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Specialty: Cardiology
Condition: Disability
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Total 417 results found since Jan 2013.
Stroke Doesn't Have to Lead to Death or Disability
(MedPage Today) -- Imagine having a severe, life-threatening stroke at 5 p.m., being rushed by ambulance to undergo minimally invasive surgery to remove the blood clot from your brain, then walking out of the hospital, symptom-free, the very next...
Source: MedPage Today Cardiovascular - September 15, 2023 Category: Cardiology Source Type: news
Global and national burden of atherosclerosis from 1990 to 2019: trend analysis based on the Global Burden of Disease Study 2019
CONCLUSIONS: From 1990 to 2019, there was an overall increasing trend in the global incidence of all three clinical manifestations of atherosclerosis. Between 1990 and 2019, both the mortality rate and DALYs for IHD and ischemic stroke declined across all age groups. Overall, the burden of atherosclerosis-related diseases has not significantly decreased and even shows signs of trending upward. These findings strongly suggest that despite some progress made, efforts to control atherosclerosis diseases globally need to be intensified.PMID:37677929 | DOI:10.1097/CM9.0000000000002839
Source: Atherosclerosis - September 7, 2023 Category: Cardiology Authors: Weihua Chen Zeya Li Yu Zhao Yitian Chen Rongchong Huang Source Type: research
Intracranial haemorrhage in acute myocardial infarction: A rare but dramatic complication
The shift from thrombolysis to primary percutaneous coronary intervention (PCI) and the use of multidrug antithrombotic therapy in the management of acute myocardial infarction (AMI) have led to both a substantial improvement in outcomes and a reduction in bleeding complications [1,2]. In particular, in AMI, the rate of haemorrhagic stroke, the most dreaded haemorrhagic complication, decreased by 50% from 1998 to 2008 [1]. Despite its low incidence, intracranial haemorrhage (ICH) is often devastating, being associated with severe disability and high mortality rates.
Source: International Journal of Cardiology - August 29, 2023 Category: Cardiology Authors: Filippo Trombara, Nicola Cosentino, Giancarlo Marenzi Tags: Editorial Source Type: research
Is Improving Educational Attainment Key to Reducing the Burden Because of Cardiovascular Diseases?
Cardiovascular diseases (CVDs) impose a substantial global public health burden, accounting for significant mortality and disability worldwide, particularly because of conditions like coronary heart disease and stroke. The economic consequences of CVDs, including healthcare expenses, decreased productivity, and diminished quality of life, further contribute to this burden. Lifestyle factors such as unhealthy diets, physical inactivity, tobacco use, and excessive alcohol consumption are closely associated with CVDs.
Source: The American Journal of Cardiology - August 1, 2023 Category: Cardiology Authors: Jari Antero Laukkanen, Setor Kwadzo Kunutsor Tags: Editorial Source Type: research
LP(a) levels related in severity and disability of ischemic stroke
Background and Aims: Lipoprotein(a) [Lp(a)] concentration is a causal risk factor for atherosclerotic cardiovascular disease.The association of Lp(a) and stroke-related neurologic deficits and stroke functional outcomes is unclear. The aim was to analyze whether high Lp(a) is associated with stroke severity and unfavorable functional outcomes.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: À. Pedragosa, A. Alija, M. Carmona, F. Ríos, C. Guerrero, R. Borrallo, M. Mauri Source Type: research
Profile of Nagasaki Islands Study (NaIS): A Population-Based Prospective Cohort Study on Multi-disease
In conclusion, the NaIS has been undertaken to reveal the influence of aging and risk factors of noncommunicable diseases and disabilities, with an aim to contribute towards better healthcare in the future.PMID:37517991 | DOI:10.2188/jea.JE20230079
Source: Atherosclerosis - July 30, 2023 Category: Cardiology Authors: Jun Miyata Hirotomo Yamanashi Shin-Ya Kawashiri Sakiko Soutome Kazuhiko Arima Mami Tamai Fumiaki Nonaka Yukiko Honda Masayasu Kitamura Koji Yoshida Yuji Shimizu Naomi Hayashida Shigeru Kawakami Noboru Takamura Takashi Sawase Atsutoshi Yoshimura Yasuhiro N Source Type: research
The Association between Ischemic Stroke Subtype and Stroke Severity: The Atherosclerosis Risk in Communities Study
DISCUSSION: Embolic stroke was associated with greater stroke severity at the time of the event, and higher risk of death versus thrombotic stroke, even after careful adjustment for patient-level differences.PMID:37414568 | DOI:10.1212/WNL.0000000000207535
Source: Atherosclerosis - July 6, 2023 Category: Cardiology Authors: Michelle C Johansen Jinyu Chen Andrea Lauren Christman Schneider Julia Carlson Taylor Haight Kamakshi Lakshminarayan Shalom Patole Rebecca F Gottesman Josef Coresh Silvia Koton Source Type: research
White Matter Cerebrovascular Reactivity: Effects of Microangiopathy and Proximal Occlusions on the Dynamic BOLD Response
CONCLUSION: Our results suggest additive effects of microvascular and macrovascular disease upon white matter CVR, but with greater overall effects relating to macrovascular SOD than to apparent microangiopathy. Dynamic ACZ-BOLD presents a promising path towards a quantitative stroke risk imaging biomarker.BACKGROUND: Cerebral white matter (WM) microangiopathy manifests as sporadic or sometimes confluent high intensity lesions in MR imaging with T2-weighting, and bears known associations with stroke, cognitive disability, depression and other neurological disorders 1-5 . Deep white matter is particularly susceptible to isc...
