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Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM < sub > 2.5 < /sub > , BC, NO < sub > 2 < /sub > , and O < sub > 3 < /sub > : An Analysis of European Cohorts in the ELAPSE Project
CONCLUSIONS: Long-term exposure to PM2.5, NO2, and BC was positively associated with natural-cause and cause-specific mortality in the pooled cohort and the administrative cohorts. Associations were found well below current limit values and guidelines for PM2.5 and NO2. Associations tended to be supralinear, with steeper slopes at low exposures with no indication of a threshold. Two-pollutant models documented the importance of characterizing the ambient mixture with both NO2 and PM2.5. We mostly found negative associations with O3. In two-pollutant models with NO2, the negative associations with O3 were attenuated to esse...
Source: Cancer Control - September 15, 2022 Category: Cancer & Oncology Authors: Brunekreef Bert Strak Maciej Chen Jie J Andersen Zorana Atkinson Richard Bauwelinck Mariska Bellander Tom Boutron Marie-Christine Brandt J ørgen Carey Iain Cesaroni Giulia Forastiere Francesco Fecht Daniela Gulliver John Hertel Ole Hoffmann Barbara de Ho Source Type: research

Lifestyle behaviours predicting major cardiovascular diseases mortality in a practically extinct cohort of middle-aged men followed-up for 61 years
Acta Cardiol. 2022 Jul 29:1-8. doi: 10.1080/00015385.2022.2101876. Online ahead of print.ABSTRACTTo study lifetime relationships of three major lifestyle behaviours with cardiovascular mortality in a cohort of middle-aged men that reached practical extinction. In the Italian Areas of the Seven Countries Study of Cardiovascular Diseases (SCS), 1712 men were enrolled and examined in 1960, and behavioural habits were measured: smoking habits, physical activity and diet each divided into three classes. Follow-up for mortality was extended for 61 years. Three groups of major cardiovascular diseases (CVD) were used for analysis,...
Source: Acta Cardiologica - July 29, 2022 Category: Cardiology Authors: Alessandro Menotti Paolo Emilio Puddu Giovina Catasta Source Type: research

Trends of overweight, obesity and anthropometric measurements among the adult population in Italy: The CUORE Project health examination surveys 1998, 2008, and 2018
ConclusionsAlthough the overall trend of excess weight over the past two decades appeared to be substantially stable in the Italian adult population, the continuous strengthening of undertaken initiatives should continue since there remains a high proportion of overweight or obesity and a gap between educational levels.
Source: PLoS One - March 1, 2022 Category: Biomedical Science Authors: Chiara Donfrancesco Source Type: research

Effects of a gluten-reduced or gluten-free diet for the primary prevention of cardiovascular disease
CONCLUSIONS: Very low-certainty evidence suggested that it is unclear whether gluten intake is associated with all-cause mortality. Our findings also indicate that low-certainty evidence may show little or no association between gluten intake and cardiovascular mortality and non-fatal myocardial infarction. Low-certainty evidence suggested that a lower compared with a higher gluten intake may be associated with a slightly increased risk to develop type 2 diabetes - a major cardiovascular risk factor. For other cardiovascular risk factors it is unclear whether there is a difference between a gluten-free and normal diet. Giv...
Source: Cochrane Database of Systematic Reviews - February 24, 2022 Category: General Medicine Authors: Christine Schmucker Angelika Eisele-Metzger Joerg J Meerpohl Cornelius Lehane Daniela Kuellenberg de Gaudry Szimonetta Lohner Lukas Schwingshackl Source Type: research

Association of physical activity trajectories with major cardiovascular diseases in elderly people
Conclusion Increasingly active trajectories of physical activity were associated with lower rates of cardiovascular diseases and overall mortality. Promoting at least 20 min/day of physical activity early in late life seems to provide the greatest cardiovascular benefits.
Source: Heart - February 16, 2022 Category: Cardiology Authors: Barbiellini Amidei, C., Trevisan, C., Dotto, M., Ferroni, E., Noale, M., Maggi, S., Corti, M. C., Baggio, G., Fedeli, U., Sergi, G. Tags: Editor's choice Cardiac risk factors and prevention Source Type: research

Impact of Sex on Office White Coat Effect Tail: A Review.
Abstract Office white-coat effect tail (OWCET) is defined as a decrease of ≥10 mmHg in systolic blood pressure (SBP) between successive measurements after its waxing during an office visit. The influence of sex on the incidence of long-term major fatal and non-fatal cardiovascular events was studied in two Italian populational cohorts [from the Gubbio Study and the Italian Rural Areas of the Seven Countries Study (IRA)]. OWCET increased risk of cardiovascular disease (CVD) [HR: 1.591 (95%CI: 1.204-2.103)], coronary heart disease (CHD) [HR: 1.614 (95%CI: 1.037-2.512)] and stroke (STR) [HR: 1.696 (95%CI: 1.123-2.5...
Source: Current Pharmaceutical Design - January 12, 2021 Category: Drugs & Pharmacology Authors: Humbert X, Fedrizzi S, Hofferer A, Bansard M, Huet AL, Bedier C, Rabiaza A, Le Bas J, Bas FL, Alexandre J, Puddu PE Tags: Curr Pharm Des Source Type: research

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