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Significant delay and decreased chance of treatment for acute ischemic stroke patients on remote outer islets of China compared with the main island: the PUTUO Study
CONCLUSION: The diagnosis and treatment of acute ischemic stroke patients from OIs was significantly postponed compared to those from MI. Therefore, new effective and efficient solutions are urgently needed.PMID:37280101 | DOI:10.22605/RRH7574
Source: Rural and Remote Health - June 6, 2023 Category: Rural Health Authors: Bangbo Xia Ning Liu Li Hu Hongyi Zhu Bifeng Zhong Zhongheng Zhang Jian Lin Yong Kang Source Type: research

Development and validation of a novel radiomics-clinical model for predicting post-stroke epilepsy after first-ever intracerebral haemorrhage
ConclusionsThe combined radiomics-clinical model was better able to predict ICH-associated PSE compared to the clinical model. This can help clinicians better predict an individual patient ’s risk of PSE following a first-ever ICH and facilitate earlier PSE diagnosis and treatment.Key Points•Radiomics has not been used in predicting the risk of developing PSE.•Higher Rad-scores were associated with higher risk of developing PSE.•The combined model showed better performance of PSE prediction ability.
Source: European Radiology - February 3, 2023 Category: Radiology Source Type: research

Analysis of Chinese Medical Syndrome Features of Ischemic Stroke Based on Similarity of Symptoms Subgroup
ConclusionsThere were 7 main symptom similarity-based subgroups in ischemic stroke patients, and their specific characteristics were obvious. The main syndromes were wind phlegm pattern and hyperactivity of Gan yang pattern.
Source: Chinese Journal of Integrative Medicine - June 20, 2022 Category: Internal Medicine Source Type: research

Analysis of HLA Variants and Graves ’ Disease and Its Comorbidities Using a High Resolution Imputation System to Examine Electronic Medical Health Records
Hyperthyroidism is a prevalent endocrine disorder, and genetics play a major role in the development of thyroid-associated diseases. In particular, the inheritance of HLA has been demonstrated to induce the highest susceptibility to Graves’ disease (GD). However, thus far, no studies have reported the contribution of HLA to the development of GD and the complications that follow. Thus, in the present study, to the best of our knowledge, for the first time, a powerful imputation method, HIBAG, was used to predict the HLA subtypes among populations with available genome-wide SNP array data from the China Medical University...
Source: Frontiers in Endocrinology - March 7, 2022 Category: Endocrinology Source Type: research

Using the Symptom Patient Similarity Network to Explore the Difference between the Chinese and Western Medicine Pathways of Ischemic Stroke and its Comorbidities
CONCLUSION: The research of disease classification based on community detection of symptom-shared patient networks is practical; the common molecular pathway of symptoms and herbs reflects the rationality of TCM herbs on symptoms and the wide range of therapeutic targets.PMID:34899950 | PMC:PMC8654542 | DOI:10.1155/2021/4961738
Source: Evidence-based Complementary and Alternative Medicine - December 13, 2021 Category: Complementary Medicine Authors: Lunzhong Zhang Shu Han Manli Zhao Runshun Zhang Xuebin Zhang Jing Zhang Xiaoqing Liu Yuyao He Zhao He Yunfang Dong Xiaoying Hou Zijun Mou Liyun He Hong Zhou Jie Yang Xingyan Huang Yanjie Hu Yuefeng Zhang Lili Zhang Zhengguang Chen Xiaozhen Li Yan Tan Kega Source Type: research

Impacts of type 2 diabetes mellitus and hypertension on the incidence of cardiovascular diseases and stroke in China real-world setting: a retrospective cohort study
Conclusion T2DM and HTN were strongly associated with combined VE and stroke risk; however, the HTN-only group had a higher combined VE and stroke risk than the T2DM-only group.
Source: BMJ Open - November 29, 2021 Category: General Medicine Authors: Liu, Y., Li, J., Dou, Y., Ma, H. Tags: Open access, Diabetes and Endocrinology Source Type: research

Spectrum of Neuropsychiatric Manifestations in COVID-19.
Abstract Corona Virus Disease 2019 (COVID-19) emerged in December 2019 from Wuhan, China. It typically presents with mild upper respiratory tract infection symptoms and may have life threatening complications, including acute respiratory distress syndrome, acute stroke, myocardial infarction, kidney failure, shock, and even death. Coronavirus infections are known to have neuroinvasive potential with consequent neuropsychiatric manifestations. We analyzed COVID-19 adult patients in the TriNetX database, which is a global health collaborative clinical research platform collecting real-time electronic medical records...
Source: Brain, Behavior, and Immunity - June 15, 2020 Category: Neurology Authors: Nalleballe K, Reddy Onteddu S, Sharma R, Dandu V, Brown A, Jasti M, Yadala S, Veerapaneni K, Siddamreddy S, Avula A, Kapoor N, Mudassar K, Kovvuru S Tags: Brain Behav Immun Source Type: research

New-Onset Geriatric Epilepsy in China: A Single-Center Study.
Conclusions: Autoimmune encephalitis is becoming an increasing risk factor of subsequent epilepsy in older people. Older patients with new epilepsy are more likely to respond to antiepileptic drugs, and drug-resistant epilepsy is uncommon. PMID: 30539903 [PubMed - in process]
Source: Chinese Medical Journal - December 14, 2018 Category: General Medicine Authors: Chen JH, Zhou XQ, Lu Q, Jin LR, Huang Y Tags: Chin Med J (Engl) Source Type: research