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: J Michael Gee Xiuyuan Wang Siddhant Dogra Jelle Veraart Koto Ishida Seena Dehkharghani Source Type: research
Pericyte-Mediated Molecular Mechanisms Underlying Tissue Repair and Functional Recovery after Ischemic Stroke
J Atheroscler Thromb. 2023 Jun 30. doi: 10.5551/jat.RV22007. Online ahead of print.ABSTRACTThere are still many patients suffering from ischemic stroke and related disabilities worldwide. To develop a treatment that promotes functional recovery after acute ischemic stroke, we need to elucidate endogenous tissue repair mechanisms. The concept of a neurovascular unit (NVU) indicates the importance of a complex orchestration of cell-cell interactions and their microenvironment in the physiology and pathophysiology of various central nervous system diseases, particularly ischemic stroke. In this concept, microvascular pericyte...
Source: Journal of Atherosclerosis and Thrombosis - July 2, 2023 Category: Cardiology Authors: Kuniyuki Nakamura Tetsuro Ago Source Type: research
Risk Factors and Immunoinflammatory Mechanisms Leading to Atherosclerosis: Focus on the Role of Oral Microbiota Dysbiosis
Microorganisms. 2023 Jun 1;11(6):1479. doi: 10.3390/microorganisms11061479.ABSTRACTCardiovascular diseases (CVD), including myocardial infarction and stroke, are currently the leading cause of morbidity, disability and mortality worldwide. Recently, researchers have focused their attention on the alterations of the gut and oral microbiota, investigating the possible role of their dysbiosis in the pathogenesis and/or progression of CVD. In this regard, it has been shown that endothelial dysfunction, a major feature of CVD, can also be induced by chronic periodontal infection, due to a systemic pro-inflammatory condition, as...
Source: Atherosclerosis - June 28, 2023 Category: Cardiology Authors: Riccardo Mattia Ricciardi Alessia Cipollone Damiano D'Ardes Davide Di Giacomo Pamela Pignatelli Francesco Cipollone Maria Cristina Curia Paolo Magni Marco Bucci Source Type: research
Atrial Cardiopathy: Redefining Stroke Risk Beyond Atrial Fibrillation
Atrial fibrillation (AF) and ischemic stroke are dual epidemics in society, both associated with poor clinical outcomes, patient disability, and significant healthcare expenditure. The conditions are interrelated and share complex causal pathways. Risk stratification algorithms such as the CHADS2 and CHA2DS2-VASc score offer predictive value in stroke and systemic embolism risk in the AF population, however, have limitations. Recent evidence suggests that an intrinsically prothrombotic atrial substrate may precede and promote AF and lead to thromboembolic events independent of the arrhythmia, allowing for a window of inter...
Source: The American Journal of Cardiology - June 28, 2023 Category: Cardiology Authors: Jessica Chu Zhang, Aditya Bhat Source Type: research
Dual Versus Mono Antiplatelet Therapy in Patients with Acute Mild-to-Moderate Stroke: A Multicentre Perspective Cohort Study
ConclusionAspirin plus clopidogrel was associated with a reduction in the incidence of disability attributed to index stroke. There was no statistically significant difference in the incidence of moderate to severe bleeding complications between the two antiplatelet drug regimens.Trial Registration NumberChiCTR1900025214.
Source: Cardiovascular Drugs and Therapy - June 13, 2023 Category: Cardiology Source Type: research
