Assessment of nutritional deficiency manifestations in patients with rheumatic diseases
Publication date: Available online 13 July 2020Source: The Egyptian RheumatologistAuthor(s): Emad Elshebini, Hozaifa Elsawah, Taghreed Fathy, Sherry Abdelrahman, Omar Youssif, Soaad Ashraf, Nibal Mourad, Mohamed Elnaggar, Ahmed Elshebiny, Shymaa Daif, Enas Zahran (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 15, 2020 Category: Rheumatology Source Type: research

Impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection and disease-2019 (COVID-19) on the quality of life of rheumatoid arthritis patients in Benin
Publication date: Available online 4 July 2020Source: The Egyptian RheumatologistAuthor(s): Zavier Zomalheto, Calixte Assogba, Hilaire Dossou-yovo (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 8, 2020 Category: Rheumatology Source Type: research

Impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection and disease -2019 (COVID-19) on the quality of life of rheumatoid arthritis patients in Benin
Publication date: Available online 4 July 2020Source: The Egyptian RheumatologistAuthor(s): Zavier Zomalheto, Calixte Assogba, Hilaire Dossou-yovo (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 6, 2020 Category: Rheumatology Source Type: research

Value of hematological parameters as biomarkers of disease manifestations and severity in systemic sclerosis
Publication date: Available online 4 July 2020Source: The Egyptian RheumatologistAuthor(s): Basma R. Sakr, Randa E. Rabea, Samah MAbd ElHamid (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 4, 2020 Category: Rheumatology Source Type: research

Potential role of high sensitivity cardiac troponin T in subclinical coronary atherosclerosis in systemic lupus erythematosus patients
Publication date: Available online 27 June 2020Source: The Egyptian RheumatologistAuthor(s): Sally S. Abdelaziz, Nermin H. El-Gharbawy, Sherihan S. Madkour, Irene R. Amin, Mervat A. Reda (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 27, 2020 Category: Rheumatology Source Type: research

Vitamin D deficiency in Egyptian and Yemeni primary knee osteoarthritis patients: Relation to physical function and radiographic severity
Publication date: Available online 27 June 2020Source: The Egyptian RheumatologistAuthor(s): Basma R. Sakr, Nabil M. Al-Ashmory, Samia Z. Hassan, Ahmed A. Al-Akwa, Olfat G. Shaker (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 27, 2020 Category: Rheumatology Source Type: research

Skin prick test with self saliva as a diagnostic test for Behçet’s disease
Publication date: Available online 25 June 2020Source: The Egyptian RheumatologistAuthor(s): Manar Farouk Mohamed, Osama Mohamed Abdel Latif, Marwa Magdi Mahmoud, Fawzia Hassan Ahmed Abo-Ali (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 26, 2020 Category: Rheumatology Source Type: research

Impact of cyclophosphamide on gonadotropins in menopausal systemic lupus erythematosus patients: Relation to disease activity and damage
Publication date: Available online 24 June 2020Source: The Egyptian RheumatologistAuthor(s): Samah A. Elbakry, Rasha M. Hamouda, Marina W. Naguib, Safaa A. Hussein (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 24, 2020 Category: Rheumatology Source Type: research

Left ventricular function and left atrial volumes in rheumatoid arthritis patients: Subclinical cardiac involvement and relation to seropositivity
Publication date: Available online 23 June 2020Source: The Egyptian RheumatologistAuthor(s): Sameh Wadeea Bakhoum, Zeinab Ateya Ashour, Mahmood Sheikh Mohammed, Mary WadieFawzy (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 23, 2020 Category: Rheumatology Source Type: research

Upregulation of microRNA-93-5p/microRNA-4668-5p, and promoter methylation of matrix metalloproteinase-3 and interleukin-16 genes in Turkish patients with rheumatoid arthritis
Publication date: Available online 21 June 2020Source: The Egyptian RheumatologistAuthor(s): Zulfinaz Betul Celik, Sengul Tural, Ahmet Kivanc Cengiz, Nurten Kara, Gamze Alayli (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 22, 2020 Category: Rheumatology Source Type: research

