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Source: Stroke
Condition: Thrombosis

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Total 230 results found since Jan 2013.

Brain Regulation of Thrombosis and Hemostasis: From Theory to Practice Basic Science Advances for Clinicians
Source: Stroke - October 21, 2013 Category: Neurology Authors: Fisher, M. J. Tags: Anticoagulant mechanisms, Coagulation and fibronolysis, Platelets, Endothelium/vascular type/nitric oxide Basic Science Advances for Clinicians Source Type: research

Fog on the Crystal Ball? Missing Atrial Fibrillation in Forecasting the Future of Stroke Letters to the Editor
Source: Stroke - September 23, 2013 Category: Neurology Authors: Neubeck, L., Orchard, J., Freedman, S. B. Tags: Thrombosis risk factors, Embolic stroke Letters to the Editor Source Type: research

Incidence of Venous Thromboembolism in the Wake of the Clots in Legs Or sTockings after Stroke (CLOTS) Study Brief Reports
Conclusions— Discontinuation of compressive stockings did not increase venous thromboembolism incidence. There was a trend toward more deep vein thrombosis and fewer PEs after CLOTS, which might be because of increased clinical vigilance in the diagnosis of deep vein thrombosis, but a chance variation cannot be excluded.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Jain, P., Ward, E., Nevatte, T., Roffe, C. Tags: Deep vein thrombosis Brief Reports Source Type: research

Thrombolysis for Ischemic Stroke Associated With Infective Endocarditis: Results From the Nationwide Inpatient Sample Brief Reports
Conclusions— High rates of post-thrombolytic intracerebral hemorrhage and low rates of favorable outcome mandate caution in using IVT in acute ischemic stroke patients with IE.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Asaithambi, G., Adil, M. M., Qureshi, A. I. Tags: Embolic stroke, Thrombolysis Brief Reports Source Type: research

Predictors of Stroke in Patients With Impaired Glucose Tolerance: Results From the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research Trial Brief Reports
Conclusions— The most powerful predictors of stroke in patients with impaired glucose tolerance included a combination of established risk factors and novel variables, such as previous venous thromboembolism and elevated waist circumference, allowing moderately effective identification of high-risk individuals.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Preiss, D., Giles, T. D., Thomas, L. E., Sun, J.-L., Haffner, S. M., Holman, R. R., Standl, E., Mazzone, T., Rutten, G. E., Tognoni, G., Chiang, F.-T., McMurray, J. J. V., Califf, R. M. Tags: Cerebrovascular disease/stroke, Risk Factors, Glucose intolerance Brief Reports Source Type: research

Unequal Access to Treatment With Intravenous Alteplase for Women With Acute Ischemic Stroke Brief Reports
Conclusions— Fewer women present themselves within 4 hours from stroke onset than men and consequently less often receive thrombolytic treatment. This difference may be caused by the older age of women on average and consequently women more often living alone. Clinical Trial Registration— URL: http://www.controlled-trials.com. Unique identifier: ISRCTN20405426.
Source: Stroke - August 26, 2013 Category: Neurology Authors: de Ridder, I., Dirks, M., Niessen, L., Dippel, D., on behalf of the PRACTISE Investigators Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Brief Reports Source Type: research

Role of Balloon-Expandable Stents in Intracranial Atherosclerotic Disease in a Series of 182 Patients Brief Reports
Conclusions— Treatment of intracranial atherosclerotic disease with balloon-expandable intracranial stents is a safe and effective method with acceptable adverse events, especially in patients who failed medical therapy and were symptomatic despite being on optimum medical therapy.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Alurkar, A., Karanam, L. S. P., Oak, S., Nayak, S., Sorte, S. Tags: Angiography, Angioplasty and Stenting, Other Stroke Brief Reports Source Type: research

CLOTBUST-Hands Free: Initial Safety Testing of a Novel Operator-Independent Ultrasound Device in Stroke-Free Volunteers Clinical Sciences
Conclusions— Our novel device was well tolerated by stroke-free volunteers and did not cause any neurological dysfunction nor did it affect blood brain barrier integrity. The safety and efficacy of the device are now being tested in stroke patients receiving intravenous tissue-type plasminogen activator in phase II–III clinical trials.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Barlinn, K., Barreto, A. D., Sisson, A., Liebeskind, D. S., Schafer, M. E., Alleman, J., Zhao, L., Shen, L., Cava, L. F., Rahbar, M. H., Grotta, J. C., Alexandrov, A. V. Tags: Other Treatment, Acute Cerebral Infarction, Doppler ultrasound, Transcranial Doppler etc. Clinical Sciences Source Type: research

