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Condition: Thrombosis
Procedure: Percutaneous Coronary Intervention
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Total 862 results found since Jan 2013.
Outcomes after thrombus aspiration for ST elevation myocardial infarction: 1-year follow-up of the prospective randomised TOTAL trial
Publication date: Available online 22 October 2015 Source:The Lancet Author(s): Sanjit S Jolly, John A Cairns, Salim Yusuf, Michael J Rokoss, Peggy Gao, Brandi Meeks, Sasko Kedev, Goran Stankovic, Raul Moreno, Anthony Gershlick, Saqib Chowdhary, Shahar Lavi, Kari Niemela, Ivo Bernat, Warren J Cantor, Asim N Cheema, Philippe Gabriel Steg, Robert C Welsh, Tej Sheth, Olivier F Bertrand, Alvaro Avezum, Ravinay Bhindi, Madhu K Natarajan, David Horak, Raymond C M Leung, Saleem Kassam, Sunil V Rao, Magdi El-Omar, Shamir R Mehta, James L Velianou, Samir Pancholy, Vladimír Džavík Background Two ...
Source: The Lancet - October 23, 2015 Category: Journals (General) Source Type: research
Comparison between the Outcomes of Intracoronary and Intravenous Administration of Eptifibatide during Primary Percutaneous Coronary Intervention in Patients with Acute ST-Elevation Myocardial Infarction.
CONCLUSIONS: IC administration of eptifibatide during PPCI in patients with STEMI in comparison with IV administration of eptifibatide is associated with significantly better coronary reperfusion and improved clinical outcomes (IRCT2012090510751N1).
PMID: 26632161 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - December 5, 2015 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Meta‐analysis of randomized controlled trials comparing percutaneous coronary intervention with aspiration thrombectomy Vs. Conventional percutaneous coronary intervention during ST‐segment elevation myocardial infarction
ConclusionsUsing the totality of evidence available through 2015, this meta‐analysis failed to show that the routine use of aspiration thrombectomy in patients with ST‐elevation myocardial infarction significantly reduces all‐cause mortality, MACE, recurrent MI, TVR, or stent thrombosis. The role of aspiration thrombectomy in selected patients with angiographic evidence of large thrombus burden requires further clinical investigation. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - December 23, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Abel Casso Dominguez, John A. Bittl, Georges El‐Hayek, Elizabeth Contreras, Jacqueline E. Tamis‐Holland Tags: Coronary Artery Disease Source Type: research
The OPTImal duration of Dual Anti Platelet Therapy in patients receiving percutaneous coronary intervention with drug-eluting stents.
CONCLUSIONS: There was no difference in efficacy outcomes between short-term and long-term DAPT following DES, even among high-risk patients.However, longer duration of DAPT was found to be associated with increased risk of major bleeding.
PMID: 26711462 [PubMed - as supplied by publisher]
Source: Cardiology Journal - December 29, 2015 Category: Cardiology Authors: Sheyin O, Perez X, Pierre-Louis B, Kurian D Tags: Cardiol J Source Type: research
Rheolytic Thrombectomy for Acute Myocardial Infarction Complicated by Cardiogenic Shock.
CONCLUSION: RT reduces 2-year MACE rate in patients with large thrombus burden and AMI complicated by CS.
PMID: 27187985 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - May 18, 2016 Category: Cardiology Tags: J Invasive Cardiol Source Type: research
P2Y12 receptor antagonists: which one to choose? A systematic review and meta-analysis.
Conclusion: Newer P2Y12 receptor antagonists are associated with better cardiovascular outcomes in patients with ACS and/or undergoing PCI. Prasugrel use resulted in higher major bleeding rates and no overall mortality benefit compared with clopidogrel.
PMID: 27290917 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - June 7, 2016 Category: Drugs & Pharmacology Authors: Briasoulis A, Telila T, Palla M, Siasos G, Tousoulis D Tags: Curr Pharm Des Source Type: research
Effectiveness and Safety of Bivalirudin During Percutaneous Coronary Intervention in Acute Coronary Syndrome in the Real World: CARTAGOMAX Study
Abstract: The CARTAGOMAX study assessed the safety and efficacy of bivalirudin during real-world cardiac intervention. This was a single-center prospective study. Patients with acute coronary syndrome undergoing percutaneous coronary intervention were anticoagulated with bivalirudin alone or unfractionated heparin plus a glycoprotein IIb/IIIa inhibitor. Propensity score matching was performed to control for baseline imbalances and yielded 1168 patients. There was lower incidence of the composite outcome of death from any cause or major bleeding at 30 days (P = 0.005), 6 months (P = 0.005), and 12 months (P = 0.001) of foll...
Source: Journal of Cardiovascular Pharmacology - September 1, 2016 Category: Cardiology Tags: Original Article Source Type: research
Impact of Impaired Renal Function in Patients With Severely Calcified Coronary Lesions Treated With Orbital Atherectomy.