Antineutrophil cytoplasmic autoantibody (ANCA) positive immunoglobulin A (IgA) nephropathy: Case reports and review of literature
Publication date: Available online 11 June 2020Source: The Egyptian RheumatologistAuthor(s): Natalia Chebotareva, Elena Kamyshova, Nikolay Bulanov, Lidia Lysenko, Sergey Moiseev (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 13, 2020 Category: Rheumatology Source Type: research

Carotid intima-media thickness, lipid profile, serum amyloid A and vitamin D status in children with familial Mediterranean fever
Publication date: Available online 10 June 2020Source: The Egyptian RheumatologistAuthor(s): Ramy Mohamed, Hala T. El-Bassyouni, Sherif Hasan Elwan, Eman Youness, Doaa R. Soliman, Ghada M. Shehata, Moushira Erfan Zaki (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 11, 2020 Category: Rheumatology Source Type: research

Association of serum osteoprotegerin and osteoprotegerin gene polymorphism with subclinical carotid artery atherosclerosis and disease activity in rheumatoid arthritis patients
Publication date: Available online 4 June 2020Source: The Egyptian RheumatologistAuthor(s): Eman A.M. Alkady, Zahraa I. Selim, Sohair K. Sayed, Hosam A. Yousef, Sara Farrag, Eman H. El-Hakeim (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 5, 2020 Category: Rheumatology Source Type: research

MicroRNA-126 and 146a as potential biomarkers in systemic lupus erythematosus patients with secondary antiphospholipid syndrome
Publication date: Available online 29 May 2020Source: The Egyptian RheumatologistAuthor(s): Diana Nagy, Noha H. Shaheen, Heba M. Selim, Mai M. Sherif, Salma M. Saed, Hala R. Youssef, Omneya Osman, Taghrid Gaafar (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - May 30, 2020 Category: Rheumatology Source Type: research

Association of tumor necrosis factor-α (TNF-α) −308A/G (rs1800629) gene polymorphism with carotid artery atherosclerosis in rheumatoid arthritis patients
Publication date: Available online 28 May 2020Source: The Egyptian RheumatologistAuthor(s): Rasha M. Fawzy, Gamal A. Hammad, Samy E. Egila, Amira N. Elkasas, Nehad A. Fouad (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - May 30, 2020 Category: Rheumatology Source Type: research

Fundus fluorescein angiography and optical coherence tomography findings in ocular and non-ocular Behҫet’s disease
Publication date: Available online 27 May 2020Source: The Egyptian RheumatologistAuthor(s): Sara Mamdouh, Maha Youssef, Dina El-Fayoumi, Magda Salah (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - May 29, 2020 Category: Rheumatology Source Type: research

Efficacy and safety of adalimumab as the first- and second-line biologic therapy for children with juvenile idiopathic arthritis under four years of age
Publication date: Available online 21 April 2020Source: The Egyptian RheumatologistAuthor(s): Ekaterina Alexeeva, Tatyana Dvoryakovskaya, Rina Denisova, Tatyana Sleptsova, Kseniya Isaeva, Alexandra Chomahidze, Anna Fetisova, Anna Mamutova, Alina Alshevskaya, Andrey Moskalev (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 23, 2020 Category: Rheumatology Source Type: research

The association between adipokines and stigmata of atherosclerosis in patients with systemic lupus erythematosus
Publication date: Available online 13 March 2020Source: The Egyptian RheumatologistAuthor(s): Zahra Rezaieyazdi, Zahra Mirfeizi, Mohammad Reza Hatef, Golnaz Gholami, Sima Sedighy, Habibollah Esmaily, Mahmoud Reza Azarpazhooh, Asieh Karimani, Masoumeh Salari (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - March 14, 2020 Category: Rheumatology Source Type: research

