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Iran Quality of Care in Medicine Program (IQCAMP): Design and Outcomes
CONCLUSION: The IQCAMP study was the first healthcare utilization, cost, and quality survey in Iran with a longitudinal data collection to represent the pattern, quantity, and quality of medical care provided for high-burden conditions.PMID:37543935 | DOI:10.34172/aim.2023.21
Source: Archives of Iranian Medicine - August 6, 2023 Category: Middle East Health Authors: Saeid Shahraz Sarvenaz Shahin Yosef Farzi Mitra Modirian Nazila Shahbal Mehrdad Azmin Farnam Mohebi Mohammadreza Naderian Masoume Amin-Esmaeili Naser Ahmadi Shahedeh Seyfi Hossein Zokaei Roya Samadi Bahram Mohajer Roya Sherafat-Kazemzadeh Abbas Balouchi B Source Type: research

Measuring the burden of comorbidity for ischaemic heart disease and four common non-communicable diseases in Iran, 1990-2017: a modelling study based on global burden of diseases data
Conclusion Of the four comorbidities studied, the highest burden was due to the coexistence of MDD with IHD. Our results highlight the importance of addressing the burden of comorbidities when studying the burden of IHD or any other non-communicable disease.
Source: BMJ Open - November 17, 2022 Category: General Medicine Authors: Mansourian, M., Ghasemi, K., Haghdoost, A., Kopec, J. A., Sarrafzadegan, N., Islam, S. M. S. Tags: Open access, Epidemiology Source Type: research

Validation of the Persian Version of the Engagement in Meaningful Activities Survey (EMAS) in an Iranian Stroke Population: Predictors of Participation in Meaningful Activities
CONCLUSIONS AND RELEVANCE: The results indicate that the EMAS-P has acceptable reliability and validity among Iranian people with chronic stroke. Moreover, the EMAS-P showed good discriminant validity for age, depression, and disability level among them. What This Article Adds: The EMAS-P is a reliable and valid scale for assessing the engagement of Iranian chronic stroke survivors in meaningful activities and thus should be helpful in both clinical research and practice.PMID:35771732 | DOI:10.5014/ajot.2022.046623
Source: The American Journal of Occupational Therapy - June 30, 2022 Category: Occupational Health Authors: Moslem Cheraghifard Malahat Akbarfahimi Akram Azad Aaron M Eakman Ghorban Taghizadeh Source Type: research

Associations Between Two Single-Nucleotide Polymorphisms in NINJ2 Gene and Risk of Psychiatric Disorders
AbstractNINJ2 encodes a transmembrane protein that contributes in neurodevelopment and regeneration of neurons. Single-nucleotide polymorphisms (SNPs) within this gene have been associated with Alzheimer ’s disease, ischemic stroke, and multiple sclerosis. The rs11833579 and rs3809263 SNPs have been associated with risk of ischemic stroke in Iranian population. While theNINJ2 rs12425791 has been with risk of ischemic stroke in East Asian population, the rs11833579 has not been associated with this condition either in East Asian population or Chinese Han population. In the current project, we genotyped rs11833579 and rs38...
Source: Journal of Molecular Neuroscience - December 22, 2019 Category: Neuroscience Source Type: research

Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer ’s Disease Through Activation of BDNF-TrkB Signaling Pathway
Conclusion The data in this manuscript demonstrates that apelin-13 upregulates BDNF against STZ-induced congnitive impairment by suppressing glial cell activity and inflammatory factors release. This suggests apelin signaling may be a new target in the treatment of AD. Ethics Statement All experimental protocols were carried out according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals approved by the Central South University at XiangYa Animal Care and Use Committee. Author Contributions XqQ and LH conceived the study and contributed to its experimental design. HqL carried out the...
Source: Frontiers in Pharmacology - April 15, 2019 Category: Drugs & Pharmacology Source Type: research

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

Association Between Trace Element Status and Depression in HTLV-1-Infected Patients: a Retrospective Cohort Study.
Abstract Depression and Anxiety are two important public health problems that are known to be associated with viral infections. The association between the intake of nutrients such as zinc and copper with symptoms of depression has been studied previously. The aim of the current study was to investigate the association between depression with human T cell lymphotropic virus type 1 (HTLV-1) infection and serum content of zinc and copper in a large Iranian population cohort. The study population consisted of 279 HTLV-1-positive patients who were identified after recruitment as part of a large cohort study: the Mashh...
Source: Biological Trace Element Research - February 4, 2019 Category: Biology Authors: Darroudi S, Abolbashari S, Ahangari N, Tayefi M, Khashyarmanesh Z, Zamani P, Haghighi HM, Mohammadpour AH, Tavalaei S, Esmaily H, Ferns GA, Meshkat Z, Tayefi B, Ghayour-Mobarhan M Tags: Biol Trace Elem Res Source Type: research

Validation of the 5-Item Medication Adherence Report Scale in Older Stroke Patients in Iran
Conclusions: The MARS-5 is a feasible and valid self-assessed medication adherence for older patients with stroke. In addition, several determinants were found to be related to medication adherence for older patients with stroke. Healthcare providers may want to take heed of these determinants to improve medication adherence for this population.
Source: Journal of Cardiovascular Nursing - October 11, 2018 Category: Nursing Tags: ARTICLES: Heart Failure Source Type: research

Wants Talk Psychotherapy but Cannot Talk: EMDR for Post-stroke Depression with Expressive Aphasia
CONCLUSION This is the first reported case demonstrating that EMDR can be effective for depression, even in those with severe expressive aphasia. In our case, there was no reluctance to disclose information, simply a neurological inability to do so. Through preparation, patience, perseverance, and plasticity (clinician flexibility, though perhaps also neuroplasticity), the patient’s PSD gradually improved, and she was able to reinvent her life within her limitations. ACKNOWLEDGMENTS The authors gratefully acknowledge Eugene Schwartz, E.C. Hurley, and Mark Hubner for providing consultation during patient care. REFERENCES ...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Case Report Current Issue Neurologic Systems and Symptoms Neurology Psychotherapy Stroke aphasia depression EMDR Source Type: research

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