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Total 55 results found since Jan 2013.

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II
Conclusion: In ischemic stroke or TIA patients with platelet count within normal range, platelet count may be a qualified predictor for long-term recurrent stroke, mortality, and poor functional outcome. Introduction Platelets exert a critical role in the pathogenesis of atherosclerotic complications of cardio-cerebrovascular disease, contributing to thrombus formation, and embolism (1, 2). Previous literature reported that platelets of various size and density are produced by megakaryocytes of different size and stages of maturation in different clinical conditions, suggesting various platelet patterns in differen...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study
Conclusions: Pre-injury psychiatric and pre-injury headache/migraine symptoms are risk factors for worse functional and post-concussive outcomes at 3- and 6-months post-mTBI. mTBI patients presenting to acute care should be evaluated for psychiatric and headache/migraine history, with lower thresholds for providing TBI education/resources, surveillance, and follow-up/referrals. Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT01565551. Introduction Traumatic brain injury (TBI) remains a significant cause of morbidity and mortality worldwide. In 2013 ~2.8 million TBI cases were recorded an...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Depressive symptoms across the age span: findings from an integrated epilepsy self-management clinical studies dataset.
Epilepsy has been reported by the CDC to have a prevalence of 1.2% in the United States, which accounts for roughly 3.4 million adults in 2015. Nearly 1 million of those adults are aged 55 or older.1 Epilepsy is more likely to develop in older adults because risk factors for epilepsy are more common as people age including stroke/cardiovascular disease, neurodegenerative disorders, brain tumor and long-term sequelae of alcohol abuse.2 As our population ages, there will be even more older people with epilepsy.
Source: The American Journal of Geriatric Psychiatry - February 28, 2019 Category: Geriatrics Authors: Zaira Khalid, Hasina Momotaz, Kristen Cassidy, Naomi Chaytor, Robert Fraser, Mary Janevic, Barbara Jobst, Erica Johnson, Peter Scal, Tanya Spruill, Martha Sajatovic Tags: Poster Number: EI - 9 Source Type: research

Superbugs, Anti-Vaxxers Make WHO ’ s List Of 10 Global Health Threats
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 21, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Local TV Source Type: news

Non-Invasive In Vivo MRI Method to Image Salient Features of Axons and Nerves
The invention from Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) provides a non-invasive, painless means for measuring microanatomical features of Nerve and Axon Diameter Distribution (ADD) to image the Central and Peripheral Nervous Systems (CNS and PNS). ADD is altered in abnormal development (e.g., autism), in neurodegenerative processes (e.g., aging, alcoholism, Alzheimer ’s disease) and diseases such as ALS (Lou Gehrig’s disease). U.S. patent 7,643,863, related to this invention, consists of a novel diffusion Magnetic Resonance Imaging (MRI) experiment and modeling framew...
Source: NIH OTT Licensing Opportunities - November 14, 2018 Category: Research Authors: ajoyprabhu3 Source Type: research

An Egg A Day Might Reduce Your Risk Of Heart Disease, Study Says
In this study however, they didn’t assess the risk of developing diabetes, which may be because diabetes is a newer disease in the Chinese population and there is not good documentation of who has it,” Richard said. Still, she noted, “this will be very important data for helping develop dietary prevention guidelines in China.” Cardiovascular disease, which takes the lives of 17.7 million people every year, is the leading cause of death and disability worldwide, according to the World Health Organization. Cardiovascular disease causes nearly a third — 31% — of all global deaths each year....
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Eggs Heart Disease Local TV Source Type: news

A case of refractary epilepsy and related pain due to dysmenorrhea solved with loading dose of lacosamide: clinical and neurophysiological correlates.
Abstract  In most cases, the etiology of epilepsy is unknown, although some individuals may develop epilepsy as a result of certain brain injuries, following a stroke, a brain tumor or because of drugs and alcohol. Even some rare genetic mutations may be related to the onset of the condition. Seizures are the result of excessive and abnormal activity of neurons in the cerebral cortex. In this case report we show a clinical case of refractory epilepsy due to pain related to uncontrolled dysmenorrhea. The patient, 43 yrs old, had a history of epilepsy of 20 years and ovarian cancer. She was treated with lamotrigine...
Source: Acta Bio-Medica : Atenei Parmensis - October 23, 2017 Category: General Medicine Authors: Marchitto N, Ceratti U, Dalmaso S, Raimondi G Tags: Acta Biomed Source Type: research

The Medical Emergency Of Otto Warmbier
All that the doctors who treated Cincinnati, Ohio resident Otto Warmbier knew is what they had seen or maybe read in the news. They knew he had just been released on June 13 from imprisonment in North Korea where he had been held by for more than 17 months. He had been sentenced in March 2016 to 15 years of hard labor for allegedly removing a propaganda poster from a wall at a Pyongyang hotel where he had been staying. The University of Virginia honors student had been visiting the authoritarian state during a five-day trip with a group called Young Pioneer Tours, which is a group out of China – an important note. Ot...
Source: Healthy Living - The Huffington Post - June 22, 2017 Category: Consumer Health News Source Type: news