Cutaneous immunohistochemical expression of interleukin-23 receptor (IL-23R) in psoriasis and psoriatic arthritis patients: Relation to musculoskeletal ultrasound findings
Publication date: Available online 29 February 2020Source: The Egyptian RheumatologistAuthor(s): Sally El-Leithy, Nahed Sherif, Nadia H. El-Arousy, Rana El-Hilaly, Marwa M. Shakweer (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - March 1, 2020 Category: Rheumatology Source Type: research

Serum and synovial fluid interleukin-17 concentrations in rheumatoid arthritis patients: Relation to disease activity, radiographic severity and power Doppler ultrasound
Publication date: Available online 28 February 2020Source: The Egyptian RheumatologistAuthor(s): Medhat A. Farag, Fouad E. El Debaky, Shaymaa M. Abd El-Rahman, Samah M. Abd el-khalek, Rasha M. Fawzy (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - February 29, 2020 Category: Rheumatology Source Type: research

Effect of an increased dose of colchicine on microalbuminuria in children with Familial Mediterranean Fever
Publication date: Available online 27 February 2020Source: The Egyptian RheumatologistAuthor(s): Huda Marzouk, Noha Mostafa, Iman Khalifa, Nora Badawi (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - February 27, 2020 Category: Rheumatology Source Type: research

Lupus erythematosus tumidus (LET) with autoimmune thyroid dysfunction (AITD) as the first presentation of systemic lupus erythematosus: A case report and review of the literature
ConclusionLET is a rare cutaneous lupus-specific lesion that may be associated with SLE. AITD, hypothyroidism in particular, could be an initial presentation of SLE. Increased awareness and early diagnosis of such clinical presentations may improve patient outcomes. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - February 19, 2020 Category: Rheumatology Source Type: research

Health related quality of life (HRQoL) in ankylosing spondylitis patients: Relation to clinical features, disease activity and radiographic damage
Publication date: Available online 17 February 2020Source: The Egyptian RheumatologistAuthor(s): Rehab A. Sallam, Amany S. ElbahnasawyAbstractAim of the workTo assess health-related quality of life (HRQoL) and associated variables in Egyptian ankylosing spondylitis (AS) patients.Patients and methods50 male patients with AS and 50 age-matched controls were enrolled. Clinical and laboratory data were examined including history for peripheral arthritis. Visual analog scale (VAS), Bath AS disease activity index (BASDAI), AS disease activity score (ASDAS)-C-reactive protein (CRP) and ASDAS-erythrocyte sedimentation rate (ESR), ...
Source: The Egyptian Rheumatologist - February 18, 2020 Category: Rheumatology Source Type: research

Serum, synovial and mRNA expression of interleukin-33 in juvenile idiopathic arthritis patients: Potential role as a marker of disease activity and relation to musculoskeletal ultrasound
Publication date: Available online 11 February 2020Source: The Egyptian RheumatologistAuthor(s): Enas Noor-eldeen, Waleed A. Hassan, Eman G. Behiry, Abd El-hameed Abd El-monemAbstractAim of the workTo measure interleukin-33 (IL-33) serum and synovial fluid (SF) levels as well as its relative expression in peripheral blood mononuclear cells (PBMC) of juvenile idiopathic arthritis (JIA) patients and to study their relation to clinical, laboratory and musculoskeletal ultrasound characteristics, disease activity and functional status.Patients and methodsThe study included 60 JIA patients and 60 healthy controls and SF levels w...
Source: The Egyptian Rheumatologist - February 12, 2020 Category: Rheumatology Source Type: research

