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Specialty: Biomedical Science
Condition: Hemorrhagic Stroke

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Total 187 results found since Jan 2013.

Short telomere length in blood leukocytes contributes to the presence of atherothrombotic stroke and hemorrhagic stroke and risk of post-stroke death
Conclusions—Shorter telomere length may serve as a potential marker for the presence of atherothrombotic and hemorrhagic stroke and for the risk of post-stroke death.
Source: Clinical Science - January 16, 2013 Category: Biomedical Science Authors: W Zhang, Y Chen, Y Wang, P Liu, M Zhang, C Zhang, F B Hu, R Hui Source Type: research

Quality Improvement in Acute Ischemic Stroke Care in Taiwan: The Breakthrough Collaborative in Stroke
by Fang-I Hsieh, Jiann-Shing Jeng, Chang-Ming Chern, Tsong-Hai Lee, Sung-Chun Tang, Li-Kai Tsai, Hsun-Hsiang Liao, Hang Chang, Kenneth A. LaBresh, Hung-Jung Lin, Hung-Yi Chiou, Hou-Chang Chiu, Li-Ming Lien, for the BTS-Stroke Investigators In the management of acute ischemic stroke, guideline adherence is often suboptimal, particularly for intravenous thrombolysis or anticoagulation for atrial fibrillation. We sought to improve stroke care quality via a collaborative model, the Breakthrough Series (BTS)-Stroke activity, in a nationw ide, multi-center activity in Taiwan. A BTS Collaborative, a short-term learning system fo...
Source: PLoS One - August 2, 2016 Category: Biomedical Science Authors: Fang-I Hsieh Source Type: research

Association between the sarcopenia index and the risk of stroke in elderly patients with hypertension: a cohort study
This study included 5145 stroke-free elderly hypertensive patients. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of incident stroke. Over a median follow-up of 38 months, we identified 607 (11.80%) individuals with total stroke, of whom 507 (9.85%) had ischemic stroke and 93 (1.81%) had hemorrhagic stroke. The risk of developing stroke decreased with each quartile of SI; after adjustment for multiple confounders, the HRs for the Q4 group versus the Q1 group were 0.46 (95% CI, 0.35-0.59) for total stroke, 0.46 (95% CI, 0.35-0.61) for ischemic stroke, and 0.33 (95% CI, 0.17...
Source: Aging - March 29, 2023 Category: Biomedical Science Authors: Xintian Cai Junli Hu Mengru Wang Wen Wen Jingyu Wang Wenbo Yang Yujie Dang Qin Luo Jing Hong Nanfang Li Source Type: research

Acute Stroke Care in Korea in 2013-2014: National Averages and Disparities.
CONCLUSION: This study describes the current status of acute stroke care in Korea. Despite quite acceptable quality of stroke care, it suggests regional and hospital disparities. Expansion of stroke units, stroke center certification or accreditation, and connections between stroke centers and emergency medical services are highly recommended. PMID: 32449325 [PubMed - in process]
Source: Journal of Korean Medical Science - May 26, 2020 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Clinical Manifestation of Depression after Stroke: Is It Different from Depression in Other Patient Populations?
Conclusions The findings suggest that depression after stroke is not a different type of depression. This finding indicates that all depressive symptoms should be evaluated in stroke patients, including somatic symptoms.
Source: PLoS One - December 4, 2015 Category: Biomedical Science Authors: Janneke M. de Man-van Ginkel et al. Source Type: research

EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke.
CONCLUSIONS: Acute inhibition of CD147 decreases levels of MMP-9, limits tissue loss, and improves long-term cognitive outcomes following experimental stroke in aged mice. High serum CD147 correlates with poor outcomes in stroke patients. This study identifies CD147 as a novel, clinically relevant target in ischemic stroke. PMID: 32191628 [PubMed - as supplied by publisher]
Source: Aging - March 18, 2020 Category: Biomedical Science Authors: Patrizz A, Doran SJ, Chauhan A, Ahnstedt H, Roy-O'Reilly M, Lai YJ, Weston G, Tarabishy S, Patel AR, Verma R, Staff I, Kofler JK, Li J, Liu F, Ritzel RM, McCullough LD Tags: Aging (Albany NY) Source Type: research

