS 3.0 has satisfactory psychometric properties and can be used in clinical and research settings for stroke survivors.PMID:34420984 | DOI:10.3233/NRE-210064
Source: NeuroRehabilitation - August 23, 2021 Category: Rehabilitation Authors: Umair Ahmed Hossein Karimi Syed Amir Gilani Ashfaq Ahmad Source Type: research