Organ involvement in immunoglobulin a vasculitis (Henoch-Shönlein purpura) children: Relation to immune profile
Publication date: Available online 8 February 2020Source: The Egyptian RheumatologistAuthor(s): Melike Ö Koç, Hasan Dursun, Bahar Kural, Sami HatipoğluAbstractAim of the workThe aim of this work was to study the pattern of immunoglobulin A (IgA) vasculitis organ involvement distribution in a cohort of patients in Turkey and to determine the relation to immune profile biomarkers.Patients and methodsTwo hundred and sixteen IgA vasculitis children were evaluated. Demographic characteristics, organ involvements, laboratory findings and immunological factors accompanying joint, gastrointestinal tract (GIT) and rena...
Source: The Egyptian Rheumatologist - February 9, 2020 Category: Rheumatology Source Type: research

A 13-year-old systemic lupus erythematosus girl initially presenting with Raccoon eyes and neuropsychiatric manifestations
ConclusionSLE may present with Raccoon eyes. Rapid detection and treatment of the disease based on clinical symptoms is critical for these patients. Prednisolone and cyclophosphamide are the best choice for treatment of the disease in children. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - February 8, 2020 Category: Rheumatology Source Type: research

Association between serum Toll-like receptor 4 and 8-hydroxy-2′-deoxyguanosine levels with disease activity in rheumatoid arthritis patients
Publication date: Available online 5 February 2020Source: The Egyptian RheumatologistAuthor(s): Mehrzad Hajialilo, Amir Ghorbanihaghjo, Saeede Maddahi, Alireza Khabbazi, Aida Malek Mahdavi, Nadereh RashtchizadehAbstractAim of the workConsidering the importance of toll-like receptor (TLR) 4 and oxidative stress in the pathogenesis of autoimmune disorders, present study was designed to assess serum TLR4, 8-hydroxy-2′-deoxyguanosine (8-OHdG) as a marker of oxidative DNA damage, and total antioxidant capacity (TAC) in rheumatoid arthritis (RA) patients and to study their relation with disease activity and their predictiv...
Source: The Egyptian Rheumatologist - February 6, 2020 Category: Rheumatology Source Type: research

Takayasu’s arteritis presenting in a pregnant woman with ankylosing spondylitis: Case report and review of the literature
ConclusionBoth TA and AS have no significant adverse effects on pregnancy if diagnosed and timely treated properly. When they occur concomitantly, more attention and care is needed to prevent complications. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - January 15, 2020 Category: Rheumatology Source Type: research

Treatment response and progression to end stage renal disease in adolescents and young adults with lupus nephritis: A follow up study in an Egyptian cohort
Publication date: Available online 10 January 2020Source: The Egyptian RheumatologistAuthor(s): Maryam A. Abdulrahman, Dina E. SallamAbstractBackgroundLupus nephritis (LN) badly affects the outcome in adolescents and young adults with systemic lupus erythematosus (SLE). Many have renal disease at onset and the significance of remission and relapse in adolescents and young adults is poorly evaluated.Aim of workTo outline the clinical and laboratory characteristics of treatment resistance, renal relapse and progression to end-stage renal disease (ESRD) in adolescents and young adults with LN.Patients and methodsEighty-five b...
Source: The Egyptian Rheumatologist - January 11, 2020 Category: Rheumatology Source Type: research

Pregnancy outcome in a cohort of Egyptian women with rheumatoid arthritis
Publication date: Available online 13 December 2019Source: The Egyptian RheumatologistAuthor(s): Maryam Ahmed Abdulrahman, Samah A. Elbakry, Nagham Safwat Samy, Rehab M. Abdelrahman, Nermeen SamyAbstractBackgroundFemale patients with rheumatoid arthritis (RA) can have successful pregnancies. However, those who experience a higher disease activity during pregnancy and require continued treatment have a potential risk of maternal and neonatal complications.Aim of the workTo assess pregnancy outcome (adverse maternal and neonatal outcomes) in an Egyptian cohort of female RA patients.Patients and methodsThiscross-sectional stu...
Source: The Egyptian Rheumatologist - December 14, 2019 Category: Rheumatology Source Type: research

