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E-108 Endovascular treatment of patients with acute ischemic stroke due to underlying arterial dissection: a nationwide analysis
ConclusionsDespite a similar prevalence among patients admitted for AIS, CA dissections are associated with a higher rate of endovascular intervention and poorer short-term outcomes compared to VA dissections. This study provides essential epidemiologic and outcome data for the cerebrovascular neurosurgeon.Abstract E-108 Table 1Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections Characteristic Vertebral Artery Dissection, N = 2,562 Carotid Artery Dissection, N = 2,789 p-value1 Age (years), Mean (SD) 53 (17) 57 (17) <0.00...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., McCann, C., Wali, A., Wu, V., Esmail, S., Steinberg, J., Olson, S., Pannell, J., Khalessi, A., Santiago-Dieppa, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

China stroke surveillance report 2021
AbstractSince 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China Stroke High-risk Population Screening and Intervention Program, an estimated 17.8 million [95% confidence interval (CI) 17.6 –18.0 million] adults in China had experienced a stroke in 2020, with 3.4 million (95% CI 3.3–3.5 million) experiencing their first-ever stroke and another 2.3 million (95% CI 2.2–2.4 million) dying as a result. Additionally, approximately 12.5% (95% CI 12.4–12.5%) of stroke survi...
Source: Military Medical Research - July 19, 2023 Category: International Medicine & Public Health Source Type: research

Endovascular thrombectomy for distal vessel occlusion stroke: Single-center experience
CONCLUSION: This single-center real-world experience demonstrates that EVT in patients with DVO stroke is safe and feasible and may lead to improved clinical outcome.PMID:36999213 | DOI:10.1177/15910199231162670
Source: Interventional Neuroradiology - March 31, 2023 Category: Radiology Authors: Stavros Matsoukas Santiago Gomez Paz Christopher P Kellner Reade De Leacy Johanna T Fifi J Mocco Shahram Majidi Source Type: research

P-007 Safety and efficacy of endovascular thrombectomy for distal vessel occlusion (DLV): single center experience
ConclusionThis single center, consecutive real-world experience demonstrates that thrombectomy in DVO stroke patients is safe and leads to high rate of successful recanalization. Further studies are warranted to evaluate the efficacy of thrombectomy in DVO in comparison to best medical management.Disclosures S. Majidi: None. S. Matsoukas: None. R. De Leacy: None. T. Oxley: None. H. Shoirah: None. T. Shigematsu: None. C. Kellner: None. J. Fifi: None. J. Mocco: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Majidi, S., Matsoukas, S., De Leacy, R., Oxley, T., Shoirah, H., Shigematsu, T., Kellner, C., Fifi, J., Mocco, J. Tags: Oral poster abstracts Source Type: research

Temporal Trends and Predictors of Drug Utilization and Outcomes in First-Ever Stroke Patients: A Population-Based Study Using the Singapore Stroke Registry
ConclusionsPrescription of secondary stroke preventive medications (particularly in ischemic stroke) was associated with more favorable outcomes, highlighting the importance of physician adherence to evidence-based pharmacotherapy.
Source: CNS Drugs - July 15, 2019 Category: Neurology Source Type: research

Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course
Conclusions: Frequency of hemorrhagic transformation in Routine follow-up brain imaging and consecutive changes in therapeutic management were different depending on clinical course measured by NHISS score. Introduction Brain imaging 24–36 h after systemic thrombolysis for acute ischemic stroke is recommended in American Stroke Association and European Stroke Organization guidelines (1, 2). Brain imaging is performed to detect secondary bleeding or hemorrhagic transformation in order to adapt medical stroke prevention if necessary. Guideline recommendations are based on the results of the first study on rt-PA...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II
Conclusion: In ischemic stroke or TIA patients with platelet count within normal range, platelet count may be a qualified predictor for long-term recurrent stroke, mortality, and poor functional outcome. Introduction Platelets exert a critical role in the pathogenesis of atherosclerotic complications of cardio-cerebrovascular disease, contributing to thrombus formation, and embolism (1, 2). Previous literature reported that platelets of various size and density are produced by megakaryocytes of different size and stages of maturation in different clinical conditions, suggesting various platelet patterns in differen...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Angiogram-negative subarachnoid hemorrhage after intravenous thrombolysis in a patient with acute ischemic stroke
We describe a patient with SAH immediately after thrombolytic therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Kyung-Hee Cho, Jae-Gyum Kim, Sungwook Yu, Kyung-Hee Cho Source Type: research

