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Condition: Thrombosis
Nutrition: Chloride

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Total 40 results found since Jan 2013.

Facilitation of ultrasonic microvesicles on homing and molecular mechanism of bone marrow mesenchymal stem cells in cerebral infarction patients.
CONCLUSIONS: Ultrasound microvesicle facilitated homing of BMSCs in cerebral infarction, and improved infarction disease via up-regulating VEGF expression, inhibiting NF-κB expression, and modulating apoptosis. PMID: 28975970 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - October 5, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Role of the chemokine receptors CCR2 and CX3CR1 in an experimental model of thrombotic stroke
This study underlines a key role of CCR2- and CX3CR1-expressing immune cells in the neuropathology associated with ischemic injuries.
Source: Brain, Behavior, and Immunity - July 5, 2018 Category: Neurology Source Type: research

KLF11 (Kru üppel-Like Factor 11) Inhibits Arterial Thrombosis via Suppression of Tissue Factor in the Vascular Wall.
Conclusions- Our data demonstrate that KLF11 is a novel transcriptional suppressor of F3 in vascular smooth muscle cells, constituting a potential molecular target for inhibition of arterial thrombosis. PMID: 30602303 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - January 3, 2019 Category: Cardiology Authors: Liang W, Fan Y, Lu H, Chang Z, Hu W, Sun J, Wang H, Zhu T, Wang J, Adili R, Garcia-Barrio MT, Holinstat M, Eitzman D, Zhang J, Chen YE Tags: Arterioscler Thromb Vasc Biol Source Type: research

Targeting Myeloperoxidase (MPO) Mediated Oxidative Stress and Inflammation for Reducing Brain Ischemia Injury: Potential Application of Natural Compounds
This article discusses the important roles of MPO in mediating oxidative stress and neuroinflammation during cerebral ischemia-reperfusion injury and reviews the current understanding of the underlying mechanisms. Furthermore, we summarize the active compounds from medicinal herbs with potential as MPO inhibitors for anti-oxidative stress and anti-inflammation to attenuate cerebral ischemia-reperfusion injury, and as adjunct therapeutic agents for extending the window of thrombolytic treatment. We highlight that targeting MPO could be a promising strategy for alleviating ischemic brain injury, which merits further translational study.
Source: Frontiers in Physiology - May 18, 2020 Category: Physiology Source Type: research

Comparison of Serum Selenium Levels Between Patients with Newly Diagnosed Atrial Fibrillation and Normal Controls
Biol Trace Elem Res. 2022 May 9. doi: 10.1007/s12011-022-03281-9. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the most common sustained dysrhythmia in the elderly population. It is estimated to affect more than 30 million people worldwide. AF occurs when abnormal electrical impulses start to activate in the atria and override the heart's natural pacemaker, which can no longer control the heart's rhythm. Since atrial contractility is impaired in AF, blood flow in the atria becomes stasis over time and causes thrombus formation. This thrombus causes the risk of embolism and causes complications such as stroke. ...
Source: Biological Trace Element Research - May 8, 2022 Category: Biology Authors: Isa Ardahanli Halil Ibrahim Ozkan Source Type: research

The combination of Astragalus membranaceus and ligustrazine mitigates cerebral ischemia ‐reperfusion injury via regulating NR2B‐ERK/CREB signaling
ConclusionsThe overall results thus suggest that the Ast+Lig combination conferred neuroprotective properties against cerebral I/R injury via regulation of the NR2B-ERK/CREB signaling pathway.
Source: Brain and Behavior - December 31, 2022 Category: Neurology Authors: Xialing Tang, Shanshan Xie, Huajun Wang, Yingbin Li, Zhiyu Lai, Shuangxi Sun, Ruanhuan Pan, Yan Huang, Jun Cai Tags: ORIGINAL ARTICLE Source Type: research

High Contrast Detection of Carotid Neothrombus with Strong Near-Infrared Absorption Selenium Nanosphere Enhanced Photoacoustic Imaging
CONCLUSION: The superior PA signal of Se@PPy nanomaterials can identify the extent of atherosclerotic carotid lesions, demonstrating the feasibility of PA imaging technology in diagnosing carotid thrombosis lesion formation. This study demonstrates nanocomposites and PA techniques for imaging and diagnosing carotid thrombosis in vivo.PMID:37520300 | PMC:PMC10377622 | DOI:10.2147/IJN.S404743
Source: Atherosclerosis - July 31, 2023 Category: Cardiology Authors: Fengbing He Wenzhong Hou Yintao Lan Weijian Gao Mengyu Zhou Jinghang Li Shutong Liu Bin Yang Jian Zhang Source Type: research