Potential role of brain biomarkers in primary knee osteoarthritis patients using magnetic resonance spectroscopy
Publication date: Available online 10 December 2019Source: The Egyptian RheumatologistAuthor(s): Amany R. El-Najjar, Shimaa M. Abdelwhab, ahmad A. elsammakAbstractBackgroundPain in osteoarthritis (OA) primarily results from tissue damage but its' intensity does not essentially parallel the extent of joint destruction or presence of active inflammation, thus suggesting the likely involvement of a central component. The mid-anterior cingulate cortex (mACC) has an important role in pain perception, intensity and progression. In OA, low mACC γ-aminobutyric acid (GABA) was associated with high pain suggesting a role of pr...
Source: The Egyptian Rheumatologist - December 11, 2019 Category: Rheumatology Source Type: research

Hughes-Stovin syndrome without venous involvement – Unusual presentation of a rare disease: Case report and review of the literature
ConclusionHSS is a rare type of vasculitis, which can present with arterial, venous and/or intracardiac thrombosis even without other systemic manifestations. HSS can present without venous involvement. HSS require aggressive immune suppressive treatment, however anticoagulation and surgery can be attempted when indicated. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - October 26, 2019 Category: Rheumatology Source Type: research

Nailfold capillaroscopic changes in Egyptian patients with psoriatic arthritis in comparison to rheumatoid arthritis
Publication date: October 2019Source: The Egyptian Rheumatologist, Volume 41, Issue 4Author(s): Adel M. Ali, Sherin M. Hamza, Fatma M. Aboud, Nouran M. El-ShahatAbstractIntroductionNailfold capillaroscopy (NFC) is simple technique for assessment of the microvascular changes recognized in both diseases can be used in helping the differential diagnosis.Aim of the workTo determine the nailfold capillaroscopic changes in psoriatic arthritis (PsA) and rheumatoid arthritis (RA) patients and their relation to disease activity.Patients and methodsTwenty PsA and 20 RA patients were studied. Disease activity score (DAS28) was assess...
Source: The Egyptian Rheumatologist - October 25, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: October 2019Source: The Egyptian Rheumatologist, Volume 41, Issue 4Author(s): (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - October 25, 2019 Category: Rheumatology Source Type: research

Soluble CCN2/connective tissue growth factor levels in Egyptian systemic sclerosis patients: Possible association with cutaneous and pulmonary fibrosis
ConclusionThe work indicates the importance of CCN2 in cutaneous and pulmonary fibrosis in patients with SSc especially those with diffuse subtype. An additional prospective large scale, a longitudinal study should be carried out to support these findings and to reveal the mechanistic connections between CCN-2 levels and SSc disease manifestations. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - October 22, 2019 Category: Rheumatology Source Type: research

Neutrophil/lymphocyte and platelet/lymphocyte ratios are useful predictors comparable to serum IL6 for disease activity and damage in naive and relapsing patients with lupus nephritis
ConclusionNLR and PLR appear to be potentially useful cheap parameters of activity, relapse and severity in SLE patients with nephritis. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - September 15, 2019 Category: Rheumatology Source Type: research

Significance of calgranulins (S100A8, S100A9 and S100A12), ferritin and toll-like receptor 4 in juvenile idiopathic arthritis children
ConclusionsS100A8, S100A9 and ferritin were upregulated in sera of JIA patients. Their significance as predicting biomarkers of disease outcome was augmented, especially in CRP- and RF-seropositive, low JADAS27 and persistent oligoarticular JIA patients. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - September 1, 2019 Category: Rheumatology Source Type: research

