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Total 170 results found since Jan 2013.
The Effect of Home Care for Stroke Patients and Education of Caregivers on the Caregiver Burden and Quality of Life.
This study results indicated that home care provided for stroke patients and education of caregivers decreased the caregiver burden and increased their quality of life.
PMID: 31819329 [PubMed - in process]
Source: Acta Clinica Croatica - December 11, 2019 Category: General Medicine Tags: Acta Clin Croat Source Type: research
Adipose-derived mesenchymal stem cells attenuate ischemic brain injuries in rats by modulating miR-21-3p/MAT2B signaling transduction.
CONCLUSION: This study confirmed the protective effect of ADMSCs against ischemic brain injury exerted by suppressing miR-21-3p level and up-regulating MAT2B level.
PMID: 31686458 [PubMed - in process]
Source: Croatian Medical Journal - October 30, 2019 Category: General Medicine Authors: Li C, Fei K, Tian F, Gao C, Yang S Tags: Croat Med J Source Type: research
Necroptosis is one of the modalities of cell death accompanying ischemic brain stroke: from pathogenesis to therapeutic possibilities.
Abstract
Due to very limited therapeutic options, ischemic brain injury is one of the leading causes of death and lifelong disability worldwide, which imposes enormous public health burden. One of the main events occurring with ischemic brain stroke is cell death. Necroptosis is a type of cell death described as a regulated necrosis characterized by cell membrane disruption mediated by phosphorylated mixed lineage kinase like protein (MLKL). It can be triggered by activation of death receptors (eg, FAS, TNFR1), which lead to receptor-interacting serine/threonine-protein kinase 3 (RIPK3) activation by RIPK1 in the ...
Source: Croatian Medical Journal - April 29, 2019 Category: General Medicine Authors: Hribljan V, Lisjak D, Petrović DJ, Mitrečić D Tags: Croat Med J Source Type: research
Neuroprotective and reparative effects of endoplasmic reticulum luminal proteins - mesencephalic astrocyte-derived neurotrophic factor and cerebral dopamine neurotrophic factor.
Abstract
Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) are proteins that have received increasing attention in the last decades. Although they are called neurotrophic factors they are drastically different from neurotrophic factors in their expression and physiological actions. They are located in the lumen of the endoplasmic reticulum (ER) and their basal secretion from neurons is very low. However their secretion is stimulated upon ER calcium depletion by chemical probes such as thapsigargin, a sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump inhi...
Source: Croatian Medical Journal - April 29, 2019 Category: General Medicine Authors: Albert K, Airavaara M Tags: Croat Med J Source Type: research
Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research
Transplantation of neural stem cells in the mouse model of ischemic brain stroke and expression of genes involved in programmed cell death.
Abstract
PMID: 30394012 [PubMed - in process]
Source: Croatian Medical Journal - October 31, 2018 Category: General Medicine Authors: Hribljan V, Salamon I, Đemaili A, Alić I, Mitrečić D Tags: Croat Med J Source Type: research
The Impact of Comorbidity on Rehabilitation Outcome after Ischemic Stroke.
Authors: Simić-Panić D, Bošković K, Milićević M, Rabi Žikić T, Cvjetković Bošnjak M, Tomašević-Todorović S, Jovićević M
Abstract
Comorbidity decreases survival but it still remains unknown to what extent functional recovery after ischemic stroke is affected. The aim of this research was to determine the prevalence of the most common comorbidities in patients with ischemic stroke and to examine their predictive value on the functional status and recovery. In order to obtain relevant information for this research, we conducted a prospective study over a two-year period. It included patients with acute/...
Source: Acta Clinica Croatica - September 27, 2018 Category: General Medicine Tags: Acta Clin Croat Source Type: research
Distribution of Stroke Risk Factors in Eastern Croatia.
Authors: Rostohar Bijelić B, Petek M, Kadojić M, Bijelić N, Kadojić D
Abstract
The aim of this study was to determine the distribution of risk factors according to age, gender, subtypes and recurrence of stroke in eastern Croatia. The study included 250 acute stroke patients admitted to University Department of Neurology, Osijek University Hospital Centre in 2011. Patients were grouped according to age, gender, subtypes and recurrence of stroke. The study showed significant differences in the distribution of cigarette smoking, diabetes, cardiomyopathy and hyperuricemia according to patient age. According to gen...
Source: Acta Clinica Croatica - September 27, 2018 Category: General Medicine Tags: Acta Clin Croat Source Type: research
Evaluation of the Head Multislice Computed Tomography Scan in Emergency Department.
