Article 1 of 3: Diabetes Quality Improvement (QI) Primer Series Beginning a Diabetes QI Project
Publication date: Available online 20 February 2019Source: Canadian Journal of DiabetesAuthor(s): Geetha Mukerji, Ilana Halperin, Phillip Segal, Lori Sutton, Rene Wong, Leigh Caplan, Dana Whitham, Julie A. GilmourAbstractThere is a large evidence-to-clinical practice gap in diabetes care. Application of quality improvement (QI) strategies can be used to improve gaps in care delivery. In this first of three articles in the diabetes QI primer series, we will introduce the steps required to plan a QI project, using a case example for improving foot screening among people with diabetes. We will review how to select an appropri...
Source: Canadian Journal of Diabetes - February 20, 2019 Category: Endocrinology Source Type: research

Cystic Fibrosis Related Diabetes Screening in Adults: A Gap Analysis & Evaluation of A1C Accuracy Response to the Letter to the Editor from Dr. Boudreau
Publication date: Available online 20 February 2019Source: Canadian Journal of DiabetesAuthor(s): Julie Gilmour (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - February 20, 2019 Category: Endocrinology Source Type: research

Self-monitoring of blood glucose: a complementary method beyond OGTT to identify hyperglycemia in pregnancy
Publication date: Available online 18 February 2019Source: Canadian Journal of DiabetesAuthor(s): Amélie Ardilouze, Patricia Bouchard, Marie-France Hivert, Catherine Simard, Catherine Allard, Marie-Pierre Garant, Julie Ménard, Annie Ouellet, Ghislaine Houde, Marie-Hélène Pesant, Jean-Patrice Baillargeon, Jean-Luc ArdilouzeAbstractObjectivesTo compare: 1) 75g-oral glucose tolerance test (OGTT) and self-monitoring of blood glucose (SMBG) in identifying gestational diabetes mellitus (GDM) and other hyperglycemic statuses in pregnant women, 2) pregnancy outcomes according to glycemic status, and 3) ...
Source: Canadian Journal of Diabetes - February 19, 2019 Category: Endocrinology Source Type: research

Enhancing Health Surveillance: Validation of a Novel Electronic Medical Record-Based Pediatric Type 1 and Type 2 Diabetes Mellitus Case Definition
ConclusionsWe describe a novel method to calculate the prevalence of pediatric DM in a primary care population. This case definition will improve pediatric DM surveillance, and enhance service planning and the development of strategies to support prevention and management. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - February 19, 2019 Category: Endocrinology Source Type: research

Evaluation of Healthy User Effects With Metformin and Other Oral Antihyperglycemia Medication Users in Adult Patients With Type 2 Diabetes
ConclusionsOur results suggest that metformin users are more likely to initiate preventive therapies and engage in other healthy behaviours. Failure to account for these behaviours may introduce healthy user bias into studies evaluating the effects of oral antihyperglycemic therapies.RésuméObjectifsLe biais lié aux utilisateurs sains selon lequel les patients ayant recours aux soins de santé sont plus susceptibles d'entreprendre des traitements préventifs et d'adopter des comportements sains liés au mode de vie est bien connu dans les études observationnelles, particuli&egra...
Source: Canadian Journal of Diabetes - February 17, 2019 Category: Endocrinology Source Type: research

Validation of a Stepwise Approach Using Glycated Hemoglobin Levels to Reduce the Number of Required Oral Glucose Tolerance Tests to Screen for Cystic Fibrosis–Related Diabetes in Adults
Publication date: Available online 23 November 2018Source: Canadian Journal of DiabetesAuthor(s): Valérie Boudreau, Quitterie Reynaud, Anne Bonhoure, Isabelle Durieu, Rémi Rabasa-Lhoret (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - February 1, 2019 Category: Endocrinology Source Type: research