Therapeutic potential of perineural injection for temporomandibular joint pain, dysfunction and musculoskeletal ultrasound findings in rheumatoid arthritis patients
Publication date: Available online 30 August 2019Source: The Egyptian RheumatologistAuthor(s): Hanan M. Elshoura, Nayera Z. Saber, Mohamed A. Elwy, Mervat M. AbdelhakimAbstractAim of the workTo assess the effectiveness of perineural injection therapy (PIT) as a new modality in the management of chronic pain and dysfunction of the TMJ in RA patients and to study if it has any role in tissue regeneration.Patients and methodsOut of 19 RA patients with persistent TMJ involvement and pain despite receiving systemic treatment, 13 agreed to have PIT and only 11 completed the study; 21 TMJ (10 bilateral and 1 unilateral) were asse...
Source: The Egyptian Rheumatologist - September 1, 2019 Category: Rheumatology Source Type: research

Potential anti-inflammatory action of resveratrol and piperine in adjuvant-induced arthritis: Effect on pro-inflammatory cytokines and oxidative stress biomarkers
ConclusionCo-administration of PIP enhanced the anti-inflammatory efficacy of RSV in the arthritic-induced rats. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - August 30, 2019 Category: Rheumatology Source Type: research

Short term effect of non-steroidal anti-inflammatory drugs on clinical and magnetic resonance imaging of the sacroiliac joints progression in axial spondyloarthritis patients
Publication date: Available online 21 August 2019Source: The Egyptian RheumatologistAuthor(s): Abeer Abdelati, Mona Helmy, Mohamed Barakat, Fatma-Alzahraa AbdallahAbstractAim of the workTo evaluate the short term effect of maximally tolerated dose of non-steroidal anti-inflammatory drugs (NSAIDs) on disease activity and radiographic progression of axial spondyloarthritis (axSpA) patients.Patients and methodsA six-week prospective study on thirty patients with active axSpA. All patients were assessed at baseline visit, a follow-up visit after 2 weeks, and 6 weeks of treatment with a maximally tolerated dose of NSAID. Di...
Source: The Egyptian Rheumatologist - August 23, 2019 Category: Rheumatology Source Type: research

New promising avenue for the simvastatin combination with residronate, strontium ranelate and raloxifene in experimentally-induced osteoporosis
Publication date: Available online 24 July 2019Source: The Egyptian RheumatologistAuthor(s): Amira K. Khalifa, Sohier A. Diab, Ghada M. Hashem, Essam F. Alalkamy, Mira F. YacoubAbstractAim of the workThis is the first experimental study to assess the possible synergistic effects of simvastatin combination with residronate, strontium ranelate and raloxifene on glucocorticoid induced osteoporosis (GIO) in female albino rats.Materials and methods48 mature healthy female albino rats were randomly allocated into 6 main groups (8 rats /group) and received all drugs daily orally for 6 weeks. (G1) negative control group; (G2) os...
Source: The Egyptian Rheumatologist - July 25, 2019 Category: Rheumatology Source Type: research

Micro RNA 499 gene expression and interleukin 17 in Egyptian patients with Behçet’s disease
Publication date: Available online 22 July 2019Source: The Egyptian RheumatologistAuthor(s): Dina F. Elessawi, Nashwa K. Radwan, Neveen M. Nosseir, Mohamed S. TawfikAbstractBackgroundHigh levels of interleukin 17 are expressed in active Behcet’s disease (BD) patients. High miRNA-499 relative expression is known to be associated with vascular manifestations and aneurysms in BD.Aim of the workTo detect miRNA-499 relative expression and interleukin 17 serum levels in BD patients and find their association to clinical characteristics and disease activity.Patients and methodsBlood samples were obtained from 40 Egyptian BD...
Source: The Egyptian Rheumatologist - July 23, 2019 Category: Rheumatology Source Type: research

Dysregulation of microRNA146a-5p expression in systemic lupus erythematosus females: Diagnostic potential and association with ocular manifestations
ConclusionThese findings suggest that miR-146a-5p could be a potential diagnostic biomarker in SLE and may implicate a functional role in the pathophysiology of the ocular manifestations in the disease. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 20, 2019 Category: Rheumatology Source Type: research