CONCLUSION: Despite higher-risk baseline characteristics, patients with CKD had no significant differences in MACCE. Orbital atherectomy represents a reasonable treatment strategy for the treatment of severe CAC in patients with CKD. A prospective randomized trial with long-term follow-up is needed to identify the optimal treatment for these patients.
PMID: 28089999 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - January 18, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Manual thrombectomy efficiency in relationship to the area at risk in patients with myocardial infarction with TIMI 0 ‐1 coronary flow: Insights from an all comers registry
ConclusionIn comparison with the group where MT was inefficient, efficient MT may modestly reduce final infarct size without a significant clinical benefit. In comparison with PCI‐only, no difference was found regarding stroke. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - February 12, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Andr é Luz, Inês Silveira, Bruno Brochado, Patrícia Rodrigues, Maria João Sousa, Raquel Santos, Maria Trêpa, Mário Santos, João Silveira, Severo Torres, Adelino F. Leite‐Moreira, Henrique Carvalho Tags: Coronary Artery Disease Source Type: research
Myocardial Wall Rupture Following tPA Administration: A Case Report and Review of the Literature (P3.270)
Conclusions:Although the frequency of pericarditis, mural hemorrhage and subsequent myocardial rupture after MI is declining following PCI, clinicians should be mindful of this potential complication in tPA treated patients with recent MI. Further, cardiac wall rupture should be considered in patients who develop acute hypotension and bradycardia following tPA administration. The current literature is limited and insufficient to provide generalizable guidance on managing AIS patients with recent MI.Disclosure: Dr. Neu has nothing to disclose. Dr. Albright has nothing to disclose. Dr. Lyerly has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Neu, M., Albright, K., Lyerly, M. Tags: Cerebrovascular Disease Case Reports II Source Type: research
Combined Use of Neutrophil to Lymphocyte Ratio and C-Reactive Protein Level to Predict Clinical Outcomes in Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention.
CONCLUSION: Elevated levels of both NLR and CRP are associated with increased risk of long-term mortality in AMI patients who have undergone PCI.
PMID: 28567089 [PubMed - in process]
Source: Korean Circulation Journal - June 3, 2017 Category: Cardiology Tags: Korean Circ J Source Type: research
Head ‐to‐head comparison of prasugrel versus ticagrelor in patients undergoing percutaneous coronary intervention: A meta‐analysis of randomized controlled trials
ConclusionsAlthough the efficacy was similar between prasugrel and ticagrelor, prasugrel may be associated with a lower risk of bleeding compared with ticagrelor during short‐ to mid‐term follow‐up period after PCI. Further studies are warranted in a larger patient population during longer‐term follow up to validate these findings.
Source: Journal of Interventional Cardiology - August 1, 2017 Category: Cardiology Authors: Ryota Sakurai, Ivana Burazor, Heidi N. Bonneau, Hideaki Kaneda Tags: ORIGINAL INVESTIGATION Source Type: research
Platelet reactivity-adjusted antiplatelet therapy in patients with percutaneous coronary intervention: a meta-analysis of randomized controlled trials.
Authors: Xing Z, Tang L, Zhu Z, Huang J, Peng X, Hu X
Abstract
Numerous number of evidences show that high on-treatment platelet reactivity is a well-known risk factor for adverse events in patients after percutaneous coronary intervention (PCI). Controversial situations still exist regarding the effectiveness of tailoring antiplatelet therapy according to platelet function monitoring. The PubMed, Embase, and Cochrane Central databases were searched for randomized trials comparing platelet reactivity-adjusted antiplatelet therapy with conventional antiplatelet therapy in patients undergoing PCI. The primary end poi...
Source: Platelets - September 14, 2017 Category: Hematology Tags: Platelets Source Type: research
The safety and efficacy of oral anticoagulants with dual versus single antiplatelet therapy in patients after percutaneous coronary intervention: A meta-analysis
Conclusion: In patients on OAC undergoing PCI with stent implantation, compared with DT, TT shows equal effectiveness in terms of MACE, stroke, all-cause mortality, and stent thrombosis and lower risks of myocardial infarction and major bleeding. However, similar efficacy and safety outcomes were observed between the TT group and the OAC along with clopidogrel group.
Source: Medicine - September 1, 2017 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Outcomes of Patients With a History of Coronary Artery Bypass Grafting Who Underwent Orbital Atherectomy for Severe Coronary Artery Calcification.
CONCLUSION: Despite a higher-risk baseline profile, patients with a history of CABG had similar angiographic and clinical outcomes compared with patients who had no previous history of CABG. Further studies are needed to clarify the role of orbital atherectomy in these patients.
PMID: 28974662 [PubMed - in process]
Source: The Journal of Invasive Cardiology - October 6, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research