Pharmacologic and non-pharmacologic therapies for type 2 diabetes on the gut microbiota
Publication date: Available online 31 January 2019Source: Canadian Journal of DiabetesAuthor(s): Robert CaesarAbstractThe gut microbiota is an important regulator of host metabolism. Metagenome analyses have demonstrated that the gut microbiota differs between type 2 diabetes patients and healthy subjects, and several studies have shown that impaired glucose metabolism is associated with decreased levels of butyrate-producing bacteria. Gut microbiota-produced metabolites such as short-chain fatty acids, amino acid-derivatives and secondary bile acids participate in metabolic and immunological processes and hence pose putat...
Source: Canadian Journal of Diabetes - February 1, 2019 Category: Endocrinology Source Type: research

Masthead
Publication date: February 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 1Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - January 30, 2019 Category: Endocrinology Source Type: research

Table of Contents
Publication date: February 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 1Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - January 30, 2019 Category: Endocrinology Source Type: research

Editorial Board
Publication date: February 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 1Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - January 30, 2019 Category: Endocrinology Source Type: research

What is the Real Usefulness of Glycated Hemoglobin Levels for Diabetes Screening in Patients With Cystic Fibrosis?
Publication date: February 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 1Author(s): Valérie Boudreau, Quitterie Reynaud, Rémi Rabasa-Lhoret (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - January 30, 2019 Category: Endocrinology Source Type: research

Risk Factors Of Recurrent Diabetic Ketoacidosis In Adults With Type 1 Diabetes
Publication date: Available online 28 January 2019Source: Canadian Journal of DiabetesAuthor(s): Sophie Del Degan, Frédérique Dubé, Claudia Gagnon, Geneviève BouletAbstractObjective: Identification of risk factors for recurrent diabetic ketoacidosis (DKA) among patients with type 1 diabetes (T1D) could help target those at high risk to implement preventative measures. The main objective of this study was to identify factors associated with recurrent DKA among Canadian adult patients with T1D.Research design and methodsThis is a retrospective cohort study of adult patients who had a diagnosis of ...
Source: Canadian Journal of Diabetes - January 29, 2019 Category: Endocrinology Source Type: research

Minimizing hyperglycaemia -induced vascular endothelial dysfunction by inhibiting endothelial sodium-glucose-cotransporter-2 and attenuating oxidative stress: Implications for treating individuals with type 2 diabetes
Publication date: Available online 23 January 2019Source: Canadian Journal of DiabetesAuthor(s): Vivek Krishna Pulakazhi Venu, Mahmoud El-Daly, Mahmoud Saifeddine, Simon A. Hirota, Hong Ding, Chris R. Triggle, Morley D. HollenbergAbstractThis overview deals with mechanisms whereby hyperglycaemia-induced oxidative stress compromises vascular endothelial function and provides a background for a recently published study illustrating the beneficial impact of endothelial sodium-glucose transporter-2 (SGLT2) inhibitors on attenuating hyperglycaemia-induced vascular dysfunction in vitro. The data provide new insight that can poss...
Source: Canadian Journal of Diabetes - January 24, 2019 Category: Endocrinology Source Type: research

Fast-acting insulin aspart and the need for new mealtime insulin analogues in adults with type 1 and type 2 diabetes: a Canadian perspective
Publication date: Available online 24 January 2019Source: Canadian Journal of DiabetesAuthor(s): Peter Senior, Irene HramiakAbstractLimiting postprandial glucose (PPG) excursions is an important aspect of overall glycemic control. Rapid-acting insulin analogues (RAIAs) aim to mimic the physiological action of endogenous insulin observed in individuals without diabetes and prevent excessive PPG excursions. However, many people with type 1 diabetes (T1D) and type 2 diabetes (T2D) treated with RAIAs do not achieve A1C targets, and there is an unmet need for further improvements in PPG control. Current RAIAs have a delayed ons...
Source: Canadian Journal of Diabetes - January 24, 2019 Category: Endocrinology Source Type: research