Association between serum homocysteine and arterial stiffness in patients with Behçet’s disease
Publication date: Available online 16 July 2019Source: The Egyptian RheumatologistAuthor(s): Amany R. El-Najjar, ahmed A. elsammakAbstractAim of the workTo study the effects of serum homocysteine (Hcy) on arterial wall properties, as a contributing risk factor for arterial atherosclerosis and thrombosis.Patients and methodsFifty Behçet's disease (BD) patients (M/F:37/13; age:34.8 ± 8.5 years) along with 50 healthy controls (M/F:32/18; age:31.9 ± 8.1 years) matched for age, sex, blood pressure, heart rate, height, total cholesterol and glucose levels were included. All were recruited Zagazig...
Source: The Egyptian Rheumatologist - July 17, 2019 Category: Rheumatology Source Type: research

Depression in rheumatoid arthritis patients: Screening for a frequent yet underestimated comorbidity
This study included 200 consecutive adult RA patients. Clinical and laboratory investigations were performed. PROs including tender and swollen joint count, patient’s estimated pain, patient global assessment (PGA), validated Arabic version of the health assessment questionnaire (HAQ-A) as well as physician global assessment were considered. The disease activity score (DAS28) and simplified erosion narrowing score (SENS) were calculated. Patient health questionnaire-9 (PHQ-9) was used to detect depression.ResultsThe patients’ mean age was 41.3 ± 11.9 years and disease duration 6.6 ± 4.9...
Source: The Egyptian Rheumatologist - July 13, 2019 Category: Rheumatology Source Type: research

Polyarteritis nodosa (PAN) associated with familial Mediterranean fever (FMF): An unusual case presentation and a review of the literature
ConclusionIncreased awareness of such clinical association of PAN and FMF and early management may improve the disease outcome. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 9, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: July 2019Source: The Egyptian Rheumatologist, Volume 41, Issue 3Author(s): (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 3, 2019 Category: Rheumatology Source Type: research

Risk factors for cataracts in a cohort of Egyptian systemic lupus erythematosus patients
This study was undertaken to evaluate cataract risk factors in Egyptian systemic lupus erythematosus (SLE) patients.Patients and methodsA cohort of 150 consecutive adult SLE patients was included. None of the patients was diabetic or had cataract before steroids treatment for SLE. Detailed medical and ophthalmological histories were taken. Thorough clinical examination was performed with assessment of SLE disease activity index (SLEDAI) and systemic lupus international collaborating clinics damage index (SLICC DI), along with routine blood tests. Slit lamp examination was done to assess the anterior segment of the eye espe...
Source: The Egyptian Rheumatologist - July 3, 2019 Category: Rheumatology Source Type: research

Bone mineral density and bone remodelling in Tunisian patients with ankylosing spondylitis: A cross-sectional study
Publication date: Available online 29 June 2019Source: The Egyptian RheumatologistAuthor(s): Afef Feki, Hela Fourati, Imen Sellami, Zouhour Gassara, Achraf Ghorbel, Mariam Ezzeddine, Hedi Kallel Mohamed, Fatma Ayadi, Rim Akrout, Sofien BakloutiAbstractAim of the workTo assess the bone turnover markers and bone mineral density (BMD) in ankylosing spondylitis (AS) patients and to evaluate their association with clinical variables.Patients and methodsForty-seven AS patients were compared with 47 matched control. Clinical features and inflammatory parameters were assessed. C-terminal telopeptide fragments of type I collagen (C...
Source: The Egyptian Rheumatologist - June 30, 2019 Category: Rheumatology Source Type: research

Predictive significance of CXCL8, CXCL10 and CXCL16 in juvenile idiopathic and rheumatoid arthritis Iraqi patients
ConclusionsCXCL8 and CXCL10 are potential predictors of JIA and RA. CXCL10 is a more significant predictor. The CXCL16 was not found to have such impact and it might be of value in a subgroup of seropositive RA patients. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - June 15, 2019 Category: Rheumatology Source Type: research