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Condition: Diabetes
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Total 188 results found since Jan 2013.

Aerobic Training in Canadian Stroke Rehabilitation Programs.
CONCLUSIONS: Most stroke rehabilitation programs across Canada include AT. People with severe physical impairment and those with cardiac, metabolic, and hemodynamic comorbidities may be excluded or not appropriately monitored during exercise. More detailed guidelines and training practices are needed to address these challenges.Video Abstract available for more insights from the authors (see Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A233). PMID: 30138234 [PubMed - as supplied by publisher]
Source: Physical Therapy - August 22, 2018 Category: Physiotherapy Authors: Nathoo C, Buren S, El-Haddad R, Feldman K, Schroeder E, Brooks D, Inness EL, Marzolini S Tags: J Neurol Phys Ther Source Type: research

Stroke and Coronary Artery Disease Are Associated With Parkinson's Disease.
CONCLUSIONS: Our study suggested that stroke and CAD are associated with PD in two Chinese population-based cohorts, indicating a probable vascular component in the pathogenesis of PD. PMID: 30001757 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - July 13, 2018 Category: Neurology Authors: Li Q, Wang C, Tang H, Chen S, Ma J Tags: Can J Neurol Sci Source Type: research

Importance of Considering Competing Risks in Time-to-Event Analyses: Application to Stroke Risk in a Retrospective Cohort Study of Elderly Patients With Atrial Fibrillation Original Articles
Conclusions: The incidence of death without stroke was 9-fold higher than that of stroke, leading to biased estimates of stroke risk with traditional time-to-event methods. Statistical methods that appropriately account for competing risks should be used to mitigate this bias.
Source: Circulation: Cardiovascular Quality and Outcomes - July 11, 2018 Category: Cardiology Authors: Abdel-Qadir, H., Fang, J., Lee, D. S., Tu, J. V., Amir, E., Austin, P. C., Anderson, G. M. Tags: Atrial Fibrillation, Epidemiology, Primary Prevention, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study
Publication date: 30 June–6 July 2018Source: The Lancet, Volume 391, Issue 10140Author(s): Duminda N Wijeysundera, Rupert M Pearse, Mark A Shulman, Tom E F Abbott, Elizabeth Torres, Althea Ambosta, Bernard L Croal, John T Granton, Kevin E Thorpe, Michael P W Grocott, Catherine Farrington, Paul S Myles, Brian H Cuthbertson, Sophie Wallace, Bruce Thompson, Mathew Ellis, Brigette Borg, Ross K Kerridge, Jeanene Douglas, John BrannanSummaryBackgroundFunctional capacity is an important component of risk assessment for major surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain accuracy...
Source: The Lancet - July 10, 2018 Category: General Medicine Source Type: research

Activated Mast Cells Mediate Low-Grade Inflammation in Type 2 Diabetes: Interleukin-37 Could be Beneficial
Publication date: Available online 31 January 2018Source: Canadian Journal of DiabetesAuthor(s): Pio Conti, Gianpaolo Ronconi, Spyridon K. Kritas, Alessandro Caraffa, Theoharis C. TheoharidesAbstractMast cells (MCs) promote guest immune responses to parasites and play a critical role in allergic and inflammatory reactions. Once they have been activated, MCs release highly inflammatory compounds that can provoke serious pathologic signs that can lead to death. MCs generate a number of preformed, de novo synthesized compounds and inflammatory cytokine/chemokine synthesis in response to the high-affinity (Kd=10–10 M) immuno...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

The Divergent Cardiovascular Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Type 1 Receptor Blockers in Adult Patients With Type 2 Diabetes Mellitus
Publication date: April 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 2Author(s): Martin H. Strauss, Alistair S. HallAbstractThe renin angiotensin aldosterone system (RAAS) plays a central role in the pathophysiology of hypertension and vascular disease. Angiotensin-converting enzyme inhibitors (ACEi's) suppress angiotensin II (ANG II) concentrations, whereas angiotensin II type 1 (AT1) receptor blockers (ARBs) block the binding of ANG II to AT1 receptors. ACEi's and ARBs are both effective antihypertensive agents and produce similar risk reductions for stroke, a blood pressure-dependent phenomenon. ACEi's als...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Factors Influencing Oral Anticoagulation Prescription for Patients Presenting to Emergency Departments With Atrial Fibrillation and Flutter
Publication date: June 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 6Author(s): Robert J.H. Miller, Derek S. Chew, Saman Rezazadeh, Sheila Klassen, Payam Pournazari, Eddy Lang, F. Russell QuinnAbstractAtrial fibrillation and atrial flutter (AF/AFL) are associated with an increased risk of stroke and systemic embolism. However, many patients are not started on guideline-recommended oral anticoagulation (OAC). We determined factors associated with initiation of OAC in eligible patients presenting to emergency departments. This retrospective cohort included patients with electrocardiogram (ECG)-documented AF/A...
Source: Canadian Journal of Cardiology - July 10, 2018 Category: Cardiology Source Type: research

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study
Publication date: 30 June–6 July 2018Source: The Lancet, Volume 391, Issue 10140Author(s): Duminda N Wijeysundera, Rupert M Pearse, Mark A Shulman, Tom E F Abbott, Elizabeth Torres, Althea Ambosta, Bernard L Croal, John T Granton, Kevin E Thorpe, Michael P W Grocott, Catherine Farrington, Paul S Myles, Brian H Cuthbertson, Sophie Wallace, Bruce Thompson, Mathew Ellis, Brigette Borg, Ross K Kerridge, Jeanene Douglas, John BrannanSummaryBackgroundFunctional capacity is an important component of risk assessment for major surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain accuracy...
Source: The Lancet - July 5, 2018 Category: General Medicine Source Type: research

