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Effect of Variation in Published Stroke Rates on the Net Clinical Benefit of Anticoagulation for Atrial Fibrillation.
Conclusion: Variation in published AF stroke rates for patients not receiving anticoagulant therapy results in multifold variation in the net clinical benefit of anticoagulation. Guidelines should better reflect the uncertainty in current thresholds of stroke risk score for recommending anticoagulation. Primary Funding Source: None. PMID: 30264130 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - September 25, 2018 Category: Internal Medicine Authors: Shah SJ, Eckman MH, Aspberg S, Go AS, Singer DE Tags: Ann Intern Med Source Type: research

Carotid Endarterectomy After Intracranial Endovascular Thrombectomy for Acute Ischaemic Stroke in Patients with Carotid Artery Stenosis
CONCLUSION: These results indicate that CEA is safe to perform after previous successful EVT for acute ischaemic stroke. Results were comparable with those undergoing CEA only, despite the EVT+CEA patients having more severe stroke symptoms prior to surgery, and timing was similar.PMID:34887207 | DOI:10.1016/j.ejvs.2021.10.034
Source: PubMed: Eur J Vasc Endovasc ... - December 10, 2021 Category: Surgery Authors: Magnus Jonsson Ellinoora Aro Katarina Bj örses Staffan Holmin Petra Ij äs Nicolas Martinez-Majander Pirkka Vikatmaa Carl-Magnus Wahlgren Maarit Venermo Martin Bj örck Source Type: research

Death and ADL Dependency After Scoring Zero on the NIHSS: A Swedish Retrospective Registry-Based Study
Discussion One of 17 patients has either died or become ADL-dependent 3 months after a 0-NIHSS stroke, stressing that these strokes are not always benign. Older and physically inactive patients are at greater risk of an adverse outcome.
Source: Neurology Clinical Practice - September 1, 2023 Category: Neurology Authors: Darehed, D., Reinholdsson, M., Viktorisson, A., Abzhandadze, T., Sunnerhagen, K. S. Tags: Outcome research, All Cerebrovascular disease/Stroke, Cohort studies Research Article Source Type: research

Sex as predictor for achieved health outcomes and received care in ischemic stroke and intracerebral hemorrhage: a register-based study
ConclusionsA lower proportion of women had good functioning, a difference that remained in IS after adjustments for age, socioeconomic factors, living arrangements, ADL dependency, and stroke severity. The amount of received hospital care was lower for women after adjustments. Whether shorter hospital stay results in lower function or is a consequence of lower function cannot be elucidated. One-year survival was higher in men when no adjustments were made but lower after adjustments. This likely reflects that women were older at time of stroke, had more severe strokes, and more disability pre-stroke —factors that make a ...
Source: Biology of Sex Differences - March 7, 2018 Category: Biology Source Type: research

Prestroke physical activity and outcomes after intracerebral haemorrhage in comparison to ischaemic stroke: protocol for a matched cohort study (part of PAPSIGOT)
Introduction Piling evidence suggests that a higher level of prestroke physical activity can decrease stroke severity, and reduce the risk of poststroke mortality. However, prior studies have only included ischaemic stroke cases, or a majority of such. We aim to investigate how premorbid physical activity influences admission stroke severity and poststroke mortality in patients with intracerebral haemorrhage, compared with ischaemic stroke. A prespecified analysis plan counteract some inherent biases in observational studies, and promotes transparency. Methods and analysis This is a statistical analysis protocol for a mat...
Source: BMJ Open - November 19, 2021 Category: General Medicine Authors: Viktorisson, A., Buvarp, D., Sunnerhagen, K. S. Tags: Open access, Neurology Source Type: research

Blood pressure levels and risk of haemorrhagic stroke in patients with atrial fibrillation and oral anticoagulants: results from The Swedish Primary Care Cardiovascular Database of Skaraborg
Conclusion: In this cohort of primary care patients with hypertension and atrial fibrillation, we found that baseline SBP in the 145–180 mmHg range, prior to initiation of OAC, was associated with a more than doubled risk of haemorrhagic stroke, as compared with an SBP of 130 mmHg. This suggests that lowering SBP to below 145 mmHg, prior to initiation of OAC, may decrease the risk of haemorrhagic stroke in patients with hypertension and atrial fibrillation.
Source: Journal of Hypertension - July 9, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Calcium and magnesium in drinking water and risk of myocardial infarction and stroke —a population-based cohort study
ConclusionsDrinking water with a high concentration of calcium and magnesium, particularly magnesium, may lower the risk of stroke in postmenopausal women.
Source: American Journal of Clinical Nutrition - July 11, 2022 Category: Nutrition Source Type: research

BMI increase through puberty and adolescence is associated with risk of adult stroke
Conclusions: BMI increase through puberty and adolescence is associated with risk of adult IS and ICH in men. We propose that greater BMI increases during puberty contribute to increased risk of adult stroke at least partly via increased blood pressure.
Source: Neurology - July 24, 2017 Category: Neurology Authors: Ohlsson, C., Bygdell, M., Sonden, A., Jern, C., Rosengren, A., Kindblom, J. M. Tags: All Pediatric, Adolescence, Cohort studies, Infarction, Intracerebral hemorrhage ARTICLE Source Type: research

Calcium and magnesium in drinking water and risk of myocardial infarction and stroke - a population-based cohort study
CONCLUSION: Drinking water with a high concentration of calcium and magnesium, particularly magnesium, may lower the risk of stroke in postmenopausal women.PMID:35816459 | DOI:10.1093/ajcn/nqac186
Source: The American Journal of Clinical Nutrition - July 11, 2022 Category: Nutrition Authors: Emilie Helte Melle S äve-Söderbergh Susanna C Larsson Agneta Åkesson Source Type: research

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