Authors: Zadravec D, Gregurić T, Smoljan M, Mustapić M, Miličić G, Jović A, Rubil D, Tomasović D, Bašić Kes V
Abstract
The aim of the study was to examine the prevalence of head injuries, acute stroke and brain tumors obtained from computed tomography (CT) scans in the emergency department (ED) during a one-year period. We also assessed the potential effect of seasons on the occurrence of stroke, head trauma and tumors found on CT scans, expressed in monthly intervals. This retrospective review included all patients that underwent emergency head CT from the hospital database. A total of 3888 head CT examina...
Source: Acta Clinica Croatica - March 1, 2018 Category: General Medicine Tags: Acta Clin Croat Source Type: research
Disease characteristics and causes of early and late death in a group of Croatian patients with systemic lupus erythematosus deceased over a 10-year period.
CONCLUSION: Although stroke occurred both in the early and late disease course, it was primarily associated with LD. Given the low proportion of SLE recorded in death certificates of deceased SLE patients, matching of institutional and vital statistics records may be required to assess the true impact of SLE on mortality.
PMID: 29498492 [PubMed - in process]
Source: Croatian Medical Journal - February 28, 2018 Category: General Medicine Authors: Padjen I, Cerovec M, Erceg M, Mayer M, Stevanović R, Anić B Tags: Croat Med J Source Type: research
Comparison of RISK-PCI, GRACE, TIMI risk scores for prediction of major adverse cardiac events in patients with acute coronary syndrome.
CONCLUSIONS: In comparison with the GRACE and TIMI scores, RISK-PCI score showed a non-inferior ability to predict 30-day MACE and death in ACS patients. Moreover, RISK-PCI was the only scoring system that could predict recurrent ischemia requiring TVR.
PMID: 29308832 [PubMed - in process]
Source: Croatian Medical Journal - December 31, 2017 Category: General Medicine Authors: Jakimov T, Mrdović I, Filipović B, Zdravković M, Djoković A, Hinić S, Milić N, Filipović B Tags: Croat Med J Source Type: research
Serum neuron-specific enolase as a marker of brain ischemia-reperfusion injury in patients
undergoing carotid endarterectomy.
SERUM NEURON-SPECIFIC ENOLASE AS A MARKER OF BRAIN ISCHEMIA-REPERFUSION INJURY IN PATIENTS
UNDERGOING CAROTID ENDARTERECTOMY.
Acta Clin Croat. 2016 12;55(4):579-84
Authors: Iłżecki M, Iłżecka J, Przywara S, Terlecki P, Grabarska A, Stepulak A, Zubilewicz T
Abstract
In patients with atherosclerotic stenosis of the extracranial segment of internal
carotid artery, surgical intervention is an effective method to prevent cerebral ischemic stroke. However,
this surgical procedure may cause vascular brain damage. The aim of the study was to investigate
consequential brain ischemia-reperfusion injury by me...
Source: Acta Clinica Croatica - November 10, 2017 Category: General Medicine Tags: Acta Clin Croat Source Type: research
A combination of levobupivacaine and lidocaine for paravertebral block in breast cancer patients undergoing quadrantectomy causes greater hemodynamic oscillations than levobupivacaine alone.
CONCLUSION: The use of 0.5% levobupivacaine in comparison with 0.5% levobupivacaine with 2% lidocaine solution for PVB had a longer time-to-block onset, but it also reduced hemodynamic disturbances and prolonged the analgesic effect.
PMID: 28857520 [PubMed - in process]
Source: Croatian Medical Journal - August 31, 2017 Category: General Medicine Authors: Župčić M, Graf Župčić S, Duzel V, Šimurina T, Šakić L, Fudurić J, Peršec J, Milošević M, Stanec Z, Korušić A, Barišin S Tags: Croat Med J Source Type: research
Rasch validation and comparison of Slovenian, Croatian, and Italian versions of the Mini-BESTest in patients with subacute stroke
We aimed to verify by Rasch analysis whether the Mini-BESTest, a balance measure, confirms its main psychometric properties in patients with subacute stroke undergoing rehabilitation in three different countries (Slovenia, Croatia, and Italy), and to examine the stability of item hierarchy and difficulty across the three national versions through a differential item functioning analysis. We investigated 159 patients with subacute stroke consecutively admitted to three rehabilitation facilities after screening for an intensive, tailored rehabilitation program. Balance function was tested within 36 h from admission and aft...
Source: International Journal of Rehabilitation Research - August 12, 2017 Category: Rehabilitation Tags: Original articles Source Type: research
The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey
ConclusionsNOACs are increasingly used in AF patients in the Balkan Region, but NOAC use is predominantly guided by factors other than evidence-based decision-making (e.g., drug availability on the market or reimbursement policy). Efforts are needed to establish an evidence-based approach to OAC selection and to facilitate the optimal use of OAC, thus improving the outcomes in AF patients in this large region.
Source: Advances in Therapy - August 9, 2017 Category: Drugs & Pharmacology Source Type: research
