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World-Wide Efficacy of Bone Marrow Derived Mesenchymal Stromal Cells in Preclinical Ischemic Stroke Models: Systematic Review and Meta-Analysis
Conclusions: Our results show worldwide efficacy of BM-MSCs in improving functional outcomes in pre-clinical animal models of stroke and support testing these cells in clinical trials in various ranges of time windows using different delivery routes. The continued growing number of publications showing functional benefit of BM-MSCs are now adding limited value to an oversaturated literature spanning 18 years. Researchers should focus on identifying definitive mechanisms on how BM-MSCs lead to benefit in stroke models. Introduction Ischemic stroke is the 5th leading cause of death and the leading cause of long term di...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple sclerosis. ...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research

How can stroke care be improved for younger service users? A qualitative study on the unmet needs of younger adults in inpatient and outpatient stroke care in Australia.
CONCLUSIONS: This study provides new insights into the experience of inpatient and outpatient stroke care by younger stroke survivors and outlines possible improvements for clinical practice. Future research should evaluate the effect of targeted strategies to support younger adults after stroke. Implications for rehabilitation Post-stroke rehabilitation might be improved by providing more support for the non-physical effects of stroke (e.g., psycho-emotional support, cognitive rehabilitation). Younger stroke survivors may also benefit from a long-term community care plan and longer-term rehabilitation. Patient-centered re...
Source: Disability and Rehabilitation - January 7, 2019 Category: Rehabilitation Authors: Shipley J, Luker J, Thijs V, Bernhardt J Tags: Disabil Rehabil Source Type: research

Nutrition and hydration management among stroke patients in inpatient rehabilitation: a best practice implementation project
Conclusion: The current project successfully increased knowledge of nutrition and hydration management for stroke survivors and more closely aligned inpatient management with best practice guidelines to improve health outcomes. It highlighted areas of focus moving forward and has prompted ongoing work for sustaining evidence-based practice change.
Source: International Journal of Evidence-Based Healthcare - February 4, 2021 Category: Nursing Tags: IMPLEMENTATION PROJECTS Source Type: research

Meeting the need for post-stroke vision care in Australia: a scoping narrative review of current practice
CONCLUSION: Further research is needed into current Australian post-stroke vision care to accurately assess whether the needs of stroke survivors are being met. Available evidence indicates that in Australia, there is a requirement for well-defined protocols for vision screening, education, management, and referral of stroke survivors.Implications for RehabilitationPost-stroke vision care in Australia is unstandardised, which may cause inequities in vision care provision to Australian stroke survivors in different regions and/or care facilities.Education and training pertaining to stroke-related vision conditions for strok...
Source: Disability and Rehabilitation - May 25, 2023 Category: Rehabilitation Authors: Shanelle Sorbello Kathryn Rose Amanda French Fiona Rowe Sonia Lau Source Type: research

Understanding activity participation 3-months after stroke: a mixed methodology study.
CONCLUSION: Qualitative interviews extend our understanding of the process of returning to participation in life activities and occupations following stroke to reveal that it involves the stroke survivor in a dynamic adaptation process of synchronizing personal, environmental and temporal dimensions in their daily lives. IMPLICATIONS FOR REHABILITATION Rehabilitation professionals need to recognize the unique knowledge and ability stroke survivors have to manage their capacities, activities, occupations and environments. Client-centered practice involving true collaborative partnerships are needed to ensure stroke survivor...
Source: Disability and Rehabilitation - December 22, 2020 Category: Rehabilitation Authors: Tse T, Lentin P, Douglas J, Carey LM Tags: Disabil Rehabil Source Type: research

Counselling training for speech-language therapists working with people affected by post-stroke aphasia: a systematic review.
CONCLUSIONS: Research in counselling training for speech-language therapists working in post-stroke aphasia is limited, with a small number of primarily low-quality studies available. Training in generic counselling skills and brief psychological approaches with support from mental health professionals in the stroke workplace enabled speech-language therapists to feel knowledgeable, skilled and confident to address the psychological well-being of people affected by post-stroke aphasia. Evidence about the effectiveness of counselling training on speech-language therapists' confidence and competence in practice and on client...
Source: International Journal of Language and Communication Disorders - February 13, 2019 Category: Speech-Language Pathology Authors: Sekhon JK, Oates J, Kneebone I, Rose M Tags: Int J Lang Commun Disord Source Type: research