The Concept of Sleep Ability and its Effect on Diabetes Control in Adults With Type 2 Diabetes
ConclusionsThe significant elements of sleep ability represented the quality, quantity, maintenance, regularity and recognition of sleep, and each element made a large contribution to diabetes control. We conclude, therefore, that improving sleep ability may lead to good diabetes control.RésuméObjectifsPeu d'études publiées ont porté sur l'examen des effets des divers éléments du sommeil sur la maîtrise du diabète de type 2. La présente étude avait pour objectif l'élaboration d'un concept sur l'« aptitude au sommeil » et l'examen...
Source: Canadian Journal of Diabetes - January 23, 2019 Category: Endocrinology Source Type: research

Heat shock protein-70-mediated heat preconditioning attenuates hepatic carbohydrate and oxidative disturbances in rats with type-1 diabetes
Publication date: Available online 11 January 2019Source: Canadian Journal of DiabetesAuthor(s): Katerina Gerazova-Efremova, Suzana Dinevska – Kjovkarovska, Biljana MiovaAbstractHeat preconditioning (HP) and heat shock protein (HSP) synthesis have a significant cytoprotective effect against development of cellular injury caused by application of a subsequent stressor which was found to depend on the time period between the stressors. We aimed to determine the most efficient recovery time (6 and 24 hours) following heat stress exposure and prior application of diabetic streptozotocin (STZ) over moderation of carbohydr...
Source: Canadian Journal of Diabetes - January 11, 2019 Category: Endocrinology Source Type: research

Angiotensin receptor blockers and angiotensin-converting enzyme inhibitors for the treatment of hypertensive patients with type 2 diabetes mellitus
Publication date: Available online 11 January 2019Source: Canadian Journal of DiabetesAuthor(s): Tomoyuki Kawada (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - January 11, 2019 Category: Endocrinology Source Type: research

Associations of serum S100B and S100P with the presence and classification of diabetic peripheral neuropathy in adults with type 2 diabetes: a case-cohort study
This study was designed to investigate the potential associations of serum S100B and S100P with the presence and classification of diabetic peripheral neuropathy in adults with type 2 diabetes.MethodsIn a case-cohort setting, data of 44 diagnosed participants with diabetic peripheral neuropathy, 44 control participants with type 2 diabetes but free of peripheral neuropathy, and 87 healthy control individuals were collected and analyzed.ResultsSerum S100P concentrations were elevated in participants with diabetic peripheral neuropathy compared with their controls with T2D (median [IQR]: 2235 pg/ml [1497.5−2680] vs. 12...
Source: Canadian Journal of Diabetes - January 11, 2019 Category: Endocrinology Source Type: research

Implementation and Evaluation of a Diabetic Ketoacidosis Order Set in Pediatric Type 1 Diabetes at a Tertiary Care Hospital: A Quality Improvement Initiative
ConclusionsImplementation of a DKA order set in a tertiary hospital required identification of key stakeholders, formation of a multidisciplinary team, and the development of an evaluation process. There was an observed increase in physician order set uptake and DKA management practice improvements. Future goals involve expanding the implementation and evaluation process to provincial regional and remote centers and analyze the impact on resource utilization. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - December 27, 2018 Category: Endocrinology Source Type: research

Acute Management of Diabetic Ketoacidosis in Adults at 3 Teaching Hospitals in Canada: A Multicentre, Retrospective Cohort Study
ConclusionsThe acute management of DKA was generally aligned with clinical guidelines. Areas for improvement include preventing hypokalemia by proactively increasing potassium repletion, reducing initial insulin boluses, administering subcutaneous insulin before stopping intravenous insulin and administering sodium bicarbonate judiciously. Protocols and preprinted order sets may be helpful, especially in smaller centres.RésuméObjectifsL'acidocétose diabétique (ACD) est une complication à court terme fréquente du diabète sucré et est associée à des taux s...
Source: Canadian Journal of Diabetes - December 20, 2018 Category: Endocrinology Source Type: research

Erratum to “Cardiovascular Protection in People With Diabetes” Canadian Journal of Diabetes 2018;42(S1):S162-S169
Publication date: Available online 20 December 2018Source: Canadian Journal of DiabetesAuthor(s): James A. Stone, Robyn L. Houlden, Peter Lin, Jacob A. Udell, Subodh Verma (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - December 20, 2018 Category: Endocrinology Source Type: research