Survival in Out-of-hospital Rapid Sequence Intubation of Non-Traumatic Brain Pathologies.
CONCLUSIONS: Non-traumatic brain pathologies are seven times more prevalent than traumatic brain injuries in patients that underwent out-of-hospital RSI in Victoria, Australia. Since the mechanisms through which RSI impacts mortality might differ between traumatic brain injuries and NTBP, and given that NTBP is very prevalent, it follows that the use of RSI in NTBP could be unsupported. PMID: 28622071 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - June 19, 2017 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Risk of aspirin-related bleeding is higher in the over-75s
Conclusion This valuable cohort study helps to quantify the extent of bleeding risk in people taking aspirin for secondary prevention of cardiovascular disease. Aspirin is well known to carry bleeding risk – particularly in older adults – but this study suggests the risk may be higher than previously thought. The researchers say that for adults under the age of 75, the annual bleeding risk at around 1% is similar to that suggested by previous trials, as is the ratio of bleeds to the number of cardiovascular events. However, this risk increases for older adults, especially for major bleeds of the stomach and upper diges...
Source: NHS News Feed - June 14, 2017 Category: Consumer Health News Tags: Medication Older people Source Type: news

Two older drugs could be 'repurposed' to fight dementia
Conclusion This early stage experimental research has demonstrated a beneficial neurological effect of trazodone and dibenzoylmethane on mice with diseases mimicking neurodegenerative diseases. It is important to acknowledge that this is animal research and therefore the drugs might not have the same effect when they are trialled on humans. That being said, trazodone is already an approved drug for depression and sleep problems and has therefore already passed safety tests. If the mechanisms of neurodegeneration in humans and mice are similar, it is possible trazodone could be used in the future in treating Alzheimer's and...
Source: NHS News Feed - April 20, 2017 Category: Consumer Health News Tags: Older people Neurology Medication Source Type: news

Man-in-the-barrel syndrome with Delayed Diffusion-weighted MRI Findings (P3.072)
Conclusions:DWI has a high degree of sensitivity and specificity. Nevertheless, false negative results often occur because of small infarct size, early imaging, and brainstem locations. The rate of false negative results with DWI has been estimated to be 17%. We argue it may be advisable to repeat MRI in certain cases were stroke is highly suspected up to 72 hours post symptoms. Often false negative DWI occur in posterior circulation strokes making our case unique, given it is in the anterior circulation. One possible explanation for this, is differences in cerebral reserve between a young patient versus an older patient d...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Magun, R., Ching, M., Sawyer, R., Mowla, A. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Moderate drinking may reduce heart disease risk
Conclusion This study paints a more complicated picture than the "Pint a day keeps the doctor away" story proffered by The Sun. It seems to confirm the findings of other studies, which have shown that non-drinkers tend to have a higher risk of cardiovascular diseases than people who drink moderately. It suggests that some cardiovascular diseases (mainly those directly affecting the heart) seem to have a stronger link to a possible protective effect from alcohol than other vascular diseases, such as mini-strokes and bleeding in the brain. However, this can't be concluded with certainty due to the study design. We ...
Source: NHS News Feed - March 23, 2017 Category: Consumer Health News Tags: Heart/lungs Food/diet Lifestyle/exercise Source Type: news

Substance found in red wine 'helps fight ageing'
Conclusion Resveratrol has been of interest to anti-ageing scientists for many years and researchers have previously shown it may be linked to a slowing of the decline in thinking and movement, at least in rodents. This study suggests a possible way this might happen. But the results don't tell us anything about what happens in humans. They suggest this substance may be useful for further research in humans at some point. They certainly don't provide a reason to drink gallons of red wine, in the hope of seeing an anti-ageing effect. Drinking too much alcohol is a sure-fire way to speed up deterioration of thinking skills,...
Source: NHS News Feed - March 8, 2017 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise Neurology Source Type: news

Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study
Conclusions: TL and CRP levels may help predict the impact of BC exposure on cognitive function in older men. Citation: Colicino E, Wilson A, Frisardi MC, Prada D, Power MC, Hoxha M, Dioni L, Spiro A III, Vokonas PS, Weisskopf MG, Schwartz JD, Baccarelli AA. 2017. Telomere length, long-term black carbon exposure, and cognitive function in a cohort of older men: the VA Normative Aging Study. Environ Health Perspect 125:76–81; http://dx.doi.org/10.1289/EHP241 Address correspondence to E. Colicino, Department of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave., Building 1, Room G03, Bos...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research