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Source: Stroke
Condition: Thrombosis
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Total 230 results found since Jan 2013.
Patients With Undetermined Stroke Have Increased Atrial Fibrosis Brief Report
Conclusions—The LA phenotype that was found in patients with undetermined cause supports the hypothesis that an atrial disease may be associated with stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Ana Catarina Fonseca, Pedro Alves, Nuno Inacio, Joao Pedro Marto, Miguel Viana–Baptista, Teresa Pinho–e–Melo, Jose M. Ferro, Ana G. Almeida Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Embolism Brief Reports Source Type: research
Thrombus Neutrophil Extracellular Traps Content Impair tPA-Induced Thrombolysis in Acute Ischemic Stroke Brief Report
Conclusions—This study suggests that thrombus NETs content may be responsible for reperfusion resistance, including mechanical or pharmacological approaches with intravenous tPA, irrespectively of their etiology. The efficacy of a strategy involving an administration of DNAse 1 in addition to tPA should be explored in the setting of AIS.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02907736.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Celina Ducroux, Lucas Di Meglio, Stephane Loyau, Sandrine Delbosc, William Boisseau, Catherine Deschildre, Malek Ben Maacha, Raphael Blanc, Hocine Redjem, Gabriele Ciccio, Stanislas Smajda, Robert Fahed, Jean-Baptiste Michel, Michel Piotin, Laurence Salom Tags: Inflammation, Pathophysiology, Vascular Biology, Ischemic Stroke Brief Reports Source Type: research
Associations Between Collateral Status and Thrombus Characteristics and Their Impact in Anterior Circulation Stroke Clinical Sciences
Conclusions—Patients with lower thrombus burden and higher thrombus perviousness scores had higher collateral score. The positive effect of thrombus perviousness on clinical outcome was only present in patients with moderate and high collateral scores.Clinical Trial Registration—URL: http://www.trialregister.nl. Unique identifier: NTR1804 and URL: http://www.controlled-trials.com Unique identifier: ISRCTN10888758.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Heitor C. Alves, Kilian M. Treurniet, Bruna G. Dutra, Ivo G. H. Jansen, Anna M.M. Boers, Emilie M.M. Santos, Olvert A. Berkhemer, Diederik W.J. Dippel, Aad van der Lugt, Wim H. van Zwam, Robert J. van Oostenbrugge, Hester F. Lingsma, Yvo B.W.E.M. Roos, Al Tags: Computerized Tomography (CT), Ischemic Stroke Original Contributions Source Type: research
Cerebral Venous Thrombosis in Older Patients Brief Report
Background and Purpose—Cerebral venous thrombosis (CVT) is rare in older patients. We investigated whether clinical features and outcomes differ in older and younger patients.Methods—We used data from a multicenter observational registry of consecutive adult patients with CVT admitted between 1987 and 2016. We compared demographics, clinical manifestations, and outcomes between older (upper quartile of the age distribution) and younger (lower 3 quartiles of the age distribution) patients.Results—Data for 843 patients with CVT were available. The median age was 43 years (interquartile range, 30–55 years). Older pati...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Susanna M. Zuurbier, Sini Hiltunen, Erik Lindgren, Suzanne M. Silvis, Katarina Jood, Sharon Devasagayam, Timothy J. Kleinig, Frank L. Silver, Daniel M. Mandell, Jukka Putaala, Turgut Tatlisumak, Jonathan M. Coutinho Tags: Cerebrovascular Disease/Stroke, Thrombosis, Vascular Disease Brief Reports Source Type: research
Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Scientific Statement
Purpose—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on expert opinion and small case series, with the efficacy of such treatments not well established. This document aims to provide an overview of sICH with a focus on pathophysiology and treatment.Methods—A literature review was performed for randomized trials, prospective and retrospective studies, opinion papers, case series, and case reports on the definitions, epidemiology, risk factors, pathophysiology, treatment, and outcome of sICH. The documen...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Shadi Yaghi, Joshua Z. Willey, Brett Cucchiara, Joshua N. Goldstein, Nicole R. Gonzales, Pooja Khatri, Louis J. Kim, Stephan A. Mayer, Kevin N. Sheth, Lee H. Schwamm Tags: Statements and Guidelines AHA/ASA Scientific Statement Source Type: research
Letter by Musialek et al Regarding Article, “Acute Occlusions of Dual-Layer Carotid Stents After Endovascular Emergency Treatment of Tandem Lesions” Letter to the Editor
Source: Stroke - November 27, 2017 Category: Neurology Authors: Piotr Musialek, Ralf Kolvenbach, Joachim Schofer Tags: Revascularization, Stent, Treatment, Ischemic Stroke, Thrombosis Letters to the Editor Source Type: research
