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Source: Stroke
Condition: Thrombosis

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Total 230 results found since Jan 2013.

Time-Dependent Thrombus Resolution After Tissue-Type Plasminogen Activator in Patients With Stroke and Mice Clinical Sciences
Conclusions— Early administration of tPA after stroke onset is associated with better thrombus resolution.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Kim, Y. D., Nam, H. S., Kim, S. H., Kim, E. Y., Song, D., Kwon, I., Yang, S.-H., Lee, K., Yoo, J., Lee, H. S., Heo, J. H. Tags: Arterial thrombosis, Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Prophylactic Edaravone Prevents Transient Hypoxic-Ischemic Brain Injury: Implications for Perioperative Neuroprotection Basic Sciences
Conclusions— Acute application of Edaravone may be a useful strategy to prevent postsurgery stroke and cognitive impairment, especially in patients with severe carotid stenosis.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Sun, Y.-Y., Li, Y., Wali, B., Li, Y., Lee, J., Heinmiller, A., Abe, K., Stein, D. G., Mao, H., Sayeed, I., Kuan, C.-Y. Tags: Animal models of human disease, Other Stroke Treatment - Medical, Coagulation and fibronolysis Basic Sciences Source Type: research

Intracranial Dural Arteriovenous Fistulae: Clinical Presentation and Management Strategies Topical Reviews
Source: Stroke - June 22, 2015 Category: Neurology Authors: Miller, T. R., Gandhi, D. Tags: CT and MRI, Acute Cerebral Hemorrhage, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Cerebral Venous Thrombosis, Angiography, Intracerebral Hemorrhage, Aneurysm, AVM, hematoma Topical Reviews Source Type: research

Day-by-Day Blood Pressure Variability and Functional Outcome After Acute Ischemic Stroke: Fukuoka Stroke Registry Clinical Sciences
Conclusions— These data suggest that intraindividual day-by-day BP variability during the subacute stage is associated with the 3-month functional outcome after acute ischemic stroke.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Fukuda, K., Kai, H., Kamouchi, M., Hata, J., Ago, T., Nakane, H., Imaizumi, T., Kitazono, T., on behalf of the FSR Investigators, The steering committee of the Fukuoka Stroke Registry included, Ishitsuka, Fujimoto, Ibayashi, Kusuda, Arakawa, Irie, Fujii, Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Role of Imaging in Current Acute Ischemic Stroke Workflow for Endovascular Therapy Understanding and Applying the Endovascular Trials
Ischemic stroke is caused by a thrombus that blocks an intracranial artery. Brain tissue beyond the blocked artery survives for a variable period of time because of blood and nutrients received through tiny vessels called collaterals. Imaging the brain and the vasculature that supplies it is therefore a vital first step in treating patients with acute ischemic stroke. In this review, we focus on current evidence for imaging selection of patients for endovascular therapy in the context of the recently positive clinical trials, such as Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke ...
Source: Stroke - May 22, 2015 Category: Neurology Authors: Menon, B. K., Campbell, B. C. V., Levi, C., Goyal, M. Tags: CT and MRI, Emergency treatment of Stroke Understanding and Applying the Endovascular Trials Source Type: research

Acute Reperfusion Therapy and Stroke Care in Asia After Successful Endovascular Trials Understanding and Applying the Endovascular Trials
The current status of and prospects for acute stroke care in Asia in the situation where both intravenous thrombolysis and endovascular therapies have been recognized as established strategies for acute stroke are reviewed. Of 15 million people annually having stroke worldwide, 9 million are Asians. The burdens of both ischemic and hemorrhagic strokes are severe in Asia. The unique features of stroke in Asia include susceptibility to intracranial atherosclerosis, high prevalence of intracerebral hemorrhage, effects of dietary and lifestyle habits, and several disorders with genetic causes. These features affect acute strok...
Source: Stroke - May 22, 2015 Category: Neurology Authors: Toyoda, K., Koga, M., Hayakawa, M., Yamagami, H. Tags: Emergency treatment of Stroke, Anticoagulants, Thrombolysis, Angioplasty and Stenting Understanding and Applying the Endovascular Trials Source Type: research

Mechanical Thrombectomy in Cerebral Venous Thrombosis: Systematic Review of 185 Cases Clinical Sciences
Conclusions— Our systematic review suggests that mechanical thrombectomy is reasonably safe but controlled studies are required to provide a definitive answer on its efficacy and safety in patients with cerebral venous thrombosis.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Siddiqui, F. M., Dandapat, S., Banerjee, C., Zuurbier, S. M., Johnson, M., Stam, J., Coutinho, J. M. Tags: Cerebral Venous Thrombosis, Thrombolysis Clinical Sciences Source Type: research