Erratum to “Nutrition Therapy” Canadian Journal of Diabetes 2018;42(S1):S64-S79
Publication date: Available online 20 December 2018Source: Canadian Journal of DiabetesAuthor(s): John L. Sievenpiper, Catherine B. Chan, Paula D. Dworatzek, Catherine Freeze, Sandra L. Williams (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - December 20, 2018 Category: Endocrinology Source Type: research

Duodental bypasses surgery improves type 2 diabetes in rat model through regulation of early glucose metabolism
This study aimed to measure the effects of duodenal-jejunal exclusion (DJE) on glycometabolism in non-obese type 2 diabetic rats, and to investigate the mechanisms. Goto–Kakizaki(GK) rats and Sprague–Dawley(SD) rats were divided into DJE operation groups and sham operation groups respectively. The glucose relative parameters were measured before and after operation. 8 weeks postoperation, the levels of the key regulators of intestinal gluconeogenesis and the crucial proteins of hepatic insulin signaling were evaluated. Postoperatively, the concentration of blood glucose declined and the insulin sensitivity was ...
Source: Canadian Journal of Diabetes - December 15, 2018 Category: Endocrinology Source Type: research

Glycated Hemoglobin Level Goal Achievement in Adults With Type 2 Diabetes in Canada: Still Room for Improvement
ConclusionsType 2 diabetes remains a health-care challenge in Canada and globally. Primary care physicians and specialists attributed patients' factors as principal obstacles to optimal diabetes management. However, physician-associated therapeutic inertia may also be an important barrier to unmet therapeutic goals.RésuméObjectifsDécrire les antécédents cliniques et la prise en charge des adultes atteints du diabète de type 2 qui n'avaient pas atteint leurs valeurs cibles d'hémoglobine glyquée (A1c) et déterminer les obstacles à l'atteinte des objectifs ...
Source: Canadian Journal of Diabetes - December 14, 2018 Category: Endocrinology Source Type: research

Evaluation of Healthy User Effect in Metformin and Other Oral Anti Hyperglycemic Medications Users among Adult Type 2 Diabetes Patients
ConclusionsOur results suggest that metformin users are more likely to initiate preventive therapies and engage in other healthy behaviors. Failure to account for these behaviours may introduce healthy user bias into studies evaluating the effect of oral antidiabetic therapies. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - December 14, 2018 Category: Endocrinology Source Type: research

Prevalence of Known Risk Factors for Type 2 Diabetes Mellitus in Multiethnic Urban Youth in Edmonton: Findings From the WHY ACT NOW Project
This study examined the risk factors for type 2 diabetes in multiethnic urban youth in Edmonton, Alberta.MethodsAn interviewer-administered questionnaire was developed based on CANRISK variables, such as age, gender, ethnicity, family history of diabetes, medical history of high blood sugar or high blood pressure, anthropometric measurements, physical activity and dietary intake. Between October 2013 and March 2014, data were collected from a convenience sample of 557 (328 girls and 229 boys) multiethnic youth 11 to 23 years of age in 12 institutions in Edmonton, such as public schools, after-school programs and colle...
Source: Canadian Journal of Diabetes - December 12, 2018 Category: Endocrinology Source Type: research

Elevated Carbohydrate Response Element-Binding Protein Beta (ChREBPβ) and Thioredoxin Interacting Protein (TXNIP) Levels in Human Adipocytes Differentiated in High Glucose Concentrations
ConclusionsHG-differentiated human adipocytes have distinct molecular differences and are insulin resistant. More studies are warranted to investigate potential mechanisms linking changes in ChREBPβ and TXNIP to insulin responsiveness.RésuméObjectifsLa coexistence de l’obésité et du diabète de type 2 est fréquente. Les répercussions de l’hyperglycémie sur le tissu adipeux présentent donc un intérêt. Bien que les études aient démontré que des concentrations élevées de glucose (GÉ) n’in...
Source: Canadian Journal of Diabetes - December 12, 2018 Category: Endocrinology Source Type: research