Thrombolysis Despite Recent Stroke: A Case Series Brief Reports
Conclusions— In our center, we thrombolysed 6 patients despite recent stroke. Three patients had asymptomatic petechial hemorrhagic transformation within the area of subacute infarct, without apparent neurological worsening. Prospective studies are needed to explore the possible safety of tissue-type plasminogen activator in the context of previous subacute stroke in otherwise eligible patients.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Alhazzaa, M., Sharma, M., Blacquiere, D., Stotts, G., Hogan, M., Dowlatshahi, D. Tags: Acute Cerebral Infarction, Thrombolysis Brief Reports Source Type: research

Evidence-Basis for Anticoagulants for Cerebral Sinus Venous Thrombosis? Letter to the Editor
Source: Stroke - May 24, 2013 Category: Neurology Authors: Cundiff, D. K. Tags: Heparin, Coumarins, Other anticoagulants, Cerebral Venous Thrombosis, Anticoagulants Letter to the Editor Source Type: research

Response to Evidence-Basis for Anticoagulants for Cerebral Sinus Venous Thrombosis? Letter to the Editor
Source: Stroke - May 24, 2013 Category: Neurology Authors: Coutinho, J. M., Bousser, M.-G., Stam, J. Tags: Coagulation, Heparin, Cerebral Venous Thrombosis, Anticoagulants Letter to the Editor Source Type: research

Smoking-Thrombolysis Paradox: Recanalization and Reperfusion Rates After Intravenous Tissue Plasminogen Activator in Smokers With Ischemic Stroke Original Contributions
Conclusions— Smoking is independently associated with recanalization and reperfusion, indicating that thrombolytic therapy acts more effectively in smokers; because of small numbers, these results should be considered preliminary. Clinical Trial Registration— URL: http://clinicaltrials.gov. Unique Identifier: NCT00715533.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Kufner, A., Nolte, C. H., Galinovic, I., Brunecker, P., Kufner, G. M., Endres, M., Fiebach, J. B., Ebinger, M. Tags: Fibrinolysis, Angiography, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke, Thrombolysis Original Contributions Source Type: research

Fingolimod Reduces Hemorrhagic Transformation Associated With Delayed Tissue Plasminogen Activator Treatment in a Mouse Thromboembolic Model Basic Sciences
Conclusion— This study confirms the protective efficacy of fingolimod as a treatment against ischemic stroke in another rodent model of stroke (thromboembolic occlusion), and suggests that fingolimod could potentially be used in combination with tPA to reduce the risk of brain hemorrhage.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Campos, F., Qin, T., Castillo, J., Seo, J. H., Arai, K., Lo, E. H., Waeber, C. Tags: Acute Cerebral Infarction, Embolic stroke, Emergency treatment of Stroke, Thrombolysis, Other Stroke Treatment - Medical Basic Sciences Source Type: research

The Effects of Alteplase 3 to 6 Hours After Stroke in the EPITHET-DEFUSE Combined Dataset: Post Hoc Case-Control Study Original Contributions
Conclusions— The data provide further evidence that alteplase significantly attenuates infarct growth and increases reperfusion compared with placebo in the 3- to 6- hour time window in patients selected based on MR penumbral imaging. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00238537
Source: Stroke - December 24, 2012 Category: Neurology Authors: Ogata, T., Christensen, S., Nagakane, Y., Ma, H., Campbell, B. C. V., Churilov, L., Lansberg, M. G., Straka, M., De Silva, D. A., Mlynash, M., Bammer, R., Olivot, J.-M., Desmond, P. M., Albers, G. W., Davis, S. M., Donnan, G. A., for the EPITHET and DEFUS Tags: CT and MRI, Other imaging, Thrombolysis Original Contributions Source Type: research

CXCR4 Antagonist AMD3100 Protects Blood-Brain Barrier Integrity and Reduces Inflammatory Response After Focal Ischemia in Mice Original Contributions
Conclusions— CXCR4 antagonist AMD3100 significantly suppressed inflammatory response and reduced blood–brain barrier disruption after MCAO. AMD3100 attenuated ischemia-induced acute inflammation by suppressing leukocyte migration and infiltration, in addition to reducing proinflammatory cytokine expression in the ischemic region.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Huang, J., Li, Y., Tang, Y., Tang, G., Yang, G.-Y., Wang, Y. Tags: Animal models of human disease, Arterial thrombosis, Acute Cerebral Infarction, Behavioral Changes and Stroke, Brain Circulation and Metabolism, Other Stroke Treatment - Medical, Other Research Original Contributions Source Type: research