Stroke communication partner training: a national survey of 122 clinicians on current practice patterns and perceived implementation barriers and facilitators.
CONCLUSION & IMPLICATIONS: A significant evidence-practice gap exists. Research exploring the implementation of stroke CPT in healthcare settings, expanding evidence to support CPT for the range of post-stroke communication disorders, developing freely accessible step-by-step CPT programmes that consider restrictions in current practice and providing explicit instructions of CPT best practice are warranted. A supportive workplace culture and freely accessible formal training opportunities are also needed. PMID: 30151877 [PubMed - as supplied by publisher]
Source: International Journal of Language and Communication Disorders - August 27, 2018 Category: Speech-Language Pathology Authors: Chang HF, Power E, O'Halloran R, Foster A Tags: Int J Lang Commun Disord Source Type: research

Application of Machine Learning Techniques to Identify Data Reliability and Factors Affecting Outcome After Stroke Using Electronic Administrative Records
Conclusion: Electronic administrative records from this cohort produced reliable outcome prediction and identified clinically appropriate factors negatively impacting most outcome variables following hospital admission with stroke. This presents a means of future identification of modifiable factors associated with patient discharge destination. This may potentially aid in patient selection for certain interventions and aid in better patient and clinician education regarding expected discharge outcomes.
Source: Frontiers in Neurology - September 27, 2021 Category: Neurology Source Type: research

The Mobile Stroke Unit Nurse: An International Exploration of Their Scope of Practice, Education, and Training
CONCLUSION: We lack information on how many MSUs employ nurses, and the nurses' scope of practice, training, and expertise. Expert stroke nurse practitioners can safely perform many of the tasks undertaken by the onboard neurologist, making a nurse-led telemedicine model an effective and potentially cost-effective model that should be considered for all MSUs.
Source: Journal of Neuroscience Nursing - March 16, 2022 Category: Neuroscience Tags: Clinical Nursing Focus Source Type: research

Benefits of clinical facilitators on improving stroke care in acute hospitals: a new programme for Australia
ConclusionFixed‐term employment of Facilitators was effective in positively influencing stroke care in hospitals through a range of change management strategies where stroke‐specific expertise had been previously limited.
Source: Internal Medicine Journal - July 4, 2017 Category: Internal Medicine Authors: Tara Purvis, Karen Moss, Linda Francis, Karen Borschmann, Monique F. Kilkenny, Sonia Denisenko, Christopher F. Bladin, Dominique A. Cadilhac Tags: Original Article Source Type: research

Strength training to improve walking after stroke: how physiotherapist, patient and workplace factors influence exercise prescription.
Conclusions: Implementation of strength training to improve walking after stroke was diverse. Therapist-related barriers to the implementation of effective strength training programs highlight the need for improved knowledge, training and research engagement. Limited resourcing demonstrates the need for organizational prioritization of stroke education and skill development. Narrowing the evidence-practice gap remains a challenge. PMID: 33210574 [PubMed - as supplied by publisher]
Source: Physiotherapy Theory and Practice - November 19, 2020 Category: Physiotherapy Authors: Tole G, Raymond MJ, Williams G, Clark RA, Holland AE Tags: Physiother Theory Pract Source Type: research

Management of post-stroke fatigue: an Australian health professional survey
CONCLUSIONS: Few Australian health professionals formally assess post-stroke fatigue. Management is multidisciplinary and based on evidence from fatigue management in other conditions.Implications for rehabilitationMost health professionals are not routinely using formal assessment tools for fatigue, possibly due to a lack of consensus on best practice in research.Common strategies recommended by health professionals include energy optimisation strategies, education and exercise.Comprehensive guidelines for post-stroke fatigue management are yet to be established.Health professionals should assess post-stroke fatigue using...
Source: Disability and Rehabilitation - November 12, 2022 Category: Rehabilitation Authors: Stewart Blackwell Gary Crowfoot Julie Davey Avril Drummond Coralie English Margaret Galloway Gillian Mason Dawn Simpson Source Type: research

Evaluating remote facilitation intensity for multi-national translation of nurse-initiated stroke protocols (QASC Australasia): a protocol for a cluster randomised controlled trial
DISCUSSION: We will generate new evidence on the most effective facilitation intensity to support implementation of nurse-initiated stroke protocols nationwide, reducing geographical barriers for those in rural and remote areas.TRIAL REGISTRATION: ACTRN12622000028707. Registered 14 January, 2022.PMID:36703172 | DOI:10.1186/s13012-023-01260-9
Source: Rural Remote Health - January 26, 2023 Category: Rural Health Authors: O Fasugba S Dale E McInnes D A Cadilhac M Noetel K Coughlan B McElduff J Kim T Langley N W Cheung K Hill V Pollnow K Page E Sanjuan Menendez E Neal S Griffith L J Christie J Slark A Ranta C Levi J M Grimshaw S Middleton Source Type: research

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