Risk factors for adverse outcomes in hyperglycemic patients presenting to the Emergency Department: a systematic review
ConclusionThis systematic review found twelve factors associated with adverse outcomes, and three factors associated with more favourable outcomes in patients presenting to the ED with hyperglycemia. These factors should be considered for easier identification of patients at higher risk for adverse outcomes to guide management and follow-up. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - December 7, 2018 Category: Endocrinology Source Type: research

The concept of “sleep ability” and its effect on diabetes control in adults with type 2 diabetes
ConclusionsThe significant elements of sleep ability represented the quality, quantity, maintenance, regularity, and recognition of sleep, and each element made a large contribution to diabetes control. We conclude, therefore, that improving sleep ability may lead to good diabetes control. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - December 6, 2018 Category: Endocrinology Source Type: research

Adjustment for Waist Circumference Reveals a U-Shaped Association Between Glycated Hemoglobin Levels and Body Mass Index in Young Adults
Publication date: Available online 21 September 2018Source: Canadian Journal of DiabetesAuthor(s): Ryoko Higuchi, Taizo Iwane, Kaname Suwa, Kei NakajimaAbstractObjectivesBody mass index (BMI) is used to assess adiposity worldwide. However, additional adjustment for waist circumference (WC), a surrogate marker of abdominal fat, may be capable of revealing a latent relationship between low body weight and glycated hemoglobin (A1C) concentration. Here, we investigated the relationship between A1C and BMI in young adults, adjusting for WC.MethodsWe reviewed A1C, BMI, WC and other clinical data in a cross-sectional study of 26,...
Source: Canadian Journal of Diabetes - November 30, 2018 Category: Endocrinology Source Type: research

In Vivo Type 2 Diabetes and Wound-Healing Effects of Antioxidant Gold Nanoparticles Synthesized Using the Insulin Plant Chamaecostus cuspidatus in Albino Rats
ConclusionsThe use of gold nanoparticles as antidiabetes materials has been achieved. Further studies are required before gold nanoparticle–based drugs are more widely used.RésuméContexteLes nanoparticules d'or sont connues pour leurs nombreuses applications dans les domaines de la thérapeutique et du diagnostic.MéthodesLe présent article porte principalement sur la méthode de synthèse verte des nanoparticules d'or à partir de la poudre d'extrait de feuilles de la plante d'insuline Chamaecostus cuspidatus et sur la caractérisation de la synthèse m&...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