Nursing Best Practices to Prevent Stroke in Women State-of-the-Science Nursing Review
Source: Stroke - March 23, 2015 Category: Neurology Authors: Miller, E. T. Tags: Behavioral/psychosocial - stroke, Other hypertension, Thrombosis risk factors, Acute Cerebral Infarction, Other Stroke Treatment - Medical State-of-the-Science Nursing Review Source Type: research

Occult Anterograde Flow Is an Under-Recognized but Crucial Predictor of Early Recanalization With Intravenous Tissue-Type Plasminogen Activator Clinical Sciences
Conclusions— Occult anterograde flow through thrombus can be assessed by perfusion computed tomography T0 maps and predicts early recanalization with intravenous tissue-type plasminogen activator robustly.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Ahn, S. H., d'Esterre, C. D., Qazi, E. M., Najm, M., Rubiera, M., Fainardi, E., Hill, M. D., Goyal, M., Demchuk, A. M., Lee, T. Y., Menon, B. K. Tags: Fibrinolysis, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Validity of Shape as a Predictive Biomarker of Final Infarct Volume in Acute Ischemic Stroke Clinical Sciences
Conclusions— Our findings suggest that lesion shape contains important predictive information and reflects important environmental factors that might determine the progression of ischemia from the core.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Frindel, C., Rouanet, A., Giacalone, M., Cho, T.-H., Ostergaard, L., Fiehler, J., Pedraza, S., Baron, J.-C., Wiart, M., Berthezene, Y., Nighoghossian, N., Rousseau, D. Tags: Acute Cerebral Infarction, Brain Circulation and Metabolism Clinical Sciences Source Type: research

Distance to Thrombus in Acute Middle Cerebral Artery Occlusion: A Predictor of Outcome After Intravenous Thrombolysis for Acute Ischemic Stroke Clinical Sciences
Conclusion— DT is an independent predictor of clinical outcome in patients with acute MCA occlusion treated with IVT. In acute stroke with MCA occlusion confirmed by CT angiography and DT <16 mm, the likelihood of a good clinical outcome after treatment with IVT was exponentially <50%. This might warrant the evaluation of other therapy forms than IVT in patients with proximal MCA occlusion.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Friedrich, B., Gawlitza, M., Schob, S., Hobohm, C., Raviolo, M., Hoffmann, K.-T., Lobsien, D. Tags: Thrombolysis Clinical Sciences Source Type: research

Drip and Ship Thrombolytic Therapy for Acute Ischemic Stroke: Use, Temporal Trends, and Outcomes Clinical Sciences
Conclusions— Drip and ship tPA is common, used in 1 in 4 patients treated with tPA in the United States. Modest differences in mortality and symptomatic intracranial hemorrhage may be because of patient selection bias, post-tPA care differences, or unmeasured confounding. The drip and ship paradigm may facilitate widespread tPA use in patients with acute stroke.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Sheth, K. N., Smith, E. E., Grau-Sepulveda, M. V., Kleindorfer, D., Fonarow, G. C., Schwamm, L. H. Tags: Acute Cerebral Infarction, Acute Stroke Syndromes, Embolic stroke, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Tenecteplase-Tissue-Type Plasminogen Activator Evaluation for Minor Ischemic Stroke With Proven Occlusion Clinical Sciences
Conclusions— Administration of TNK–tissue-type plasminogen activator in minor stroke with intracranial occlusion is both feasible and safe. A larger randomized controlled trial is needed to prove that this treatment is efficacious. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01654445.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Coutts, S. B., Dubuc, V., Mandzia, J., Kenney, C., Demchuk, A. M., Smith, E. E., Subramaniam, S., Goyal, M., Patil, S., Menon, B. K., Barber, P. A., Dowlatshahi, D., Field, T., Asdaghi, N., Camden, M.-C., Hill, M. D., for the TEMPO-1 Investigators Tags: Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Letter by Turc et al Regarding Article, "Defining Clinically Relevant Cerebral Hemorrhage After Thrombolytic Therapy for Stroke: Analysis of the National Institute of Neurological Disorders and Stroke Tissue-Type Plasminogen Activator Trials" Letters to the Editor
Source: Stroke - January 26, 2015 Category: Neurology Authors: Turc, G., Tisserand, M., Seners, P., Oppenheim, C., Baron, J.-C. Tags: Thrombolysis Letters to the Editor Source Type: research

Response to Letter Regarding Article, "Defining Clinically Relevant Cerebral Hemorrhage After Thrombolytic Therapy for Stroke: Analysis of the National Institute of Neurological Disorders and Stroke Tissue-Type Plasminogen Activator Trials" Letters to the Editor
Source: Stroke - January 26, 2015 Category: Neurology Authors: Rao, N. M., Levine, S. R., Saver, J. L. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Emergency treatment of Stroke, Intracerebral Hemorrhage, Thrombolysis Letters to the Editor Source Type: research