Research Articles An MD2-perturbing peptide has therapeutic effects in rodent and rhesus monkey models of stroke
Studies have failed to translate more than 1000 experimental treatments from bench to bedside, leaving stroke as the second leading cause of death in the world. Thrombolysis within 4.5 hours is the recommended therapy for stroke and cannot be performed until neuroimaging is used to distinguish ischemic stroke from hemorrhagic stroke. Therefore, finding a common and critical therapeutic target for both ischemic and hemorrhagic stroke is appealing. Here, we report that the expression of myeloid differentiation protein 2 (MD2), which is traditionally regarded to be expressed only in microglia in the normal brain, was markedly...
Source: Science Translational Medicine - June 9, 2021 Category: Biomedical Science Authors: Fang, Z., Wu, D., Deng, J., Yang, Q., Zhang, X., Chen, J., Wang, S., Hu, S., Hou, W., Ning, S., Ding, Y., Fan, Z., Jiang, Z., Kang, J., Liu, Y., Miao, J., Ji, X., Dong, H., Xiong, L. Tags: Research Articles Source Type: research

Antipsychotic medications and stroke in schizophrenia: A case-crossover study
ConclusionsUse of second-generation antipsychotic drugs appeared to be associated with an increased risk of ischemic stroke in the patients studied, possibly mediated by high affinity for histamine-1 receptor blockade. Further research regarding the underlying biological mechanism and drug safety is suggested.
Source: PLoS One - June 14, 2017 Category: Biomedical Science Authors: Wen-Yin Chen Source Type: research

The efficacy and safety of Hirudin plus Aspirin versus Warfarin in the secondary prevention of Cardioembolic Stroke due to Nonvalvular Atrial Fibrillation: A multicenter prospective cohort study.
Conclusion: Significant difference in efficacy was not detected between warfarin group and hirudin plus aspirin group. Compared with warfarin, hirudin plus aspirin therapy had lower safety risk in the secondary prevention of cardioembolic stroke due to NVAF. PMID: 33526977 [PubMed - in process]
Source: International Journal of Medical Sciences - February 3, 2021 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Development-assistance Strategies for Stroke in Low- and Middle-income Countries.
Authors: Lee H, Nam YS, Lee KM Abstract While communicable diseases still pose a serious health threat in developing countries, previously neglected health issues caused by non-communicable diseases such as stroke are rapidly becoming a major burden to these countries. In this review we will discuss the features and current status of stroke in low- and middle-income countries (LMICs). Overall the global burden of hemorrhagic stroke is larger than ischemic stroke, with a disproportionately greater burden, measured in incidence and disability-adjusted life-years, regionally localized in LMICs. Patients in poorer coun...
Source: Journal of Korean Medical Science - December 1, 2015 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Stroke risk in arthritis: A systematic review and meta-analysis of cohort studies
by Wei Liu, Wei Ma, Hua Liu, Chunyan Li, Yangwei Zhang, Jie Liu, Yu Liang, Sijia Zhang, Zhen Wu, Chenghao Zang, Jianhui Guo, Liyan Li Background and objectiveStroke is a major contributor to the global burden of disease. Although numerous modifiable risk factors (RF) for stroke have been identified, some remain unexplained. Increasing studies have investigated stroke risk in arthritis, but their results are inconsistent. We aimed to synthesize, quantify, and compare the risk of stroke for the major types of arthritis in cohort studies by using a systematic review and meta-analysis approach. MethodsWe searched Chinese and E...
Source: PLoS One - March 16, 2021 Category: Biomedical Science Authors: Wei Liu Source Type: research

Body mass index and stroke risk among patients with diabetes mellitus in Korea
ConclusionBMI was positively associated with the overall risk of stroke among DM patients in Korea. The risk of ischemic stroke was higher in obese patients compared to overweight or normal-weight patients. However, the risk of hemorrhagic stroke was higher in slimmer patients compared with overweight or obese patients.
Source: PLoS One - September 30, 2022 Category: Biomedical Science Authors: Do Kyeong Song Source Type: research

Proportion of stroke types in Madagascar: A tertiary-level hospital-based case series
ConclusionsOur study is the first to report the proportion of stroke types and known risk factors in Madagascar. We find that the proportion of hemorrhagic strokes was unexpectedly higher than that reported from other countries in sub-Saharan Africa. Our findings highlight the need for a country-specific approach to stroke prevention, treatment, and rehabilitation and provide guidance on public health resource allocation in Madagascar.
Source: PLoS One - October 14, 2022 Category: Biomedical Science Authors: Julia Riedmann Source Type: research

Combined Effects of Family History of Cardiovascular Disease and Serum C-reactive Protein Level on the Risk of Stroke: A 9.2-year Prospective Study among Mongolians in China.
CONCLUSION: Participants with both a family history of CVD and high CRP levels had the highest stroke incidence, suggesting that high CRP levels may increase stroke risk, especially of ischemic stroke, among individuals with a family history of CVD. PMID: 29081337 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - September 1, 2017 Category: Biomedical Science Authors: Zhu ZB, Huangfu XF, Zhong CK, Zhou YP, Tian YF, Buren B, Xu T, Wang AL, Li HM, Zhang MZ, Zhang YH Tags: Biomed Environ Sci Source Type: research