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Total 106 results found since Jan 2013.
Genetic study of the NOTCH3 gene in CADASIL patients
ConclusionWe found four novel mutations (P109T, P203H, IVS7 + 15A>G and IVS7 + 16A>G) and 2 reported NOTCH3 mutations. Exon 4 and Intron 7 are hotspots in the patients we examined with the NOTCH3 mutations. These findings broaden the mutational spectrum of CADASIL.
Source: Egyptian Journal of Medical Human Genetics - July 5, 2018 Category: Genetics & Stem Cells Source Type: research
Subclinical myocardial dysfunction by tissue Doppler echocardiography in primary antiphospholipid syndrome: Preliminary results
ConclusionThe present study demonstrated subclinical myocardial dysfunction using TDI in asymptomatic PAPS patients. TDI is non-invasive and cost effective. Prospective studies including a large number of participants in order to confirm these preliminary data are needed.
Source: The Egyptian Rheumatologist - July 5, 2018 Category: Rheumatology Source Type: research
Role of speckle tracking echocardiography in detecting early left atrial dysfunction in hypertensive patients
ConclusionSpeckle tracking echocardiography is a useful novel technique in detecting LA dysfunction in hypertension even before LA enlargement occurs.
Source: The Egyptian Heart Journal - July 5, 2018 Category: Cardiology Source Type: research
Clinical safety profile of ticagrelor compared to clopidogrel in 1208 patients: Real world evidence
ConclusionIn the real world settings, patients undergoing PCI treated with ticagrelor showed similar safety profile compared to clopidogrel but with increase in minor bleeding rate. The observed results were in alignment with PLATO clinical trial.
Source: The Egyptian Heart Journal - July 5, 2018 Category: Cardiology Source Type: research
Impact of elevated glycosylated hemoglobin on hospital outcome and 1 year survival of primary isolated coronary artery bypass grafting patients
ConclusionsThis study showed that HbA1c is a good predictor of in-hospital morbidity. It worth devoting time and effort to decrease HbA1c level below 7% to decrease possible postoperative complications.
Source: The Egyptian Heart Journal - July 5, 2018 Category: Cardiology Source Type: research
New funding to UC Riverside to significantly boost cancer, ALS research
(University of California - Riverside) Maurizio Pellecchia at the University of California, Riverside has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis (ALS), and other neurodegenerative diseases. The first grant from the US-Egypt Science and Technology Joint Fund of the National Academy of Sciences, Engineering, and Medicine totals $190,000 for two years. The second is a nearly $2.3 million, five-year grant from the National Institute of Neurological Disorders and Stroke.
Source: EurekAlert! - Cancer - June 21, 2018 Category: Cancer & Oncology Source Type: news
Role of speckle tracking echocardiography in detecting early left atrial dysfunction in hypertensive patients
Conclusion Speckle tracking echocardiography is a useful novel technique in detecting LA dysfunction in hypertension even before LA enlargement occurs.
Source: The Egyptian Heart Journal - June 19, 2018 Category: Cardiology Source Type: research
Clinical safety profile of ticagrelor compared to clopidogrel in 1208 patients: Real world evidence
Conclusion In the real world settings, patients undergoing PCI treated with ticagrelor showed similar safety profile compared to clopidogrel but with increase in minor bleeding rate. The observed results were in alignment with PLATO clinical trial.
Source: The Egyptian Heart Journal - June 14, 2018 Category: Cardiology Source Type: research
World No Tobacco Day 2018: Tobacco breaks hearts
Cairo, Egypt, 31 May – Every year, on 31 May, the World Health Organization (WHO) and partners mark World No Tobacco Day, highlighting the health and other risks associated with tobacco use, and advocating for effective policies to reduce tobacco consumption. This year, World No Tobacco Day focuses on tobacco and heart disease. The campaign’s slogan is “Tobacco breaks hearts. Choose health, not tobacco”.
Tobacco use is one of the leading causes of premature death and disability worldwide. It is also a key risk factor for the development of coronary heart disease, stroke and peripheral vascular disease. “In most ...
Source: WHO EMRO News - May 26, 2018 Category: Middle East Health Source Type: news
Genetic study of the NOTCH3 gene in CADASIL patients
Conclusion We found four novel mutations (P109T, P203H, IVS7 + 15A>G and IVS7 + 16A>G) and 2 reported NOTCH3 mutations. Exon 4 and Intron 7 are hotspots in the patients we examined with the NOTCH3 mutations. These findings broaden the mutational spectrum of CADASIL.
Source: Egyptian Journal of Medical Human Genetics - May 24, 2018 Category: Genetics & Stem Cells Source Type: research
Thrombomodulin, alarmin signaling, and copeptin: cross-talk between obesity and acute ischemic stroke initiation and severity in Egyptians
In conclusion, these results highlighted detr imental role of alarmin signaling with increased adaptive response to block this pathway through TM in addition to increased copeptin level as an acute damage marker and their tight relation to WC not to BMI in AIS which clarify the implication of central adiposity.
Source: Neurological Sciences - April 10, 2018 Category: Neurology Source Type: research
Primary PCI versus Pharmaco-Invasive Strategy in Patients with ST-Elevation Myocardial Infarction; a Randomized Clinical Study
Conclusion: Immediate fibrinolysis followed by coronary angiography 3-24 hr later resulted in similar short term outcome and earlier effective reperfusion in patients with STEMI compared to PPCI.Keywords:Fibrinolysis,PCI,Reperfusion,STEMIView:PDF (323.13 KB)Click here to download the PDF file.‹ Probability of Dying and Survival Analysis of Diabetic and/Hypertensive Patients Who Undergone Hemodialysis with Heart Disease Complication: A Comparison between a Hemodialysis Center Jakarta, Indonesia and Penang, MalaysiaAssessment of Risk Factors for the Cardiovascular Diseases in People Visiting a Tertiary Care Hospital for Ro...
Source: Journal of Cardiovascular Disease Research - March 8, 2018 Category: Cardiology Authors: yunus Source Type: research
Stroke burden in Egypt: data from five epidemiological studies
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Source: International Journal of Neuroscience - January 5, 2018 Category: Neuroscience Authors: Foad Abd-Allah Eman Khedr Mohammed I Oraby Ahmed Safwat Bedair Shady Samy Georgy Ramez Reda Moustafa Source Type: research
Short term outcome of patients with hyperglycemia and acute stroke
Conclusions Hyperglycemia is associated with poor outcomes after acute stroke. History of HTN, admission glucose level ≥ 223 mg/dL and NIHSS ≥ 10 were predictors of worse stroke outcome.
Source: The Egyptian Journal of Critical Care Medicine - December 21, 2017 Category: Intensive Care Source Type: research
Value of complex evoked auditory brainstem response in patients with post-stroke aphasia (prospective study)
Conclusion Aphasic patients exhibited abnormal neural synchrony affecting the source elements (waves D, E, F and O) however there was no effect on the filter elements (transients).
Source: Egyptian Journal of Ear, Nose, Throat and Allied Sciences - December 13, 2017 Category: ENT & OMF Source Type: research