The Divergent Cardiovascular Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Type 1 Receptor Blockers in Adult Patients With Type 2 Diabetes Mellitus
Publication date: April 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 2Author(s): Martin H. Strauss, Alistair S. HallAbstractThe renin angiotensin aldosterone system (RAAS) plays a central role in the pathophysiology of hypertension and vascular disease. Angiotensin-converting enzyme inhibitors (ACEi's) suppress angiotensin II (ANG II) concentrations, whereas angiotensin II type 1 (AT1) receptor blockers (ARBs) block the binding of ANG II to AT1 receptors. ACEi's and ARBs are both effective antihypertensive agents and produce similar risk reductions for stroke, a blood pressure-dependent phenomenon. ACEi's als...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Activated Mast Cells Mediate Low-Grade Inflammation in Type 2 Diabetes: Interleukin-37 Could be Beneficial
Publication date: Available online 31 January 2018Source: Canadian Journal of DiabetesAuthor(s): Pio Conti, Gianpaolo Ronconi, Spyridon K. Kritas, Alessandro Caraffa, Theoharis C. TheoharidesAbstractMast cells (MCs) promote guest immune responses to parasites and play a critical role in allergic and inflammatory reactions. Once they have been activated, MCs release highly inflammatory compounds that can provoke serious pathologic signs that can lead to death. MCs generate a number of preformed, de novo synthesized compounds and inflammatory cytokine/chemokine synthesis in response to the high-affinity (Kd=10–10 M) immuno...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Factors Influencing Oral Anticoagulation Prescription for Patients Presenting to Emergency Departments With Atrial Fibrillation and Flutter
Publication date: June 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 6Author(s): Robert J.H. Miller, Derek S. Chew, Saman Rezazadeh, Sheila Klassen, Payam Pournazari, Eddy Lang, F. Russell QuinnAbstractAtrial fibrillation and atrial flutter (AF/AFL) are associated with an increased risk of stroke and systemic embolism. However, many patients are not started on guideline-recommended oral anticoagulation (OAC). We determined factors associated with initiation of OAC in eligible patients presenting to emergency departments. This retrospective cohort included patients with electrocardiogram (ECG)-documented AF/A...
Source: Canadian Journal of Cardiology - July 5, 2018 Category: Cardiology Source Type: research

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study
Publication date: 30 June–6 July 2018 Source:The Lancet, Volume 391, Issue 10140 Author(s): Duminda N Wijeysundera, Rupert M Pearse, Mark A Shulman, Tom E F Abbott, Elizabeth Torres, Althea Ambosta, Bernard L Croal, John T Granton, Kevin E Thorpe, Michael P W Grocott, Catherine Farrington, Paul S Myles, Brian H Cuthbertson Background Functional capacity is an important component of risk assessment for major surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain accuracy. We did a study to compare preoperative subjective assessment with alternative markers of fitness (cardiopulmon...
Source: The Lancet - June 29, 2018 Category: General Medicine Source Type: research

Factors Influencing Oral Anticoagulation Prescription for Patients Presenting to Emergency Departments With Atrial Fibrillation and Flutter
Publication date: June 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 6 Author(s): Robert J.H. Miller, Derek S. Chew, Saman Rezazadeh, Sheila Klassen, Payam Pournazari, Eddy Lang, F. Russell Quinn Atrial fibrillation and atrial flutter (AF/AFL) are associated with an increased risk of stroke and systemic embolism. However, many patients are not started on guideline-recommended oral anticoagulation (OAC). We determined factors associated with initiation of OAC in eligible patients presenting to emergency departments. This retrospective cohort included patients with electrocardiogram (ECG)-documented AF/AFL pr...
Source: Canadian Journal of Cardiology - May 26, 2018 Category: Cardiology Source Type: research

Blood Pressure –Lowering Targets in Patients With Diabetes Mellitus
Publication date: May 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 5 Author(s): Alexander A. Leung, Raj S. Padwal Diabetes is a highly prevalent medical condition that commonly coexists with hypertension. The presence of diabetes and hypertension significantly increases the risk of adverse cardiovascular events. Although compelling evidence exists from randomized controlled trials demonstrating that blood pressure (BP) reduction effectively prevents cardiovascular complications, optimal BP targets remain uncertain and continue to be the subject of ongoing controversy. Until recently, most major clinical pr...
Source: Canadian Journal of Cardiology - May 4, 2018 Category: Cardiology Source Type: research

The Potential Effects of New Stent Platforms for Coronary Revascularization in Patients With Diabetes
Publication date: May 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 5 Author(s): Gustavo S. Guandalini, Sripal Bangalore Coronary artery disease in patients with diabetes mellitus (DM) is characterized by extensive atherosclerosis, longer lesions, and diffuse distal disease. Consequently, these patients have worse outcomes after coronary revascularization, regardless of the modality used. Traditionally, coronary artery bypass grafting (CABG) has been regarded as more effective than percutaneous coronary intervention (PCI) in patients with DM, likely because of more complete revascularization and protection ...
Source: Canadian Journal of Cardiology - May 4, 2018 Category: Cardiology Source Type: research