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Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters. [time-...
Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news

A pilot study of the ticagrelor role in ischemic stroke secondary prevention
Conclusion: Ticagrelor was noninferior to aspirin regarding safety profile. Compared with aspirin, ticagrelor had a better clinical outcome based on NIHSS and mRS in first-ever acute ischemic stroke patients who received it within 9 h from symptom onset, leading to a shorter hospital stay.Eur Neurol
Source: European Neurology - August 30, 2021 Category: Neurology Source Type: research

Clinical and Radiological Characteristics of Acute Cerebrovascular Diseases Among Egyptian Patients With COVID-19 in Upper Egypt
Conclusion: Acute CVD among patients with COVID-19 was common in our study. LVO was the commonest. Hypertension, IHD, and anemia are the most common risk factors and could contribute to the worsening of clinical presentation. Comorbidities were common among patients with CVD, although a large number had elevated liver enzymes and creatinine that were partially due to COVID-19 infection itself. The current results begin to characterize the spectrum of CVD associated with COVID-19 in patients in Upper Egypt.Registration ID: The ID number of this study is IRB no: 17300470.
Source: Frontiers in Neurology - March 22, 2021 Category: Neurology Source Type: research

Surveillance Study of Acute Neurological Manifestations among 439 Egyptian Patients with COVID-19 in Assiut and Aswan University Hospitals
Conclusion: In COVID-19, both the CNS and PNS are affected. Stroke was the most common complication for CNS, and anosmia and/or ageusia were common for PNS diseases. However, there were 6 cases of encephalitis, 2 cases of spinal cord myelopathy, 2 cases of MG, and 2 cases of myositis.Neuroepidemiology
Source: Neuroepidemiology - February 25, 2021 Category: Epidemiology Source Type: research

Cinnamon May Slow Progression To Type 2 Diabetes, Boston Study Finds
(CNN) — Cinnamon may improve blood sugar control in people with a condition known as prediabetes and may slow the progression to type 2 diabetes, according to a new pilot study of 51 people with elevated blood sugars. “We are looking for safe, durable and cost-effective approaches to reduce the progression from prediabetes to type 2 diabetes,” said study author Dr. Giulio Romeo, a staff physician at Boston’s Joslin Diabetes Center and the division of endocrinology at Beth Israel Deaconess Medical Center. The study published Tuesday in the Journal of the Endocrine Society. “Our 12-week study sh...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 21, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston Cinnamon CNN Diabetes Source Type: news

World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions
Publication date: Available online 2 September 2019Source: The Lancet Global HealthAuthor(s): Stephen Kaptoge, Lisa Pennells, Dirk De Bacquer, Marie Therese Cooney, Maryam Kavousi, Gretchen Stevens, Leanne Margaret Riley, Stefan Savin, Taskeen Khan, Servet Altay, Philippe Amouyel, Gerd Assmann, Steven Bell, Yoav Ben-Shlomo, Lisa Berkman, Joline W Beulens, Cecilia Björkelund, Michael Blaha, Dan G Blazer, Thomas BoltonSummaryBackgroundTo help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort to develop, evaluate, and illustrate revised risk models. ...
Source: The Lancet Global Health - September 4, 2019 Category: International Medicine & Public Health Source Type: research

A Novel Homozygous Non-sense Mutation in the Catalytic Domain of MTHFR Causes Severe 5,10-Methylenetetrahydrofolate Reductase Deficiency
Conclusion: We identified a novel non-sense mutation in MTHFR gene in a single Egyptian family with severe MTHFR deficiency. The present investigation is clinically important, as it adds to the growing list of MTHFR mutations, which might help in genetic counseling of families of affected children and proper genotype-phenotype correlation. Background Severe 5,10-Methylenetetrahydrofolate reductase (MTHFR; OMIM 236250) deficiency is a rare inborn error of metabolism and inherited in an autosomal recessive fashion. It is a very common disorder of folate metabolism and is clinically characterized with low plasma methion...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

World No Tobacco Day 2018: Tobacco breaks hearts
Cairo, Egypt, 31 May – Every year, on 31 May, the World Health Organization (WHO) and partners mark World No Tobacco Day, highlighting the health and other risks associated with tobacco use, and advocating for effective policies to reduce tobacco consumption. This year, World No Tobacco Day focuses on tobacco and heart disease. The campaign’s slogan is “Tobacco breaks hearts. Choose health, not tobacco”. Tobacco use is one of the leading causes of premature death and disability worldwide. It is also a key risk factor for the development of coronary heart disease, stroke and peripheral vascular disease. “In most ...
Source: WHO EMRO News - May 26, 2018 Category: Middle East Health Source Type: news

Primary PCI versus Pharmaco-Invasive Strategy in Patients with ST-Elevation Myocardial Infarction; a Randomized Clinical Study
Conclusion: Immediate fibrinolysis followed by coronary angiography 3-24 hr later resulted in similar short term outcome and earlier effective reperfusion in patients with STEMI compared to PPCI.Keywords:Fibrinolysis,PCI,Reperfusion,STEMIView:PDF (323.13 KB)Click here to download the PDF file.‹ Probability of Dying and Survival Analysis of Diabetic and/Hypertensive Patients Who Undergone Hemodialysis with Heart Disease Complication: A Comparison between a Hemodialysis Center Jakarta, Indonesia and Penang, MalaysiaAssessment of Risk Factors for the Cardiovascular Diseases in People Visiting a Tertiary Care Hospital for Ro...
Source: Journal of Cardiovascular Disease Research - March 8, 2018 Category: Cardiology Authors: yunus Source Type: research

Economic Evaluation For Establishing Stroke Unit Followed By Early Supported Discharge In Egypt
When Stroke accounts for 6 ·4% of all deaths and thus ranks 3rd after heart disease&gastrointestinal with a crude prevalence rate of 963/100 000 inhabitants. The clinical characteristics of Egyptian stroke patients are generally similar to those in other populations. Exceptions may include the higher prevalence of vascular risk factors and a younger mean age of stroke patients (4, 18 –20). Due to those facts stroke&its complications may be one of the major economic challenges facing Egyptian health sector.
Source: Value in Health - October 1, 2017 Category: International Medicine & Public Health Authors: A Abotaleb Source Type: research

Clinical characteristics and management of hospitalized and ambulatory patients with heart failure–results from ESC heart failure long‐term registry–Egyptian cohort
ConclusionPatients in the Egyptian cohort exhibited distinct features from HF patients in other countries in the ESC‐HF Long‐term Registry.
Source: ESC Heart Failure - June 1, 2015 Category: Cardiology Authors: Mahmoud Hassanein, Magdy Abdelhamid, Bassem Ibrahim, Ahmed Elshazly, Mohamed Wafaie Aboleineen, Hesham Sobhy, Gamela Nasr, Fatma Elmesseiry, Ahmed Abdelmoniem, Medhat Ashmawy, Nabil Farag, Amr Youssef, Atef Elbahry, Yahia Elrakshy, Mohamed Sobhy, Tarek M. Tags: Original Research Article Source Type: research