Electrocardiographic differentiation between takotsubo syndrome and acute myocardial infarction
It is crucial to differentiate between acute myocardial infarction (AMI), particularly of the ST-segment elevation (STE) AMI variety, and takotsubo syndrome (TTS), in order as swiftly as possible to implement thrombolytic therapy and/or percutaneous coronary interventions for the former. Also the potential benefits accrued by such an early diagnostic differentiation has a bearing on the urgency and timing of coronary arteriography, and the use of antiplatelet/anticoagulation regimen, particularly in patients “with multiple comorbidities such as those presenting after physical stressors such as subarachnoid hemorrhage or ...
Source: International Journal of Cardiology - August 7, 2016 Category: Cardiology Authors: John E. Madias Source Type: research

Validation of Stroke and Thrombolytic Therapy in Korean National Health Insurance Claim Data.
CONCLUSIONS: Discharge with hemorrhagic stroke and use of thrombolytic therapy were identified with high reliability in administrative discharge data. A substantial level of agreement was also obtained for IS, despite variation between the algorithms and data sets. PMID: 26365022 [PubMed - as supplied by publisher]
Source: Journal of Clinical Neurology - September 15, 2015 Category: Neurology Tags: J Clin Neurol Source Type: research

The Case Files: Traumatic Carotid Dissection
By Hsiao, Jonie MD   A 30-year-old man who was right-hand dominant presented 10 days after sustaining left-sided face and head trauma from a fall from a skateboard at an unknown speed. He lost consciousness for several seconds, and initially developed a headache with nausea and vomiting. A non-contrast head CT performed at another hospital done two days after the incident was reportedly negative.   He now presents primarily with concerns about the appearance of his left eye. He has notable anisocoria and a droopy eyelid. His left pupil is notably smaller, 2 mm, compared with the right eye, 5 mm. Both are reactive. The re...
Source: The Case Files - June 4, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

The PLAN score predicted death and severe disability in patients with acute ischemic stroke.
CONCLUSION The 9-item PLAN score based on data collected at hospital admission predicted death and severe disability in patients with acute ischemic stroke.PLAN score for predicting death and severe disability in patients hospitalized with acute ischemic stroke*PLAN score rangeNumber of patientsOutcomes (range)30-d mortality1-y mortalityDeath or severe disability at discharge†&lt; 1048440.7% to 4.4%2.1% to 13%0.9% to 4.3%10 to 1224454.4% to 11%16% to 26%6.0% to 15%13 to 15126715% to 29%32% to 46%20% to 36%&gt; 15129135% to 66%58% to 84%44% to 78%*PLAN = Preadmission comorbid conditions, Level of consciousness, ...
Source: Annals of Internal Medicine - February 19, 2013 Category: Internal Medicine Authors: Rowland K Tags: Ann Intern Med Source Type: research

Stroke Incidence and Usage Rate of Thrombolysis in A Japanese Urban City: The Kurashiki Stroke Registry
Conclusion: In this urban Japanese city, the age-adjusted incidence of first-ever stroke between March 2009 and February 2010 was 60.7 per 100,000 residents, which was relatively low compared with findings for other countries. Thrombolysis was given to approximately 5% of patients with acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2011 Category: Neurology Authors: Yasuyuki Iguchi, Kazumi Kimura, Keiichi Sone, Hiroshi Miura, Hiroshi Endo, Sen Yamagata, Hisashi Koide, Kenji Suzuki, Tomoichiro Kimura, Masaru Sakurai, Nobuya Mishima, Kenji Yoshii, Hiroyuki Fujisawa, Sunao Ebisutani, Kurashiki Stroke Registry investigat Tags: Original Articles Source Type: research