The Health and Health Care of Adults With Type 1 And 2 Diabetes Across the Spectrum of Estimated Glomerular Filtration Rates
Publication date: Available online 21 June 2018Source: Canadian Journal of DiabetesAuthor(s): Kristin K. Clemens, Alexandra Ouédraogo, Danielle M. Nash, Amit X. Garg, Salimah Z. ShariffAbstractObjectivesLittle is known about the health and health-care patterns of patients with diabetes according to their estimated glomerular filtration rates, especially within a publicly funded health-care system.MethodsUsing linked health-care databases in Ontario, Canada, we performed a population-based study of adults 50 years of age and older (mean age, 68 years) with prevalent diabetes on January 1, 2014. We categorized patient...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Storytelling to Support Disease Self-Management by Adults With Type 2 Diabetes
ConclusionsInformal group storytelling enables patients to discuss, understand and give personal meaning to the information that was exchanged, and facilitates educators' better understanding of patients' concerns and gaps in knowledge and how-to strategies that can inform their practice. The group storytelling intervention is acceptable to patients and educators and can be delivered with high fidelity. Further research into effective patient recruitment methods and evaluation of the intervention's impact on diabetes self-management is required.RésuméObjectifsLe projet pilote visait à examiner l'accept...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Muscarinic Agonist Ameliorates Insulin Secretion in Wfs1-Deficient Mice
ConclusionsActivation of the muscarinic pathway to potentiate insulin secretion may present a target to manage diabetes resulting from Wfs1 deficiency.RésuméObjectifsTout comme les patients atteints du syndrome de Wolfram et les porteurs hétérozygotes de la mutation de la wolframine 1 (WFS1), les souris ayant une carence en WFS1 montrent une diminution de la tolérance au glucose et des concentrations plasmatiques plus faibles d'insuline. Il a déjà été démontré que les agonistes des récepteurs muscariniques de sous-type M3 (récepteurs...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Sleep Duration and Obesity in Children and Adolescents
Publication date: Available online 4 July 2018Source: Canadian Journal of DiabetesAuthor(s): Larine Sluggett, Shannon L. Wagner, R. Luke HarrisAbstractIncreased rates of obesity internationally have drawn significant attention. In particular, researchers and practitioners are seeking new information about risk factors for obesity that could be areas for preventive interventions. Given that obesity rates in children and adolescents are increasing worldwide, particular attention to child and adolescent obesity is needed. A large, and growing, body of research indicates that inadequate sleep duration is linked to obesity. The...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Evaluation of the rs3088442 G>A SLC22A3 Gene Polymorphism and the Role of microRNA 147 in Groups of Adult Pakistani Populations With Type 2 Diabetes in Response to Metformin
ConclusionsThese results suggested that the SLC22A3 rs3088442 at position 2282 A allele may confer metformin clinical responses in patients with type 2 diabetes in the Pakistani population. Overexpression of microRNA 147 is associated with a downward expression of the SLC22A3 gene in patients who have type 2 diabetes.RésuméObjectifsLe diabète de type 2 est une maladie à prédisposition génétique complexe à laquelle un grand nombre de polymorphismes génétiques peuvent participer à sa pathogenèse. Sur le plan pharmacologique, 9 classes de m&ea...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Intercellular Adhesion Molecule-1 Lys469Glu Polymorphism, Systemic Redox Homeostasis and Gestational Diabetes Mellitus in Pregnant Women
ConclusionsAlthough no significant difference was observed between genotypes, the oxidative damage observed in patients with GDM warrants earlier screening and management in the light of new evidence.RésuméObjectifsLa molécule d'adhérence intercellulaire 1 (ICAM-1, de l'anglais Intercellular adhesion molecule-1) joue un rôle important dans le fonctionnement endothélial. L'altération de l'état redox induit par l'hyperglycémie est l'une (1) des caractéristiques physiopathologiques bien connues du diabète sucré gestationnel (DSG), qui joue un r...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