Imaging Characteristics of Venous Parenchymal Abnormalities Clinical Sciences
Conclusions—Parenchymal lesions caused by CVT display specific anatomic patterns, which is mainly determined by the site of venous occlusion.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Audrey Arnoux, Aude Triquenot–Bagan, Daniela Andriuta, David Wallon, Evelyne Guegan–Massardier, Claire Leclercq, Olivier Martinaud, Melody Castier–Amouyel, Olivier Godefroy, Jean–Marc Bugnicourt Tags: Magnetic Resonance Imaging (MRI), Thrombosis Original Contributions Source Type: research
Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin Clinical Sciences
Conclusions—In anticoagulated patients with atrial fibrillation and risk factors for stroke, echocardiographic findings do not seem to add to the risk of thromboembolic events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00412984.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Dragos Vinereanu, Renato D. Lopes, Hillary Mulder, Bernard J. Gersh, Michael Hanna, Pedro G.M. de Barros e Silva, Dan Atar, Lars Wallentin, Christopher B. Granger, John H. Alexander Tags: Arrhythmias, Echocardiography, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Sickle Mice Are Sensitive to Hypoxia/Ischemia-Induced Stroke but Respond to Tissue-Type Plasminogen Activator Treatment Basic Sciences
Conclusions—Sickle mice are sensitive to hypoxia/ischemia-induced cerebral infarct but benefit from thrombolytic treatment. An increased resistive index in carotid arteries may be an early marker of sickle cell vasculopathy.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Yu-Yo Sun, Jolly Lee, Henry Huang, Mary B. Wagner, Clinton H. Joiner, David R. Archer, Chia-Yi Kuan Tags: Animal Models of Human Disease, Basic Science Research Original Contributions Source Type: research
Inhibition of CD147 (Cluster of Differentiation 147) Ameliorates Acute Ischemic Stroke in Mice by Reducing Thromboinflammation Basic Sciences
Conclusions—Inhibition of CD147 ameliorates acute ischemic stroke by reducing thromboinflammation. CD147 might represent a novel and promising therapeutic target for ischemic stroke and possibly other thromboinflammatory disorders.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Rong Jin, Adam Y. Xiao, Rui Chen, D. Neil Granger, Guohong Li Tags: Basic Science Research, Ischemic Stroke Original Contributions Source Type: research
Safety of Pregnancy After Cerebral Venous Thrombosis Brief Report
Conclusions—In women with prior cerebral venous thrombosis, recurrent venous thrombotic events during subsequent pregnancies are infrequent.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Diana Aguiar de Sousa, Patricia Canhao, Isabelle Crassard, Jonathan Coutinho, Antonio Arauz, Adriana Conforto, Yannick Beȷot, Maurice Giroud, Jose M. Ferro, on behalf of the ISCVT–2–PREGNANCY Investigators* Tags: Pregnancy, Secondary Prevention, Cerebrovascular Disease/Stroke, Thrombosis Brief Reports Source Type: research
Letter by Li and Chen Regarding Article, “Impact of Thrombus Length on Outcomes After Intra-Arterial Aspiration Thrombectomy in the THERAPY Trial” Letter to the Editor
Source: Stroke - September 25, 2017 Category: Neurology Authors: Tiangui Li, Fang Chen Tags: Ischemic Stroke Letters to the Editor Source Type: research
Response by Yoo et al to Letter Regarding Article, “Impact of Thrombus Length on Outcomes After Intra-Arterial Aspiration Thrombectomy in the THERAPY Trial” Letter to the Editor
Source: Stroke - September 25, 2017 Category: Neurology Authors: Albert J. Yoo, Osama O. Zaidat, Rudiger von Kummer Tags: Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Letters to the Editor Source Type: research
Fibrin Clot Permeability as a Predictor of Stroke and Bleeding in Anticoagulated Patients With Atrial Fibrillation Clinical Sciences
Background and Purpose—Formation of denser fiber networks has been reported in atrial fibrillation and ischemic stroke. In this longitudinal cohort study, we evaluated whether fibrin clot density may predict thromboembolic and bleeding risk in patients with atrial fibrillation on vitamin K antagonists.Methods—In 236 patients with atrial fibrillation receiving vitamin K antagonists treatment, we measured ex vivo plasma clot permeability (Ks), a measure of the pore size in fibrin networks.Results—During a median follow-up of 4.3 (interquartile range, 3.7–4.8) years, annual rates of ischemic stroke or transient ischem...
Source: Stroke - September 25, 2017 Category: Neurology Authors: Leszek Drabik, Paweł Wołkow, Anetta Undas Tags: Atrial Fibrillation, Ischemic Stroke, Thrombosis Original Contributions Source Type: research
Response by Barreto and Grotta to Letter Regarding Article, “Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke)” Letter to the Editor
Source: Stroke - August 28, 2017 Category: Neurology Authors: Andrew D. Barreto, James C. Grotta Tags: Anticoagulants, Treatment, Cerebrovascular Disease/Stroke, Thrombosis Letters to the Editor Source Type: research