A Comparison of Structured Education Programs for Pediatric Patients With Type 1 Diabetes: Multiple Daily Injection Therapy Delivered by Group Workshop vs. Self-Study Course
Publication date: Available online 9 August 2018Source: Canadian Journal of DiabetesAuthor(s): Karen Johnston, Gloria Wheeler, Elizabeth Rosolowsky (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Process Evaluation of the Diabetes Canada Guidelines Dissemination Strategy Using the Reach Effectiveness Adoption Implementation Maintenance (RE-AIM) Framework
ConclusionsOur interactive tools were repeatedly accessed, signifying their relevance to problems in clinical care. Our synthesized analyses indicate that the guidelines website is resource intensive, with a wide reach and the potential to change outcomes.RésuméObjectifsNotre objectif était de diffuser et de mettre en œuvre les lignes directrices de pratique clinique 2013 de l'Association canadienne du diabète, et d'évaluer les répercussions de la diffusion et de la mise en œuvre de la stratégie sur les résultats du processus (portée, adoption, mise...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Derivation and Validation of a Risk-Prediction Tool for Hypoglycemia in Hospitalized Adults With Diabetes: The Hypoglycemia During Hospitalization (HyDHo) Score
ConclusionsA parsimonious risk prediction model that uses 5 key clinical variables predicts hypoglycemia during hospitalization at the time of admission. More than one-quarter of patients at low risk for hypoglycemia had scores below the threshold. They could be identified at the time of admission by applying the HyDHo scoring system and may need less intensive glucose monitoring while in hospital.RésuméObjectifsNous avons cherché à établir le score Hypoglycemia During Hospitalization (HyDHo) pour prédire le risque d'hypoglycémie durant l'hospitalisation chez les patients di...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Development and Implementation of a Diabetic Ketoacidosis Protocol for Adults With Type 1 and Type 2 Diabetes at a Tertiary Care Multicampus Hospital
ConclusionsSuccessful implementation of a standardized preprinted protocol for DKA management significantly improved best practices for DKA management and was valued by treating clinicians.RésuméObjectifsL'acidocétose diabétique (ACD) est associée à une morbidité et à une mortalité importantes. L'utilisation de protocoles normalisés de prise en charge de l'ACD améliore les résultats cliniques et est recommandée par les lignes directrices de la pratique clinique de Diabète Canada. Les audits de soins de l'ACD de notre ét...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Combination Therapy With Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Older Patients With Type 2 Diabetes: A Real-World Evidence Study
Publication date: Available online 8 September 2018Source: Canadian Journal of DiabetesAuthor(s): Juana Carretero Gómez, José Carlos Arévalo Lorido, Ricardo Gómez Huelgas, Dolores García de Lucas, Lourdes Mateos Polo, José Manuel Varela Aguilar, Jose Miguel Seguí Ripoll, Javier Ena, Diabetes; Obesity; Nutrition Spanish Working GroupAbstractObjectivesScientific literature about the combination of glucagon-like peptide-1 receptor agonists (GLP-1ra) and sodium-glucose cotransporter 2 (SGLT2) inhibitors in older patients is scarce. We sought to assess the real-world efficacy and...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Patient Assessment of Family Function, Glycemic Control and Quality of Life in Adult Patients With Type 2 Diabetes and Incipient Complications
Publication date: Available online 17 September 2018Source: Canadian Journal of DiabetesAuthor(s): Birgitte B. Bennich, Lene Munch, Ingrid Egerod, Hanne Konradsen, Steen Ladelund, Filip K. Knop, Tina Vilsbøll, Michael Røder, Dorthe OvergaardAbstractObjectivesFamily affects the perception of diabetes self-management in patients with diabetes. Family-related questionnaires have been used to assess family function, but the Brief Family Assessment Measure (Brief FAM-III) has not been used previously in a diabetes population. We aimed to determine whether the family function is associated with glycated hemoglobin ...
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Tailoring Diabetes Education to Meet the Needs of Adults with Type 2 Diabetes and Mental Illness: Client and Healthcare Provider Perspectives From an Exploratory Pilot Study
ConclusionsOur study offers diabetes educators a strategy of how to apply Diabetes Canada's self-management education guidelines to the needs of people with mental illness, using suggestions from clients and clinicians. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Masthead
Publication date: December 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 6Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Table of Contents
Publication date: December 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 6Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Editorial Board
Publication date: December 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 6Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Diabetes and Dementia in the Elderly
Publication date: December 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 6Author(s): Graydon S. Meneilly (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Endorsement of Diabetes Canada's Alternative Approach to Diagnosis of Gestational Diabetes
Publication date: December 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 6Author(s): Jason M. Kong (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - November 29, 2018 Category: Endocrinology Source Type: research

Effects of pay-for-performance for primary care physicians on preventable diabetes-related hospitalization costs among adults in New Brunswick: a quasi-experimental evaluation
This study assesses the impacts of the P4P scheme on excess healthcare costs.MethodsWe use a quasi-experimental study design drawing on linked population-based administrative data sets of physician billings, hospital discharge abstracts, and provider and resident registrations. Prospective cohorts of patients with diabetes are identified through a validated algorithm tracing individuals’ interactions with the healthcare system. We apply propensity-score difference-in-differences estimation for effects of P4P on preventable diabetes-related hospitalization costs, by patient exposure to physician uptake of the incentiv...
Source: Canadian Journal of Diabetes - November 24, 2018 Category: Endocrinology Source Type: research